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PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.

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Subcategories of "PI3K/Akt/mTOR Signaling"

AMPK

ATM/ATR

DNA-PK

EGFR

MELK

PDK

PI3K

S6 Kinase

gsk-3

mTOR

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Products of "PI3K/Akt/mTOR Signaling"

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products per page. 694 products on this category.

BrandProduct dataPurityPrice rangeEstimated delivery
Targetmol logo
YS-363
REF: TM-T80748CAS: 2470908-90-6 		98%To inquireTue 04 Feb 25
Targetmol logo
Simotinib
REF: TM-T35916CAS: 944258-89-3 		99.7%185.00 €~1,838.00 €Tue 04 Feb 25
Targetmol logo
BGB-102
REF: TM-T10531CAS: 807640-87-5 		99.02%305.00 €~2,899.00 €Tue 04 Feb 25
Targetmol logo
EDI048
REF: TM-T79876CAS: 2767264-57-1 		98%To inquireTue 04 Feb 25
Targetmol logo
DNA-PK-IN-10
REF: TM-T79165CAS: 2919315-89-0 		98%To inquireTue 04 Feb 25
Targetmol logo
BGB-8035
REF: TM-T73381CAS: 2283349-24-4 		96.74%384.00 €~3,154.00 €Tue 04 Feb 25
Targetmol logo
PI3K/mTOR Inhibitor-12
REF: TM-T72374CAS: 2891692-83-2 		98%1,000.00 €~2,617.00 €Tue 04 Feb 25
Targetmol logo
MIPS-21335
REF: TM-T81791CAS: 2569296-51-9 		98%To inquireTue 04 Feb 25
Targetmol logo
HKI-357
REF: TM-T11569CAS: 848133-17-5 		95.11%78.00 €~920.00 €Tue 04 Feb 25
Targetmol logo
Zandelisib
REF: TM-T13386CAS: 1401436-95-0 		99.15%94.00 €~2,971.00 €Tue 04 Feb 25
Targetmol logo
EGFR-IN-85
REF: TM-T78574CAS: 1956378-29-2 		98%907.00 €~2,337.00 €Tue 04 Feb 25
Targetmol logo
MTI-31
REF: TM-T35343CAS: 1567915-38-1 		99.76%183.00 €~2,023.00 €Tue 04 Feb 25
Targetmol logo
LAS191954
REF: TM-T11818CAS: 1403947-26-1 		98%1,183.00 €~3,168.00 €Tue 04 Feb 25
Targetmol logo
PI3Kδ-IN-1
REF: TM-T12462CAS: 1911564-39-0 		99.3%63.00 €~713.00 €Tue 04 Feb 25
Targetmol logo
EGFR-IN-61
REF: TM-T73128CAS: 2890261-81-9 		98%907.00 €~2,337.00 €Tue 04 Feb 25
Targetmol logo
SAR-260301
REF: TM-T16841CAS: 1260612-13-2 		98.65%44.00 €~1,326.00 €Tue 04 Feb 25
Targetmol logo
EGFR/CSC-IN-1
REF: TM-T73995CAS: 2820447-02-5 		98%To inquireTue 04 Feb 25
Targetmol logo
ALK/EGFR-IN-1
REF: TM-T79392CAS: 2730430-08-5 		98%1,000.00 €~2,617.00 €Tue 04 Feb 25
Targetmol logo
Lifirafenib
REF: TM-T22272CAS: 1446090-79-4 		98% - 98.25%To inquireTue 04 Feb 25
Targetmol logo
ZLN024
REF: TM-T13411CAS: 723249-01-2 		99.82%94.00 €~2,775.00 €Tue 04 Feb 25
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YS-363
Targetmol logo
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YS-363

CAS:2470908-90-6
YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor …
Formula:
C30H30N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
494.58

Ref: TM-T80748

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
Simotinib
Targetmol logo
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Simotinib

