HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 506 products of "HIV Protease"
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GSK3532795
CAS:GSK3532795: potent oral HIV-1 maturation inhibitor; EC50: 1.9-13 nM for various strains.Formula:C42H62N2O4SPurity:98%Color and Shape:SolidMolecular weight:691.027-Deaza-2',3'-dideoxyguanosine
CAS:7-Deaza-2',3'-dideoxyguanosine (7-Deaza-ddG) is a 2′,3′-dideoxynucleoside 5′-triphosphate that inhibits HIV-1 reverse transcriptase with a Ki of 25 nM [1].Formula:C11H14N4O3Color and Shape:SolidMolecular weight:250.25HIV-1 integrase inhibitor 3
CAS:HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).Formula:C21H22F2N4O4Purity:98%Color and Shape:SolidMolecular weight:432.42I-XW-053
CAS:I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-Formula:C22H16N2O2Purity:99.05%Color and Shape:SolidMolecular weight:340.37XZ426
CAS:XZ426 is a potent integrase strand transfer inhibitor with anti- HIV activity .Formula:C22H24F2N4O4Color and Shape:SolidMolecular weight:446.45BILR-355
CAS:BILR-355 is a reverse transcriptase inhibitor.Formula:C25H23N5O3Purity:98%Color and Shape:SolidMolecular weight:441.48U 89360E
CAS:U 89360E is a peptidic inhibitor.Formula:C28H52N8O6Purity:98%Color and Shape:SolidMolecular weight:596.7612-Bromododecanoic Acid
CAS:12-Bromododecanoic acid, a halogenated derivative of lauric acid, serves in the synthesis of clickable myristic acid derivatives and functions as a model fatty acid ligand for elucidating the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes. This compound, at a concentration of 10 µg/ml, has been shown to diminish virion DNA in the culture supernatant of primary hepatocytes from a duckling model of hepatitis B virus (HBV) infection and exhibits inhibitory activity against HIV replication in CEM-SS T cells with an EC50 value of 38 µM.Formula:C12H23BrO2Color and Shape:SolidMolecular weight:279.218U 104489
CAS:U 104489 (PNU-104489) is a novel specific inhibitor of human immunodeficiency virus 1 (HIV-1), showing effective activity against BHA-P-resistant HIV-1MF.Formula:C26H36N6O3SColor and Shape:SolidMolecular weight:512.67HIV-1 inhibitor-10
CAS:HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor.Formula:C39H54O6Color and Shape:SolidMolecular weight:618.84BMS-561390
CAS:BMS-561390, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C14H12ClF3N2OColor and Shape:SolidMolecular weight:316.71A 77003
CAS:A 77003 is a HIV-1 protease inhibitor. A77003 impairs HIV-1 protease-mediated Gag processing.Formula:C44H58N8O6Color and Shape:SolidMolecular weight:794.98WRNA10
CAS:WRNA10 is a potent binding agent for HIV-1TAR RNA (IC50: 10 μM, CC50: 40 μM).Formula:C25H32N4O4Color and Shape:SolidMolecular weight:452.55Ro 31-8588
CAS:Talviraline (HBY 097) inhibits HIV-1 replication and reduces cell death in various cells and immune cells.Formula:C33H56N4O5Color and Shape:SolidMolecular weight:588.82L-689502
CAS:L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).Formula:C39H51N3O7Purity:98%Color and Shape:SolidMolecular weight:673.84Ulonivirine
CAS:Ulonivirine is an orally active non-nucleoside reverse transcriptase inhibitor that exhibits high antiviral activity and can be used to study HIV-1 infection.Formula:C18H8ClF6N5O3Color and Shape:SolidMolecular weight:491.73DGKα-IN-8
CAS:DGKα-IN-8 (Example 51) is a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibiting an IC50 of 22.491 nM and an EC50 of 0.256 nM.Formula:C23H19ClF3N5OColor and Shape:SolidMolecular weight:473.88Reverse transcriptase-IN-1
CAS:Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7Formula:C25H17N7O2Purity:99.61%Color and Shape:SolidMolecular weight:447.45Ref: TM-T12715
1mg64.00€5mg131.00€10mg183.00€25mg311.00€50mg449.00€100mg615.00€200mg833.00€1mL*10mM (DMSO)143.00€Teropavimab
CAS:Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].Color and Shape:LiquidBavtavirine
CAS:Bavtavirine is a non-nucleoside reverse HIV-1 transcriptase inhibitor (NNRTIs),inhibits HIV replication by preventing the transcription of viral RNA into DNA.
