PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
PD-161570
CAS:192705-80-9
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 …
Formula:
C26H35Cl2N7O
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
532.51
Ref: TM-T23127
| 1mg | 36.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 295.00 € | ||
| 50mg | 473.00 € | ||
| 100mg | 673.00 € | ||
| 200mg | 926.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Lazertinib
CAS:1903008-80-9
Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.
Formula:
C30H34N8O3
Purity:
98.7% - 99.53%
Color and Shape:
Solid
Molecular weight:
554.64
Ref: TM-T4485
| 1mg | 48.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 147.00 € | ||
| 25mg | 235.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 462.00 € | ||
| 500mg | 1,072.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
β-Hydroxyisovalerylshikonin
CAS:7415-78-3
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been …
Formula:
C21H24O7
Purity:
98.16%
Color and Shape:
Solid
Molecular weight:
388.41
Ref: TM-TN1440
| 1mg | 134.00 € | ||
| 5mg | 395.00 € | ||
| 10mg | 575.00 € | ||
| 25mg | 894.00 € | ||
| 50mg | 1,199.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dorsomorphin
CAS:866405-64-3
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.
Formula:
C24H25N5O
Purity:
98% - 99.3%
Color and Shape:
Solid
Molecular weight:
399.49
Ref: TM-T1977
| 5mg | 52.00 € | ||
| 10mg | 80.00 € | ||
| 25mg | 139.00 € | ||
| 50mg | 232.00 € | ||
| 100mg | 417.00 € | ||
| 200mg | 447.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GSK-3β inhibitor 10
CAS:1198098-03-1
GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.
Formula:
C12H12N2O3S
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
264.3
Ref: TM-T9725
| 2mg | 38.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 169.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 362.00 € | ||
| 200mg | 506.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD2858
CAS:486424-20-8
AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating …
Formula:
C21H23N7O3S
Purity:
98% - 99.25%
Color and Shape:
Solid
Molecular weight:
453.52
Ref: TM-T1957
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 194.00 € | ||
| 50mg | 365.00 € | ||
| 100mg | 544.00 € | ||
| 500mg | 1,180.00 € | ||
| 1mL*10mM (DMSO) | 108.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Brigatinib
CAS:1197953-54-0
Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
Formula:
C29H39ClN7O2P
Purity:
100% - 99.93%
Color and Shape:
Solid
Molecular weight:
584.09
Ref: TM-T3621
| 2mg | 36.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 112.00 € | ||
| 100mg | 163.00 € | ||
| 200mg | 235.00 € | ||
| 500mg | 400.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MAZ51
CAS:163655-37-6
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
Formula:
C21H18N2O
Purity:
98.53%
Color and Shape:
Solid
Molecular weight:
314.38
Ref: TM-T8496
| 1mg | 40.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 126.00 € | ||
| 25mg | 242.00 € | ||
| 50mg | 403.00 € | ||
| 100mg | 599.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Gefitinib-based PROTAC 3
CAS:2230821-27-7
Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).
Formula:
C47H57ClFN7O8S
Purity:
97.29% - 98.25%
Color and Shape:
Solid
Molecular weight:
934.51
Ref: TM-T5437
| 2mg | 44.00 € | ||
| 5mg | 61.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 248.00 € | ||
| 100mg | 358.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dacomitinib hydrate
CAS:1042385-75-0
Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal …
Formula:
C24H27ClFN5O3
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
487.96
Ref: TM-T19965
| 5mg | 50.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 102.00 € | ||
| 50mg | 136.00 € | ||
| 100mg | 204.00 € | ||
| 200mg | 301.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Almonertinib
CAS:1899921-05-1
Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, …
Formula:
C30H35N7O2
Purity:
99.99%
Color and Shape:
Solid
Molecular weight:
525.64
Ref: TM-T5462
| 1mg | 88.00 € | ||
| 5mg | 193.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 514.00 € | ||
| 50mg | 739.00 € | ||
| 100mg | 1,016.00 € | ||
| 500mg | 2,070.00 € | ||
| 1mL*10mM (DMSO) | 248.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD-7648
CAS:2230820-11-6
AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM …
Formula:
C18H20N8O2
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
380.4
Ref: TM-T7122
| 1mg | 40.00 € | ||
| 5mg | 86.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 306.00 € | ||
| 100mg | 462.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TAS6417
CAS:1661854-97-2
Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective …
Formula:
C23H20N6O
Purity:
99.19%
Color and Shape:
Solid
Molecular weight:
396.44
Ref: TM-T16996
| 1mg | 96.00 € | ||
| 2mg | 122.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 305.00 € | ||
| 25mg | 616.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,513.00 € | ||
| 500mg | 3,045.00 € | ||
| 1mL*10mM (DMSO) | 214.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RGB-286638 free base
CAS:784210-88-4
RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.
Formula:
C29H35N7O4
Purity:
97.29% - 99.91%
Color and Shape:
Solid
Molecular weight:
545.63
Ref: TM-T2378
| 1mg | 46.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 144.00 € | ||
| 25mg | 263.00 € | ||
| 50mg | 396.00 € | ||
| 100mg | 554.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
GDC-0326
CAS:1282514-88-8
GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).
Formula:
C19H22N6O3
Purity:
100% - 99.35%
Color and Shape:
Solid
Molecular weight:
382.42
Ref: TM-T3985
| 1mg | 36.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 585.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
G5-7
CAS:939681-36-4
G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.
Formula:
C22H19F2NO3
Purity:
97.30%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T8742
| 1mg | 49.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 360.00 € | ||
| 100mg | 505.00 € | ||
| 200mg | 685.00 € | ||
| 1mL*10mM (DMSO) | 102.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Osimertinib mesylate
CAS:1421373-66-1
Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective …
Formula:
C29H37N7O5S
Purity:
100% - 99.53%
Color and Shape:
Solid
Molecular weight:
595.71
Ref: TM-T3634
| 1g | 149.00 € | ||
| 5mg | 49.00 € | ||
| 10mg | 60.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 94.00 € | ||
| 200mg | 111.00 € | ||
| 500mg | 129.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TMBIM6 antagonist-1
CAS:123134-61-2
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor
Formula:
C15H12N2O3
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
268.27
Ref: TM-T8649
| 1mg | 92.00 € | ||
| 2mg | 119.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 312.00 € | ||
| 25mg | 560.00 € | ||
| 50mg | 799.00 € | ||
| 100mg | 1,098.00 € | ||
| 500mg | 2,183.00 € | ||
| 1mL*10mM (DMSO) | 199.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NIBR-17
CAS:944396-88-7
NIBR-17 is a pan class I PI3K inhibitor. NIBR-17 inhibits PI3KKα, PI3KKβ, PI3KKγ, and PI3KKδ …
Formula:
C18H20N8O2
Purity:
97.79%
Color and Shape:
Solid
Molecular weight:
380.4
Ref: TM-T22377
| 1mg | 181.00 € | ||
| 5mg | 367.00 € | ||
| 10mg | 546.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
RG14620
CAS:136831-49-7
RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.
Formula:
C14H8Cl2N2
Purity:
99.56% - 99.79%
Color and Shape:
Solid
Molecular weight:
275.13
Ref: TM-T3554
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 76.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 256.00 € | ||
| 100mg | 427.00 € | ||
| 500mg | 920.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
