Dopamine Receptor
Dopamine receptors are a group of GPCRs that respond to the neurotransmitter dopamine, playing a key role in the regulation of movement, motivation, reward, and several cognitive functions. These receptors are divided into D1-like and D2-like families, each with distinct functions and pharmacological profiles. Dopamine receptor modulators are widely studied for their applications in treating Parkinson's disease, schizophrenia, addiction, and other neuropsychiatric disorders. At CymitQuimica, we offer a wide range of high-quality dopamine receptor modulators to support your research in neuroscience, mental health, and GPCR signaling.
Found 407 products of "Dopamine Receptor"
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Quinelorane dihydrochloride
CAS:<p>Dopamine D2 and D3 receptor agonist</p>Formula:C14H23ClN4Purity:98%Color and Shape:SolidMolecular weight:282.81SKF-83822
CAS:<p>SKF-83822 is an agonist of dopamine D1-like receptor.</p>Formula:C20H22ClNO2Purity:98%Color and Shape:SolidMolecular weight:343.85BRD5814
CAS:<p>BRD5814 is a highly brain penetrant β-arrestin biased D2R antagonist.</p>Formula:C21H23ClF3NO2Color and Shape:SolidMolecular weight:413.86SB-277011 dihydrochloride
CAS:<p>SB-277011 dihydrochloride: potent, selective D3 antagonist; orally bioavailable; crosses blood-brain barrier; pKi 8.0 for D3 receptor.</p>Formula:C28H32Cl2N4OPurity:98%Color and Shape:SolidMolecular weight:511.49PF2562
CAS:<p>PF2562: Dopamine D1 ligand, agonist/partial agonist. Binds D1 receptor (Ki: 113 nM), active in cAMP assay (EC50: 568 nM).</p>Formula:C19H17N5OPurity:98%Color and Shape:SolidMolecular weight:331.37Odapipam
CAS:<p>Odapipam is a selective and high affinity antagonist of benzazepine dopamine D1 receptor (Kd of 0.18 nM).</p>Formula:C19H20ClNO2Purity:98%Color and Shape:SolidMolecular weight:329.82Lenperone
CAS:<p>Lenperone is a butyrophenone antipsychotic. Like other major tranquilizers, It has some alpha-adrenergic blocking action and is antiemetic.</p>Formula:C22H23F2NO2Color and Shape:SolidMolecular weight:371.42BAK2-66
CAS:<p>BAK2-66 is a selective antagonist of the dopamine D3 receptor.</p>Formula:C23H24Cl2FN3O2Purity:98%Color and Shape:SolidMolecular weight:464.36Brl 20596
CAS:<p>Brl 20596 is a central dopamine antagonist in the class of anilide.</p>Formula:C20H24ClN3O2Purity:98%Color and Shape:SolidMolecular weight:373.88FAUC-3019
CAS:<p>FAUC-3019 is a partial agonist of the dopamine D(4) receptor.</p>Formula:C22H24N2OColor and Shape:SolidMolecular weight:332.44Lergotrile
CAS:<p>Lergotrile is used as an enzyme Inhibitor (Prolactin).</p>Formula:C17H18ClN3Purity:98%Color and Shape:SolidMolecular weight:299.8CJB-090 2HCl
CAS:<p>CJB-090 2HCl is a partial agonist of the dopamine D3 receptor.</p>Formula:C26H30Cl4N4OColor and Shape:SolidMolecular weight:556.35Gyki 32887
CAS:<p>Gyki 32887 is a dopamine agonist.</p>Formula:C23H28N6O6SPurity:98%Color and Shape:SolidMolecular weight:516.57Amitifadine free base
CAS:<p>Amitifadine (DOV-21947/EB-1010), an antidepressant SNDRI, curbs binge drinking and negative effects in animals with alcoholism-depression.</p>Formula:C11H11Cl2NColor and Shape:SolidMolecular weight:228.12A 69024
