PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
- AMPK(171 products)
- ATM/ATR(72 products)
- DNA-PK(48 products)
- EGFR(591 products)
- MELK(7 products)
- PDK(9 products)
- PI3K(233 products)
- S6 Kinase(8 products)
- gsk-3(110 products)
- mTOR(162 products)
Show 2 more subcategories
Found 1007 products of "PI3K/Akt/mTOR Signaling"
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EGFR-IN-67
CAS:EGFR-IN-67 (Compound 7d) is a potent inhibitor of EGFR with anticancer activity (IC 50 = 0.34 μM) [1].Formula:C18H17N3SColor and Shape:SolidMolecular weight:307.41LTURM-36
CAS:LTURM-36 is a novel inhibitor of PI 3-kinase delta.Formula:C22H18N2O3Purity:98%Color and Shape:SolidMolecular weight:358.39AP1867
CAS:AP1867 (FK506-binding protein) is a synthetic FKBP12 F36V-directed ligand coupled to THOX derivatives, facilitating targeted protein interactions and intracellular modulation studies.Formula:C38H47NO11Purity:99.86%Color and Shape:SolidMolecular weight:693.78Ref: TM-T14297
1mg145.00€5mg354.00€10mg530.00€25mg938.00€50mg1,473.00€100mg2,213.00€1mL*10mM (DMSO)540.00€DNA-PK-IN-1
CAS:DNA-PK-IN-1 is a potent inhibitor of DNA-PK. DNA-PK-IN-1 has potential for cancer disease research.Formula:C23H26N8O2Color and Shape:SolidMolecular weight:446.5ZDWX-25
CAS:ZDWX-25, a strong GSK-3β & DYRK1A inhibitor, kills SH-SY5Y/HL-7702 cells, may aid Alzheimer's research; IC50: 71 nM for GSK-3β.Formula:C17H15N3O3Color and Shape:SolidMolecular weight:309.32RG 14467
CAS:RG 14467 is an antagonist of epidermal growth factor-urogastrone.Formula:C14H14N2O3Color and Shape:SolidMolecular weight:258.27RG 14921
CAS:RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase, and cAMP-dependent kinase.Formula:C11H9NO3Color and Shape:SolidMolecular weight:203.19PI3Kα-IN-13
CAS:PI3Kα-IN-13 (Compound 18a), a PI3Kα inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis and hampers the proliferation of various cancer cell lines,Formula:C21H19N5O3Purity:98%Color and Shape:SolidMolecular weight:389.41PI3K/mTOR Inhibitor-8
CAS:PI3K/mTOR Inhibitor-8: Dual PI3Kα (IC50: 0.46 nM) & mTOR (IC50: 12 nM) inhibitor; blocks G1/S phase & induces apoptosis in HCT-116 cells.Formula:C23H22N8O4SColor and Shape:SolidMolecular weight:506.54NVP-CLR457
CAS:NVP-CLR457 is an oral pan-class I PI3K inhibitor with dose-dependent antitumor activity.Formula:C18H20F3N7O4Color and Shape:SolidMolecular weight:455.39AFN941
CAS:AFN941 is a staurosporine analog, acting as a Jak3-specific inhibitor.Formula:C28H30N4O3Color and Shape:SolidMolecular weight:470.56MIPS-9922
CAS:MIPS-9922: potent PI3Kβ inhibitor; prevents αIIbβ3 activation, platelet adhesion, and ADP-triggered aggregation.Formula:C28H31F2N9O2Purity:98%Color and Shape:SolidMolecular weight:563.6NSC81111
CAS:NSC81111 shows anticaner effects which is a potent and orally active inhibitor of EGFR-TK (IC50 = 0.15 nM) [1].Formula:C19H16O4Color and Shape:SolidMolecular weight:308.33EGFR/HER2-IN-2
CAS:EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).Formula:C26H23N5O3Color and Shape:SolidMolecular weight:453.49mTOR inhibitor-2
CAS:mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).Formula:C23H21N7OPurity:98%Color and Shape:SolidMolecular weight:411.46GNE-293
CAS:GNE-293 is a potent and selective PI3Kδ inhibitor.Formula:C28H36N8O4SPurity:98%Color and Shape:SolidMolecular weight:580.7AZD6482 (S-isomer)
CAS:AZD6482 is a potent PI3Kβ inhibitor with IC(50) of 0.01 μm, blocking insulin-stimulated glucose uptake. IC(50) for adipocytes is 4.4 μm.Formula:C22H24N4O4Color and Shape:SolidMolecular weight:408.45NC03
CAS:NC03 is a PI4K2A inhibitor that reduces intracellular PI4P pools in the Golgi apparatus and endosomes, cancer research.Formula:C21H21N3O7SPurity:99.73%Color and Shape:SolidMolecular weight:459.47Ref: TM-T71797
1mgTo inquire5mg250.00€10mgTo inquire25mg753.00€50mg1,074.00€1mL*10mM (DMSO)To inquirePI-540
CAS:PI-540 is a potent and selective inhibitor of class 1A phosphatidylinositide 3-kinases (PI3K).Formula:C22H27N5O2SColor and Shape:SolidMolecular weight:425.55DNA-PK-IN-3
CAS:DNA-PK-IN-3 is a potent DNA-PK inhibitor, enhancing radio/chemotherapy and reducing tumors with limited side effects.Formula:C19H19N9OColor and Shape:SolidMolecular weight:389.41
