Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1504 products of "Autophagy"
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NSC 33994
CAS:NSC 33994 is a selective inhibitor of JAK2 (IC50 = 60 nM). It also shows no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.Formula:C28H42N2O2Purity:98%Color and Shape:SolidMolecular weight:438.65SR 3677 dihydrochloride
CAS:Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).Formula:C22H26Cl2N4O4Color and Shape:SolidMolecular weight:481.37Lamotrigine isethionate
CAS:Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.Formula:C11H13Cl2N5O4SColor and Shape:SolidMolecular weight:382.22Evogliptin tartrate
CAS:Evogliptin tartrate: Oral DPP-4 inhibitor, may treat atherosclerosis and diabetes.Formula:C23H32F3N3O9Color and Shape:SolidMolecular weight:551.51PF-06371900
CAS:PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).Formula:C17H16N6O2SColor and Shape:SolidMolecular weight:368.41Ralimetinib
CAS:Ralimetinib blocks MK2 phosphorylation at Thr334 without affecting p38α MAPK or JNK. It is an ATP-competitive inhibitor of p38 MAPK α/β (IC50 5.3/3.2 nM).Formula:C24H29FN6Purity:99.16% - 99.21%Color and Shape:SolidMolecular weight:420.53CXCR4 antagonist 5
CAS:CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.Formula:C21H30N6Color and Shape:SolidMolecular weight:366.5Ivacaftor benzenesulfonate
CAS:Ivacaftor benzenesulfonate used for cystic fibrosis treatment. is an orally bioavailable CFTR potentiator.Formula:C30H34N2O6SPurity:98%Color and Shape:SolidMolecular weight:550.67PF-06455943
CAS:PF-06455943: LRRK2 inhibitor, IC50=3nM, PET radioligand, used for ADME/neuro PK & Parkinson's research.Formula:C17H14FN5OColor and Shape:SolidMolecular weight:323.32Dinoprost
CAS:Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formula:C20H34O5Purity:97.94% - 98.04%Color and Shape:White To Off-White Crystalline SolidMolecular weight:354.48Ref: TM-T15133
5mg49.00€10mg74.00€25mg137.00€50mg205.00€100mg326.00€200mg485.00€1mL*10mM (DMSO)54.00€Ivacaftor hydrate
CAS:Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.Formula:C24H30N2O4Purity:98%Color and Shape:SolidMolecular weight:410.514Poloppin
CAS:Poloppin modulates polo-like kinases, targets mutant KRAS, and enhances Crizotinib's effects against KRAS-mutant cancers.Formula:C20H15BrF3NO2Purity:98%Color and Shape:SolidMolecular weight:438.24Amsacrine
CAS:Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.Formula:C21H19N3O3SPurity:99.2% - 99.34%Color and Shape:Yellow Crystalline Powder SolidMolecular weight:393.46CUR5g
CAS:CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.Formula:C22H20N2O2Purity:98.92%Color and Shape:SolidMolecular weight:344.41Ref: TM-T73550
1mg58.00€5mg128.00€10mg197.00€25mg394.00€50mg627.00€100mg928.00€1mL*10mM (DMSO)141.00€p38 MAPK-IN-2
CAS:p38 MAPK-IN-2 is an inhibitor of p38 kinase.Formula:C20H19ClFN5O2Purity:98%Color and Shape:SolidMolecular weight:415.85(3S,5R)-Rosuvastatin
CAS:(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).Formula:C22H28FN3O6SPurity:98%Color and Shape:SolidMolecular weight:481.54ACT-660602
CAS:ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.Formula:C20H20F6N8OSColor and Shape:SolidMolecular weight:534.48BC-1485
CAS:BC-1485 is a small molecule inhibitor of FIEL1 that inhibits the degradation of PIAS4 and ameliorates fibrosis in a mouse model.Formula:C19H21N5O5SPurity:97.03% - 97.15%Color and Shape:SolidMolecular weight:431.473HOI-BA-01