CAS:<p>A 69024 is a highly selective antagonist of dopamine D-1 receptor.</p>Formula:C20H24BrNO4Purity:98%Color and Shape:SolidMolecular weight:422.31Seproxetine HCl
CAS:<p>Seproxetine HCl, a more active enantiomer of N-desmethyl metabolite fluoxetine, works by selectively inhibiting the serotonin uptake carrier.</p>Formula:C16H17ClF3NOPurity:98%Color and Shape:SolidMolecular weight:331.76Lergotrile mesylate
CAS:<p>Lergotrile mesylate, an ergoline derivative, suppresses prolactin in vivo and in vitro.</p>Formula:C18H22ClN3O3SColor and Shape:SolidMolecular weight:395.9Bromperidol decanoate
CAS:<p>Bromperidol decanoate is an antipsychotic agent that is utilized for long-term maintenance treatment for schizophrenia.</p>Formula:C31H41BrFNO3Color and Shape:SolidMolecular weight:574.56LY 171859
CAS:<p>LY 171859 is an agonist of D2-receptor.</p>Formula:C17H14O5Purity:98%Color and Shape:SolidMolecular weight:298.29Nor-SCH-12679 Maleate
CAS:<p>Nor-SCH-12679 Maleate is a D1-dopamine receptor antagonist.</p>Formula:C22H25NO6Purity:98%Color and Shape:SolidMolecular weight:399.44Clothixamide
CAS:<p>Clothixamide（Clotixamide） is a thioxanthene derivative with antipsychotic activity.</p>Formula:C24H28ClN3OSPurity:95.51%Color and Shape:SolidMolecular weight:442.02CI-943
CAS:<p>CI-943 is a novel potential antipsychotic drug that does not bind to dopamine (DA) receptors and has some developmental neurotoxicity.</p>Formula:C12H17N5Purity:98%Color and Shape:SolidMolecular weight:231.33'-Fluorobenzylspiperone maleate
CAS:<p>ligand for the D2 receptor</p>Formula:C34H35F2N3O6Purity:98%Color and Shape:SolidMolecular weight:619.66Butaclamol free base
CAS:<p>Butaclamol is a typical antipsychotic which was never marketed. It also acts as a dopamine receptor antagonist.</p>Formula:C25H31NOPurity:98%Color and Shape:SolidMolecular weight:361.52PD 118440
CAS:<p>PD 118440 is a Dopamine antagonist. PD 118440 is an orally active dopamine (DA) agonists with pronounced central nervous system effects.</p>Formula:C11H17N3SPurity:98%Color and Shape:SolidMolecular weight:223.34Sch 24518
CAS:<p>Sc h24518 is an antagonist of D1 receptor.</p>Formula:C16H17BrClNOPurity:98%Color and Shape:SolidMolecular weight:354.67Dicarbine
CAS:<p>Double carbene blocks dopamine receptors, aiding schizophrenia and alcoholism research; it maintains defense reflexes despite mid-brain stimulation.</p>Formula:C13H18N2Purity:98%Color and Shape:SolidMolecular weight:202.3L-750,667 Trihydrochloride
CAS:<p>L-750,667 Trihydrochloride is a selective D4 receptor antagonist, reverses the dopamine-induced inhibition of cAMP accumulation in the central nervous system.</p>Formula:C18H22Cl3IN4Purity:99.63%Color and Shape:SolidMolecular weight:527.666-Chloromelatonin
CAS:<p>6-Chloromelatonin: potent, stable melatonin agonist; binds MT2 receptors (pKi=9.77); could help research sleep disorders.</p>Formula:C13H15ClN2O2Purity:98.01% - 99.25%Color and Shape:SolidMolecular weight:266.72A-77636
CAS:<p>A-77636 is a potent, selective, and long-acting oral dopamine D1 receptor agonist with an effective concentration (EC50) of 1.1 nM and a corresponding pEC50</p>Formula:C20H27NO3Purity:98%Color and Shape:SolidMolecular weight:329.43D4R agonist-1
