Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1431 products of "Autophagy"
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Tacrolimus monohydrate
CAS:<p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>Formula:C44H71NO13Purity:97.07% - 98.05%Color and Shape:SolidMolecular weight:822.05Norepinephrine
CAS:<p>Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway.</p>Formula:C8H11NO3Purity:99.43% - 99.84%Color and Shape:Colorless Microcrystals SolidMolecular weight:169.18Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formula:C24H25N5OPurity:98% - 99.06%Color and Shape:SolidMolecular weight:399.49Glucosamine sulfate
CAS:<p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>Formula:C6H13NO5·H2SO4Purity:99.64%Color and Shape:White CrystalMolecular weight:277.25Maprotiline
CAS:<p>Maprotiline blocks norepinephrine uptake, has antidepressant properties, and fights cancer by inducing apoptosis and inhibiting ERK and CRABP1.</p>Formula:C20H23NColor and Shape:SolidMolecular weight:277.4Lucanthone hydrochloride
CAS:<p>Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.</p>Formula:C20H25ClN2OSColor and Shape:SolidMolecular weight:376.94Cucurbitacin E
CAS:<p>Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.</p>Formula:C32H44O8Purity:98.88% - 99.87%Color and Shape:SolidMolecular weight:556.69CZC-54252
CAS:CZC-54252 is a potent inhibitor of LRRK2.Formula:C22H25ClN6O4SPurity:99.39%Color and Shape:SolidMolecular weight:504.99Vistusertib
CAS:Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formula:C25H30N6O3Purity:97.08% - 99.06%Color and Shape:SolidMolecular weight:462.54Trifluoperazine
CAS:<p>Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.</p>Formula:C21H24F3N3SPurity:98.3% - 99.46%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:407.5Nilotinib monohydrochloride monohydrate
CAS:<p>Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosine</p>Formula:C28H22F3N7O·HCl·H2OPurity:99.93%Color and Shape:SolidMolecular weight:583.99Autogramin-2
CAS:<p>Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either</p>Formula:C21H27N3O4SPurity:96.25%Color and Shape:SolidMolecular weight:417.52Vismodegib
CAS:<p>Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).</p>Formula:C19H14Cl2N2O3SPurity:98% - 99.82%Color and Shape:SolidMolecular weight:421.3PFK-158
CAS:<p>PFK-158 is an effective and specific inhibitor PFKFB3.</p>Formula:C18H11F3N2OPurity:95.49% - 99.16%Color and Shape:SolidMolecular weight:328.29Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Formula:C51H82O21Purity:99.51% - 99.63%Color and Shape:SolidMolecular weight:1031.18Trametinib
CAS:<p>Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.</p>Formula:C26H23FIN5O4Purity:98% - 99.96%Color and Shape:SolidMolecular weight:615.39Levosimendan
CAS:<p>Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.</p>Formula:C14H12N6OPurity:99.37% - 99.91%Color and Shape:Yellow Crystalline PowderMolecular weight:280.28DBEQ
CAS:<p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>Formula:C22H20N4Purity:98.93% - ≥95%Color and Shape:SolidMolecular weight:340.42Wogonin
CAS:<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Formula:C16H12O5Purity:98% - 99.8%Color and Shape:Yellow CrystalMolecular weight:284.26SU9516
CAS:<p>SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.</p>Formula:C13H11N3O2Purity:99.34% - 99.87%Color and Shape:SolidMolecular weight:241.25
