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DNA/RNA Synthesis

DNA/RNA Synthesis

Inhibitors of DNA and RNA synthesis are compounds that interfere with the replication and transcription processes in cells, thereby preventing the production of essential genetic material. These inhibitors can target various enzymes and proteins involved in nucleic acid synthesis, making them valuable tools for studying the mechanisms of replication, transcription, and translation. They are also used in developing treatments for infections and cancer. At CymitQuimica, we offer a broad spectrum of DNA/RNA synthesis inhibitors to support your research in molecular biology, virology, and therapeutic development.

Found 706 products of "DNA/RNA Synthesis"

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  • TAC

    CAS:
    <p>TAC is a TERT (telomerase reverse transcriptase) activator, promotes telomere synthesis, reduces cellular senescence and inflammatory cytokines</p>
    Formula:C14H12ClF2NO2S
    Purity:99.20%
    Color and Shape:Solid
    Molecular weight:331.77
  • Bromochloroacetonitrile

    CAS:
    <p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>
    Formula:C2HBrClN
    Color and Shape:Solid
    Molecular weight:154.39
  • Vanoxonin

    CAS:
    <p>Vanoxonin is a new thymidylate synthetase inhibitor.</p>
    Formula:C18H25N3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:427.41
  • MRK-952


    <p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>
    Formula:C20H20ClF3N6
    Color and Shape:Solid
    Molecular weight:436.861
  • 5'-O-DMT-2'-O-TBDMS-Ac-rC

    CAS:
    <p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C38H47N3O8Si
    Color and Shape:Solid
    Molecular weight:701.892
  • Uridine triphosphate 13C9,15N2 sodium

    CAS:
    <p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>
    Formula:C9H1415N2NaO15P3
    Color and Shape:Solid
    Molecular weight:517.04
  • Ac-rC Phosphoramidite

    CAS:
    <p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>
    Formula:C47H64N5O9PSi
    Purity:98.29%
    Color and Shape:Solid
    Molecular weight:902.1
  • Remdesivir nucleoside monophosphate

    CAS:
    <p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>
    Formula:C12H14N5O7P
    Color and Shape:Solid
    Molecular weight:371.24
  • 5-BrdUTP sodium salt

    CAS:
    <p>5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.</p>
    Formula:C9H10BrN2Na4O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:634.97
  • RNA splicing modulator 3

    CAS:
    <p>RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].</p>
    Formula:C19H20N6OS
    Color and Shape:Solid
    Molecular weight:380.47
  • 8-NH2-ATP

    CAS:
    <p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>
    Formula:C10H17N6O13P3
    Color and Shape:Solid
    Molecular weight:522.20
  • 3'-Deoxyuridine-5'-triphosphate trisodium


    <p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>
    Formula:C9H12N2Na3O14P3
    Color and Shape:Soild
    Molecular weight:534.08
  • HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt

    CAS:
    <p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>
    Formula:C57H62N8O10S
    Color and Shape:Solid
    Molecular weight:1051.21
  • 2'-OMe-Ac-C Phosphoramidite

    CAS:
    <p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>
    Formula:C42H52N5O9P
    Color and Shape:Solid
    Molecular weight:801.86
  • CW-2


    <p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>
    Formula:C43H42Cl2FN11O10Pt
    Color and Shape:Solid
    Molecular weight:1156.21251
  • Demycarosyl-3D-β-D-digitoxosylmithramycin SK

    CAS:
    <p>Demycarosyl-3D-β-D-digitoxosylmithramycin SK, an analog of Mithramycin, exhibits potent anti-tumor activity.</p>
    Formula:C50H72O23
    Color and Shape:Solid
    Molecular weight:1041.09
  • Bz-rC Phosphoramidite

    CAS:
    <p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>
    Formula:C52H66N5O9PSi
    Color and Shape:Solid
    Molecular weight:964.185
  • DNA Gyrase-IN-15


    <p>DNA Gyrase-IN-15 (Compound 11) is an antibacterial agent that inhibits both DHPS and DNA gyrase, with IC50 values of 1.73 and 0.07 µM, respectively. It shows antimicrobial activity against Enterococcus faecium (MIC of 15.62 µg/mL), Acinetobacter baumannii, Enterobacter (MIC of 7.81 µg/mL), Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Additionally, DNA Gyrase-IN-15 exhibits antibiofilm activity against Enterococcus faecium.</p>
    Formula:C31H26N4O4S2
    Color and Shape:Solid
    Molecular weight:582.693
  • Carbazole

    CAS:
    <p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>
    Formula:C12H9N
    Purity:99.82%
    Color and Shape:Solid
    Molecular weight:167.211
  • Guanosine 5'-triphosphate trisodium salt hydrate

    CAS:
    <p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>
    Formula:C10H18N5NaO15P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:564.185
  • Ribonuclease T1

