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HIV Protease

HIV Protease

HIV Protease inhibitors are a class of antiretroviral drugs that specifically target the protease enzyme of the Human Immunodeficiency Virus (HIV). By inhibiting this enzyme, these compounds prevent the virus from processing its polyproteins into mature, functional proteins, thereby blocking the production of new infectious virions. HIV Protease inhibitors are a cornerstone of highly active antiretroviral therapy (HAART) used to manage HIV/AIDS. At CymitQuimica, we provide a variety of HIV Protease inhibitors to support your research in HIV treatment, drug resistance, and virology.

Found 447 products of "HIV Protease"

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  • Lopinavir
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    Lopinavir

    CAS:
    <p>Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.</p>
    Formula:C37H48N4O5
    Purity:98% - 99.62%
    Color and Shape:White Crystalline Solid
    Molecular weight:628.8

    Ref: TM-T1623

  • Didanosine
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    Didanosine

    CAS:
    <p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>
    Formula:C10H12N4O3
    Purity:99.64%
    Color and Shape:White Crystalline Powder
    Molecular weight:236.23

    Ref: TM-T2578

  • Rilpivirine
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    Rilpivirine

    CAS:
    <p>Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment</p>
    Formula:C22H18N6
    Purity:97.22% - 98.83%
    Color and Shape:Solid
    Molecular weight:366.42

    Ref: TM-T2330

  • Obefazimod
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    Obefazimod

    CAS:
    <p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>
    Formula:C16H10ClF3N2O
    Purity:99.86%
    Color and Shape:Solid
    Molecular weight:338.71

    Ref: TM-T8311

  • 2,4-Dihydroxypyridine
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    2,4-Dihydroxypyridine

    CAS:
    <p>2,4-Dihydroxypyridine: a pyridine derivative, chelates metals, assesses ion levels, measures enzymatic reactions, and quantifies biomolecules.</p>
    Formula:C5H5NO2
    Purity:97.79%
    Color and Shape:White To Yellow-Beige Crystals Or
    Molecular weight:111.1

    Ref: TM-T7963

  • Dimercaprol
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    Dimercaprol

    CAS:
    <p>Dimercaprol (Dicaptol) is an anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-</p>
    Formula:C3H8OS2
    Purity:98.91% - 99.64%
    Color and Shape:Viscous Oily Liquid
    Molecular weight:124.22

    Ref: TM-T0781

  • Raltegravir potassium
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    Raltegravir potassium

    CAS:
    <p>Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.</p>
    Formula:C20H20FN6O5·K
    Purity:98% - 99.55%
    Color and Shape:Off-White Solid
    Molecular weight:482.51

    Ref: TM-T2239

  • NBD-557
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    NBD-557

    CAS:
    <p>NBD-557 is a potentially HIV-1 inhibitor.</p>
    Formula:C17H24BrN3O2
    Purity:99.52%
    Color and Shape:Solid
    Molecular weight:382.3

    Ref: TM-T7382

  • Raltegravir
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    Raltegravir

    CAS:
    <p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>
    Formula:C20H21FN6O5
    Purity:99.86% - >99.99%
    Color and Shape:Solid
    Molecular weight:444.42

    Ref: TM-T2239L

  • IMB-301
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    IMB-301

    CAS:
    <p>IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.</p>
    Formula:C19H17Cl2FN2O
    Purity:99.72%
    Color and Shape:Solid
    Molecular weight:379.26

    Ref: TM-T9212

  • Lamivudine 13C,15N2
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    Lamivudine 13C,15N2

    CAS:
    <p>Lamivudine 13C,15N2, a BCH-189 impurity, blocks HIV/HBV reverse transcriptase as an NRTI.</p>
    Formula:C8H9N3O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:246.22

    Ref: TM-T11814

  • Nelfinavir
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    Nelfinavir

    CAS:
    <p>Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.</p>
    Formula:C32H45N3O4S
    Purity:98.16% - 99.5%
    Color and Shape:White To Off-White Crystalline Powder
    Molecular weight:567.78

    Ref: TM-T7779

  • CymitQuimica logo
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    Elipovimab