CAS:<p>D4R agonist-1 is a selective and potent D4R partial agonist (Ki:2.2 nM).D4R agonist-1 can be used to study neurological diseases.</p>Formula:C19H22N4SPurity:98.44%Color and Shape:SolidMolecular weight:338.47PG 01037 dihydrochloride
CAS:<p>PG 01037 dihydrochloride (PG-01037 2HCl) is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM.</p>Formula:C26H28Cl4N4OPurity:99.89%Color and Shape:SolidMolecular weight:554.34SKF83959
CAS:<p>SKF83959: dopamine D1 partial agonist, Ki: D1(1.18 nM), D5(7.56 nM), D2(920 nM), D3(399 nM); improves cognitive function in depression, Alzheimer's.</p>Formula:C18H20ClNO2Purity:98.68%Color and Shape:SolidMolecular weight:317.81WAY-260022
CAS:<p>WAY-260022 is the norepinephrine transporter inhibitor.</p>Formula:C21H31F3N2O2Purity:97.61% - 99.41%Color and Shape:SolidMolecular weight:400.48UNC9975
CAS:<p>UNC9975 is a D(2) receptor agonist with antipsychotic activity used in the study of neurologic disorders such as schizophrenia.</p>Formula:C23H28Cl2N4O2Purity:98.78% - 98.78%Color and Shape:SolidMolecular weight:463.4Medifoxamine
CAS:<p>Medifoxamine (LG 152) is a selective non-monoamine oxidase inhibitor that exhibits antidepressant activity through inhibition of 5 HT reuptake.Medifoxamine</p>Formula:C16H19NO2Purity:97.14%Color and Shape:SolidMolecular weight:257.33Halopemide
CAS:<p>Halopemide is a potent inhibitor of PLD (IC50 = 220 and 310 nM for human PLD1 and PLD2).</p>Formula:C21H22ClFN4O2Purity:96.57%Color and Shape:SolidMolecular weight:416.88Benperidol
CAS:<p>Benperidol (Anquil), a butanone derivative, has antipsychotic effects and blocks D2 receptors; useful in PET scans.</p>Formula:C22H24FN3O2Purity:99.91%Color and Shape:SolidMolecular weight:381.44SB-277011
CAS:<p>SB-277011A: dopamine D3 antagonist, pKi 8.0 (D3), 6.0 (D2), 5.0 (5-HT1D), <5.2 (5-HT1B).</p>Formula:C28H30N4OPurity:99.39%Color and Shape:SolidMolecular weight:438.56Milenperone
CAS:<p>Milenperone (R 34009) is a novel anti-invasive compound for the control of behavioral disorders in patients with epilepsy and alcoholism.</p>Formula:C22H23ClFN3O2Purity:98.09% - 99.84%Color and Shape:SolidMolecular weight:415.89PF-00217830
CAS:<p>PF-00217830: agonist at serotonin 1A & dopamine D2, antagonist at serotonin 2A, potential schizophrenia study drug.</p>Formula:C26H30N4O2Purity:98.72%Color and Shape:SolidMolecular weight:430.54U 99194 maleate
CAS:<p>U 99194 maleate (U-99194A maleate) is a D3 antagonist and increases social behaviors of isolation-induced aggressive male mice.</p>Formula:C21H31NO6Purity:99.45%Color and Shape:SolidMolecular weight:393.47PD 168568 dihydrochloride
CAS:<p>PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).</p>Formula:C22H29Cl2N3OPurity:99.71%Color and Shape:SolidMolecular weight:422.39NGD 94-1
CAS:<p>NGD 94-1 is a D4 receptor antagonist that can be used to study psychiatric disorders such as cognitive impairment.</p>Formula:C18H20N6Purity:99.61%Color and Shape:SolidMolecular weight:320.39MLS1547
CAS:<p>MLS1547 is a potent D2 receptor G protein-biased agonist (Ki=1.2 μM, EC50=0.37 μM in Ca2+ assay).</p>Formula:C19H19ClN4OPurity:99.64%Color and Shape:SolidMolecular weight:354.837-Hydroxy-DPAT hydrobromide
CAS:<p>7-Hydroxy-DPAT hydrobromide is a D3 dopamine receptor agonist that blocks dopamine reuptake, used in research on neurological diseases.</p>Formula:C16H26BrNOPurity:99.73%Color and Shape:SolidMolecular weight:328.29GBR 12783 dihydrochloride
