Ubiquitination
Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.
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Subcategories of "Ubiquitination"
Products of "Ubiquitination"
MSC1094308
CAS:2219320-08-6
MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.
Formula:
C29H29F3N2
Color and Shape:
Solid
Molecular weight:
462.55
Ref: TM-T12114
| 2mg | 296.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
STD1T
CAS:893075-58-6
STD1T is a USP2a inhibitor with anticancer activity that reduces levels of the cell cycle …
Formula:
C19H19N3O4S2
Purity:
98.77%
Color and Shape:
Liquid
Molecular weight:
417.5
Ref: TM-T36970
| 1mg | 214.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
USP1-IN-2
CAS:2098212-05-4
USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.
Formula:
C26H22F4N6O
Purity:
99.60% - 99.88%
Color and Shape:
Liquid
Molecular weight:
510.486
Ref: TM-T63518
| 1mg | 276.00 € | ||
| 5mg | 679.00 € | ||
| 10mg | 868.00 € | ||
| 25mg | 1,320.00 € | ||
| 50mg | 1,712.00 € | ||
| 100mg | 2,340.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
USP8-IN-1
CAS:2477650-96-5
USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits …
Formula:
C18H21N5O3S
Purity:
98.01%
Color and Shape:
Soild
Molecular weight:
387.46
Ref: TM-T60146
| 1mg | 86.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 254.00 € | ||
| 25mg | 445.00 € | ||
| 50mg | 628.00 € | ||
| 100mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 198.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
BI8626
CAS:1875036-75-1
BI8626 is a ubiquitin ligase inhibitor with protective effects against spontaneous dry syndrome in NOD/ShiLtj …
Formula:
C25H28N8
Color and Shape:
Solid
Molecular weight:
440.54
Ref: TM-T14569
| 1mg | 91.00 € | ||
| 5mg | 186.00 € | ||
| 10mg | 294.00 € | ||
| 25mg | 495.00 € | ||
| 50mg | 705.00 € | ||
| 100mg | 925.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Thursday 19 Dec 2024
MID-1
CAS:312608-54-1
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.
Formula:
C12H11N3O4S
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
293.3
Ref: TM-T8773
| 1mg | 49.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 370.00 € | ||
| 100mg | 525.00 € | ||
| 200mg | 713.00 € | ||
| 1mL*10mM (DMSO) | 106.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
IU1
CAS:314245-33-5
IU1(IC50=4.7 μ M), a reversible, specific human USP14 proteasome inhibitor, can penetrate the cell.
Formula:
C18H21FN2O
Purity:
98% - 99.30%
Color and Shape:
Solid
Molecular weight:
300.37
Ref: TM-T6107
| 5mg | 59.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 234.00 € | ||
| 100mg | 416.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
P005091
CAS:882257-11-6
P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 …
Formula:
C12H7Cl2NO3S2
Purity:
99.53% - 99.87%
Color and Shape:
Solid
Molecular weight:
348.22
Ref: TM-T6925
| 2mg | 51.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 257.00 € | ||
| 100mg | 406.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
VLX1570
CAS:1431280-51-1
VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM …
Formula:
C23H17F2N3O6
Purity:
98.53% - 99.91%
Color and Shape:
Solid
Molecular weight:
469.39
Ref: TM-T4067
| 1mg | 94.00 € | ||
| 2mg | 151.00 € | ||
| 5mg | 255.00 € | ||
| 10mg | 398.00 € | ||
| 25mg | 668.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,277.00 € | ||
| 1mL*10mM (DMSO) | 264.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
ML-323
CAS:1572414-83-5
ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay and in orthogonal …
Formula:
C23H24N6
Purity:
99.87% - 99.96%
Color and Shape:
Solid
Molecular weight:
384.48
Ref: TM-T1757
| 5mg | 197.00 € | ||
| 10mg | 315.00 € | ||
| 25mg | 487.00 € | ||
| 50mg | 737.00 € | ||
| 100mg | 1,083.00 € | ||
| 1mL*10mM (DMSO) | 233.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
PR-619
CAS:2645-32-1
PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective …
Formula:
C7H5N5S2
Purity:
100% - 99.83%
Color and Shape:
Solid
Molecular weight:
223.28
Ref: TM-T1862
| 5mg | 49.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 90.00 € | ||
| 50mg | 109.00 € | ||
| 100mg | 153.00 € | ||
| 200mg | 223.00 € | ||
| 500mg | 365.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Nutlin-3
CAS:548472-68-0
Nutlin-3 is an MDM2 antagonist that inhibits MDM2-p53 interaction and activates p53. Nutlin-3 has antitumor …
Formula:
C30H30Cl2N4O4
Purity:
98.27% - 99.89%
Color and Shape:
Solid
Molecular weight:
581.49
Ref: TM-T2158
| 2mg | 58.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 243.00 € | ||
| 50mg | 450.00 € | ||
| 100mg | 485.00 € | ||
| 1mL*10mM (DMSO) | 109.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
DUB-IN-2
CAS:924296-19-5
Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.