    CAS:
    <p>Elipovimab, a potent and broadly neutralizing antibody against HIV-1, targets and eliminates HIV-infected cells [1].</p>
    Color and Shape:Liquid

    Ref: TM-T77177

  • CymitQuimica logo
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    Semzuvolimab

    CAS:
    <p>Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4/Leu-3 (CD4).</p>
    Color and Shape:Liquid

    Ref: TM-T80621

  • CymitQuimica logo
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    Suvizumab

    CAS:
    <p>Suvizumab (KD-247) is a neutralizing anti-HIV-1 antibody with IC50 values of 0.1-1.0 µg/mL; it lowers viral load and prevents infection.</p>
    Color and Shape:Liquid

    Ref: TM-T76991

  • Antiviral agent 55
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    Antiviral agent 55

    CAS:
    <p>Antiviralagent 55 (Compound 95) is an inhibitor of human immunodeficiency viruses 1 and 2 (HIV1 and HIV2), demonstrating antiviral activity.</p>
    Formula:C21H20N2O4
    Color and Shape:Solid
    Molecular weight:364.39

    Ref: TM-T88222

  • Benzalphthalide
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    Benzalphthalide

    CAS:
    <p>Benzalphthalide (NSC-2824) is a chemical compound with anti-HIV activity.</p>
    Formula:C15H10O2
    Purity:99.94%
    Color and Shape:Pale Yellow To Yellow Crystalline Powder
    Molecular weight:222.24

    Ref: TM-T20489

  • CymitQuimica logo
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    Zinlirvimab

    CAS:
    <p>Zinlirvimab is a humanized IgG1-λ2 monoclonal antibody that neutralizes HIV by targeting the HIV-1 gp120 envelope glycoprotein, specifically the IIIB gp120 V3</p>
    Color and Shape:Liquid

    Ref: TM-T80580

  • Nipamovir
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    Nipamovir

    CAS:
    <p>Nipamovir is a nitroimidazole prodrug that exhibits antiviral activity comparable to SAMT-247 and NS-1040 in cellular assays and a human ex vivo model of HIV infection, with low toxicity. Nipamovir has EC50 values of 3.64±3.28 and 3.23±2.81 μM for CEM-SS/HIV-1RF and hPBMC/HIV-192HT599, respectively [1].</p>
    Formula:C14H15N5O4S
    Color and Shape:Solid
    Molecular weight:349.37

    Ref: TM-T87008

  • Antiviral agent 9
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    Antiviral agent 9

    <p>Antiviral agent 9: EC50 0.006 nM vs HIV-1, 300x more selective than TAF.</p>
    Formula:C38H50N7O8P
    Color and Shape:Solid
    Molecular weight:763.82

    Ref: TM-T72593

  • APOBEC3G-IN-1
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    APOBEC3G-IN-1

    CAS:
    <p>APOBEC3G-IN-1 (MN136.0185) is a targeted APOBEC3G inhibitor with anti-HIV activity for the study of infectious diseases and cancer.</p>
    Formula:C15H11NO3
    Purity:96.54%
    Color and Shape:Solid
    Molecular weight:253.25

    Ref: TM-T72910

  • HIV-IN-6
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    HIV-IN-6

    CAS:
    <p>HIV-IN-6, an anti-HIV agent, blocks replication by targeting SFKs like Hck involved with Nef protein.</p>
    Formula:C20H16N4O3S
    Purity:97.12%
    Color and Shape:Solid
    Molecular weight:392.43

    Ref: TM-T61793

  • HIV-1 inhibitor-49
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    HIV-1 inhibitor-49

    <p>HIV-1 inhibitor-49, an oral HEPT analog, has strong pharmacokinetics, potent reverse transcriptase inhibition (IC50=30nM), and is safe in mice.</p>
    Formula:C21H18F2N2O3S
    Color and Shape:Solid
    Molecular weight:416.44

    Ref: TM-T72563

  • MK-2048
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    MK-2048

    CAS:
    <p>MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.</p>
    Formula:C21H21ClFN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.87

    Ref: TM-T6589

  • HIV-1 inhibitor-22
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    HIV-1 inhibitor-22