CAS:3HOI-BA-01 is a mammalian targeting effective rapamycin activation inhibitor.Formula:C19H15NO5Purity:98%Color and Shape:SolidMolecular weight:337.33DK-1-49
CAS:DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.Formula:C28H31N5O3S2Purity:98%Color and Shape:SolidMolecular weight:549.71LRRK2-IN-10
CAS:LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2Formula:C20H15N5OPurity:98%Color and Shape:SolidMolecular weight:341.37MF-095
CAS:MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.Formula:C27H31N3O4SColor and Shape:SolidMolecular weight:493.62FAAH-IN-1
CAS:FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.Formula:C20H19ClN4OSPurity:98%Color and Shape:SolidMolecular weight:398.91Momelotinib Mesylate
CAS:Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.Formula:C24H26N6O5SPurity:98%Color and Shape:SolidMolecular weight:510.57SB02024
CAS:SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.Formula:C16H22F3N3O2Color and Shape:SolidMolecular weight:345.36Metofenazate
CAS:Metofenazate is an selective inhibitor of calmodulin .Formula:C31H36ClN3O5SPurity:98%Color and Shape:SolidMolecular weight:598.15GSK3-IN-3
CAS:GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.
Formula:C24H35N3O4Purity:99.37%Color and Shape:SolidMolecular weight:429.55HF50731
CAS:HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).Formula:C26H46N4Color and Shape:SolidMolecular weight:414.67LV-320
CAS:LV-320, potent ATG4B inhibitor; IC50: 24.5 μM, Kd: 16 μM. Blocks autophagy, stable, non-toxic, active in vivo. Useful for ATG4B research in cancer.Formula:C29H26ClNO2S2Purity:98%Color and Shape:SolidMolecular weight:520.11SA 47
CAS:SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.Formula:C17H26N4O3Purity:98%Color and Shape:SolidMolecular weight:334.41Rimacalib
CAS:Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).Formula:C22H23FN4O2Purity:98%Color and Shape:SolidMolecular weight:394.44SR-17398
CAS:SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM).Formula:C14H18N4OPurity:98%Color and Shape:SolidMolecular weight:258.32ABTL-0812
CAS:ABTL-0812 induces endoplasmic reticulum (ER) stress-mediated autophagy, and with anti-cancer activity.Formula:C18H32O3Color and Shape:SolidMolecular weight:296.44FR 167653 free base
CAS:FR 167653 is an oral p38 MAPK inhibitor for inflammation, trauma, ischemia relief; it suppresses TNF-α, IL-1β.Formula:C24H18FN5O2Purity:98%Color and Shape:SolidMolecular weight:427.43ROC-325
CAS:ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.Formula:C28H27ClN4OSPurity:99.26%Color and Shape:SolidMolecular weight:503.06AMDE-1
CAS:AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.Formula:C18H8ClF6N3Purity:90%Color and Shape:SolidMolecular weight:415.72AGN 205728
CAS:AGN 205728 is a potent and selective RARγ antagonist (Ki: 3 nM; IC95: 0.6 nM) and has no inhibition on RARα and RARβ.Formula:C29H27NO3Purity:98%Color and Shape:SolidMolecular weight:437.53CCT128930
CAS:'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'Formula:C18H20ClN5Purity:99.07% - 99.18%Color and Shape:SolidMolecular weight:341.84Ref: TM-T6303
2mg39.00€5mg62.00€10mg88.00€25mg166.00€50mg259.00€100mg388.00€200mg617.00€1mL*10mM (DMSO)67.00€Autophagy inducer 3
CAS:Autophagy Inducer 3 triggers selective cancer cell death via autophagy, sparing healthy cells.Formula:C24H43NO2Color and Shape:SolidMolecular weight:377.6SRT3190
