PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
Antitumor agent-116
Antitumor Agent-116 (Compound 6C) is an anti-tumor agent that exhibits anti-proliferative properties and induces apoptosis.
Formula:
C31H23BrN4O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
627.51
Ref: TM-T79582
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Pimurutamab
CAS:2251771-76-1
Pimurutamab, a humanized IgG1-κ antibody, selectively targets the epidermal growth factor receptor (EGFR) and is …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80612
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Pertuzumab
CAS:380610-27-5
Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called …
Purity:
98.00%
Color and Shape:
Liquid
Molecular weight:
148 kDa
Ref: TM-T9909
| 1mg | 177.00 € | ||
| 5mg | 537.00 € | ||
| 10mg | 773.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Becotatug
CAS:2648260-93-7
Becotatug (JMT-101) is an IgG1 antibody that targets EGFR and can be conjugated to Afatinib …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80574
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR/HER2/DHFR-IN-3
EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values …
Purity:
98%
Ref: TM-T82492
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Thioether-cyclized helix B peptide, CHBP
CAS:1453840-35-1
Thioether-cyclized helix B peptide (CHBP) enhances metabolic stability and exerts renoprotective effects by promoting autophagy …
Formula:
C56H93N19O22S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1416.52
Ref: TM-T80546
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
PI3K-IN-46
CAS:304645-61-2
PI3K-IN-46 is a specific inhibitor of PI3Kγ.
Formula:
C13H9N3OS
Purity:
97.51%
Color and Shape:
Soild
Molecular weight:
255.3
Ref: TM-T64392
| 1mg | 112.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 365.00 € | ||
| 25mg | 547.00 € | ||
| 50mg | 770.00 € | ||
| 100mg | 1,035.00 € | ||
| 200mg | 1,404.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Inetetamab
Inetetamab, a monoclonal antibody, targets domain IV of the HER2 receptor and demonstrates antitumor activities …
Purity:
98%
Ref: TM-T78335
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
MeBIO
CAS:667463-95-8
MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM …
Formula:
C17H12BrN3O2
Purity:
98.84%
Color and Shape:
Solid
Molecular weight:
370.2
Ref: TM-T21966
| 1mg | 39.00 € | ||
| 5mg | 74.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 510.00 € | ||
| 500mg | 1,105.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
PH14
PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for …
Purity:
98%
Ref: TM-T81499
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Mutated EGFR-IN-3
CAS:2375107-27-8
Mutated EGFR-IN-3: ATP-competitive, selective dibenzodiazepinone inhibitor for EGFR mutations, IC50 12-13 nM.
Formula:
C31H29FN4O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
508.59
Ref: TM-T12131
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
SN32976
CAS:1246202-11-8
SN32976 is a pan PI3K inhibitor. SN32976 potently inhibited PI3K isoforms and mTOR, displaying preferential …
Formula:
C24H33F2N9O4S
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
581.64
Ref: TM-T9788
| 1mg | 111.00 € | ||
| 5mg | 241.00 € | ||
| 10mg | 356.00 € | ||
| 25mg | 543.00 € | ||
| 50mg | 760.00 € | ||
| 100mg | 1,018.00 € | ||
| 200mg | 1,358.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Depatuxizumab
CAS:1471999-69-5
Depatuxizumab, a brain-penetrant, humanized anti-EGFR monoclonal antibody, selectively inhibits the growth of mutant EGFRvIII and …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T78326
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR-IN-83
EGFR-IN-83 (Compound 9), an EGFR inhibitor with an IC50 of 2.53 nM, exhibits antiproliferative effects …
Formula:
C22H17F3N4O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
410.39
Ref: TM-T79651
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
CH7233163
CH7233163 is a useful organic compound for research related to life sciences and the catalog …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T35334
| 5mg | 317.00 € | ||
| 25mg | 937.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
JH-XI-10-02
CAS:2209085-22-1
JH-XI-10-02 selectively degrades CDK8 (IC50: 159 nM) through proteasome, sparing CDK8 mRNA and CDK19.
Formula:
C53H69N5O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
920.161
Ref: TM-T13743
| 2mg | 1,366.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
STX-478
CAS:2883540-92-7
STX-478 (compound 80), an orally administered, CNS-penetrant allosteric mutant-selective PI3Kα inhibitor, demonstrates significant and sustained …
Formula:
C16H12F5N5O2
Purity:
99.59%
Color and Shape:
Liquid
Molecular weight:
401.29
Ref: TM-T78211
| 1mg | 315.00 € | ||
| 5mg | 801.00 € | ||
| 10mg | 1,279.00 € | ||
| 25mg | 2,582.00 € | ||
| 50mg | 4,129.00 € | ||
| 1mL*10mM (DMSO) | 713.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR/HER2/DHFR-IN-2
EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values …
Purity:
98%
Ref: TM-T82493
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
hSMG-1 inhibitor 11j
CAS:1402452-15-6
hSMG-1 inhibitor 11j: pyrimidine, IC50=0.11 nM, >455x selective vs. mTOR/PI3Kα/γ/CDK1/CDK2; cancer research use.
Formula:
C27H28ClN7O3S
Purity:
99.04% - 99.29%
Color and Shape:
Solid
Molecular weight:
566.07
Ref: TM-T8884
| 1mg | 158.00 € | ||
| 2mg | 227.00 € | ||
| 5mg | 385.00 € | ||
| 10mg | 574.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,243.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Wnt/β-catenin agonist 2
CAS:943820-93-7
Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist.
Formula:
C13H12N4O3
Purity:
99.58%
Color and Shape:
Liquid
Molecular weight:
272.26
Ref: TM-T41094
| 1mg | 53.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 311.00 € | ||
| 50mg | 439.00 € | ||
| 100mg | 624.00 € | ||
| 500mg | 1,235.00 € | ||
| 1mL*10mM (DMSO) | 111.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
