Proteasome
Proteasome inhibitors are compounds that inhibit the proteasome, a large protein complex responsible for degrading unwanted or damaged proteins within the cell. Inhibition of the proteasome leads to the accumulation of proteins, which can induce cell cycle arrest and apoptosis, particularly in rapidly dividing cells like cancer cells. Proteasome inhibitors are crucial in cancer research and therapy, especially in the treatment of multiple myeloma and other hematologic malignancies. At CymitQuimica, we offer proteasome inhibitors to support your research in oncology, cell biology, and drug development.
Found 72 products for "Proteasome".
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Gabexate mesylate
CAS:Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.Formula:C17H27N3O7SPurity:99.2% - 99.64%Color and Shape:White CrystalMolecular weight:417.48UT-34
CAS:UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wildFormula:C15H12F4N4O2Purity:98.12%Color and Shape:SolidMolecular weight:356.275RAMB4
CAS:RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.Formula:C19H13Cl4NOPurity:98.89% - 99.38%Color and Shape:Yellow SolidMolecular weight:413.12RA190
CAS:RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.Formula:C28H23Cl5N2O2Purity:97.7%Color and Shape:SolidMolecular weight:596.759Arimoclomol maleate
CAS:Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formula:C18H24ClN3O7Purity:99.44% - 99.98%Color and Shape:SolidMolecular weight:429.852Pepstatin
CAS:Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formula:C34H63N5O9Purity:96.74% - 99.94%Color and Shape:SolidMolecular weight:685.8921ML604440
CAS:ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.Formula:C17H24BF3N2O4Purity:97.06%Color and Shape:SolidMolecular weight:388.19Protease Inhibitor Library
A unique collection of xnum protease and proteasome inhibitors for research in chemical genomics, and drug screening;Color and Shape:Odour SolidPhepropeptin B
CAS:Phepropeptin B is a secondary metabolite derived from microorganisms, functioning as a proteasome (proteasome) inhibitor with an IC50 value of 11 μg/mL.Formula:C40H56N6O6Color and Shape:SolidMolecular weight:716.91Phepropeptin C
CAS:Phepropeptin C is a microbial secondary metabolite that acts as a proteasome (proteasome) inhibitor, with an IC50 of 12.5 μg/mL.Formula:C38H60N6O6Color and Shape:SolidMolecular weight:696.92Z-Leu-Leu-Tyr-COCHO
CAS:Z-Leu-Leu-Tyr-COCHO is a potent inhibitor of chymotrypsin-like activity, exhibiting a Ki value of 3.0 nM [1].Formula:C30H39N3O7Purity:98%Color and Shape:SolidMolecular weight:553.65Dazcapistat
CAS:Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.Formula:C21H18FN3O4Purity:99.11%Color and Shape:SolidMolecular weight:395.3837Proteasome-IN-7
Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.Formula:C48H56N6O10SColor and Shape:SolidMolecular weight:909.06Iso-VQA-ACC acetate
Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.Color and Shape:Odour SolidBortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Color and Shape:Odour SolidLXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.Formula:C27H22FN7O6Purity:99.89%Color and Shape:SolidMolecular weight:559.51Ac-Nle-Pro-Nle-Asp-AMC
CAS:Ac-Nle-Pro-Nle-Asp-AMC: 26S proteasome substrate for caspase-like activity analysis.Formula:C33H45N5O9Molecular weight:655.7385Z-Gly-Pro-Phe-Leu-CHO
CAS:Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde serving as a selective and potent proteasome inhibitor, demonstrating inhibition constants (Ki) ofFormula:C30H38N4O6Purity:98%Color and Shape:SolidMolecular weight:550.65Suc-Leu-Leu-Val-Tyr-AMC
CAS:Suc-Leu-Leu-Val-Tyr-AMC is a fluorogenic tetrapeptide substrate for 20S proteasome and chymotrypsin-like proteases, used in drug screening.Formula:C40H53N5O10Purity:98%Color and Shape:SolidMolecular weight:763.8763Phepropeptin A
CAS:Phepropeptin A is a secondary metabolite produced by microorganisms and acts as a proteasome (proteasome) inhibitor, with an IC50 of 21 μg/mL.Formula:C37H58N6O6Color and Shape:SolidMolecular weight:682.89