CAS:SRT3190 is an antagonist of CXCR2.Formula:C18H23F2N5O4S2Purity:98%Color and Shape:SolidMolecular weight:475.53SCH 546738
CAS:SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.Formula:C23H31Cl2N7OPurity:98.67%Color and Shape:SolidMolecular weight:492.45K67
CAS:K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.Formula:C29H30N2O7S2Purity:98.43%Color and Shape:SolidMolecular weight:582.69(-)-Talarozole
CAS:(-)-Talarozole is a potent retinoic acid metabolism inhibitor.Formula:C21H23N5SColor and Shape:SolidMolecular weight:377.51AZ10397767
CAS:AZ10397767: Potent CXCR2 blocker (IC50=1nM); lowers neutrophil infiltration in tumors in vitro/in vivo.Formula:C15H14ClFN4O2S2Color and Shape:SolidMolecular weight:400.88PS372424
CAS:PS372424 is a specific agonist of human CXCR3, with anti-inflammatory activity.Formula:C33H44N6O4Purity:98%Color and Shape:SolidMolecular weight:588.74MDK-6983
CAS:MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.Formula:C22H18Cl2N2O3Purity:99.68%Color and Shape:SolidMolecular weight:429.3Ref: TM-T28001
1mg115.00€5mg249.00€10mg368.00€25mg562.00€50mg787.00€100mg1,054.00€500mgTo inquire1mL*10mM (DMSO)284.00€(Rac)-AZD 6482
CAS:(Rac)-AZD 6482 is the racemate of AZD 6482. AZD 6482 is a potent and selective inhibitor of p110β (IC50 of 0.69 nM).Formula:C22H24N4O4Color and Shape:SolidMolecular weight:408.45LRRK2-IN-7
CAS:LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.Formula:C24H26N6OPurity:99.26%Color and Shape:SolidMolecular weight:414.5CCT020312
CAS:CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.Formula:C31H30Br2N4O2Purity:98.63%Color and Shape:SolidMolecular weight:650.4Ref: TM-T14902
1mg58.00€5mg133.00€10mg227.00€25mg386.00€50mg572.00€100mg795.00€500mg1,648.00€1mL*10mM (DMSO)178.00€AMG PERK 44
CAS:AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.Formula:C34H29ClN4O2Purity:98.8% - 99.81%Color and Shape:SolidMolecular weight:561.07XRK3F2
CAS:XRK3F2 inhibits p62-ZZ, counters MM's Runx2 suppression in vitro, and prompts bone growth and remodeling in vivo with tumors.Formula:C23H24ClF2NO3Purity:98.91% - 99.12%Color and Shape:SolidMolecular weight:435.89MAPK13-IN-1
CAS:MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).Formula:C20H23N5O2Purity:99.62%Color and Shape:SolidMolecular weight:365.43Ref: TM-T11943
1mg94.00€2mg137.00€5mg222.00€10mg334.00€25mg578.00€50mg838.00€100mg1,224.00€500mg2,448.00€1mL*10mM (DMSO)245.00€ITX5061
CAS:ITX5061 is a type II inhibitor of p38 MAPK and scavenger receptor B1 (SRB1) antagonist for the study of hepatitis C virus infection.Formula:C30H38ClN3O7SPurity:98.35%Color and Shape:SolidMolecular weight:620.16Ref: TM-T15603
1mg192.00€5mg485.00€10mg713.00€25mg1,198.00€50mg1,693.00€100mg2,250.00€1mL*10mM (DMSO)642.00€Mavorixafor
CAS:Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding.Formula:C21H27N5Purity:98.56%Color and Shape:SolidMolecular weight:349.47Ref: TM-TQ0174
1mg39.00€2mg50.00€5mg84.00€10mg123.00€25mg215.00€50mg348.00€100mg557.00€1mL*10mM (DMSO)92.00€Ezurpimtrostat hydrochloride
CAS:Ethacrysta hydrochloride (GNS561 hydrochloride) is a PPT1 inhibitor with antifibrotic properties and may be used in studies of hepatocellular carcinoma.Formula:C25H32Cl2N4Purity:99.84%Color and Shape:SolidMolecular weight:459.45NUCC-390
CAS:NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically to AMD3100.Formula:C23H33N5OPurity:97.08%Color and Shape:SolidMolecular weight:395.54Ref: TM-T12269
1mg109.00€5mg260.00€10mg409.00€25mg730.00€50mg1,018.00€100mg1,369.00€200mg1,783.00€1mL*10mM (DMSO)268.00€Acetazolamide sodium