    CAS:
    <p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>
    Color and Shape:Solid
  • EFdA-TP tetraammonium


    <p>EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.</p>
    Formula:C12H27N9O12P3
    Color and Shape:Solid
    Molecular weight:601.31
  • TS-002902


    <p>TS-002902 is a small molecule inhibitor of TUT4/7, exhibiting antiproliferative activity. It holds potential for use in cancer research.</p>
    Color and Shape:Odour Solid
  • cis-Lomibuvir

    CAS:
    <p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>
    Formula:C25H35NO4S
    Color and Shape:Solid
    Molecular weight:445.61
  • RNA polymerase II-IN-2


    <p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>
    Formula:C41H58N10O12S
    Color and Shape:Solid
    Molecular weight:915.02
  • 7-TFA-ap-7-Deaza-ddA

    CAS:
    <p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>
    Formula:C16H16F3N5O3
    Color and Shape:Solid
    Molecular weight:383.331
  • AV-153

    CAS:
    <p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>
    Formula:C14H19NNaO6
    Color and Shape:Solid
    Molecular weight:320.297
  • 5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Formula:C37H34FN3O7
    Color and Shape:Solid
    Molecular weight:651.68
  • 3'Ome-m7GpppAmpG

    CAS:
    <p>3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.</p>
    Formula:C33H45N15O24P4
    Color and Shape:Solid
    Molecular weight:1159.69
  • 7-Deazaxanthine

    CAS:
    <p>7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.</p>
    Formula:C6H5N3O2
    Color and Shape:Solid
    Molecular weight:151.12
  • FR901463

    CAS:
    <p>FR 901463 is a biochemical.</p>
    Formula:C27H42ClNO8
    Color and Shape:Solid
    Molecular weight:544.08
  • L82-G17

    CAS:
    <p>L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI.</p>
    Formula:C11H9ClN4O2
    Purity:99.69%
    Color and Shape:Solid
    Molecular weight:264.67
  • DMT-5Me-dC(Bz)-CE Phosphoramidite

    CAS:
    <p>DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.</p>
    Formula:C47H54N5O8P
    Color and Shape:Solid
    Molecular weight:847.93
  • 2'-Deoxy-2'-fluoro-l-uridine

    CAS:
    <p>2'-Deoxy-2'-fluoro-1-uridine: an L-nucleoside, inhibits RNA viruses by blocking viral RNA polymerase.</p>
    Formula:C9H11FN2O5
    Color and Shape:Solid
    Molecular weight:246.19
  • Maleuric acid

    CAS:
    <p>Maleuric acid is an anti-mitotic agent for research and boosts growth and fertility in flora and fauna.</p>
    Formula:C5H6N2O4
    Purity:98.92%
    Color and Shape:Solid
    Molecular weight:158.11
  • c-Fos-IN-1


    <p>c-Fos-IN-1 (Compound P16) acts as a c-Jun inhibitor, effectively reducing the mRNA and protein levels of c-Fos. It also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. This compound demonstrates anticancer properties through the inhibition of the ERK/c-Fos/Jun pathway. c-Fos-IN-1 curbs the proliferation and migration of gastric cancer cells, with an IC50 of 2.31 μM for MGC-803 cells, causing cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells. Additionally, c-Fos-IN-1 hampers the growth of gastric cancer tumors.</p>
    Formula:C28H35NO3
    Color and Shape:Solid
    Molecular weight:433.582
  • Deoxythymidine-5'-triphosphate

    CAS:
    <p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>
    Formula:C10H17N2O14P3
    Color and Shape:Solid
    Molecular weight:482.167
  • 5'-O-DMT-N4-Ac-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C32H32FN3O7
    Color and Shape:Solid
    Molecular weight:589.61
  • Suricapavir

    CAS:
    <p>Suricapavir is an effective viral replication inhibitor with antiviral activity.</p>
    Formula:C41H29ClF9N9O4S
    Color and Shape:Solid
    Molecular weight:950.23
  • SR15006

    CAS:
    <p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>
    Formula:C16H20ClN3O4S
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:385.87
  • N6-Methyladenine

    CAS:
    <p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>
    Formula:C6H7N5
    Purity:99.78%
    Color and Shape:Solid
    Molecular weight:149.15
  • Diguanosine 5′-triphosphate

    CAS:
    <p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>
    Formula:C20H27N10O18P3
    Color and Shape:Solid
    Molecular weight:788.409
  • 5'-O-DMT-rU

    CAS:
    <p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>
    Formula:C30H30N2O8
    Color and Shape:Solid
    Molecular weight:546.57
  • 5'-O-TBDMS-dG

    CAS:
    <p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>
    Formula:C16H27N5O4Si
    Color and Shape:Solid
    Molecular weight:381.50
  • (+)-Glaucarubinone