    CAS:
    <p>HIV-1 inhibitor-22 effectively blocks HIV-1 RT (IC50=3.63 μM) with low cytotoxicity (CC50 &gt; 227 μM).</p>
    Formula:C30H26N6O3S
    Color and Shape:Solid
    Molecular weight:550.63

    Ref: TM-T63890

  • HIV-1 integrase inhibitor 4
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    HIV-1 integrase inhibitor 4

    CAS:
    <p>HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).</p>
    Formula:C24H20F2N4O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:514.5

    Ref: TM-T11568

  • HIV-1 inhibitor-29
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    HIV-1 inhibitor-29

    CAS:
    <p>HIV-1 inhibitor-29: Blocks HIV-1 IIIB (EC50: 2.18μM), resists F227L/V106A (EC50: 0.974μM), low toxicity (CC50: 211μM), for AIDS research.</p>
    Formula:C30H36N6O5
    Color and Shape:Solid
    Molecular weight:560.64

    Ref: TM-T63962

  • D77
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    D77

    CAS:
    <p>D77 is anti-HIV-1 inhibitor. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).</p>
    Formula:C28H22BrNO7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:596.45

    Ref: TM-T15045

  • HIV-1 inhibitor-34
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    HIV-1 inhibitor-34

    CAS:
    <p>HIV-1 inhibitor-34 (5q): potent, selective; EC50: 6.4 nM; MT-4 CC50: 16 μM; useful in AIDS research.</p>
    Formula:C26H27N7O
    Color and Shape:Solid
    Molecular weight:453.54

    Ref: TM-T62782

  • HIV-IN-4
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    HIV-IN-4

    CAS:
    <p>HIV-IN-4 (Compound 12) is a potent HIV inhibitor that exhibits promising anti-HIV activities [1].</p>
    Formula:C14H18N2O3
    Color and Shape:Solid
    Molecular weight:262.3

    Ref: TM-T60426

  • HIV-1 inhibitor-16
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    HIV-1 inhibitor-16

    CAS:
    <p>HIV-1 inhibitor-16: potent with EC50 1.3 nM for wild-type; inhibits K103N, E138K, Y181C, L100I strains; good solubility; stable; low CYP impact; non-toxic.</p>
    Formula:C23H16F2N6
    Color and Shape:Solid
    Molecular weight:414.41

    Ref: TM-T62129

  • HIV-1 inhibitor-57
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    HIV-1 inhibitor-57

    CAS:
    <p>HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50</p>
    Formula:C25H24FN5O3S
    Color and Shape:Solid
    Molecular weight:493.55

    Ref: TM-T78749

  • SARS-CoV-IN-3
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    SARS-CoV-IN-3

    CAS:
    <p>SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor.</p>
    Formula:C25H28ClFeN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477.81

    Ref: TM-T12839

  • Mesoxalic acid
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    Mesoxalic acid

    CAS:
    <p>Mesoxalic acid is a dicarboxylic acid and a ketonic acid which blocks RT translocation.</p>
    Formula:C3H2O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:118.04

    Ref: TM-T25792

  • SAMT-247
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    SAMT-247

    CAS:
    <p>SAMT-247 is an HIV inhibitor that acts by modifying the nucleocapsid NCp7 region of Gag in infected cells and blocking Gag processing and reducing infectivity.</p>
    Formula:C12H14N2O3S
    Color and Shape:Solid
    Molecular weight:266.32

    Ref: TM-T24756

  • TMC310911
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    TMC310911

    CAS:
    <p>TMC310911 is an oral HIV-1 protease inhibitor with an EC50 of 2.2-14.2 nM, effective against various HIV-1 strains.</p>
    Formula:C38H53N5O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:755.99

    Ref: TM-T17106

  • Reverse transcriptase-IN-3
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    Reverse transcriptase-IN-3

    <p>Reverse transcriptase-IN-3, a pyrimidine carboxamide, inhibits HIV-1 including mutant strains.</p>
    Formula:C28H31N7O4S
    Color and Shape:Solid
    Molecular weight:561.66

