PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
O-Desmethyl gefitinib
CAS:847949-49-9
O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed …
Formula:
C21H22ClFN4O3
Purity:
99.6%
Color and Shape:
Solid
Molecular weight:
432.88
Ref: TM-T16369
| 1mg | 56.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 343.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 783.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Monday 3 Mar 2025
Chamigrenal
CAS:19912-84-6
β-Chamigrenal: Anti-inflammatory, inhibits NO and PGE2 in macrophages, PAF antagonist (IC50=1.2x10^-4 M), weakly cytotoxic to …
Formula:
C15H22O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
218.33
Ref: TM-T3P2855
| 1mg | 88.00 € | ||
| 5mg | 351.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
EGFR-IN-76
CAS:2607829-38-7
EGFR-IN-76 is a potent EGFR inhibitor.
Formula:
C30H30ClFN6O2
Purity:
97.02% - 97.72%
Color and Shape:
Liquid
Molecular weight:
561.05
Ref: TM-T75120
| 1mg | 124.00 € | ||
| 5mg | 298.00 € | ||
| 10mg | 472.00 € | ||
| 25mg | 905.00 € | ||
| 50mg | 1,454.00 € | ||
| 100mg | 1,977.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Sonolisib
CAS:502632-66-8
Sonolisib is an irreversible and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), …
Formula:
C29H35NO8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
525.59
Ref: TM-T16908
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
CDK8-IN-12
CAS:2613307-67-6
CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell …
Formula:
C21H20ClN3O2
Purity:
98.97% - 99.83%
Color and Shape:
Soild
Molecular weight:
381.86
Ref: TM-T72048
| 1mg | 52.00 € | ||
| 5mg | 101.00 € | ||
| 10mg | 150.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 363.00 € | ||
| 100mg | 509.00 € | ||
| 200mg | 695.00 € | ||
| 1mL*10mM (DMSO) | 116.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Cisapride hydrate
CAS:260779-88-2
Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of …
Formula:
C23H31ClFN3O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
483.96
Ref: TM-T22296
| 500mg | 555.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
WAY-270360
CAS:476633-98-4
WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.
Formula:
C22H19N3O3
Purity:
98.66%
Color and Shape:
Liquid
Molecular weight:
373.4
Ref: TM-T60064
| 1mg | 64.00 € | ||
| 5mg | 139.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 331.00 € | ||
| 50mg | 465.00 € | ||
| 100mg | 655.00 € | ||
| 500mg | 1,301.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
GSK251
CAS:2125968-05-8
GSK251 is a novel, orally bioavailable inhibitor of PI3Kδ, exhibiting high potency and selectivity, with …
Formula:
C29H37FN6O4S
Purity:
98.9%
Color and Shape:
Solid
Molecular weight:
584.71
Ref: TM-T39573
| 1mg | 163.00 € | ||
| 5mg | 396.00 € | ||
| 10mg | 562.00 € | ||
| 25mg | 837.00 € | ||
| 50mg | 1,121.00 € | ||
| 100mg | 1,520.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Astragaloside VI
CAS:84687-45-6
Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.
Formula:
C47H78O19
Purity:
98%
Color and Shape:
Solid
Molecular weight:
947.122
Ref: TM-T13559
| 10mg | 568.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Duvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor.
Formula:
C22H18Cl2N6O
Purity:
99.76% - 99.87%
Color and Shape:
Soild
Molecular weight:
453.32
Ref: TM-T11129L
| 1mg | 313.00 € | ||
| 5mg | 758.00 € | ||
| 10mg | 1,035.00 € | ||
| 25mg | 1,568.00 € | ||
| 50mg | 2,118.00 € | ||
| 100mg | 2,783.00 € | ||
| 1mL*10mM (DMSO) | 945.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
ARRY-380 (analog )
CAS:937265-83-3
ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.
Formula:
C29H27N7O4S
Purity:
98.22%
Color and Shape:
Solid
Molecular weight:
569.63
Ref: TM-T2518
| 1mg | 35.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 110.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 266.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
EGFR/PI3Kα-IN-1
EGFR/PI3Kα-IN-1 (compound 30k), a dual EGFR/PI3Kα inhibitor, exhibits potent activity with IC 50 values of …
Formula:
C50H49N11O5S
Color and Shape:
Liquid
Molecular weight:
916.06
Ref: TM-T200282
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of …
Formula:
C15H12N4O2S
Color and Shape:
Liquid
Molecular weight:
312.35
Ref: TM-T200354
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
IHMT-PI3K-315
IHMT-PI3K-315 (20e) serves as a potent, selective inhibitor of PI3Kγ/δ, exhibiting IC 50 values of …
Formula:
C22H20F2N6O4
Color and Shape:
Liquid
Molecular weight:
470.43
Ref: TM-T200165
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Barecetamab
CAS:2275727-74-5
Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.
Color and Shape:
Liquid
Ref: TM-T76918
| 1mg | 311.00 € | ||
| 5mg | 1,008.00 € | ||
| 10mg | 1,359.00 € | ||
| 25mg | 2,015.00 € | ||
| 50mg | 2,717.00 € | ||
| 100mg | 3,668.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Intetumumab
CAS:725735-28-4
Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for …
Color and Shape:
Liquid
Molecular weight:
145.6 (kDa)
Ref: TM-T76812
| 1mg | 250.00 € | ||
| 5mg | 755.00 € | ||
| 10mg | 1,283.00 € | ||
| 25mg | 1,863.00 € | ||
| 50mg | 2,547.00 € | ||
| 100mg | 3,467.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Lumretuzumab
CAS:1448327-63-6
Lumretuzumab (RG-7116) is a humanized anti-HER3 monoclonal antibody with antitumor activity.
Color and Shape:
Liquid
Ref: TM-T76818
| 1mg | 264.00 € | ||
| 5mg | 660.00 € | ||
| 10mg | 1,035.00 € | ||
| 25mg | 1,568.00 € | ||
| 50mg | 2,110.00 € | ||
| 100mg | 2,783.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
GSK-3 Inhibitor 5
CAS:20099-89-2
4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.
Formula:
C9H6BrNO
Purity:
99.58%
Color and Shape:
Off-White To Light Yellow Crystalline Powder
Molecular weight:
224.05
Ref: TM-T77554
| 1g | 34.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Pertuzumab
CAS:380610-27-5
Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called …
Purity:
98.00%
Color and Shape:
Liquid
Molecular weight:
148 kDa
Ref: TM-T9909
| 1mg | 180.00 € | ||
| 5mg | 550.00 € | ||
| 10mg | 792.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
Mutated EGFR-IN-3
CAS:2375107-27-8
Mutated EGFR-IN-3: ATP-competitive, selective dibenzodiazepinone inhibitor for EGFR mutations, IC50 12-13 nM.
Formula:
C31H29FN4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
508.59
Ref: TM-T12131
| 25mg | 1,444.00 € |
Estimated delivery in United States, on Tuesday 4 Mar 2025