    <p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>
    Formula:C25H34O10
    Color and Shape:Solid
    Molecular weight:494.537
  • Clofarabine-5'-diphosphate trisodium


    <p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H10ClFN5Na3O9P2
    Color and Shape:Solid
    Molecular weight:529.58
  • Mulnitorsen

    CAS:
    <p>Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].</p>
    Formula:C172H217N74O82P17S17
    Color and Shape:Solid
    Molecular weight:5704.66
  • Cy5-dATP


    <p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>
    Formula:C47H58N7O19P3S2
    Color and Shape:Solid
    Molecular weight:1182.05
  • 5'-O-TBDMS-N2-ibu-dG

    CAS:
    <p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>
    Formula:C20H33N5O5Si
    Color and Shape:Solid
    Molecular weight:451.59
  • Pyrindamycin A

    CAS:
    <p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>
    Formula:C26H26ClN3O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:543.95
  • YL-5092


    <p>YL-5092 is an inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). It inhibits acute myeloid leukemia cells with an IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor activity in xenograft mice models using MOLM-13 or U937 cells.</p>
    Formula:C22H14F3N3O2S
    Color and Shape:Solid
    Molecular weight:441.43
  • 5'-O-DMT-N2-DMF-dG

    CAS:
    <p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>
    Formula:C34H36N6O6
    Color and Shape:Solid
    Molecular weight:624.698
  • ddGTP trisodium


    <p>ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.</p>
    Formula:C10H13N5Na3O12P3
    Color and Shape:Solid
    Molecular weight:557.13
  • N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium

    CAS:
    <p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>
    Formula:C21H35N12O17P3
    Color and Shape:Solid
    Molecular weight:820.49
  • (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor,reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purity:99.42%
    Color and Shape:Soild
    Molecular weight:502.65
  • wrwycr-NH2 TFA


    <p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>
    Color and Shape:Odour Solid
  • IBU-DC Phosphoramidite

    CAS:
    <p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>
    Formula:C43H54N5O8P
    Color and Shape:Solid
    Molecular weight:799.906
  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    <p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>
    Formula:C10H14N5Na2O8P
    Color and Shape:Solid
    Molecular weight:409.202
  • TS-002266

    CAS:
    <p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>
    Formula:C31H32Cl2N6O5
    Purity:98.18%
    Color and Shape:Soild
    Molecular weight:639.53
  • Vasoactive intestinal contractor

    CAS:
    <p>Vasoactive intestinal contractor, a novel member of the endothelin family, stimulates a rapid increase in intracellular Ca2+ concentration in fura-2-overexpressed Swiss 3T3 cells [1.</p>
    Formula:C116H161N27O32S4
    Color and Shape:Solid
    Molecular weight:2573.94
  • R-1479

    CAS:
    <p>R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.</p>
    Formula:C9H12N6O5
    Purity:98.11% - 99.95%
    Color and Shape:Solid
    Molecular weight:284.23
  • 12R-LOX-IN-2

    CAS:
    <p>12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.</p>
    Formula:C19H13NO
    Purity:99.84%
    Color and Shape:Solid
    Molecular weight:271.31
  • Clofarabine-5'-diphosphate

    CAS:
    <p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>
    Formula:C10H13ClFN5O9P2
    Color and Shape:Solid
    Molecular weight:463.64
  • 5'-O-TBDMS-Bz-dA

    CAS:
    <p>5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.</p>
    Formula:C23H31N5O4Si
    Color and Shape:Solid
    Molecular weight:469.617
  • m7GpppAmpG

    CAS:
    <p>M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].</p>
    Formula:C32H43N15O24P4
    Color and Shape:Solid
    Molecular weight:1145.66
  • Antipain

    CAS:
    <p>Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.</p>
    Formula:C27H44N10O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:604.713
  • DG1


    <p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>
    Formula:C19H17N5O5S
    Color and Shape:Solid
    Molecular weight:427.43
  • 13-TP


    <p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>
    Formula:C12H19F2N6O12P3
    Color and Shape:Solid
    Molecular weight:570.23
  • Brr2-IN-2


    <p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>
    Formula:C21H25FN4O2
    Color and Shape:Solid
    Molecular weight:384.45
  • Thailanstatin C

    CAS:
    <p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>
    Formula:C30H46ClNO9
    Color and Shape:Solid
    Molecular weight:600.15
  • BRP


    <p>BRP, a peptide related to BRINP2, exhibits anti-obesity activity through the activation of FOS. It triggers FOS activation in the central nervous system, and its effect is independent of leptin, GLP-1 receptor, and melanocortin 4 receptor.</p>
    Color and Shape:Odour Solid
  • 5-Methylcytidine 5′-triphosphate

    CAS:
    <p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>
    Formula:C10H18N3O14P3
    Color and Shape:Solid
    Molecular weight:497.18
  • Garenoxacin