CAS:Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.Formula:C4H5N4NaO3S2Purity:99.71% - 99.87%Color and Shape:SolidMolecular weight:244.23Elubrixin
CAS:Elubrixin (SB-656933) inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM).Formula:C17H17Cl2FN4O4SPurity:98.65% - 99.78%Color and Shape:SolidMolecular weight:463.31Ref: TM-T11179
1mg109.00€5mg235.00€10mg349.00€25mg532.00€50mg745.00€100mg999.00€200mg1,333.00€1mL*10mM (DMSO)253.00€Dactolisib Tosylate
CAS:Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor that targets PI3K and mTOR.Formula:C37H31N5O4SPurity:99.91%Color and Shape:SolidMolecular weight:641.74Apostatin-1
CAS:Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Formula:C19H27N3OSPurity:99.31%Color and Shape:SolidMolecular weight:345.5Ref: TM-T9079
1mg34.00€2mg49.00€5mg74.00€10mg113.00€25mg222.00€50mg358.00€100mg530.00€500mg1,153.00€1mL*10mM (DMSO)82.00€Atg4B-IN-2
CAS:Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.Formula:C21H30O3Purity:98.86%Color and Shape:SolidMolecular weight:330.46Laduviglusib trihydrochloride
CAS:Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.Formula:C22H20Cl5N8Purity:99.34%Color and Shape:SolidMolecular weight:573.71FMK 9a
CAS:FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.Formula:C23H21FN2O3Purity:98.97%Color and Shape:SolidMolecular weight:392.42Ref: TM-T15303
1mg105.00€5mg260.00€10mg385.00€25mg620.00€50mg879.00€100mg1,153.00€200mg1,584.00€1mL*10mM (DMSO)269.00€Nilotinib hydrochloride
CAS:Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.Formula:C28H23ClF3N7OPurity:99.98%Color and Shape:SolidMolecular weight:565.98CP-312
CAS:CP-312 activates antioxidant defense, induces HMOX1, and shields human iPSC-derived cardiomyocytes from oxidative stress.Formula:C16H12ClN3OS2Purity:99.89%Color and Shape:SolidMolecular weight:361.87Cysmethynil
CAS:Cysmethynil is an indole-based Icmt inhibitor with antitumor activity, induces cell cycle arrest in G1 phase, and can be used for the study of solid tumors.Formula:C25H32N2OPurity:99%Color and Shape:SolidMolecular weight:376.53Ref: TM-T36082
1mg44.00€2mg57.00€5mg93.00€10mg133.00€25mg260.00€50mg416.00€100mg670.00€500mg1,341.00€Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formula:C45H60Cl2O6Purity:99.53% - 99.78%Color and Shape:SolidMolecular weight:767.86Tin-protoporphyrin IX dichloride
CAS:Tin-protoporphyrin IX inhibits HO-1, enhancing chemo efficacy in mouse PDAC.Formula:C34H32Cl2N4O4SnPurity:98%Color and Shape:SolidMolecular weight:750.26CHIR-99021 HCl
CAS:CHIR-99021 HCl is a selective GSK-3α/β inhibitor (IC50: 10/6.7 nM), 500x selective over other kinases, boosts Wnt pathway, and enhances stem cell renewal.Formula:C22H19Cl3N8Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:501.8Ref: TM-T2310L
1mg34.00€2mg49.00€5mg73.00€10mg90.00€25mg155.00€50mg227.00€100mg442.00€200mg640.00€500mg973.00€1mL*10mM (DMSO)81.00€IT1t dihydrochloride
CAS:IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4.Formula:C21H36Cl2N4S2Purity:99.91%Color and Shape:SolidMolecular weight:479.57Ref: TM-T11693L
2mg34.00€5mg50.00€10mg92.00€25mg166.00€50mg289.00€100mg420.00€200mg583.00€1mL*10mM (DMSO)56.00€Rosolutamide
CAS:Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.Formula:C28H32O6Purity:95.48% - 99.15%Color and Shape:SolidMolecular weight:464.55Cytarabine hydrochloride
CAS:Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase.
