Antibacterial

<p>Fobrepodacin (SPR720) is an orally active and potent phosphate prodrug of SPR719 (VXc-486). Fobrepodacin has potent bactericidal activities in vivo.</p>

<p>PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.</p>

<p>MMV1578877 is an inhibitor of Mycobacterium ulcerans with an IC50 of 0.37 μM. It is applicable in research related to Buruli ulcer (BU).</p>

<p>Eremomycin, an antibiotic, can be used intramuscularly due to low toxicity.</p>

<p>LEAP-2 (Human liver expressed antimicrobial peptide-2) is an antimicrobial peptide, a growth hormone-releasing peptide antagonist, and a GHS-R1a inverse agonist</p>

<p>SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under</p>

<p>(R)-Eucomol, a flavonoid derivative, exhibits slight antibacterial properties and demonstrates cytotoxic activity against KB and P-388 cells [1].</p>

<p>Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.</p>

<p>1-Ethylnaphthalene exhibits antibacterial activity and can be used in biochemical experiments and drug synthesis.</p>

<p>Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.</p>

<p>Efflux pump-IN-3 inhibits AcrB, potentiates antibiotics, and is non-toxic to membranes and nematodes.</p>

<p>Dodicin hydrochloride, an effective disinfectant, demonstrates broad antimicrobial activity [1].</p>

<p>Rose Bengal is a photosensitizer effective against microbial cells. In the presence of light and oxygen, it inhibits the growth of yeast cells and other microorganisms, sometimes leading to their death. Rose Bengal can also limit bacterial growth, restrict the colony size of filamentous fungi, and suppress the growth of "spreading fungi" such as Rhizopus and Trichoderma.</p>

<p>Ibericin, an anthraquinone from Prismatomeris filamentosa roots, exhibits antibacterial effects on Gram-positive and Gram-negative bacteria.</p>

<p>Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.</p>

<p>Alamethicin F50, a 20-amino acid peptaibol from Trichoderma, forms ion channels and has lytic and antibacterial properties.</p>

<p>Mycobactin P is one of iron(III) chelating compounds produced by most species of Mycobacteria which act as growth factors.</p>

<p>Showdomycin is an antibiotic with antineoplastic activity.</p>

<p>LL-37, Human TFA (154947-66-7 free base) is a 37-residue amphipathic helical peptide, the sole human cathelicidin antimicrobial peptide, antibacterial.</p>

<p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>

<p>Dicloxacillin Sodium (BRL1702 Sodium) is a β-lactamase resistant penicillin similar to oxacillin and it has activity against gram-positive/negative bacteria.</p>

<p>LL-37 scrambled peptide is a scrambled version of cathelicidin anti-microbial peptide LL-37.</p>

<p>1-Isothiocyanato-6-(methylsulfenyl)-hexane, identified in wasabi (W. japonica), exhibits multifaceted biological activities. This isothiocyanate compound demonstrates antibacterial properties by inhibiting B. subtilis growth in an agar diffusion assay at 25 µmol/disc, and antifungal effectiveness against T. mentagrophytes with a minimum inhibitory concentration (MIC) of 25 µg/ml. Additionally, it acts as a repellent in the blue mussel (M. edulis) assay and shows antifouling capabilities on polyvinyl chloride (PVC) plates at a concentration of 50 µmol/cm^2, underscoring its potential in biotechnological applications.</p>

<p>Psicofuranine: a nucleoside antibiotic inhibiting GMP synthase and P. falciparum growth with an IC50 of 0.3 mM.</p>

<p>Rubradirin B has an antibacterial activity similar to rubradirin, but the antibiotic is less active.</p>

<p>Polyunsaturated anacardic acid diene from cashew shells fights MRSA, S. mutans, and S. mansoni; inhibits soybean lipoxygenase-1.</p>

<p>Dicloxacillin, a β-Lactam antibiotic, targets beta-lactamase bacteria like Staphylococcus aureus, defeating penicillin resistance.</p>

<p>The compound is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II.</p>

<p>EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.</p>

<p>Olaquindox can be used in relevant research in the life sciences. Its product number is T2779 and CAS number is 23696-28-8.</p>

<p>ACH-702 is an agent of anti-tubercular. ACH-702 is an effective, bactericidal compound with activity against many antibiotic-resistant pathogens.</p>

<p>Nv-CATH, an antibacterial peptide derived from frogs, exhibits broad-spectrum activity against both gram-positive and gram-negative bacteria, and significantly</p>

<p>Faropenem daloxate (Faropenem medoxil) is useful for penem and antibiotics.</p>

<p>Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.</p>

<p>Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH) and a major component of coal tar, serving as an insect repellent in camphor balls</p>

<p>Antibiotic tan-592B is an antibiotic agent.</p>

<p>Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.</p>

<p>Maximin H2, an antimicrobial peptide originating from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits inhibitory effects on a range</p>

<p>RvD4, derived from docosahexaenoic acid, reduces neutrophil infiltration and promotes phagocytosis/clearance by human cells.</p>

<p>SPR206 is a polymyxin analogue and an important class of antibiotic for the treatment of bacterial infections due to multidrug resistant Gram-negative pathogen.</p>

<p>Funalenone, from A. niger, inhibits HIV-1 integrase, HIV replication, and MMP-1, also curbing S. aureus growth. Less toxic to human cells.</p>

<p>Maximin 39, an antimicrobial peptide originating from toad brain, exhibits activity against Staphylococcus aureus and Escherichia coli, demonstrating minimum</p>

<p>Thiotropocin is an antibiotic.</p>

<p>Maximin 3, an antimicrobial peptide originating from the skin secretions of Bombina maxima, exhibits cytotoxicity against tumor cells and possesses spermicidal</p>

<p>Ascr#18: nematode hormone boosts infection resistance in plants like Arabidopsis, tomato, potato, barley.</p>

<p>MBL-IN-1 (compound 41), a β-Lactamase inhibitor, exhibits an IC50 range of 0.10 to 25.85 µM and is utilized in the study of bacterial infections [1].</p>

<p>dmDNA31: a rifamycin antibiotic, inhibits bacterial RNA polymerase, strongly kills Staphylococcus aureus.</p>

<p>Flagelin 22, a bacterial flagellin fragment, serves as a potent elicitor for plants and algae.</p>

<p>Kirromycin, an antibiotic from Streptomyces, blocks protein synthesis and stunts B. brevis growth by hindering elongation factor Tu in E. coli.</p>

<p>Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis.</p>