Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
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Pennogenin 3-O-β-chacotrioside
CAS:55916-52-4
Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.
Formula:
C45H72O17
Purity:
99.69% - 99.77%
Color and Shape:
Solid
Molecular weight:
885.04
Ref: TM-T8166
| 1mg | 65.00 € | ||
| 5mg | 126.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 319.00 € | ||
| 50mg | 467.00 € | ||
| 100mg | 693.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
RITA
CAS:213261-59-7
RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.
Formula:
C14H12O3S2
Purity:
97.76% - 98.85%
Color and Shape:
Solid
Molecular weight:
292.37
Ref: TM-T1798
| 1mg | 35.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 338.00 € | ||
| 100mg | 497.00 € | ||
| 200mg | 699.00 € | ||
| 500mg | 1,067.00 € | ||
| 1mL*10mM (DMSO) | 90.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
4EGI-1
CAS:315706-13-9
4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).
Formula:
C18H12Cl2N4O4S
Purity:
96.8% - 99.12%
Color and Shape:
Solid
Molecular weight:
451.28
Ref: TM-T2665
| 1mg | 43.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 215.00 € | ||
| 50mg | 344.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Bortezomib
CAS:179324-69-7
Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.
Formula:
C19H25BN4O4
Purity:
100% - 99.97%
Color and Shape:
Yellow Solid
Molecular weight:
384.24
Ref: TM-T2399
| 5mg | 50.00 € | ||
| 10mg | 61.00 € | ||
| 25mg | 76.00 € | ||
| 50mg | 92.00 € | ||
| 100mg | 138.00 € | ||
| 200mg | 214.00 € | ||
| 500mg | 354.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
CZC-25146 hydrochloride
CAS:1330003-04-7
CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type …
Formula:
C22H26ClFN6O4S
Purity:
99.06%
Color and Shape:
Solid
Molecular weight:
525
Ref: TM-T5139
| 1mg | 35.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 181.00 € | ||
| 50mg | 270.00 € | ||
| 100mg | 394.00 € | ||
| 200mg | 547.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Danshensu
CAS:76822-21-4
Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular …
Formula:
C9H10O5
Purity:
98.4% - 99.74%
Color and Shape:
Solid
Molecular weight:
198.17
Ref: TM-T3227
| 5mg | 36.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 103.00 € | ||
| 100mg | 157.00 € | ||
| 500mg | 355.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
SKF-96365 hydrochloride
CAS:130495-35-1
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest …
Formula:
C22H27ClN2O3
Purity:
99.48% - 99.85%
Color and Shape:
Solid
Molecular weight:
402.91
Ref: TM-T2170
| 5mg | 57.00 € | ||
| 10mg | 84.00 € | ||
| 25mg | 136.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 460.00 € | ||
| 200mg | 701.00 € | ||
| 500mg | 1,086.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Vitexin
CAS:3681-93-4
Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.
Formula:
C21H20O10
Purity:
99.16% - 99.64%
Color and Shape:
Yellow Powder
Molecular weight:
432.38
Ref: TM-T6S1369
| 5mg | 36.00 € | ||
| 10mg | 55.00 € | ||
| 25mg | 107.00 € | ||
| 50mg | 173.00 € | ||
| 100mg | 287.00 € | ||
| 1mL*10mM (DMSO) | 41.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
10074-G5
CAS:413611-93-5
10074-G5 is an inhibitor of c-Myc-Max dimerization.
Formula:
C18H12N4O3
Purity:
97.22% - 99.67%
Color and Shape:
Solid
Molecular weight:
332.31
Ref: TM-T3686
| 2mg | 46.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 87.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 223.00 € | ||
| 100mg | 392.00 € | ||
| 200mg | 558.00 € | ||
| 500mg | 880.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
KN-93
CAS:139298-40-1
KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to …
Formula:
C26H29ClN2O4S
Purity:
99.78% - 99.86%
Color and Shape:
White Solid
Molecular weight:
501.04
Ref: TM-T2697
| 1mg | 56.00 € | ||
| 2mg | 78.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 152.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 371.00 € | ||
| 100mg | 543.00 € | ||
| 1mL*10mM (DMSO) | 126.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Taxifolin
CAS:480-18-2
Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus …
Formula:
C15H12O7
Purity:
94.91% - 98.9%
Color and Shape:
Yellowish Powder
Molecular weight:
304.25
Ref: TM-T1738
| 25mg | 35.00 € | ||
| 50mg | 52.00 € | ||
| 100mg | 72.00 € | ||
| 500mg | 156.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
RAF265
CAS:927880-90-8
RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 …
Formula:
C24H16F6N6O
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
518.41
Ref: TM-T6296
| 1mg | 46.00 € | ||
| 2mg | 62.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 261.00 € | ||
| 50mg | 425.00 € | ||
| 100mg | 625.00 € | ||
| 1mL*10mM (DMSO) | 99.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
D-glutamine
CAS:5959-95-5
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which …
Formula:
C5H10N2O3
Purity:
99.92%
Color and Shape:
White Or Off-White Powder
Molecular weight:
146.14
Ref: TM-T6468
| 1ml | 46.00 € | ||
| 25mg | 35.00 € | ||
| 50mg | 50.00 € | ||
| 100mg | 65.00 € | ||
| 200mg | 87.00 € | ||
| 500mg | 144.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
IU1
CAS:314245-33-5
IU1(IC50=4.7 μ M), a reversible, specific human USP14 proteasome inhibitor, can penetrate the cell.
Formula:
C18H21FN2O
Purity:
98% - 99.30%
Color and Shape:
Solid
Molecular weight:
300.37
Ref: TM-T6107
| 5mg | 59.00 € | ||
| 10mg | 82.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 234.00 € | ||
| 100mg | 416.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
PF-3845
CAS:1196109-52-0
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing …
Formula:
C24H23F3N4O2
Purity:
99.54% - 99.58%
Color and Shape:
Solid
Molecular weight:
456.46
Ref: TM-T6043
| 2mg | 41.00 € | ||
| 5mg | 59.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 203.00 € | ||
| 50mg | 380.00 € | ||
| 100mg | 554.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Eprenetapopt
CAS:5291-32-7
Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor …
Formula:
C10H17NO3
Purity:
98.75% - 99.57%
Color and Shape:
Solid
Molecular weight:
199.25
Ref: TM-T4414
| 5mg | 72.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 360.00 € | ||
| 100mg | 638.00 € | ||
| 500mg | 1,299.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
ML-SA1
CAS:332382-54-4
ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by …
Formula:
C22H22N2O3
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
362.42
Ref: TM-T23004
| 5mg | 51.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 148.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | 357.00 € | ||
| 200mg | 537.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
Dynasore
CAS:304448-55-3
Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) …
Formula:
C18H14N2O4
Purity:
95.85% - 99.89%
Color and Shape:
Solid
Molecular weight:
322.31
Ref: TM-T1848
| 5mg | 49.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 138.00 € | ||
| 50mg | 260.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 554.00 € | ||
| 500mg | 866.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
NH125
CAS:278603-08-0
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over …
Formula:
C27H45IN2
Purity:
98.04%
Color and Shape:
Solid
Molecular weight:
524.56
Ref: TM-T6605
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 260.00 € | ||
| 50mg | 446.00 € | ||
| 100mg | 640.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
CX546
CAS:215923-54-9
CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also …
Formula:
C14H17NO3
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
247.29
Ref: TM-T7580
| 5mg | 40.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 166.00 € | ||
| 100mg | 242.00 € | ||
| 200mg | 357.00 € |
Estimated delivery in United States, on Monday 16 Dec 2024