Formula:C9H14ClN3O5Purity:98.46%Color and Shape:White PowderMolecular weight:279.68MTK458
CAS:MTK458 (EP-0035985) is a PINK1 activator with antidepressant activity for the study of Parkinson;s disease.Formula:C17H15F3N4Purity:98.36%Color and Shape:SolidMolecular weight:332.32AC-73
CAS:AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.Formula:C21H21NO2Purity:99.36%Color and Shape:SolidMolecular weight:319.4Ref: TM-T14091
1mg50.00€5mg92.00€10mg170.00€25mg289.00€50mg487.00€100mg862.00€500mg1,728.00€1mL*10mM (DMSO)103.00€AZD8797
CAS:AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.Formula:C19H25N5OS2Purity:98.73% - 99.68%Color and Shape:SolidMolecular weight:403.56Ref: TM-T14384
1mg80.00€5mg170.00€10mg253.00€25mg442.00€50mg620.00€100mg845.00€1mL*10mM (DMSO)187.00€GC7 Sulfate
CAS:GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.Formula:C8H22N4O4SPurity:98.07% - 99.85%Color and Shape:SolidMolecular weight:270.35AZD8309
CAS:AZD8309 is an oral CXCR2 antagonist, curbing neutrophil movement, lowering MPO in lungs/pancreas, and trypsin/elastase activity.
Formula:C15H14F2N4O2S2Purity:98.35% - 99.67%Color and Shape:SolidMolecular weight:384.42Acitretin sodium
CAS:Acitretin sodium is a second-generation, systemic retinoid. It is also has been used in the treatment of psoriasis.Formula:C21H26NaO3Purity:98%Color and Shape:SolidMolecular weight:349.42SLLN-15
CAS:SLLN-15: oral, potent autophagy enhancer; targets macroautophagy in TNBC.Formula:C19H23N7Se2Purity:98%Color and Shape:SolidMolecular weight:507.35Di-N-desethyl amiodarone hydrochloride
CAS:Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].Formula:C21H22ClI2NO3Purity:98%Color and Shape:SolidMolecular weight:625.67SR10067
CAS:SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbβ(IC50 = 160 nM) and Rev-Erbα(IC50 = 170 nM) with anxiolytic activity.Formula:C31H31NO3Purity:99.57%Color and Shape:SolidMolecular weight:465.58Ref: TM-T12998
1mg46.00€5mg84.00€10mg114.00€25mg234.00€50mg348.00€100mg510.00€200mg858.00€1mL*10mM (DMSO)93.00€TIQ-15
CAS:TIQ-15 is an effective and selective CXCR4 antagonist. It has good drug-like properties.Formula:C23H32N4Purity:98%Color and Shape:SolidMolecular weight:364.53Antitumor agent-82
Antitumor agent-82: potent, anti-proliferative, induces autophagy via ATG5/ATG7.Formula:C32H42N6Color and Shape:SolidMolecular weight:510.72Calmidazolium chloride
CAS:Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.Formula:C31H23Cl7N2OPurity:98.53%Color and Shape:SolidMolecular weight:687.7Ref: TM-T10667
5mg59.00€10mg93.00€25mg138.00€50mg203.00€100mg304.00€200mg442.00€1mL*10mM (DMSO)90.00€4E2RCat
CAS:4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expressionFormula:C22H14ClNO4S2Purity:98.44%Color and Shape:SolidMolecular weight:455.93RK-682
CAS:RK-682 is a natural selective inhibitor of protein tyrosine phosphatases (PTPases).Formula:C21H36O5Color and Shape:SolidMolecular weight:368.51Beclin1-ATG14L interaction inhibitor 1