CAS:<p>GBR 12783 dihydrochloride inhibits dopamine uptake in rats/mice; IC50s: 1.8/1.2 nM. Enhances memory, boosts hippocampal acetylcholine.</p>Formula:C28H34Cl2N2OPurity:98.08%Color and Shape:SolidMolecular weight:485.49Seridopidine
CAS:<p>Seridopidine (ACR343) is a modulator of dopaminergic activity that is used as an oral therapy for schizophrenia, Parkinson's disease, and Tourette's syndrome.</p>Formula:C14H20FNO2SPurity:99.65%Color and Shape:SolidMolecular weight:285.38Ordopidine
CAS:<p>Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity.</p>Formula:C14H20FNO2SPurity:99.39%Color and Shape:SolidMolecular weight:285.38Molindone
CAS:<p>Molindone: antipsychotic for schizophrenia; blocks dopamine, often paired with serotonin; dosage affects error/response rates.</p>Formula:C16H24N2O2Purity:99.37% - 99.46%Color and Shape:Off-White SolidMolecular weight:276.37A-437203
CAS:<p>A-437203 (Lu201640), selective D3 antagonist with Ki: D2-71nM, D3-1.6nM, D4-6220nM; based on 1H-pyrimidin-2-one scaffold.</p>Formula:C20H27F3N6OSPurity:98.80%Color and Shape:SolidMolecular weight:456.53BP14979
CAS:<p>BP14979 is D3R-selective partial agonist.</p>Formula:C23H34N4O2Purity:98.29% - 99.73%Color and Shape:SolidMolecular weight:398.54SK609 HCl
CAS:<p>SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties.</p>Formula:C10H15Cl2NPurity:99.02%Color and Shape:SolidMolecular weight:220.14Remoxipride hydrochloride
CAS:<p>Remoxipride hydrochloride (Roxiam) is a selective antagonist of D2 receptor with IC50s of 1.57 μM, ＞100 μM and 42 μM for D2 receptor, D1 receptor and α1-</p>Formula:C16H24BrClN2O3Purity:99.88%Color and Shape:SolidMolecular weight:407.73CyPPA
CAS:<p>CyPPA enhances SK channels, reducing firing rate and extending apamin-sensitive afterhyperpolarization.</p>Formula:C16H23N5Purity:99.88%Color and Shape:SolidMolecular weight:285.39Fananserin
CAS:<p>Fananserin: Oral 5-HT2A antagonist (Ki=0.37 nM, rat), blocks human D4 receptor (Ki=2.93 nM).</p>Formula:C23H24FN3O2SPurity:99.88%Color and Shape:SolidMolecular weight:425.52CCG 203769
CAS:<p>CCG 203769 (Thiadiazolidinone (TDZD) deriv. 6) is a selective inhibitor of RGS4 with an IC50 of 17 nM for the RGS4-Gαo protein-protein interaction.</p>Formula:C8H14N2O2SPurity:99.88%Color and Shape:SolidMolecular weight:202.27Sonepiprazole
CAS:<p>Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation</p>Formula:C21H27N3O3SPurity:99.81%Color and Shape:SolidMolecular weight:401.52CY 208-243
CAS:<p>CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.</p>Formula:C19H18N2Purity:98%Color and Shape:SolidMolecular weight:274.36Timiperone
CAS:<p>Timiperone exhibits a high affinity for cerebral dopamine D2 receptors, demonstrating antipsychotic activity as it mitigates stereotyped behavior.</p>Formula:C22H24FN3OSPurity:98%Color and Shape:SolidMolecular weight:397.51ABT-670
CAS:<p>ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.</p>Formula:C19H23N3O2Purity:98%Color and Shape:SolidMolecular weight:325.4SKF 81297
CAS:<p>SKF 81297 is a selective and potent agonist for the dopamine D1 receptor [1].</p>Formula:C16H16ClNO2Purity:98%Color and Shape:SolidMolecular weight:289.76FAUC-312
