HIV Protease
HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.
Found 475 products for "HIV Protease".
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Pepstatin
CAS:Pepstatin (Pepsin Inhibitor S 735A) is a specific and orally aspartate protease inhibitor that also inhibits HIV protease activity. Cost effective and quality assured.Formula:C34H63N5O9Purity:96.74% - 99.94%Color and Shape:SolidMolecular weight:685.89(Rac)-Telinavir
CAS:N1 compound with anti-HIV activity; contains dimethyl, phenyl, quinoline groups.
Formula:C33H44N6O5Purity:99.30%Color and Shape:SolidMolecular weight:604.74GSK2838232
CAS:GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates,GSK2838232 is novel human immune virus (HIV) maturation inhibitor.Formula:C48H73ClN2O6Purity:97.97%Color and Shape:SolidMolecular weight:809.56Ref: TM-T15436
1mg56.00€5mg118.00€1mL*10mM (DMSO)170.00€10mg178.00€25mg375.00€50mg528.00€100mg737.00€Nevirapine
CAS:Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor.Formula:C15H14N4OPurity:99.58% - 99.59%Color and Shape:SolidMolecular weight:266.30(S)-(+)-N-3-Benzylnirvanol
CAS:(S)-(+)-N-3-Benzylnirvanol is a cytochrome P450 CYP2C19 inhibitor with a ki value of 82.5μM for CYP2C9 and 0.25μM for CYP2C19.Cost-effective and quality-assured.Formula:C18H18N2O2Purity:98.90%Color and Shape:White SolidMolecular weight:294.35Salicylanilide
CAS:Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.Formula:C13H11NO2Purity:99.55%Color and Shape:SolidMolecular weight:213.23Ibalizumab
CAS:Ibalizumab(TMB-355) is a humanized IgG4 monoclonal antibody that acts as a CD4 receptor inhibitor, blocking the entry of HIV-1 into cells by binding to the CD4Purity:SDS-PAGE:96.4%;SEC-HPLC:97.7%Color and Shape:Transparent LiquidMolecular weight:147.3 kDaRitonavir
CAS:Ritonavir (ABT 538) inhibits HIV-1/2 proteases; serum proteins limit it but it enhances other HIV drugs by hindering P450 degradation.Formula:C37H48N6O5S2Purity:99.38% - 99.96%Color and Shape:White SolidMolecular weight:720.94Ref: TM-T1525
5mg34.00€10mg50.00€1mL*10mM (DMSO)50.00€25mg74.00€50mg96.00€100mg138.00€200mg192.00€500mg321.00€1g475.00€PF-3450074
CAS:PF-3450074 (PF-74) is a specific HIV-1 inhibitor, blocking viral replication and uncoating at submicromolar EC50=8-640 nM.Formula:C27H27N3O2Purity:98.57%Color and Shape:SolidMolecular weight:425.52Sodium copper chlorophyllin B
CAS:Sodium copper chlorophyllin B exerts antiviral activities against Influenza virus and HIV.Formula:C34H29CuN4Na3O7Purity:≥98%Color and Shape:SolidMolecular weight:738.13Elsulfavirine
CAS:Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.Formula:C24H17BrCl2FN3O5SPurity:99.66%Color and Shape:SolidMolecular weight:629.28Ref: TM-T15210
1mg69.00€5mg147.00€1mL*10mM (DMSO)200.00€10mg230.00€25mg462.00€50mg692.00€100mg973.00€Atazanavir sulfate
CAS:Atazanavir sulfate, an azapeptide HIV-protease inhibitor, treats HIV/AIDS alongside other anti-HIV drugs.Formula:C38H52N6O7·H2SO4Purity:99.31% - 99.40%Color and Shape:SolidMolecular weight:802.93Ref: TM-T0100
5mg44.00€1mL*10mM (DMSO)50.00€10mg58.00€25mg90.00€50mg114.00€100mg170.00€200mg250.00€500mg425.00€Clathrin-IN-1
CAS:Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.Formula:C20H13BrN2O3S2Purity:99.53%Color and Shape:SolidMolecular weight:473.36Ref: TM-T9063
1mg50.00€2mg73.00€5mg90.00€1mL*10mM (DMSO)105.00€10mg141.00€25mg245.00€50mg358.00€100mg530.00€500mg1,153.00€Dolutegravir intermediate-1
