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Autophagy

Autophagy

Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.

Found 1430 products of "Autophagy"

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  • GNE-7915 tosylate

    CAS:
    <p>GNE-7915 tosylate is a potent, selective, and brain-penetrant LRRK2 inhibitor, boasting an IC50 value of 9 nM.</p>
    Formula:C26H29F4N5O6S
    Color and Shape:Solid
    Molecular weight:615.6
  • Dehydropachymic acid

    CAS:
    <p>Dehydropachymic acid shows antiinflammatory activity.</p>
    Formula:C33H50O5
    Purity:99.61% - 99.78%
    Color and Shape:Solid
    Molecular weight:526.75
  • Notoginsenoside Fc

    CAS:
    <p>1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.</p>
    Formula:C58H98O26
    Purity:99.22% - 99.94%
    Color and Shape:Solid
    Molecular weight:1211.38
  • Cilofexor

    CAS:
    <p>Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.</p>
    Formula:C28H22Cl3N3O5
    Purity:99.86% - ≥95%
    Color and Shape:Solid
    Molecular weight:586.85
  • Talarozole

    CAS:
    <p>Talarozole is an oral RAMBA for treating acne and psoriasis, inhibiting CYP26A1/26B1 with IC50s of 5.4/0.46 nM.</p>
    Formula:C21H23N5S
    Purity:97.51%
    Color and Shape:Solid
    Molecular weight:377.51
  • Rosuvastatin

    CAS:
    <p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>
    Formula:C22H28FN3O6S
    Purity:95.24% - 99.8%
    Color and Shape:Solid
    Molecular weight:481.54
  • STF-31

    CAS:
    <p>STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.</p>
    Formula:C23H25N3O3S
    Purity:99.55% - >99.99%
    Color and Shape:Solid
    Molecular weight:423.53
  • Lapatinib tosylate

    CAS:
    <p>Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) &amp; 9.8 nM (ErbB-2).</p>
    Formula:C36H34ClFN4O7S2
    Color and Shape:Solid
    Molecular weight:753.26
  • FIPI HCl

    CAS:
    <p>FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.</p>
    Formula:C23H25ClFN5O2
    Color and Shape:Solid
    Molecular weight:457.93
  • Dehydrocorydaline

    CAS:
    <p>1.</p>
    Formula:C22H24NO4
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:366.43
  • Fasudil dihydrochloride

    CAS:
    <p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>
    Formula:C14H19Cl2N3O2S
    Color and Shape:Solid
    Molecular weight:364.29
  • Hydroxychloroquine

    CAS:
    <p>HCQ, an anti-malarial, may induce cancer cell death and is being explored for COVID-19.</p>
    Formula:C18H26ClN3O
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:335.87
  • Fasudil hydrochloride hydrate

    CAS:
    <p>Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.</p>
    Formula:C28H38Cl2N6O5S2
    Color and Shape:Solid
    Molecular weight:673.67
  • Retro-2

    CAS:
    <p>Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.</p>
    Formula:C19H16N2OS
    Purity:98.15%
    Color and Shape:Solid
    Molecular weight:320.41
  • PI-1840

    CAS:
    <p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>
    Formula:C22H26N4O3
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:394.47
  • Liensinine

    CAS:
    <p>1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.</p>
    Formula:C37H42N2O6
    Purity:98.92% - 99.93%
    Color and Shape:White-Like Powder
    Molecular weight:610.74
  • Atorvastatin hemicalcium salt

    CAS:
    <p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>
    Formula:C33H34FN2O5Ca
    Purity:99.27% - >99.99%
    Color and Shape:White Crystalline Powder
    Molecular weight:577.67
  • PHA-665752

    CAS:
    <p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), &gt;50-fold selectivity for c-Met than STKs or RTKs.</p>
    Formula:C32H34Cl2N4O4S
    Purity:97.05% - 98.82%
    Color and Shape:Solid
    Molecular weight:641.61
  • Purvalanol A

    CAS:
    <p>Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.</p>
    Formula:C19H25ClN6O
    Purity:98.13% - 99.68%
    Color and Shape:Powder
    Molecular weight:388.89
  • Tacrolimus monohydrate

    CAS:
    <p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>
    Formula:C44H71NO13
    Purity:97.07% - 98.05%
    Color and Shape:Solid
    Molecular weight:822.05