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PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.

Subcategories of "PI3K/Akt/mTOR Signaling"

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Found 1038 products of "PI3K/Akt/mTOR Signaling"

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  • β-Hydroxyisovalerylshikonin
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    β-Hydroxyisovalerylshikonin

    CAS:
    <p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>
    Formula:C21H24O7
    Purity:98.16%
    Color and Shape:Solid
    Molecular weight:388.41

    Ref: TM-TN1440

  • PP 3
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    PP 3

    CAS:
    <p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>
    Formula:C11H9N5
    Purity:98.61%
    Color and Shape:Whit To Off-White Solid
    Molecular weight:211.22

    Ref: TM-T23176

  • UCB9608
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    UCB9608

    CAS:
    <p>UCB9608 is a selective and orally active PI4KIIIβ inhibitor (IC50: 11 nM), selective over PI3KC2 α, β, and γ lipid kinases.</p>
    Formula:C20H26N8O2
    Purity:97.53% - 99.59%
    Color and Shape:Solid
    Molecular weight:410.47

    Ref: TM-TQ0009

  • ZM39923 hydrochloride
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    ZM39923 hydrochloride

    CAS:
    <p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>
    Formula:C23H25NO·HCl
    Purity:98.05%
    Color and Shape:Solid
    Molecular weight:367.91

    Ref: TM-T6145

  • BpV(HOpic)
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    BpV(HOpic)

    CAS:
    <p>BpV(HOpic) (bpV (HOpic)) is a potent inhibitor of PTEN (IC50 of 14 nM).</p>
    Formula:C6H4K2NO8V
    Purity:99.60%
    Color and Shape:Solid
    Molecular weight:347.24

    Ref: TM-T7953

  • KY19382
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    KY19382

    CAS:
    <p>KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.</p>
    Formula:C17H11Cl2N3O2
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:360.19

    Ref: TM-T9025

  • YKL-05-099
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    YKL-05-099

    CAS:
    <p>YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. It can inhibit the activity of SIK1 and SIK3.Cost-effective and quality-assured.</p>
    Formula:C32H34ClN7O3
    Purity:99.57% - 99.66%
    Color and Shape:Solid
    Molecular weight:600.11

    Ref: TM-T17271

  • Derazantinib dihydrochloride
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    Derazantinib dihydrochloride

    CAS:
    <p>Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.</p>
    Formula:C29H31Cl2FN4O
    Color and Shape:Solid
    Molecular weight:541.49

    Ref: TM-T70143

  • 4-Chloro-2'-bromoacetophenone
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    4-Chloro-2'-bromoacetophenone

    CAS:
    <p>4-Chloro-2'-bromoacetophenone against glycogen synthase kinase-3 (GSK-3beta).</p>
    Formula:C8H6BrClO
    Purity:98.34% - 99.41%
    Color and Shape:White To Beige Solid
    Molecular weight:233.49

    Ref: TM-T8908

  • WHI-P180
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    WHI-P180

    CAS:
    <p>WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.</p>
    Formula:C16H15N3O3
    Purity:99.21%
    Color and Shape:Solid
    Molecular weight:297.31

    Ref: TM-T2032

  • Saracatinib
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    Saracatinib

    CAS:
    <p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>
    Formula:C27H32ClN5O5
    Purity:98% - 99.63%
    Color and Shape:Solid
    Molecular weight:542.03

    Ref: TM-T6078

  • mTOR inhibitor-1
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    mTOR inhibitor-1

    CAS:
    <p>C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.</p>
    Formula:C16H15BrN2O3
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:363.21

    Ref: TM-T5338

  • NIH-12848
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    NIH-12848

    CAS:
    <p>NIH-12848 is a putative inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) with an IC50 of 1 μM.</p>
    Formula:C20H14F3N3S
    Purity:99.84% - 99.9%
    Color and Shape:Solid
    Molecular weight:385.41

    Ref: TM-T3556

  • AMG319
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    AMG319

    CAS:
    <p>AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, &gt;47-fold selectivity over other PI3Ks. Phase 2.</p>
    Formula:C21H16FN7
    Purity:98.9% - 99.24%
    Color and Shape:Crystalline Solid
    Molecular weight:385.4

    Ref: TM-T6757

  • GNE-493
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    GNE-493

    CAS:
    <p>GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for</p>
    Formula:C17H20N6O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:372.44

    Ref: TM-T7166

  • BGT226
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    BGT226

    CAS:
    <p>BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.</p>
    Formula:C28H25F3N6O2
    Purity:95.74% - 99.51%
    Color and Shape:Solid
    Molecular weight:534.53

    Ref: TM-T6072L

  • TAS0728
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    TAS0728

    CAS:
    <p>TAS0728 is a HER2 inhibitor, with antitumor activity</p>
    Formula:C26H32N8O3
    Purity:97.78%
    Color and Shape:Solid
    Molecular weight:504.58

    Ref: TM-T7819

  • PKD-IN-1 dihydrochloride (956121-30-5 free base)
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    PKD-IN-1 dihydrochloride (956121-30-5 free base)

    CAS:
    <p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>
    Formula:C18H21Cl3N4O
    Purity:99.5%
    Color and Shape:Solid
    Molecular weight:415.75

    Ref: TM-T8957L

  • WHI-P154
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    WHI-P154

    CAS:
    <p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>
    Formula:C16H14BrN3O3
    Purity:98% - 99.67%
    Color and Shape:Solid
    Molecular weight:376.2

    Ref: TM-T1985

  • HG-14-10-04
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    HG-14-10-04

    CAS:
    <p>HG-14-10-04 is a potent and specific ALK inhibitor.</p>
    Formula:C29H34ClN7O
    Purity:99.75% - >99.99%
    Color and Shape:Solid
    Molecular weight:532.08

    Ref: TM-T4015