Formula:C26H20N6Purity:97.2%Color and Shape:SolidMolecular weight:416.48BMS-955176 HCl
CAS:GSK-3532795: a broader-spectrum HIV-1 maturation inhibitor than bevirimat, effective in vitro and clinically.Formula:C42H62N2O4SColor and Shape:SolidMolecular weight:727.486Azt-pmap
CAS:AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].Formula:C20H25N6O8PPurity:98%Color and Shape:SolidMolecular weight:508.42Berlopentin
CAS:Berlopentin is splenopentin analog used to treat HIV-positive patients. It also has immunostimulatory properties.Formula:C35H55N9O11Color and Shape:SolidMolecular weight:777.86Capravirine
CAS:Capravirine, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C20H20Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:451.37HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFormula:C26H37N3O5SPurity:98%Color and Shape:SolidMolecular weight:503.65Indinavir, threo-
CAS:Indinavir, threo- is a protease inhibitor utilized as a component of highly active antiretroviral treatment to HIV/AIDS.Formula:C36H47N5O4Purity:98%Color and Shape:SolidMolecular weight:613.79HIV-1 protease-IN-8
CAS:HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.Formula:C25H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:489.63A 74704
CAS:A 74704 is a pseudo C2-symmetric inhibitor of HIV-1 protease and its diester analog.Formula:C43H52N4O7Purity:98%Color and Shape:SolidMolecular weight:736.9Droxinavir HCl
CAS:Droxinavir HCl is an antiviral agent and HIV protease inhibitor.Formula:C29H52ClN5O4Purity:98%Color and Shape:SolidMolecular weight:570.22HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Formula:C68H104N10O12SPurity:98%Color and Shape:SolidMolecular weight:1285.68HIV-1 protease-IN-12
CAS:HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-Formula:C25H35N3O5SPurity:98%Color and Shape:SolidMolecular weight:489.63HIV-1 protease-IN-9
CAS:HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and aFormula:C37H41N7O4SPurity:98%Color and Shape:SolidMolecular weight:679.83Palinavir
CAS:Palinavir is an antiviral, it inhibits HIV-1 protease.Formula:C41H52N6O5Purity:98%Color and Shape:SolidMolecular weight:708.89PYR01
CAS:PYR01 is a potent nonnucleoside reverse transcriptase inhibitor of HIV-1 and concurrently acts as a targeted activator to eliminate cells expressing HIV-1 [1].Formula:C21H13F7N4O3Color and Shape:SolidMolecular weight:502.343′-Deoxy Thymidine
CAS:3′-Deoxy Thymidine is a nucleoside analog of thymidine with antiviral activity. 3′-Deoxy Thymidine inhibit HIV replication in peripheral blood mononuclear cells (EC50 = 0.17 µM). 3′-Deoxy Thymidine also decreases plaque formation in CV-1 cells infected with HSV-1 at micromolar concentrations. These properties support the use of 3′-Deoxy Thymidine in antiviral mechanism studies and nucleoside analog evaluation.Formula:C10H14N2O4Purity:99.89%Color and Shape:SolidMolecular weight:226.23DMP 323
CAS:DMP 323 is a potent inhibitor of HIV-1 protease.Formula:C35H38N2O5Purity:98%Color and Shape:SolidMolecular weight:566.69KNI-272
CAS:Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles.Formula:C33H41N5O6S2Color and Shape:SolidMolecular weight:667.84L 694746
CAS:L 694746 is an inhibitor of HIV-1 protease.Formula:C35H42N2O8Purity:98%Color and Shape:SolidMolecular weight:618.72R 87366
CAS:R 87366 is used as a water-soluble HIV protease inhibitor.Formula:C32H39N7O6Purity:98%Color and Shape:SolidMolecular weight:617.7PNU-103017
CAS:PNU-103017 is an inhibitor of HIV protease.Formula:C28H28N2O5SPurity:98%Color and Shape:SolidMolecular weight:504.6HIV-IN-8
CAS:HIV-IN-8 (Compound 9) acts as an HIV inhibitor, suppressing HIV replication with an effective concentration (EC50) of 13 μg/mL [1].Formula:C36H30O16Color and Shape:SolidMolecular weight:718.61L 687908
CAS:L 687908 is a potent inhibitor of hydroxyethylene-containing HIV protease.Formula:C40H51N5O5Purity:98%Color and Shape:SolidMolecular weight:681.86Rp-dGTPαS
CAS:Rp-dGTPαS, an enantiomer of the dNTPαS nucleotide, serves as the substrate for SAMHD1, a critical regulator of cellular dNTP levels that curtails the replication of viruses (HIV-1, etc.) in CD4+ myeloid lineage and resting T cells. The SAMHD1 tetrameric complex facilitates the hydrolysis of Rp-dGQTPαS into 2'-deoxynucleosides and triphosphates [1].Formula:C10H16N5O12P3SColor and Shape:SolidMolecular weight:523.25Cgp 57813
CAS:CGP 57813 is a lipophilic compound, which can be used as an inhibitor of HIV-1 protease.Formula:C43H58N4O8Color and Shape:SolidMolecular weight:758.94NNRTIs-IN-1