CAS:<p>FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.</p>Formula:C21H26N4Purity:98%Color and Shape:SolidMolecular weight:334.46LY3154885
CAS:<p>LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).</p>Formula:C23H23Cl2N3O2Color and Shape:SolidMolecular weight:444.35Quinpirole dihydrochloride
CAS:<p>Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.</p>Formula:C13H23Cl2N3Purity:98%Color and Shape:SolidMolecular weight:292.25Pentiapine
CAS:<p>Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.</p>Formula:C15H17N5SPurity:99.35%Color and Shape:SolidMolecular weight:299.39AJ-76 hydrochloride
CAS:<p>AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.</p>Formula:C15H24ClNOColor and Shape:SolidMolecular weight:269.81Carbidine dihydrochloride
CAS:<p>Carbidine, a gamma-carboline derivative, is an atypical antipsychotic that modulates dopamine release and tyrosine hydroxylase activity.</p>Formula:C13H20Cl2N2Purity:98.59%Color and Shape:SolidMolecular weight:275.217UWA-101 hydrochloride
CAS:<p>UWA-101 hydrochloride is a selective, non-cytotoxic inhibitor of DAT/SERT, demonstrating EC50 values of 3.6 µM for DAT and 2.3 µM for SERT inhibition. It mitigates motor disorders and other side effects associated with dopaminergic agent use (e.g., L-DOPA) without exhibiting psychotropic effects. This compound is utilized in research focused on neurodegenerative conditions like Parkinson's disease [1] [2].</p>Formula:C13H18ClNO2Color and Shape:SolidMolecular weight:255.74SB-414796
CAS:<p>SB-414796 is a selective antagonist of the dopamine D3 receptor.</p>Formula:C29H36N4O4SPurity:98%Color and Shape:SolidMolecular weight:536.69Naxagolide free base
CAS:<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Formula:C15H21NO2Purity:98%Color and Shape:SolidMolecular weight:247.33Dihydrexidine
CAS:<p>Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.</p>Formula:C17H17NO2Purity:98%Color and Shape:SolidMolecular weight:267.32Z1078601926
CAS:<p>Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].</p>Formula:C14H19FN2OColor and Shape:SolidMolecular weight:250.31Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Formula:C24H27ClN2O2Purity:99.37% - 99.62%Color and Shape:SolidMolecular weight:410.94PW0464
CAS:<p>PW0464 ((Rac)-Razpipadon) is a non-catechol D1R agonist and potent omplete G protein biased ligand with an EC50 (Gs-cAMP)=5.8 nM for neurological disorders.</p>Formula:C19H17F2N3O4Purity:98.78%Color and Shape:SolidMolecular weight:389.35LBT 999
CAS:<p>LBT 999 is used as a dopamine reuptake inhibitor.</p>Formula:C20H26FNO2Color and Shape:SolidMolecular weight:331.42JNJ-37822681 dihydrochloride
CAS:<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Formula:C17H19Cl2F5N4Purity:99.78%Color and Shape:SolidMolecular weight:445.26(+)-Dihydrexidine hydrochloride
CAS:<p>(+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM).</p>Formula:C17H18ClNO2Purity:98%Color and Shape:SolidMolecular weight:303.78Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formula:C22H25Cl2N3O3Purity:99.36%Color and Shape:SolidMolecular weight:450.36LY-368975
CAS:<p>LY-368975 is a potent and selective inhibitor of the norepinephrine (NE) reuptake site. LY-368975 reduces food consumption in rodents.</p>Formula:C17H21NOSColor and Shape:SolidMolecular weight:287.42SKF 81297 hydrobromide