CAS:Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L.Formula:C23H24N4O5SPurity:98%Color and Shape:SolidMolecular weight:468.53LY2955303
CAS:LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM).Formula:C36H42N4O3Purity:98.56% - 99.85%Color and Shape:SolidMolecular weight:578.74AMD-3329 hydrobromide
CAS:AMD-3329 hydrobromide: strong, selective anti-HIV agent, blocks virus replication by targeting CXCR4 co-receptor.Formula:C34H58Br8N8Color and Shape:SolidMolecular weight:1218.13Butylate
CAS:Butylate is a herbicide of thiocarbamate.Formula:C11H23NOSColor and Shape:Less Liquid Which Darkens Upon Exposure To Light Air And Moisture Colorless Liquid Which Darkens Upon Exposure To Light Air And MoistureMolecular weight:217.37USP30 inhibitor 18
CAS:USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM). USP30 inhibitor 18 is able to accelerate mitophagy and increase protein ubiquitination.Formula:C26H28FN3O4SPurity:99.85%Color and Shape:SolidMolecular weight:497.58Ref: TM-T36682
1mg137.00€5mg281.00€10mg447.00€25mg713.00€50mg1,018.00€100mg1,369.00€500mg2,673.00€1mL*10mM (DMSO)309.00€E6130
CAS:E6130 may be effective in the treatment of inflammatory bowel disease and is a highly selective CX3CR1 regulator for oral administration.Formula:C28H37ClF3N3O3Color and Shape:SolidMolecular weight:556.06BPO-27 racemate
CAS:BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formula:C26H18BrN3O6Purity:97.67% - 98.86%Color and Shape:SolidMolecular weight:548.34Ref: TM-T10591
1mg44.00€5mg111.00€10mg166.00€25mg265.00€50mg388.00€100mg535.00€200mg718.00€1mL*10mM (DMSO)128.00€DCAP
CAS:DCAP, a broad-spectrum antibiotic, disrupts the membranes of both Gram-positive and Gram-negative bacteria. Additionally, it inhibits late-stage autophagy by blocking autophagolysosome maturation and interrupting autophagic flux [1].Formula:C19H22Cl2N2O4Color and Shape:SolidMolecular weight:413.3KN-93 Phosphate
CAS:KN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase.Cost-effective and quality-assured.Formula:C26H32ClN2O8PSPurity:99.58% - 99.93%Color and Shape:SolidMolecular weight:599.03Ref: TM-T2606
1mg49.00€5mg92.00€10mg137.00€25mg268.00€50mg497.00€100mg718.00€500mg1,431.00€1mL*10mM (DMSO)132.00€Ladarixin Sodium
CAS:Ladarixin Sodium, an Chemokine CXCR antagonist, is used potentially for the treatment of type I diabetes.Formula:C11H12F3NNaO6S2Color and Shape:SolidMolecular weight:398.32EACC
CAS:EACC inhibits Stx17, blocking autophagosome-lysosome fusion, and is a reversible autophagy inhibitor.Formula:C13H11N3O6S2Purity:99.8%Color and Shape:SolidMolecular weight:369.37INT-767
CAS:INT-767 is a highly potent farneson X receptor (FXR)/TGR5 dual agonist that prevents NASH and promotes visceral fat brown lipogenesis and mitochondrial functionFormula:C25H43NaO6SPurity:98%Color and Shape:SolidMolecular weight:494.66(3R,5R)-Rosuvastatin
CAS:(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).Formula:C22H28FN3O6SPurity:98%Color and Shape:SolidMolecular weight:481.54