CAS:Dolutegravir intermediate-1 is a synthetic precursor for HIV-1 treatment from patent WO 2016125192 A2.Formula:C13H17NO8Purity:99.52%Color and Shape:SolidMolecular weight:315.28Fostemsavir Tris
CAS:Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment.Formula:C29H37N8O11PPurity:99.45%Color and Shape:SolidMolecular weight:704.62Ref: TM-T10570
1mg54.00€5mg114.00€10mg167.00€1mL*10mM (DMSO)170.00€25mg268.00€50mg409.00€100mg580.00€Benfotiamine
CAS:Benfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1), used as an antioxidant dietary supplement.Formula:C19H23N4O6PSPurity:99.2% - 99.91%Color and Shape:White SolidMolecular weight:466.45Atazanavir
CAS:Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.Formula:C38H52N6O7Purity:98% - 99.95%Color and Shape:SolidMolecular weight:704.86NBD-556
CAS:NBD-556 is a small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.Formula:C17H24ClN3O2Purity:99.79%Color and Shape:SolidMolecular weight:337.84TERT-IN-1
CAS:TERT-IN-1 has anti-HIV activity and can be used to study HIV infection.Formula:C16H20ClN3SPurity:99.31%Color and Shape:Yellow SolidMolecular weight:321.87HIV p17 Gag (77-85)
CAS:Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Formula:C44H72N10O15Purity:98%Color and Shape:SolidMolecular weight:981.1ELDKWA
CAS:ELDKWA, a highly conserved sequence of amino acids located on the ecto-domain of gp41, serves as the epitope for mAb 2F5, a neutralizing monoclonal antibodyFormula:C35H52N8O11Color and Shape:SolidMolecular weight:760.83HIV-1 inhibitor-58
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-typeFormula:C26H24N6O2Color and Shape:SolidMolecular weight:452.51Clavirolide L
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 withoutFormula:C20H28O3Color and Shape:SolidMolecular weight:316.43NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Formula:C32H31N9O3SColor and Shape:SolidMolecular weight:621.7112-Oxocalanolide A
12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.Formula:C22H24O5Color and Shape:SolidMolecular weight:368.429HIV gag peptide (197-205)
CAS:HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETIFormula:C45H81N11O14S2Purity:98%Color and Shape:SolidMolecular weight:1064.32TAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Formula:C65H124N34O15Purity:98%Color and Shape:SolidMolecular weight:1621.91IC-1k
IC-1k is an effective inhibitor of HIV-1, exhibiting anti-viral activity with EC50 values of 2.69 nM against HIV-1IIIB and 97.97 nM against HIV-2 ROD. Additionally, IC-1k has been noted to possess cytotoxic properties.Formula:C27H22F2N4O3SColor and Shape:SolidMolecular weight:520.55HIV-1 inhibitor-81
HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.Formula:C32H44N2O8SColor and Shape:SolidMolecular weight:616.77HIV-1 inhibitor-74
HIV-1inhibitor-74 (compound 10c) is a potent inhibitor of HIV-1, displaying an EC50 of 0.0047 µM against HIV-1IIIB. It exhibits cytotoxic properties and effectively inhibits the activity of WTHIV-1RT with an IC50 of 0.134 µM. Additionally, HIV-1inhibitor-74 demonstrates broad-spectrum anti-HIV-1 activity.Formula:C28H31N9O2SColor and Shape:SolidMolecular weight:557.67Delavirdine
CAS:Delavirdine, an NNRTI for HIV-1, is used in HAART.Formula:C22H28N6O3SColor and Shape:SolidMolecular weight:456.56HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Color and Shape:Odour SolidGLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Formula:C102H194N40O20Purity:98%Color and Shape:SolidMolecular weight:2300.89HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Formula:C42H36ClF10N7O5S2Color and Shape:SolidMolecular weight:1008.35L 754394