Formula:
C15H9N5O
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
275.26
Ref: TM-T11111
| 1mg | 135.00 € | ||
| 2mg | 183.00 € | ||
| 5mg | 280.00 € | ||
| 10mg | 403.00 € | ||
| 25mg | 653.00 € | ||
| 50mg | 926.00 € | ||
| 100mg | 1,276.00 € | ||
| 1mL*10mM (DMSO) | 290.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
GNE-6640
CAS:2009273-67-8
GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 …
Formula:
C20H18N4O
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
330.38
Ref: TM-T5461
| 1mg | 70.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 151.00 € | ||
| 10mg | 247.00 € | ||
| 25mg | 528.00 € | ||
| 50mg | 762.00 € | ||
| 100mg | 1,060.00 € | ||
| 1mL*10mM (DMSO) | 164.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Indole-3-carbinol
CAS:700-06-1
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB …
Formula:
C9H9NO
Purity:
100% - 97.06%
Color and Shape:
Solid
Molecular weight:
147.17
Ref: TM-T2947
| 1g | 34.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
TCID
CAS:30675-13-9
TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has …
Formula:
C9H2Cl4O2
Purity:
97.16%
Color and Shape:
Solid
Molecular weight:
283.92
Ref: TM-T6697
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 171.00 € | ||
| 50mg | 216.00 € | ||
| 100mg | 279.00 € | ||
| 1mL*10mM (DMSO) | 61.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
DKM 2-93
CAS:65836-72-8
DKM 2-93 is a relatively selective inhibitor of UBA5(IC50 : 430 μM).
Formula:
C11H14ClNO3
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
243.69
Ref: TM-T7415
| 100mg | 47.00 € | ||
| 200mg | 75.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
Subasumstat
CAS:1858276-04-6
Subasumstat (TAK-981) is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic …
Formula:
C25H28ClN5O5S2
Purity:
97.02% - 98.22%
Color and Shape:
Solid
Molecular weight:
578.1
Ref: TM-T8428
| 1mg | 82.00 € | ||
| 2mg | 105.00 € | ||
| 5mg | 157.00 € | ||
| 10mg | 239.00 € | ||
| 25mg | 444.00 € | ||
| 50mg | 640.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
IU1-248
CAS:2307472-03-1
IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with …
Formula:
C20H23N3O2
Purity:
99.30%
Color and Shape:
Solid
Molecular weight:
337.42
Ref: TM-T9375
| 1mg | 76.00 € | ||
| 5mg | 167.00 € | ||
| 10mg | 261.00 € | ||
| 25mg | 528.00 € | ||
| 50mg | 744.00 € | ||
| 100mg | 1,060.00 € | ||
| 1mL*10mM (DMSO) | 178.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
GS143
CAS:916232-21-8
GS143 inhibits IκBα ubiquitination (IC50=5.2μM), suppresses NF-κB, and has anti-asthma properties without hindering proteasomes.
Formula:
C28H19FN2O4
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
466.46
Ref: TM-T25465
| 2mg | 37.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 250.00 € | ||
| 100mg | 364.00 € | ||
| 200mg | 528.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 23 Dec 2024
