PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
TG 100713
CAS:925705-73-3
TG 100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of …
Formula:
C12H10N6O
Purity:
98.17%
Color and Shape:
Solid
Molecular weight:
254.25
Ref: TM-T6704
| 5mg | 38.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 271.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BEBT-908
CAS:1235449-52-1
BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits …
Formula:
C23H25N9O3S
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
507.57
Ref: TM-T16529
| 1mg | 121.00 € | ||
| 2mg | 170.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 377.00 € | ||
| 25mg | 629.00 € | ||
| 50mg | 897.00 € | ||
| 100mg | 1,214.00 € | ||
| 200mg | 912.00 € | ||
| 500mg | 2,401.00 € | ||
| 1mL*10mM (DMSO) | 278.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3K-IN-1
CAS:1349796-36-6
PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits …
Formula:
C31H29N5O6S
Purity:
97.03% - 98%
Color and Shape:
Solid
Molecular weight:
599.66
Ref: TM-T1826
| 1mg | 35.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 496.00 € | ||
| 500mg | 1,096.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dorsomorphin dihydrochloride
CAS:1219168-18-9
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) …
Formula:
C24H25N5O·2HCl
Purity:
97.74% - 99.89%
Color and Shape:
Solid
Molecular weight:
472.41
Ref: TM-T6146
| 2mg | 36.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 132.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 423.00 € | ||
| 500mg | 916.00 € | ||
| 1mL*10mM (DMSO) | 57.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
VP3.15 dihydrobromide
CAS:1281681-33-1
VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.
Formula:
C20H24Br2N4OS
Purity:
96.68% - ≥95%
Color and Shape:
Solid
Molecular weight:
528.3
Ref: TM-T5956
| 2mg | 46.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 372.00 € | ||
| 100mg | 553.00 € | ||
| 500mg | 1,194.00 € | ||
| 1mL*10mM (DMSO) | 81.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MHY1485
CAS:326914-06-1
MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby …
Formula:
C17H21N7O4
Purity:
100% - 98%
Color and Shape:
Solid
Molecular weight:
387.39
Ref: TM-T1908
| 5mg | 55.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 114.00 € | ||
| 50mg | 182.00 € | ||
| 100mg | 342.00 € | ||
| 200mg | 502.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PS 48
CAS:1180676-32-7
PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). …
Formula:
C17H15ClO2
Purity:
98.37% - ≥95%
Color and Shape:
Solid
Molecular weight:
286.75
Ref: TM-T3163
| 5mg | 51.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 167.00 € | ||
| 100mg | 252.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor-1
CAS:468747-17-3
C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.
Formula:
C16H15BrN2O3
Purity:
100%
Color and Shape:
Solid
Molecular weight:
363.21
Ref: TM-T5338
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 276.00 € | ||
| 100mg | 458.00 € | ||
| 1mL*10mM (DMSO) | 67.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
lavendustin C
CAS:125697-93-0
lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine …
Formula:
C14H13NO5
Purity:
97.77%
Color and Shape:
Yellow To Tan Powder
Molecular weight:
275.26
Ref: TM-T4185
| 1mg | 43.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 158.00 € | ||
| 25mg | 341.00 € | ||
| 50mg | 507.00 € | ||
| 100mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Canertinib
CAS:267243-28-7
Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing …
Formula:
C24H25ClFN5O3
Purity:
100% - 99.18%
Color and Shape:
White Or Similar To White Crystalline Powder
Molecular weight:
485.94
Ref: TM-T6136
| 5mg | 37.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 69.00 € | ||
| 50mg | 86.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3Kδ-IN-15
CAS:1146702-54-6
CAL-101 (Idelalisib) is a selective inhibitor of p110δ; shown to have 40- to 300-fold greater …
Formula:
C21H16FN7O
Purity:
99.39%
Color and Shape:
Solid
Molecular weight:
401.4
Ref: TM-T8651
| 5mg | 35.00 € | ||
| 10mg | 50.00 € | ||
| 25mg | 75.00 € | ||
| 50mg | 96.00 € | ||
| 100mg | 123.00 € | ||
| 200mg | 180.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin 23
CAS:118409-57-7
Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.
Formula:
C10H6N2O2
Purity:
99.19% - 99.7%
Color and Shape:
Yellow-Tan Solid
Molecular weight:
186.17
Ref: TM-T2063
| 10mg | 59.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 333.00 € | ||
| 1mL*10mM (DMSO) | 43.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AS-605240
CAS:648450-29-7
AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).
Formula:
C12H7N3O2S
Purity:
97% - 99.91%
Color and Shape:
Solid
Molecular weight:
257.27
Ref: TM-T2248
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 165.00 € | ||
| 100mg | 229.00 € | ||
| 200mg | 341.00 € | ||
| 500mg | 552.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Tyrphostin AG 879
CAS:148741-30-4
Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher …
Formula:
C18H24N2OS
Purity:
99.05%
Color and Shape:
Solid
Molecular weight:
316.46
Ref: TM-T6712
| 5mg | 50.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 418.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
EGFR-IN-12
CAS:879127-07-8
EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 …
Formula:
C21H18F3N5O
Purity:
98.30% - 99.19%
Color and Shape:
Solid
Molecular weight:
413.4
Ref: TM-T5168
| 1mg | 81.00 € | ||
| 5mg | 156.00 € | ||
| 10mg | 255.00 € | ||
| 25mg | 511.00 € | ||
| 50mg | 727.00 € | ||
| 100mg | 985.00 € | ||
| 500mg | 1,977.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Serabelisib
CAS:1268454-23-4
Serabelisib (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).
Formula:
C19H17N5O3
Purity:
95.12% - 99.5%
Color and Shape:
Solid
Molecular weight:
363.37
Ref: TM-T3153
| 1mg | 44.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 508.00 € | ||
| 500mg | 1,086.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PS210
CAS:1221962-86-2
PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits …
Formula:
C19H15F3O5
Purity:
99.65%
Color and Shape:
Solid
Molecular weight:
380.31
Ref: TM-T16670
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 106.00 € | ||
| 25mg | 195.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 515.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PD168393
CAS:194423-15-9
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, …
Formula:
C17H13BrN4O
Purity:
99.13% - 99.7%
Color and Shape:
Solid
Molecular weight:
369.22
Ref: TM-T6932
| 1mg | 39.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 151.00 € | ||
| 50mg | 219.00 € | ||
| 100mg | 304.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TG100-115
CAS:677297-51-7
TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.
Formula:
C18H14N6O2
Purity:
100% - 98.95%
Color and Shape:
Solid
Molecular weight:
346.34
Ref: TM-T2672
| 1mg | 42.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 581.00 € | ||
| 500mg | 1,189.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NS309
CAS:18711-16-5
NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect …
Formula:
C8H4Cl2N2O2
Purity:
95.87%
Color and Shape:
Solid
Molecular weight:
231.04
Ref: TM-T4612
| 5mg | 57.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 214.00 € | ||
| 100mg | 318.00 € | ||
| 200mg | 465.00 € | ||
| 500mg | 734.00 € | ||
| 1mL*10mM (DMSO) | 62.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