CAS:L 754394 is an effective and specific inhibitor of the HIV-1 protease.Formula:C38H47N5O5Color and Shape:SolidMolecular weight:653.81MPG, HIV related
CAS:MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Formula:C126H201N35O33SPurity:98%Color and Shape:SolidMolecular weight:2766.22Bictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Formula:C21H17F3N3NaO5Purity:99.97%Color and Shape:SolidMolecular weight:471.36GRL-07524
GRL-07524 (Compound 4e) is a potent HIV-1 protease inhibitor with a Ki of 0.22 nM. It contains an oxaspirocarbamate as the P2 ligand and demonstrates strong antiviral activity, with an EC50 of 210 nM. GRL-07524 can bind to the active site of HIV-1PR and crucial catalytic residues, interacting with one of four symmetric-independent molecules.Color and Shape:Odour SolidHIV-1 inhibitor-59
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.Formula:C28H28FN5O3SColor and Shape:SolidMolecular weight:533.62Globotriaosylceramides (porcine)
CAS:Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Formula:C60H113NO18Color and Shape:SolidMolecular weight:1136.553HIV-1-IN-83
HIV-1-IN-83 (Compound 18E) is a non-nucleoside reverse transcriptase inhibitor targeting HIV-1. It demonstrates an IC50 of 0.45 μM against wild-type HIV-1 reverse transcriptase. HIV-1-IN-83 exhibits potent antiviral activity against both wild-type and mutant HIV-1 strains and enhances drug resistance in Y188L and RES056 mutants. The compound is non-toxic up to a concentration of 11.088 μM.Color and Shape:Odour SolidBNM-III-170
CAS:BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.Formula:C25H26ClF7N6O6Color and Shape:SolidMolecular weight:674.96HIV-1 inhibitor-79
HIV-1inhibitor-79 (Compound 3k) is an HIV inhibitor that demonstrates significant inhibitory activity against HIV-1 and its common mutants, with IC50 values of 1.9 nM for HIV-1, K103, 8.7 nM for L100I, and 11 nM for E138K. It exhibits low cytotoxicity and a high selectivity index (CC50 = 21.95 μM, SI = 11478). Additionally, HIV-1inhibitor-79 shows antiviral activity against HIV-2, with an EC50 value of 6.14 μM, and effectively inhibits HIV-1 reverse transcriptase with an IC50 of 25 nM.Formula:C21H17N7OMolecular weight:383.41Cys-TAT(47-57)
CAS:Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.Formula:C67H124N34O14SPurity:98%Color and Shape:SolidMolecular weight:1661.99AL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFormula:C67H57N7O23Color and Shape:SolidMolecular weight:1328.2Carbovir triphosphate
CAS:Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].Formula:C11H16N5O11P3Color and Shape:SolidMolecular weight:487.19HIV-IN-12
HIV-IN-12 (Compound A1) is a dual inhibitor targeting both HIV-1 Vif and reverse transcriptase (RT). It shows potential for use in HIV infection research.F9170 TFA
F9170, an antiviral peptide derived from the HIV-1 envelope glycoprotein (amino acids 789-803), targets the LLP1 domain in the virus's envelope proteinFormula:C100H135N21O22·XCF3COOHMolecular weight:1983.30NNRT-IN-11
NNRT-IN-11 (14l) is a potent non-nucleoside reverse transcriptase (NNRT) inhibitor, exhibiting EC50 values ranging from 6.50 to 52.9 nM against both wild-type (WT) and a range of HIV-1 mutant strains. NNRT-IN-11 demonstrates antiviral properties.Color and Shape:Odour SolidHIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormula:C23H40O5Purity:98%Color and Shape:SolidMolecular weight:396.56
