
Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Found 1430 products of "Autophagy"
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GNE-7915 tosylate
CAS:<p>GNE-7915 tosylate is a potent, selective, and brain-penetrant LRRK2 inhibitor, boasting an IC50 value of 9 nM.</p>Formula:C26H29F4N5O6SColor and Shape:SolidMolecular weight:615.6Dehydropachymic acid
CAS:<p>Dehydropachymic acid shows antiinflammatory activity.</p>Formula:C33H50O5Purity:99.61% - 99.78%Color and Shape:SolidMolecular weight:526.75Notoginsenoside Fc
CAS:<p>1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.</p>Formula:C58H98O26Purity:99.22% - 99.94%Color and Shape:SolidMolecular weight:1211.38Cilofexor
CAS:<p>Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.</p>Formula:C28H22Cl3N3O5Purity:99.86% - ≥95%Color and Shape:SolidMolecular weight:586.85Talarozole
CAS:<p>Talarozole is an oral RAMBA for treating acne and psoriasis, inhibiting CYP26A1/26B1 with IC50s of 5.4/0.46 nM.</p>Formula:C21H23N5SPurity:97.51%Color and Shape:SolidMolecular weight:377.51Rosuvastatin
CAS:<p>Rosuvastatin (ZD4522) is an inhibitor of HMG-CoA reductase (HMGCR). Rosuvastatin has hypolipidemic and antiatherosclerotic effects. Cost-effective and quality-assured.</p>Formula:C22H28FN3O6SPurity:95.24% - 99.8%Color and Shape:SolidMolecular weight:481.54STF-31
CAS:<p>STF-31 is an inhibitor of glucose transporter 1 (GLUT1) with IC50 of 1 μM.</p>Formula:C23H25N3O3SPurity:99.55% - >99.99%Color and Shape:SolidMolecular weight:423.53Lapatinib tosylate
CAS:<p>Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).</p>Formula:C36H34ClFN4O7S2Color and Shape:SolidMolecular weight:753.26FIPI HCl
CAS:<p>FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.</p>Formula:C23H25ClFN5O2Color and Shape:SolidMolecular weight:457.93Dehydrocorydaline
CAS:<p>1.</p>Formula:C22H24NO4Purity:99.84%Color and Shape:SolidMolecular weight:366.43Fasudil dihydrochloride
CAS:<p>Fasudil dihydrochloride (HA-1077/AT877) is a RhoA/ROCK inhibitor with kinase-blocking properties and acts as a vasodilator.</p>Formula:C14H19Cl2N3O2SColor and Shape:SolidMolecular weight:364.29Hydroxychloroquine
CAS:<p>HCQ, an anti-malarial, may induce cancer cell death and is being explored for COVID-19.</p>Formula:C18H26ClN3OPurity:99.79%Color and Shape:SolidMolecular weight:335.87Fasudil hydrochloride hydrate
CAS:<p>Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.</p>Formula:C28H38Cl2N6O5S2Color and Shape:SolidMolecular weight:673.67Retro-2
CAS:<p>Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, it protects HeLa cells against Ricin, Stx1 and Stx2.</p>Formula:C19H16N2OSPurity:98.15%Color and Shape:SolidMolecular weight:320.41PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Liensinine
CAS:<p>1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.</p>Formula:C37H42N2O6Purity:98.92% - 99.93%Color and Shape:White-Like PowderMolecular weight:610.74Atorvastatin hemicalcium salt
CAS:<p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>Formula:C33H34FN2O5CaPurity:99.27% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:577.67PHA-665752
CAS:<p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.</p>Formula:C32H34Cl2N4O4SPurity:97.05% - 98.82%Color and Shape:SolidMolecular weight:641.61Purvalanol A
CAS:<p>Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.</p>Formula:C19H25ClN6OPurity:98.13% - 99.68%Color and Shape:PowderMolecular weight:388.89Tacrolimus monohydrate
CAS:<p>Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FKBP to form a complex.</p>Formula:C44H71NO13Purity:97.07% - 98.05%Color and Shape:SolidMolecular weight:822.05
