IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
Found 98 products of "IGF-1R"
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NBI-31772 hydrate
NBI-31772 hydrate blocks IGF and IGFBPs binding, freeing IGF-I with Ki 1-24 nM; it has anxiolytic and antidepressant effects.Formula:C17H13NO8Color and Shape:SolidMolecular weight:372.82Linsitinib
CAS:OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth and inducing cell death.Formula:C26H23N5OPurity:99.71% - ≥95%Color and Shape:SolidMolecular weight:421.49AZD-3463
CAS:AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95AZ7550
CAS:AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formula:C27H31N7O2Purity:97.07% - 99.75%Color and Shape:SolidMolecular weight:485.58MID-1
CAS:MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.Formula:C12H11N3O4SPurity:99.39%Color and Shape:SolidMolecular weight:293.3Ref: TM-T8773
1mg52.00€5mg92.00€10mg138.00€25mg245.00€50mg363.00€100mg515.00€200mg700.00€1mL*10mM (DMSO)103.00€BRD7552
CAS:BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.Formula:C33H33N3O15Purity:>99.99% - ≥98%Color and Shape:SolidMolecular weight:711.63Sari 59-801
CAS:Sari 59-801 is a novel, orally effective hypoglycemic compound that appears to act largely by stimulation of insulin release.Formula:C18H23N3O2Purity:99.92%Color and Shape:SolidMolecular weight:313.39Ref: TM-T34532
1mg34.00€5mg107.00€10mg167.00€25mg263.00€50mg366.00€100mg492.00€1mL*10mM (DMSO)108.00€Glymidine
CAS:Glycodiazine, a sulfadiazine derivative, reduces blood sugar by boosting insulin release and sensitivity.Formula:C13H15N3O4SColor and Shape:SolidMolecular weight:309.34GIP (1-30) amide, porcine acetate
GIP (1-30) amide, porcine is a GIP receptor agonist that stimulates insulin and mildly inhibits gastric acid.Formula:C164H249N41O49SPurity:98.50%Color and Shape:SolidMolecular weight:3611.04Glymidine sodium
CAS:Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.Formula:C13H14N3NaO4SPurity:98.19%Color and Shape:SolidMolecular weight:331.32PQ401 hydrochloride (196868-63-0(free base))
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.Formula:C18H17Cl2N3O2Purity:99.86%Color and Shape:SolidMolecular weight:378.25Insulin (human)
CAS:Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood.Formula:C257H383N65O77S6Purity:97.32% - 99.99%Color and Shape:SolidMolecular weight:5807.57MSDC 0160
CAS:MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.Formula:C19H18N2O4SPurity:98.11% - 99.53%Color and Shape:SolidMolecular weight:370.42Ref: TM-T2607
1mg34.00€2mg48.00€5mg73.00€10mg94.00€25mg145.00€50mg187.00€100mg333.00€1mL*10mM (DMSO)78.00€MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formula:C21H18N2OPurity:98.53%Color and Shape:SolidMolecular weight:314.38XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg52.00€2mg73.00€5mg94.00€10mg141.00€25mg244.00€50mg371.00€100mg552.00€1mL*10mM (DMSO)104.00€Ceritinib dihydrochloride
CAS:Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase with antitumour effect.Formula:C28H38Cl3N5O3SPurity:99.85% - 99.99%Color and Shape:SolidMolecular weight:631.06Ceritinib
CAS:Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.Formula:C28H36ClN5O3SPurity:98.52% - 99.77%Color and Shape:SolidMolecular weight:558.14Picropodophyllin
CAS:Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.Formula:C22H22O8Purity:98.38% - 99.83%Color and Shape:SolidMolecular weight:414.41Ref: TM-T6943
5mg64.00€10mg88.00€25mg170.00€50mg316.00€100mg535.00€500mg1,121.00€1mL*10mM (DMSO)69.00€BMS-536924
CAS:BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormula:C25H26ClN5O3Purity:99.02%Color and Shape:SolidMolecular weight:479.96GSK1904529A
CAS:GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .Formula:C44H47F2N9O5SPurity:98.2% - 99.76%Color and Shape:SolidMolecular weight:851.96