CAS:NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-typeFormula:C28H22N6O3Color and Shape:SolidMolecular weight:490.51HIV-1 inhibitor-3
CAS:HIV-1 inhibitor-3 is an HIV infection inhibitor.Formula:C9H10F2N2O5Purity:98%Color and Shape:SolidMolecular weight:264.18Hinokinin
CAS:Hinokinin (Cubebinolide), a bioactive lignan, exhibits a broad spectrum of pharmacological activities.Formula:C20H18O6Color and Shape:SolidMolecular weight:354.35SW106
CAS:SW106 blocks PTHR1 cAMP signaling, not affecting mutant PTHR1-T410P/H223R.Formula:C16H14F5NO2Color and Shape:SolidMolecular weight:347.28GSK3839919A
CAS:GSK3839919A is a potent allosteric inhibitor of HIV-1 integrase [1].Formula:C36H46ClN3O3Color and Shape:SolidMolecular weight:604.22Hydroxy Darunavir
CAS:Hydroxy darunavir, a metabolite of the HIV-1 protease inhibitor darunavir, is generated through isobutyl aliphatic hydroxylation of darunavir.Formula:C27H37N3O8SColor and Shape:SolidMolecular weight:563.66Fosalvudine tidoxil
CAS:Fosalvudine tidoxil, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Formula:C35H64FN2O8PSPurity:98%Color and Shape:SolidMolecular weight:722.93Murabutide
CAS:Murabutide, a safe synthetic immunomodulator, diminishes the expression of CD4 and CCR5 receptors and promotes the secretion of high levels of beta-chemokines,Formula:C23H40N4O11Color and Shape:SolidMolecular weight:548.58L-696229
CAS:L-696229: specific HIV-1 RT inhibitor, blocks viral spread in various cells.Formula:C17H18N2O2Purity:98%Color and Shape:SolidMolecular weight:282.34PDDC inhibitor
CAS:PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is an nSMase2 inhibitor.Formula:C27H29N5O4Purity:96.09% - 99.39%Color and Shape:SolidMolecular weight:487.55HIV-1 inhibitor-54
CAS:HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.Formula:C27H30N6O4SPurity:98.05% - 99.39%Color and Shape:SoildMolecular weight:534.63HIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.Formula:C27H31FN2O6SColor and Shape:SolidMolecular weight:530.61ATPase-IN-6
CAS:ATPase-IN-6 is an inhibitor of H+/K+-ATPase (ATPase) and a derivative of imidazopyridine. It exhibits significant antiviral activity against various viruses, such as HIV-1 and SARS-CoV-2. ATPase-IN-6 is applicable in antiviral infection research.Formula:C29H25N3O4SColor and Shape:SolidMolecular weight:511.59Telinavir
CAS:Telinavir (SC-52151) is a potent and selective inhibitor of HIV protease. It effectively inhibits both HIV-1 and HIV-2, as well as lymphotropic, monocytotropic strains, and wild isolates of simian immunodeficiency viruses, with an EC50 of 26 ng/mL (43 nM). Telinavir shows high protein binding in human plasma and a low distribution rate in red blood cells.Formula:C33H44N6O5Color and Shape:SolidMolecular weight:604.74HIV-1 inhibitor-82
CAS:HIV-1inhibitor-82 (Compound L14) is a small molecule inhibitor of HIV-1 entry with oral bioavailability, exhibiting an IC50 value of 0.39 μM. It holds potential for research in combating HIV-1 infection.Formula:C37H37ClN2O6S2Color and Shape:SolidMolecular weight:705.28A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Formula:C44H58N8O6Purity:98%Color and Shape:SolidMolecular weight:794.98Lentiginosine
CAS:Lentiginosine is a selective amyloglucosidase inhibitor.Formula:C8H15NO2Color and Shape:SolidMolecular weight:157.21Saphenamycin
CAS:Saphenamycin is an antibiotic from a strain of Streptomyces.Formula:C23H18N2O5Purity:98%Color and Shape:SolidMolecular weight:402.40Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Formula:C8H11N3O3SPurity:98%Color and Shape:SolidMolecular weight:229.26HIV-1 inhibitor-61
CAS:HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].Formula:C24H24F2N2O2SColor and Shape:SolidMolecular weight:442.52HIV-1 inhibitor-40
HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.Formula:C25H18N6O2Color and Shape:SolidMolecular weight:434.45Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Formula:C43H67FN2O4SColor and Shape:SolidMolecular weight:727.07GS-9822
CAS:GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.Formula:C36H39ClN4O4SColor and Shape:SolidMolecular weight:659.24HIV-1 inhibitor-52
CAS:HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.Formula:C46H72FNO5SColor and Shape:SolidMolecular weight:770.13HIV-1 inhibitor-18
HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).Formula:C27H31N3O6SColor and Shape:SolidMolecular weight:525.62GSK3739936
