Sigma receptor
Sigma receptors are unique binding sites that, unlike traditional GPCRs, do not fit into the classical categories of receptor proteins. They are involved in modulating neurotransmitter systems and have been implicated in various neurological and psychiatric disorders. Sigma receptors are also associated with cell survival, and their ligands are being explored for therapeutic applications in neuroprotection, cancer, and pain management. At CymitQuimica, we offer a selection of high-quality sigma receptor modulators to support your research in neuroscience, oncology, and receptor biology.
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Siramesine
CAS:147817-50-3
Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to …
Formula:
C30H31FN2O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
454.58
Ref: TM-T4620
| 5mg | 193.00 € | ||
| 10mg | 293.00 € | ||
| 25mg | 447.00 € | ||
| 50mg | 688.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
σ1 Receptor antagonist-1
CAS:1204401-49-9
σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.
Formula:
C21H23NOS
Purity:
99.80%
Color and Shape:
Solid
Molecular weight:
337.48
Ref: TM-T9244
| 2mg | 37.00 € | ||
| 5mg | 53.00 € | ||
| 10mg | 85.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 259.00 € | ||
| 100mg | 377.00 € | ||
| 200mg | 542.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cutamesine dihydrochloride
CAS:165377-44-6
Cutamesine dihydrochloride is a σ1 receptor agonist, selective over σ2, combating cardiomyocyte hypertrophy and improving …
Formula:
C23H32N2O2·2HCl
Purity:
98.83% - 99%
Color and Shape:
Solid
Molecular weight:
441.43
Ref: TM-T3597
| 2mg | 43.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 99.00 € | ||
| 25mg | 220.00 € | ||
| 50mg | 418.00 € | ||
| 100mg | 618.00 € | ||
| 500mg | 1,291.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
4-IBP
CAS:155798-08-6
4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 …
Formula:
C19H21IN2O
Purity:
99.11%
Color and Shape:
Solid
Molecular weight:
420.29
Ref: TM-T4596
| 5mg | 36.00 € | ||
| 10mg | 57.00 € | ||
| 25mg | 106.00 € | ||
| 50mg | 180.00 € | ||
| 100mg | 264.00 € | ||
| 200mg | 391.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
EST64454 hydrochloride
CAS:1950569-11-5
EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the …
Formula:
C18H23ClF2N4O2
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
400.85
Ref: TM-T8834
| 1mg | 51.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 155.00 € | ||
| 25mg | 318.00 € | ||
| 50mg | 515.00 € | ||
| 100mg | 817.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Siramesine hydrochloride
CAS:224177-60-0
Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown …
Formula:
C30H32ClFN2O
Purity:
100% - 99.75%
Color and Shape:
Solid
Molecular weight:
491.04
Ref: TM-T1885
| 1mg | 60.00 € | ||
| 2mg | 86.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 349.00 € | ||
| 50mg | 522.00 € | ||
| 100mg | 735.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BD-1047 dihydrobromide
CAS:138356-21-5
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in …
Formula:
C13H22Br2Cl2N2
Purity:
98.13% - 99.39%
Color and Shape:
Solid
Molecular weight:
437.04
Ref: TM-T1740
| 1mg | 36.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 166.00 € | ||
| 50mg | 284.00 € | ||
| 100mg | 481.00 € | ||
| 1mL*10mM (DMSO) | 75.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BD 1008 dihydrobromide
CAS:138356-09-9
BD 1008 dihydrobromide: selective σ1 receptor antagonist (Ki=2 nM), high σ1 and moderate σ2 affinity.
Formula:
C15H24Br2Cl2N2
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
463.08
Ref: TM-T21788
| 1mg | 64.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 200.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 500.00 € | ||
| 100mg | 712.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Dimemorfan phosphate
CAS:36304-84-4
Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a …
Formula:
C18H25N·H3O4P
Purity:
99.67%
Color and Shape:
Solid
Molecular weight:
353.4
Ref: TM-T5027
| 100mg | 43.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Blarcamesine hydrochloride
CAS:195615-84-0
Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).