    CAS:
    <p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>
    Formula:C23H20F2N2O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.41
  • Ditercalinium chloride

    CAS:
    <p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>
    Formula:C46H50Cl2N6O2
    Color and Shape:Solid
    Molecular weight:789.83
  • 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine

    CAS:
    <p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>
    Formula:C22H31N3O5Si
    Color and Shape:Solid
    Molecular weight:445.58
  • HDAC-IN-85


    <p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>
    Formula:C24H27FN4O5
    Color and Shape:Solid
    Molecular weight:470.49
  • RNA binder 1


    <p>RNA binder 1 (Compound 4b) is an RNA-binding agent capable of crossing the blood-brain barrier. It selectively binds to the G-quadruplex structure of the G4C2 repeat sequence RNA of the C9orf72 gene. This compound significantly reduces levels of the toxic polypeptides poly(GA) and poly(GP) in cells derived from amyotrophic lateral sclerosis (ALS) patients, while it has no significant impact on the antisense polypeptide poly(PR), demonstrating selectivity for sense RNA. RNA binder 1 is useful for studying ALS and frontotemporal dementia (FTD).</p>
    Formula:C22H20N10S2
    Color and Shape:Solid
    Molecular weight:488.13138
  • POLRMT-IN-1


    <p>POLRMT-IN-1 (compound S7) is an inhibitor of POLRMT, specifically utilized in cancer-related research.</p>
    Color and Shape:Odour Solid
  • Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Purity:98.62%
    Color and Shape:Solid
  • N1-Methylpseudouridine-5′-triphosphate tetralithium


    <p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>
    Formula:C10H13Li4N2O15P3
    Color and Shape:Solid
    Molecular weight:521.9
  • Carboxy-pyridostatin

    CAS:
    <p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>
    Formula:C35H34N10O7
    Color and Shape:Solid
    Molecular weight:706.71
  • 5'-O-DMT-ibu-dC

    CAS:
    <p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>
    Formula:C34H37N3O7
    Color and Shape:Solid
    Molecular weight:599.67
  • ML-60218

    CAS:
    <p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>
    Formula:C19H15Cl2N3O2S2
    Purity:98.1%
    Color and Shape:Solid
    Molecular weight:452.38
  • 16,16-dimethyl Prostaglandin A1

    CAS:
    <p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>
    Formula:C22H36O4
    Color and Shape:Solid
    Molecular weight:364.526
  • Chrexanthomycin C


    <p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>
    Formula:C31H24O15
    Color and Shape:Solid
    Molecular weight:636.51
  • PAT-LM1


    <p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>
    Color and Shape:Odour Liquid
  • 5'-O-DMT-Bz-rC

    CAS:
    <p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C37H35N3O8
    Color and Shape:Solid
    Molecular weight:649.69
  • 5-Methylcytidine 5′-triphosphate trisodium


    <p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>
    Formula:C10H15N3Na3O14P3
    Color and Shape:Solid
    Molecular weight:563.13
  • M7G(3'-OMe-5')pppA(2'-OMe)


    <p>M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.</p>
    Formula:C23H33N10O17P3
    Color and Shape:Solid
    Molecular weight:814.49
  • GS-443902 trisodium

    CAS:
    <p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>
    Formula:C12H16N5O13P3·xNa
    Color and Shape:Solid
  • Cytidine 5'-diphosphate trisodium salt

    CAS:
    <p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>
    Formula:C9H15N3Na3O11P2
    Purity:99.55%
    Color and Shape:White Crystalline Powder
    Molecular weight:472.15
  • 5'-O-TBDMS-dA

    CAS:
    <p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>
    Formula:C16H27N5O3Si
    Color and Shape:Solid
    Molecular weight:365.509
  • Nitrosofolic acid

    CAS:
    <p>Nitrosofolic acid is a folic acid derivaive.</p>
    Formula:C19H18N8O7
    Color and Shape:Solid
    Molecular weight:470.40
  • Carboxy pyridostatin trifluoroacetate salt


    <p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>
    Formula:C37H35F3N10O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:820.73
  • CTP Synthetase-IN-1 Ammonium salt


    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Formula:C20H22F3N7O3S2
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:529.56
  • RNA splicing modulator 1

    CAS:
    <p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>
    Formula:C19H20N6OS
    Color and Shape:Solid
    Molecular weight:380.47
  • Lorutengitide

    CAS:
    <p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>
    Formula:C30H50N8O12
    Color and Shape:Solid
    Molecular weight:714.764
  • Xanthosine-5'-Triphosphate

    CAS:
    <p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>
    Formula:C10H15N4O15P3
    Color and Shape:Solid
    Molecular weight:524.164
  • CSN5-IN-2


    <p>CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.</p>
    Color and Shape:Odour Solid
  • Pseudorabies virus-IN-1


    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Color and Shape:Solid
    Molecular weight:508.947