    Ref: TM-T72203

  • DQBS
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    DQBS

    CAS:
    <p>DQBS is an HIV-1 Nef function antagonist.</p>
    Formula:C22H17ClN4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.91

    Ref: TM-T24017

  • HIV-1 integrase inhibitor 7
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    HIV-1 integrase inhibitor 7

    CAS:
    <p>HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).</p>
    Formula:C30H26O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:642.52

    Ref: TM-T11565

  • β-L-D4A
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    β-L-D4A

    CAS:
    <p>beta-L-D4A inhibits HIV-1 reverse transcriptase, stopping DNA synthesis.</p>
    Formula:C10H11N5O2
    Purity:99.45%
    Color and Shape:Solid
    Molecular weight:233.23

    Ref: TM-FL0097

  • MK-4965
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    MK-4965

    CAS:
    <p>MK-4965 is a new type of non-nucleoside reverse transcriptase inhibitor with antiviral activity.</p>
    Formula:C20H13Cl2N5O2
    Color and Shape:Solid
    Molecular weight:426.26

    Ref: TM-T33435

  • gp120-IN-1
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    gp120-IN-1

    CAS:
    <p>gp120-IN-1 (4e) is a potent HIV-1 inhibitor, IC50 2.2 μM, CC50 100.90 μM, and blocks HIV entry.</p>
    Formula:C15H18N2O4S
    Color and Shape:Solid
    Molecular weight:322.38

    Ref: TM-T60871

  • HIV-1 inhibitor-25
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    HIV-1 inhibitor-25

    CAS:
    <p>Compound R-12a is a potent HIV-1 reverse transcriptase inhibitor (IC50: 0.1061 nM), with low cytotoxicity and effective against multiple mutants.</p>
    Formula:C26H19N5O2
    Color and Shape:Solid
    Molecular weight:433.46

    Ref: TM-T62431

  • LEDGIN6
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    LEDGIN6

    CAS:
    <p>HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.</p>
    Formula:C21H20ClNO2
    Color and Shape:Solid
    Molecular weight:353.84

    Ref: TM-T15483

  • NIT
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    NIT

    CAS:
    <p>NIT is an HIV-1 protease inhibitor.</p>
    Formula:C15H7N3O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:357.36

    Ref: TM-T24536

  • HIV-1 inhibitor-36
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    HIV-1 inhibitor-36

    CAS:
    <p>HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1 inhibitor with significant potential as a novel latency reversing agent [1].</p>
    Formula:C14H14Cl2N2O2S
    Color and Shape:Solid
    Molecular weight:345.24

    Ref: TM-T61134

  • HIV-1 inhibitor-24
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    HIV-1 inhibitor-24

    CAS:
    <p>HIV-1 inhibitor-24 (S-12a) blocks HIV reverse transcription effectively (IC50: 9.5 nM), low toxicity, well-tolerated in mice, good heart safety.</p>
    Formula:C26H19N5O2
    Color and Shape:Solid
    Molecular weight:433.46

    Ref: TM-T62430

  • DPC-681
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    DPC-681

    CAS:
    <p>DPC-681 is a potent and selective HIV protease inhibitor (IC90s: 4 to 40 nM for wild-type HIV-1).</p>
    Formula:C35H48FN5O5S
    Color and Shape:Solid
    Molecular weight:669.85

    Ref: TM-T15163

  • HIV-1 inhibitor-19
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    HIV-1 inhibitor-19

    CAS:
    <p>HIV-1 inhibitor-19 is a potent NNRTI targeting L100I, K103N, V106A/F227L mutants; EC50s: 7.3, 9.2, 21.0 nM respectively.</p>
    Formula:C24H22BClN2O5S
    Color and Shape:Solid
    Molecular weight:496.77

    Ref: TM-T63363

  • HIV-1 inhibitor-15
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    HIV-1 inhibitor-15

    CAS:
    <p>HIV-1 inhibitor-15 (compound 9d): Potent, broad-spectrum, EC50=1.7-9 nM for various strains, good solubility/safety, oral use.</p>
    Formula:C24H20N6
    Color and Shape:Solid
    Molecular weight:392.46

    Ref: TM-T61797