Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Adezmapimod
CAS:152121-47-6
Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive.
Formula:
C21H16FN3OS
Purity:
99.42% - 99.87%
Color and Shape:
White Solid
Molecular weight:
377.43
Ref: TM-T1764
| 5mg | 35.00 € | ||
| 10mg | 51.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 97.00 € | ||
| 200mg | 167.00 € | ||
| 500mg | 272.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Butein
CAS:487-52-5
Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.
Formula:
C15H12O5
Purity:
100% - 99.85%
Color and Shape:
Solid
Molecular weight:
272.25
Ref: TM-T6427
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 540.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
GW 501516
CAS:317318-70-0
GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with …
Formula:
C21H18F3NO3S2
Purity:
98.91% - 99.64%
Color and Shape:
White Solid
Molecular weight:
453.5
Ref: TM-T6151
| 5mg | 50.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 147.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Gambogic Acid
CAS:2752-65-0
Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases.
Formula:
C38H44O8
Purity:
97.16% - 98.67%
Color and Shape:
Solid
Molecular weight:
628.75
Ref: TM-T6185
| 2mg | 39.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 109.00 € | ||
| 50mg | 157.00 € | ||
| 100mg | 222.00 € | ||
| 500mg | 545.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Ruxolitinib phosphate
CAS:1092939-17-7
Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective …
Formula:
C17H21N6O4P
Purity:
100% - 99.91%
Color and Shape:
Solid
Molecular weight:
404.36
Ref: TM-T3043
| 1g | 604.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 64.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 144.00 € | ||
| 200mg | 223.00 € | ||
| 500mg | 408.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Perifosine
CAS:157716-52-4
Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.
Formula:
C25H52NO4P
Purity:
100% - 99.94%
Color and Shape:
Solid
Molecular weight:
461.66
Ref: TM-T2492
| 2mg | 46.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 158.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 435.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
GANT 61
CAS:500579-04-4
GANT 61 (GANT61) is an inhibitor for Gli1 and Gli2.
Formula:
C27H35N5
Purity:
100% - ≥95%
Color and Shape:
Solid
Molecular weight:
429.6
Ref: TM-T3070
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 300.00 € | ||
| 100mg | 421.00 € | ||
| 500mg | 975.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
UVI 3003
CAS:847239-17-2
UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.
Formula:
C28H36O4
Purity:
99.94%
Color and Shape:
Solid
Molecular weight:
436.58
Ref: TM-T17209
| 1mg | 35.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 398.00 € | ||
| 100mg | 594.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Dansylcadaverine
CAS:10121-91-2
Dansylcadaverine (Monodansyl cadaverine) is a fluorescent probe.
Formula:
C17H25N3O2S
Purity:
98.33% - 98.99%
Color and Shape:
Solid
Molecular weight:
335.46
Ref: TM-T18968
| 50mg | 34.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Pemetrexed disodium hemipenta hydrate
CAS:357166-30-4
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, …
Formula:
C20H21N5O6·2NaH2O
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
518.43
Ref: TM-T6226
| 50mg | 44.00 € | ||
| 100mg | 56.00 € | ||
| 200mg | 78.00 € | ||
| 500mg | 118.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SD 0006
CAS:271576-80-8
SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the …
Formula:
C20H20ClN5O2
Purity:
98.32%
Color and Shape:
Solid
Molecular weight:
397.86
Ref: TM-T7276
| 2mg | 37.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 142.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 328.00 € | ||
| 200mg | 459.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
BAR502
CAS:1612191-86-2
BAR502 is a dual GPBAR1 and FXR agonist (IC50s: 0.4 μM and 2 μM).
Formula:
C25H44O3
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
392.62
Ref: TM-TQ0252
| 1mg | 68.00 € | ||
| 5mg | 177.00 € | ||
| 10mg | 269.00 € | ||
| 25mg | 430.00 € | ||
| 50mg | 598.00 € | ||
| 100mg | 813.00 € | ||
| 200mg | 1,089.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Atezolizumab
CAS:1380723-44-3
Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has …
Purity:
95.10% - 95.20%
Color and Shape:
Liquid
Molecular weight:
145 kDa
Ref: TM-T9902
| 1mg | 213.00 € | ||
| 5mg | 505.00 € | ||
| 10mg | 741.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Dacinostat
CAS:404951-53-7
LAQ824 (Dacinostat (NVP-LAQ824)) is a novel HDAC inhibitor with IC50 of 32 nM and is …
Formula:
C22H25N3O3
Purity:
95.28% - 95.28%
Color and Shape:
Solid
Molecular weight:
379.45
Ref: TM-T2454
| 1mg | 49.00 € | ||
| 2mg | 67.00 € | ||
| 5mg | 108.00 € | ||
| 10mg | 177.00 € | ||
| 25mg | 315.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 690.00 € | ||
| 500mg | 1,420.00 € | ||
| 1mL*10mM (DMSO) | 110.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Guggulsterone
CAS:95975-55-6
Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.
Formula:
C21H28O2
Purity:
99.40%
Color and Shape:
Light Yellow Powder
Molecular weight:
312.45
Ref: TM-T5574
| 1mg | 35.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 198.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 399.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SR-18292
CAS:2095432-55-4
SR-18292 inhibits PGC-1α, enhances acetylation, lowers gluconeogenesis, and cuts hepatic glucose production.
Formula:
C23H30N2O2
Purity:
99% - 99.36%
Color and Shape:
Solid
Molecular weight:
366.5
Ref: TM-T4353
| 2mg | 40.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 278.00 € | ||
| 100mg | 439.00 € | ||
| 500mg | 917.00 € | ||
| 1mL*10mM (DMSO) | 71.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SB 242235
CAS:193746-75-7
SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an …
Formula:
C19H20FN5O
Purity:
99.13% - 99.68%
Color and Shape:
Solid
Molecular weight:
353.39
Ref: TM-T4078
| 2mg | 47.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 531.00 € | ||
| 1mL*10mM (DMSO) | 82.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Temsirolimus
CAS:162635-04-3
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment …
Formula:
C56H87NO16
Purity:
100% - 99.64%
Color and Shape:
White Crystalline Powder
Molecular weight:
1030.29
Ref: TM-T2145
| 2mg | 45.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 472.00 € | ||
| 500mg | 1,049.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
GSK4112
CAS:1216744-19-2
GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small …
Formula:
C18H21ClN2O4S
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
396.89
Ref: TM-T5045
| 10mg | 49.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 169.00 € | ||
| 100mg | 293.00 € | ||
| 200mg | 421.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
CA77.1
CAS:2412270-22-3
CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).
Formula:
C16H12ClN3O
Purity:
98.85%
Color and Shape:
Solid
Molecular weight:
297.74
Ref: TM-T9062
| 5mg | 57.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 161.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 380.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
