Ubiquitination
Ubiquitination inhibitors are compounds that interfere with the process of ubiquitination, where proteins are tagged with ubiquitin molecules for degradation by the proteasome. These inhibitors are critical for studying protein turnover, signal transduction, and the regulation of various cellular processes. Ubiquitination plays a key role in many diseases, including cancer, neurodegenerative disorders, and immune system dysfunction. By modulating ubiquitination, these inhibitors can provide insights into the mechanisms of disease and open up new avenues for therapeutic intervention. At CymitQuimica, we offer a wide selection of high-quality ubiquitination inhibitors to support your research in cell biology, proteomics, and drug discovery.
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Subcategories of "Ubiquitination"
Products of "Ubiquitination"
GNE-6776
CAS:2009273-71-4
GNE-6776 is a selective USP7 inhibitor.
Formula:
C20H20N4O2
Purity:
96.59% - 98.2%
Color and Shape:
Solid
Molecular weight:
348.4
Ref: TM-T4634
| 1mg | 80.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 268.00 € | ||
| 25mg | 513.00 € | ||
| 50mg | 736.00 € | ||
| 100mg | 1,014.00 € | ||
| 1mL*10mM (DMSO) | 186.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ICCB-19 hydrochloride
CAS:1803605-68-6
ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It …
Formula:
C12H22ClN3OS
Purity:
99.30%
Color and Shape:
Solid
Molecular weight:
291.84
Ref: TM-T8931L
| 5mg | 36.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 143.00 € | ||
| 100mg | 207.00 € | ||
| 200mg | 308.00 € | ||
| 500mg | 487.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pevonedistat
CAS:905579-51-3
Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).
Formula:
C21H25N5O4S
Purity:
95% - 99.92%
Color and Shape:
Solid
Molecular weight:
443.52
Ref: TM-T6332
| 1mg | 52.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 255.00 € | ||
| 50mg | 423.00 € | ||
| 100mg | 701.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
LANOSTEROL
CAS:79-63-0
Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are …
Formula:
C30H50O
Purity:
99.42% - 99.67%
Color and Shape:
Solid
Molecular weight:
426.72
Ref: TM-T4970
| 1mg | 57.00 € | ||
| 50mg | 404.00 € | ||
| 100mg | 597.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
HBX 41108
CAS:924296-39-9
HBX 41108: non-competitive, reversible USP7 inhibitor; IC50: 424nM; blocks USP7-p53 deubiquitination; IC50: 0.8μM.
Formula:
C13H3ClN4O
Purity:
95.63%
Color and Shape:
Solid
Molecular weight:
266.64
Ref: TM-T21527
| 1mg | 51.00 € | ||
| 2mg | 73.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 415.00 € | ||
| 50mg | 612.00 € | ||
| 100mg | 872.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CYM5442
CAS:1094042-01-9
CYM5442 is an S1P agonist, targeting to Sphingosine.
Formula:
C23H27N3O4
Purity:
96.65% - 97.57%
Color and Shape:
Solid
Molecular weight:
409.48
Ref: TM-T2026
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 247.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 613.00 € | ||
| 500mg | 1,273.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
EOAI3402143
CAS:1699750-95-2
EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.
Formula:
C25H28Cl2N4O3
Purity:
98.09%
Color and Shape:
Solid
Molecular weight:
503.42
Ref: TM-T11209
| 1mg | 66.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 436.00 € | ||
| 50mg | 701.00 € | ||
| 100mg | 1,039.00 € | ||
| 1mL*10mM (DMSO) | 157.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
USP7-IN-8
CAS:2009273-60-1
Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 …
Formula:
C21H21N3O2
Purity:
99.31%
Color and Shape:
Solid
Molecular weight:
347.41
Ref: TM-T9217
| 1mg | 46.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 273.00 € | ||
| 50mg | 397.00 € | ||
| 100mg | 543.00 € | ||
| 200mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 102.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SJB2-043
CAS:63388-44-3
SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).