CAS:944258-89-3
Simotinib (AL-6802) is an EGFR tyrosine kinase inhibitor (IC50 : 19.9 nM) with antitumour activity …
Formula:
C25H26ClFN4O4
Purity:
99.7%
Color and Shape:
Liquid
Molecular weight:
500.95

Ref: TM-T35916

1mg185.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
BGB-102
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BGB-102

CAS:807640-87-5
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR …
Formula:
C22H25BrN4O2
Purity:
99.02%
Color and Shape:
Solid
Molecular weight:
457.36

Ref: TM-T10531

1mg305.00 €
5mg759.00 €
10mg1,002.00 €
25mg1,512.00 €
50mg2,032.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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discount label
EDI048
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EDI048

CAS:2767264-57-1
EDI048, also known as compound 1.16, is an orally active inhibitor of Cryptosporidium PI4K, utilized …
Formula:
C25H21ClN4O4
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
476.91

Ref: TM-T79876

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 4 Feb 2025
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DNA-PK-IN-10
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DNA-PK-IN-10

CAS:2919315-89-0
DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell …
Formula:
C25H28N6O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
444.53

Ref: TM-T79165

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 4 Feb 2025
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BGB-8035
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BGB-8035

CAS:2283349-24-4
BGB-8035 is a BTK inhibitor with antitumor activity that inhibits BTK, TEC, and EGFR.BGB-8035 is …
Formula:
C24H31N5O4
Purity:
96.74%
Color and Shape:
Solid
Molecular weight:
453.53

Ref: TM-T73381

1mg384.00 €
5mg911.00 €
10mg1,225.00 €
25mg1,828.00 €
50mg2,394.00 €
100mg3,154.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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discount label
PI3K/mTOR Inhibitor-12
Targetmol logo
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PI3K/mTOR Inhibitor-12

CAS:2891692-83-2
PI3K/mTOR Inhibitor-12: oral, potent, selective; IC50: PI3Kα 0.06 nM, mTOR 3.12 nM; strong antitumor; less …
Formula:
C27H27F2N9O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
611.62

Ref: TM-T72374

25mg1,549.00 €
50mg2,038.00 €
100mg2,617.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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MIPS-21335
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MIPS-21335

CAS:2569296-51-9
MIPS-21335 is a potent PI3KC2α inhibitor with an IC50 value of 7 nM and additionally …
Formula:
C24H21N7O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
487.47

Ref: TM-T81791

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 4 Feb 2025
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discount label
HKI-357
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HKI-357

CAS:848133-17-5
HKI-357 irreversibly inhibits EGFR/ERBB2 (IC50: 34/33 nM), blocks EGFR Y1068 autophosphorylation, and AKT/MAPK phosphorylation.
Formula:
C31H29ClFN5O3
Purity:
95.11%
Color and Shape:
Solid
Molecular weight:
574.05

Ref: TM-T11569

1mg78.00 €
5mg149.00 €
10mg222.00 €
25mg452.00 €
50mg647.00 €
100mg920.00 €
1mL*10mM (DMSO)186.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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discount label
Zandelisib
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Zandelisib

CAS:1401436-95-0
Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic …
Formula:
C31H38F2N8O
Purity:
99.15%
Color and Shape:
Solid
Molecular weight:
576.68

Ref: TM-T13386

1mg94.00 €
5mg174.00 €
10mg290.00 €
25mg470.00 €
50mg634.00 €
100mg872.00 €
200mg1,171.00 €
1mL*10mM (DMSO)217.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
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discount label
EGFR-IN-85
Targetmol logo
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EGFR-IN-85

CAS:1956378-29-2
EGFR-IN-85 (Compound 1), an EGFR inhibitor, exhibits potent activity with an IC50 of 0.19 μM …
Formula:
C26H30N8O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
486.57

Ref: TM-T78574

25mg1,410.00 €
50mg1,851.00 €
100mg2,337.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
MTI-31
Targetmol logo
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MTI-31

