IGF-1R
IGF-1R inhibitors are compounds that specifically target and inhibit the Insulin-like Growth Factor 1 Receptor (IGF-1R), a receptor tyrosine kinase involved in cellular growth, development, and survival. IGF-1R signaling plays a significant role in cancer progression, making these inhibitors valuable in oncology research. At CymitQuimica, we offer IGF-1R inhibitors to support your research in cancer biology, endocrinology, and targeted therapy development.
Found 98 products of "IGF-1R"
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TLK19781
CAS:TLK19781 is an insulin receptor modulator.Formula:C33H24Cl2N4O13S4Purity:98%Color and Shape:SolidMolecular weight:883.73OI338
OI338 is an orally available, ultralong-acting insulin analogue.Formula:C260H403N65O84S6Color and Shape:SolidMolecular weight:5971.76Gastric Inhibitory Peptide (1-42) (porcine) TFA
Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.Formula:C225H342N60O66S·XCF3COOHColor and Shape:SolidMolecular weight:4975.55LDD39
LDD39, a PROTAC targeting the degradation of RET protein, effectively and persistently degrades total RET (tRET) protein in vivo and inhibits phosphorylated RET (pRET) signaling.Formula:C55H59F2N11O6Color and Shape:SolidMolecular weight:1008.12[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
CAS:Insulin Receptor (1142-1153) binds insulin, is a substrate for its kinase, and has research/medical potential.Formula:C72H110N19O33P3Purity:98%Color and Shape:SolidMolecular weight:1862.67IGF-I (24-41)
CAS:IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.
Formula:C88H133N27O28Purity:98%Color and Shape:SolidMolecular weight:2017.16[D-Ala2]-GIP (human)
CAS:Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.Formula:C226H338N60O66SPurity:98%Color and Shape:SolidMolecular weight:4983.58Teprotumumab
CAS:Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.
Purity:SDS-PAGE:95.2%;SEC-HPLC:99.6%Color and Shape:LiquidMolecular weight:145.62 kDacis-NVP-ADW742
CAS:NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.Formula:C28H31N5OColor and Shape:SolidMolecular weight:453.59DA-JC4
CAS:DA-JC4: dual GLP-1/GIP agonist, for neurological disease research and insulin pathway studies.Formula:C225H346N56O65Color and Shape:SolidMolecular weight:4875.49GIP, human
CAS:Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.
Formula:C226H338N60O66SPurity:98%Color and Shape:SolidMolecular weight:4983.6WAY-270250
CAS:WAY-270250 is an IGF-1R/SRC inhibitor.Formula:C18H16N2O2Purity:99.97%Color and Shape:SoildMolecular weight:292.33NBI-31772
CAS:NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).Formula:C17H11NO7Purity:99.79%Color and Shape:SolidMolecular weight:341.27GIP (1-30) amide,human
CAS:GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Formula:C162H240N40O47SPurity:98%Color and Shape:SolidMolecular weight:3531.94Macupatide
CAS:Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.Color and Shape:SolidZIGIR
ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.Formula:C39H40N6O3Purity:98.34% - 99.32%Color and Shape:SolidMolecular weight:640.77TAK-778
CAS:TAK-778, a derivative of ipriflavone, demonstrates the ability to stimulate bone growth in both in vitro and in vivo models.Formula:C24H28NO7PSPurity:98%Color and Shape:SolidMolecular weight:505.52Acetyl Gastric Inhibitory Peptide (human)
CAS:Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.Formula:C228H340N60O67SColor and Shape:SolidMolecular weight:5025.6IGF-1R inhibitor-2
CAS:IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.Formula:C24H24FN7O2Color and Shape:SolidMolecular weight:461.501(Pro3) GIP, human
CAS:(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.Formula:C226H338N60O64SColor and Shape:SolidMolecular weight:4951.53
![[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1259.webp&w=3840&q=75)
