IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
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NVP-AEW541
CAS:475489-16-8
NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and …
Formula:
C27H29N5O
Purity:
96.03% - 99.55%
Color and Shape:
Solid
Molecular weight:
439.55
Ref: TM-T6080
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 267.00 € | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
NVP-ADW742
CAS:475488-23-4
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against …
Formula:
C28H31N5O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
453.58
Ref: TM-T6079
| 1mg | 52.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 167.00 € | ||
| 25mg | 301.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 791.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
NT157
CAS:1384426-12-3
NT157, a small tyrphostin, inhibits IRS, IGF-1R, and STAT3 in TME, reducing cancer cell survival.
Formula:
C16H14BrNO5S
Purity:
97.55%
Color and Shape:
Solid
Molecular weight:
412.26
Ref: TM-T4605
| 1mg | 54.00 € | ||
| 5mg | 125.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 361.00 € | ||
| 50mg | 569.00 € | ||
| 100mg | 807.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Ginsenoside Rg5
CAS:186763-78-0
Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.
Formula:
C42H70O12
Purity:
98% - 98.07%
Color and Shape:
Solid
Molecular weight:
767
Ref: TM-T6S1487
| 1mg | 112.00 € | ||
| 5mg | 259.00 € | ||
| 10mg | 420.00 € | ||
| 25mg | 689.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,296.00 € | ||
| 1mL*10mM (DMSO) | 358.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Linsitinib
CAS:867160-71-2
OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth …
Formula:
C26H23N5O
Purity:
98.98% - ≥95%
Color and Shape:
Solid
Molecular weight:
421.49
Ref: TM-T6017
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 162.00 € | ||
| 100mg | 217.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
AZD-3463
CAS:1356962-20-3
AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R …
Formula:
C24H25ClN6O
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
448.95
Ref: TM-T1967
| 5mg | 52.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 343.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
AG1024
CAS:65678-07-1
AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).
Formula:
C14H13BrN2O
Purity:
98% - 99.37%
Color and Shape:
Solid
Molecular weight:
305.17
Ref: TM-T2693
| 2mg | 41.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 233.00 € | ||
| 100mg | 351.00 € | ||
| 1mL*10mM (DMSO) | 64.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
AZ7550
CAS:1421373-99-0
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
Formula:
C27H31N7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
485.58
Ref: TM-T13564
| 1mg | 129.00 € | ||
| 5mg | 282.00 € | ||
| 10mg | 417.00 € | ||
| 25mg | 689.00 € | ||
| 50mg | 920.00 € | ||
| 100mg | 1,287.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
MAZ51
CAS:163655-37-6
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
Formula:
C21H18N2O
Purity:
98.53%
Color and Shape:
Solid
Molecular weight:
314.38
Ref: TM-T8496
| 1mg | 40.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 242.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | 599.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
XL228
CAS:898280-07-4
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM …
Formula:
C22H31N9O
Purity:
99.07%
Color and Shape:
Solid
Molecular weight:
437.54
Ref: TM-T17267
| 1mg | 55.00 € | ||
| 2mg | 77.00 € | ||
| 5mg | 97.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 569.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Ceritinib dihydrochloride
CAS:1380575-43-8
Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase …
Formula:
C28H38Cl3N5O3S
Purity:
99.99%
Color and Shape:
Solid
Molecular weight:
631.06
Ref: TM-T1791L
| 5mg | 50.00 € | ||
| 10mg | 63.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 122.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Ceritinib
CAS:1032900-25-6
Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor …
Formula:
C28H36ClN5O3S
Purity:
100% - 99.73%
Color and Shape:
Solid
Molecular weight:
558.14
Ref: TM-T1791
| 5mg | 49.00 € | ||
| 10mg | 68.00 € | ||
| 50mg | 88.00 € | ||
| 100mg | 131.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
BMS-754807
CAS:1001350-96-4
BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.
Formula:
C23H24FN9O
Purity:
98.86%
Color and Shape:
Solid
Molecular weight:
461.49
Ref: TM-T2349
| 1mg | 49.00 € | ||
| 2mg | 69.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 163.00 € | ||
| 25mg | 321.00 € | ||
| 50mg | 525.00 € | ||
| 100mg | 755.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
I-OMe-Tyrphostin AG 538
CAS:1094048-77-7
I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, …
Formula:
C17H12INO5
Purity:
96.66%
Color and Shape:
Solid
Molecular weight:
437.19
Ref: TM-T11593
| 1mg | 55.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 423.00 € | ||
| 50mg | 627.00 € | ||
| 100mg | 887.00 € | ||
| 500mg | 1,782.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Monday 3 Feb 2025
Tyrphostin AG 538
CAS:133550-18-2
Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for …
Formula:
C16H11NO5
Purity:
99.73%
Color and Shape:
Soild
Molecular weight:
297.26
Ref: TM-T67707
| 1mg | 96.00 € | ||
| 5mg | 229.00 € | ||
| 10mg | 344.00 € | ||
| 25mg | 604.00 € | ||
| 50mg | 825.00 € | ||
| 100mg | 1,091.00 € |
Estimated delivery in United States, on Tuesday 18 Feb 2025