Formula:
C19H24ClNO
Purity:
98.62% - 99.95%
Color and Shape:
Solid
Molecular weight:
317.85
Ref: TM-T4111
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 448.00 € | ||
| 100mg | 640.00 € | ||
| 500mg | 1,379.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
S1RA hydrochloride
CAS:1265917-14-3
S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, …
Formula:
C20H24ClN3O2
Purity:
98% - 99.78%
Color and Shape:
Solid
Molecular weight:
373.87
Ref: TM-T4229
| 1mg | 38.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 353.00 € | ||
| 100mg | 518.00 € | ||
| 500mg | 1,004.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Blarcamesine
CAS:195615-83-9
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.
Formula:
C19H23NO
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
281.39
Ref: TM-T7780
| 5mg | 47.00 € | ||
| 10mg | 60.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 172.00 € | ||
| 100mg | 276.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BD1063 dhydrochloride
CAS:206996-13-6
BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
Formula:
C13H20Cl4N2
Purity:
99.52% - ≥95%
Color and Shape:
Solid
Molecular weight:
346.12
Ref: TM-T7488
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 335.00 € | ||
| 100mg | 493.00 € | ||
| 200mg | 693.00 € | ||
| 500mg | 1,050.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ditolylguanidine
CAS:97-39-2
Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).
Formula:
C15H17N3
Purity:
98.42%
Color and Shape:
White To Pinkish Solid Powder
Molecular weight:
239.32
Ref: TM-T5969
| 1g | 35.00 € | ||
| 1mL*10mM (DMSO) | 34.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Pre-084
CAS:138847-85-5
Pre-084 is a high affinity, selective σ1 agonist.
Formula:
C19H28ClNO3
Purity:
99.91%
Color and Shape:
Solid
Molecular weight:
353.88
Ref: TM-T3198
| 10mg | 469.00 € | ||
| 50mg | 1,878.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
4-PPBP maleate
CAS:201216-39-9
4-PPBP maleate: potent σ1 agonist, selective NR1a/2B NMDA antagonist, neuroprotective.
Formula:
C25H31NO4
Purity:
99.54%
Color and Shape:
Solid
Molecular weight:
409.52
Ref: TM-T22513
| 5mg | 73.00 € | ||
| 10mg | 109.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,093.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
Sigma-LIGAND-1
CAS:139652-01-0
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM …
Formula:
C27H33NO4
Purity:
100%
Color and Shape:
Solid
Molecular weight:
435.56
Ref: TM-T13510
| 1mg | 94.00 € | ||
| 5mg | 236.00 € | ||
| 10mg | 350.00 € | ||
| 25mg | 548.00 € | ||
| 50mg | 738.00 € | ||
| 100mg | 1,015.00 € | ||
| 500mg | 2,019.00 € | ||
| 1mL*10mM (DMSO) | 276.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
NE-100 hydrochloride
CAS:149409-57-4
NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 …
Formula:
C23H34ClNO2
Purity:
98.85%
Color and Shape:
Solid
Molecular weight:
391.98
Ref: TM-T20797
| 1mg | 45.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 134.00 € | ||
| 25mg | 217.00 € | ||
| 50mg | 323.00 € | ||
| 100mg | 479.00 € | ||
| 200mg | 688.00 € | ||
| 500mg | 1,019.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
SARS-CoV-2-IN-57
CAS:1265624-68-7
SARS-CoV-2-IN-57 (compound (+)-R-26) is a potent inhibitor of SARS-CoV-2 with an IC50 of 80 nM …
Formula:
C23H37N3O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
371.56
Ref: TM-T79356
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
BMY-14802 hydrochloride
CAS:105565-55-7
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 …
Formula:
C18H23ClF2N4O
Purity:
98.64%
Color and Shape:
Solid
Molecular weight:
384.85
Ref: TM-T22612
| 5mg | 49.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 230.00 € | ||
| 100mg | 343.00 € | ||
| 200mg | 487.00 € |
Estimated delivery in United States, on Wednesday 22 Jan 2025