CAS:1567915-38-1
MTI-31 (LXI-15029) is a potent oral mTORC1/2 inhibitor with a Kd of 0.20 nM, >5,000-fold …
Formula:
C26H30N6O3
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
474.55

Ref: TM-T35343

1mg183.00 €
5mg423.00 €
10mg645.00 €
25mg1,012.00 €
50mg1,447.00 €
100mg2,023.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
LAS191954
Targetmol logo
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LAS191954

CAS:1403947-26-1
LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : …
Formula:
C20H15N9O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
397.39

Ref: TM-T11818

25mg1,827.00 €
50mg2,404.00 €
100mg3,168.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
PI3Kδ-IN-1
Targetmol logo
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PI3Kδ-IN-1

CAS:1911564-39-0
PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM).
Formula:
C22H20F3N7O2
Purity:
99.3%
Color and Shape:
Solid
Molecular weight:
471.44

Ref: TM-T12462

1mg63.00 €
5mg143.00 €
10mg221.00 €
25mg369.00 €
50mg527.00 €
100mg713.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
EGFR-IN-61
Targetmol logo
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EGFR-IN-61

CAS:2890261-81-9
EGFR-IN-61 inhibits EGFR kinase (IC50: 42 nM L858R/T790M, 137 nM L858R/T790M/C797S, 743 nM WT) and …
Formula:
C33H37ClN8O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
629.15

Ref: TM-T73128

25mg1,410.00 €
50mg1,851.00 €
100mg2,337.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
SAR-260301
Targetmol logo
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SAR-260301

CAS:1260612-13-2
SAR-260301 is an orally available and selective inhibitor of PI3Kβ (IC50: 23 nM).
Formula:
C19H22N4O3
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
354.4

Ref: TM-T16841

2mg44.00 €
5mg67.00 €
10mg89.00 €
25mg177.00 €
50mg269.00 €
100mg378.00 €
200mg533.00 €
1mL*10mM (DMSO)72.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
No image
Targetmol logo
+ info

EGFR/CSC-IN-1

CAS:2820447-02-5
EGFR/CSC-IN-1 is a dual inhibitor targeting both the epidermal growth factor receptor (EGFR [IC50 10.52 …
Formula:
C54H54Cl2FN7O7S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1067.08

Ref: TM-T73995

5mgTo inquire
50mgTo inquire
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
ALK/EGFR-IN-1
Targetmol logo
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ALK/EGFR-IN-1

CAS:2730430-08-5
ALK/EGFR-IN-1 (Compound 8l) is a dual inhibitor targeting both ALK and EGFR, effectively blocking their …
Formula:
C27H34ClN7O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
572.12

Ref: TM-T79392

25mg1,549.00 €
50mg2,038.00 €
100mg2,617.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
Lifirafenib
Targetmol logo
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Lifirafenib

CAS:1446090-79-4
Lifirafenib (Beigene-283) is a potent inhibitor of RAF family kinases and EGFR in biochemical assays …
Formula:
C25H17F3N4O3
Purity:
98% - 98.25%
Color and Shape:
Solid
Molecular weight:
478.42

Ref: TM-T22272

1mg35.00 €
5mg68.00 €
10mg95.00 €
25mg185.00 €
50mgTo inquire
100mgTo inquire
1mL*10mM (DMSO)89.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
discount label
ZLN024
Targetmol logo
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ZLN024

CAS:723249-01-2
ZLN024 is an activator of AMPK allosteric.
Formula:
C13H13BrN2OS
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
325.22

Ref: TM-T13411

1mg94.00 €
5mg181.00 €
10mg273.00 €
25mg436.00 €
50mg621.00 €
100mg835.00 €
200mg1,089.00 €
1mL*10mM (DMSO)182.00 €
Estimated delivery in United States, on Tuesday 4 Feb 2025
+ info
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