CAS:GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.Formula:C34H43FN2O4Color and Shape:SolidMolecular weight:562.71L-697639
CAS:L-697639 inhibits of HIV-1 reverse transcriptase and HIV-1 replication.Formula:C18H21N3O2Color and Shape:SolidMolecular weight:311.38HIV-1 inhibitor-44
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).Formula:C23H26N2O4SColor and Shape:SolidMolecular weight:426.53Integrase-LEDGF/p75 allosteric inhibitor 1
CAS:Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).Formula:C33H41NO6SColor and Shape:SolidMolecular weight:579.75HIV-1-IN-86
CAS:HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Formula:C20H17N3O7SColor and Shape:SolidMolecular weight:443.43HIV-1 inhibitor-13
HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).Formula:C30H32N6O3Color and Shape:SolidMolecular weight:524.61HIV-1 inhibitor-14
HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.Formula:C29H32N6O4SColor and Shape:SolidMolecular weight:560.67HIV-IN-3
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.Formula:C21H32ClN7O3Color and Shape:SolidMolecular weight:465.98HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Formula:C25H21N5OSColor and Shape:SolidMolecular weight:439.53HIV-1 inhibitor-17
HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).Formula:C32H32N4O5SColor and Shape:SolidMolecular weight:584.69NBD-14189
CAS:NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).Formula:C18H16F4N4O2SColor and Shape:SolidMolecular weight:428.40BRD-K98645985
CAS:BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Formula:C33H43N5O4Purity:98%Color and Shape:SolidMolecular weight:573.73ZK-316
CAS:ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.Formula:C27H22D6N6O3S2Color and Shape:SolidMolecular weight:554.72BMIM-TFSI
CAS:BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.Formula:C10H15F6N3O4S2Color and Shape:SolidMolecular weight:419.364(S)-Batylalcohol
CAS:(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.Formula:C21H44O3Color and Shape:SolidMolecular weight:344.572Gardiquimod hydrochloride
CAS:Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formula:C17H24ClN5OColor and Shape:SolidMolecular weight:349.858BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Formula:C29H26N6O5SColor and Shape:SolidMolecular weight:570.6194'-Ethynyl-2'-deoxyadenosine
CAS:4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formula:C12H13N5O3Purity:98%Color and Shape:SolidMolecular weight:275.26ZLM-66
ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.Color and Shape:SolidHIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Formula:C16H15F2N3OSColor and Shape:SolidMolecular weight:335.37Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19BI-2540
CAS:BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .Formula:C24H15ClF5NO5Color and Shape:SolidMolecular weight:527.83NNRT-IN-2
CAS:NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].Formula:C19H14F3N5O3Molecular weight:417.34BI 224436
CAS:BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.Formula:C27H26N2O4Color and Shape:SolidMolecular weight:442.51L 702007
CAS:L 702007 is an inhibitor of HIV-1 reverse transcriptase.Formula:C18H25N3O2Purity:98%Color and Shape:SolidMolecular weight:315.41Desthiazolylmethyl ritonavir
CAS:Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.Formula:C33H43N5O4SColor and Shape:SolidMolecular weight:605.791NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Formula:C20H25ClN4O3SPurity:98%Color and Shape:SolidMolecular weight:436.96Methyl piperazine-2-carboxylate
CAS:Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.Formula:C6H12N2O2Color and Shape:SolidMolecular weight:144.172PD 134922
CAS:PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.Formula:C37H61N5O7SPurity:98%Color and Shape:SolidMolecular weight:719.97MIV-150
CAS:MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formula:C19H17FN4O3Purity:98%Color and Shape:SolidMolecular weight:368.36DPC 684
CAS:DPC 684 is a potent and selective HIV-1 protease inhibitor with an IC90 of 5.7-40 nM and a Ki of 0.021 nM. It competitively inhibits HIV-1 protease, preventing viral polyprotein cleavage. Compared to cellular proteases, DPC 684 shows high selectivity for retroviral proteases. The compound exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant HIV-1 proteases, with an IC90 of 1.9-6.3 nM. DPC 684 is significant for HIV research.Formula:C35H48FN5O5SColor and Shape:SolidMolecular weight:669.85