CAS:<p>SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.</p>Formula:C16H17BrClNO2Purity:99.52%Color and Shape:SolidMolecular weight:370.67CP-293019
CAS:<p>CP-293019 is a potent, selective antagonist of dopamine D4 receptor.</p>Formula:C19H22F2N4OPurity:98%Color and Shape:SolidMolecular weight:360.44-Amino-PPHT Hydrobromide
CAS:<p>4-Amino-PPHT Hydrobromide is a precursor for fluorescent labeled Dopamine D2 receptors agonist.</p>Formula:C21H28N2OPurity:98%Color and Shape:SolidMolecular weight:324.46PAOPA
CAS:<p>dopamine D2 receptor modulator</p>Formula:C11H18N4O3Purity:>99.99%Color and Shape:SolidMolecular weight:254.29NMI 8739
CAS:<p>NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor.</p>Formula:C30H41NO3Purity:98.51%Color and Shape:SolidMolecular weight:463.65Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Formula:C24H28FN3OPurity:99.68% - 99.91%Color and Shape:SolidMolecular weight:393.5Dopamine D3 receptor antagonist-1
<p>Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic</p>Formula:C31H35Cl2N3O3Color and Shape:SolidMolecular weight:568.53D4R antagonist-1
<p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>Formula:C21H25F2NO2Color and Shape:SolidMolecular weight:361.43CM699
CAS:<p>CM699 is an effective dual inhibitor of the dopamine transporter (DAT) and Sigma receptor (σR), with IC50 values of 311 nM and 14.1 nM, respectively.</p>Formula:C24H29N3O2Color and Shape:SolidMolecular weight:391.51Dopamine D3 receptor ligand-1
<p>Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:</p>Formula:C27H29N5OColor and Shape:SolidMolecular weight:439.55D1R antagonist 1
CAS:<p>Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].</p>Formula:C22H26BrNO4Purity:98%Color and Shape:SolidMolecular weight:448.35Dopamine D3 receptor antagonist-2
<p>Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.</p>Formula:C23H27Cl2N3O3Color and Shape:SolidMolecular weight:464.38UNC10099984A
CAS:<p>UNC10099984A (Compound 6) is a functionally selective ligand for the dopamine D2 receptor, exhibiting a Ki value of 4.6 nM and an EC50 of 6.2 nM for β-arrestin. This compound is useful for research into central nervous system diseases related to the D2 receptor.</p>Formula:C24H29Cl2N3O2Color and Shape:SolidMolecular weight:462.41Neflumozide
CAS:<p>Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.</p>Formula:C22H23FN4O2Color and Shape:SolidMolecular weight:394.44NMDAR antagonist 5
CAS:<p>NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.</p>Formula:C17H21N3Color and Shape:SolidMolecular weight:267.369D4R antagonis-2
<p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>Formula:C21H23ClF2N2O2Color and Shape:SolidMolecular weight:408.87Lisuride
CAS:<p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>Formula:C20H26N4OColor and Shape:SolidMolecular weight:338.45Cendifensine
CAS:<p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>Formula:C14H17Cl2NOColor and Shape:SolidMolecular weight:286.197Disulergine
CAS:<p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>Formula:C17H24N4O2SPurity:98%Color and Shape:SolidMolecular weight:348.46Dinoxyline
CAS:<p>Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.</p>Formula:C15H13NO3Color and Shape:SolidMolecular weight:255.27
