OX Receptor
Orexin receptors (OX1 and OX2) are GPCRs that bind to orexins, neuropeptides involved in regulating wakefulness, appetite, and energy homeostasis. Dysregulation of orexin signaling is linked to sleep disorders such as narcolepsy, as well as metabolic conditions like obesity. Orexin receptor modulators are being investigated for their therapeutic potential in treating sleep disorders, anxiety, and addiction. At CymitQuimica, we offer a range of high-quality orexin receptor modulators to support your research in sleep biology, metabolism, and neuropharmacology.
Found 40 products of "OX Receptor"
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Filorexant
CAS:Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).Formula:C24H25FN4O2Purity:98.88%Color and Shape:SolidMolecular weight:420.48YNT-185
CAS:YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,Formula:C33H37N5O5SPurity:99.67%Color and Shape:SolidMolecular weight:615.74EMPA
CAS:EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nMFormula:C23H26N4O4SPurity:99.11%Color and Shape:SolidMolecular weight:454.54Ref: TM-T11186
1mg49.00€2mg69.00€5mg92.00€10mg142.00€25mg250.00€50mg375.00€100mg563.00€200mg795.00€1mL*10mM (DMSO)104.00€Seltorexant
CAS:Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain.Formula:C21H22FN7OPurity:99.79% - >99.99%Color and Shape:SolidMolecular weight:407.44Ref: TM-T12877L
1mg34.00€2mg49.00€5mg74.00€10mg98.00€25mg144.00€50mg260.00€100mg358.00€500mg822.00€1mL*10mM (DMSO)82.00€Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Formula:C152H243N47O44S4Purity:98%Color and Shape:SolidMolecular weight:3561.1SB-408124
CAS:SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.Formula:C19H18F2N4OPurity:99.81%Color and Shape:SolidMolecular weight:356.37Suntinorexton
CAS:Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.Formula:C23H28F2N2O4SPurity:99.89%Color and Shape:SolidMolecular weight:466.54Ref: TM-T39807
1mg171.00€5mg418.00€10mg666.00€25mg1,017.00€50mg1,372.00€100mg1,793.00€200mg2,405.00€1mL*10mM (DMSO)428.00€OXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Formula:C79H125N23O22Purity:98%Color and Shape:SolidMolecular weight:1749Orexin B, human
CAS:Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.Formula:C123H212N44O35SPurity:98%Color and Shape:SolidMolecular weight:2899.34Orexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Formula:C154H247N47O46S4Color and Shape:SolidMolecular weight:3621.15Orexin B, rat, mouse
CAS:Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.Formula:C126H215N45O34SPurity:98%Color and Shape:SolidMolecular weight:2936.45[Ala11,D-Leu15]-Orexin B(human)
CAS:OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).Formula:C120H206N44O35SPurity:98%Color and Shape:SolidMolecular weight:2857.28[Ala11,D-Leu15]-Orexin B acetate
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).Formula:C122H210N44O37SPurity:98.18%Color and Shape:SolidMolecular weight:2917.31OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).Formula:C81H126F3N23O24Color and Shape:SolidMolecular weight:1863Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Formula:C154H244N47F3O46S4Purity:98%Color and Shape:SolidMolecular weight:3675.12Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Formula:C130H219N45O40S2Color and Shape:SolidMolecular weight:3116.54Orexin B, rat, mouse TFA
Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.Formula:C128H216F3N45O36SColor and Shape:SolidMolecular weight:3050.42SB-674042
CAS:SB-674042 is a nonpeptide dual antagonist of the appetite peptides OX1 and OX2 receptors.SB-674042 is used in the treatment of depression.Formula:C24H21FN4O2SPurity:99.87% - 99.9%Color and Shape:SolidMolecular weight:448.51TCS 1102
CAS:TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).Formula:C27H26N4O2SPurity:99.35% - 99.52%Color and Shape:SolidMolecular weight:470.59SB-334867 free base
CAS:SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.Formula:C17H13N5O2Purity:99.67% - >99.99%Color and Shape:SolidMolecular weight:319.32Ref: TM-T6140
2mg42.00€5mg70.00€10mg99.00€25mg160.00€50mg226.00€100mg338.00€200mg502.00€1mL*10mM (DMSO)78.00€
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