Formula:
C17H9NO3
Purity:
98.44%
Color and Shape:
Solid
Molecular weight:
275.26
Ref: TM-T7678
| 5mg | 51.00 € | ||
| 10mg | 86.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 423.00 € | ||
| 200mg | 611.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
NSC632839
CAS:157654-67-6
NSC-632839 (Ubiquitin Isopeptidase Inhibitor II) is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 …
Formula:
C21H22ClNO
Purity:
99.74% - 99.87%
Color and Shape:
Solid
Molecular weight:
339.86
Ref: TM-T3951
| 5mg | 56.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 153.00 € | ||
| 50mg | 260.00 € | ||
| 100mg | 392.00 € | ||
| 500mg | 878.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ginkgolic Acid
CAS:22910-60-7
Ginkgolic Acid (Romanicardic acid) C15:1 represses curli genes and prophage genes in EHEC.
Formula:
C22H34O3
Purity:
98.69% - 99.72%
Color and Shape:
White Powder
Molecular weight:
346.5
Ref: TM-T6S2123
| 20mg | 97.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CB-5083
CAS:1542705-92-9
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
Formula:
C24H23N5O2
Purity:
100% - 99.92%
Color and Shape:
Solid
Molecular weight:
413.47
Ref: TM-T6796
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 135.00 € | ||
| 25mg | 291.00 € | ||
| 50mg | 458.00 € | ||
| 100mg | 671.00 € | ||
| 500mg | 1,411.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DUB-IN-1
CAS:924296-18-4
DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific …
Formula:
C20H11N5O
Purity:
97.11% - 98.5%
Color and Shape:
Solid
Molecular weight:
337.33
Ref: TM-T11110
| 1mg | 63.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 629.00 € | ||
| 200mg | 863.00 € | ||
| 1mL*10mM (DMSO) | 124.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
2-D08
CAS:144707-18-6
2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of …
Formula:
C15H10O5
Purity:
98.58%
Color and Shape:
Solid
Molecular weight:
270.24
Ref: TM-T7379
| 5mg | 56.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 500.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
DUB-IN-3
CAS:924296-17-3
DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 …
Formula:
C16H9N5O
Purity:
99.34%
Color and Shape:
Solid
Molecular weight:
287.28
Ref: TM-T11112
| 1mg | 134.00 € | ||
| 2mg | 185.00 € | ||
| 5mg | 319.00 € | ||
| 10mg | 455.00 € | ||
| 25mg | 730.00 € | ||
| 50mg | 1,012.00 € | ||
| 100mg | 1,380.00 € | ||
| 500mg | 2,739.00 € | ||
| 1mL*10mM (DMSO) | 339.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Siremadlin
CAS:1448867-41-1
Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.
Formula:
C26H24Cl2N6O4
Purity:
97.77% - 98.04%
Color and Shape:
Solid
Molecular weight:
555.41
Ref: TM-T5555
| 1mg | 66.00 € | ||
| 5mg | 128.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 336.00 € | ||
| 50mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 162.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
NMS-873
CAS:1418013-75-8
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
Formula:
C27H28N4O3S2
Purity:
99.05% - 99.5%
Color and Shape:
Solid
Molecular weight:
520.67
Ref: TM-T1853
| 2mg | 46.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 194.00 € | ||
| 50mg | 351.00 € | ||
| 100mg | 541.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
USP7/USP47 inhibitor
CAS:1247825-37-1
USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of …
Formula:
C18H11Cl2N3O3S3
Purity:
97.98% - 98.5%
Color and Shape:
Solid
Molecular weight:
484.4
Ref: TM-T4338
| 1mg | 43.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 159.00 € | ||
| 25mg | 328.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 899.00 € | ||
| 500mg | 1,772.00 € | ||
| 1mL*10mM (DMSO) | 98.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
ML240
CAS:1346527-98-7
ML240 is a selective, ATP-competitive p97 inhibitor.
Formula:
C23H20N6O
Purity:
100% - 99.66%
Color and Shape:
Solid
Molecular weight:
396.44
Ref: TM-T3535
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 401.00 € | ||
| 100mg | 593.00 € | ||
| 500mg | 1,267.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
XL177A
CAS:2417089-74-6
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing …
Formula:
C48H57ClN8O5
Purity:
98.75%
Color and Shape:
Solid
Molecular weight:
861.47
Ref: TM-T9122
| 1mg | 94.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 292.00 € | ||
| 25mg | 495.00 € | ||
| 50mg | 714.00 € | ||
| 100mg | 1,006.00 € | ||
| 1mL*10mM (DMSO) | 281.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
