PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
MELK-8a Dihydrochloride
MELK-8a Dihydrochloride is a useful organic compound for research related to life sciences and the …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T35342
| 5mg | 473.00 € | ||
| 25mg | 1,432.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR mutant-IN-1
EGFR mutant-in-1, a 5-methylpyrimidopyridone, selectively inhibits EGFRL858R/T790M/C797S mutants with an IC50 of 27.5 nM, lessening …
Formula:
C34H39ClFN7O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
632.17
Ref: TM-T11164
| 100mg | To inquire | ||
| 500mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
JAK 3 inhibitor IV
CAS:58753-54-1
JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, …
Formula:
C16H19NO
Purity:
98%
Color and Shape:
Solid
Molecular weight:
241.33
Ref: TM-T2460
| 5mg | 68.00 € | ||
| 10mg | 107.00 € | ||
| 25mg | 190.00 € | ||
| 50mg | 315.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Chamigrenal
CAS:19912-84-6
β-Chamigrenal: Anti-inflammatory, inhibits NO and PGE2 in macrophages, PAF antagonist (IC50=1.2x10^-4 M), weakly cytotoxic to …
Formula:
C15H22O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
218.33
Ref: TM-T3P2855
| 1mg | 88.00 € | ||
| 5mg | 350.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK-3β inhibitor 14
CAS:863004-48-2
GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.
Formula:
C17H17NOS
Purity:
99.88%
Color and Shape:
Liquid
Molecular weight:
283.39
Ref: TM-T67856
| 1mg | 94.00 € | ||
| 5mg | 193.00 € | ||
| 10mg | 294.00 € | ||
| 25mg | 469.00 € | ||
| 50mg | 628.00 € | ||
| 100mg | 850.00 € | ||
| 200mg | 1,130.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Befotertinib
CAS:1835667-63-4
Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies …
Formula:
C29H32F3N7O2
Purity:
99.40%
Color and Shape:
Liquid
Molecular weight:
567.61
Ref: TM-T39275
| 1mg | 87.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 513.00 € | ||
| 50mg | 730.00 € | ||
| 100mg | 1,002.00 € | ||
| 1mL*10mM (DMSO) | 230.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK3β inhibitor II
CAS:478482-75-6
GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of …
Formula:
C14H10IN3OS
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
395.22
Ref: TM-T21956
| 5mg | 51.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 255.00 € | ||
| 100mg | 346.00 € | ||
| 500mg | To inquire | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
![6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile](https://static.cymitquimica.com/products/TM/thumb/T77685.jpg)
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile
CAS:1207836-10-9
6-Bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile is a PDK1 inhibitor with anticancer and antiproliferative activity that can be used to …
Formula:
C9H6BrN3O
Purity:
98.81%
Color and Shape:
Solid
Molecular weight:
252.07
Ref: TM-T77685
| 100mg | 34.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Astragaloside VI
CAS:84687-45-6
Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.
Formula:
C47H78O19
Purity:
98%
Color and Shape:
Solid
Molecular weight:
947.122
Ref: TM-T13559
| 10mg | 562.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
IC 86621
CAS:404009-40-1
IC 86621: DNA-PK ATP-competitive inhibitor, IC50 120 nM, enhances DSB antitumor effects, EC50 68 µM …
Formula:
C12H15NO3
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
221.25
Ref: TM-T9760
| 5mg | 37.00 € | ||
| 10mg | 49.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 107.00 € | ||
| 100mg | 157.00 € | ||
| 1mL*10mM (DMSO) | 39.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
MTX-241F
MTX-241F, a selective small molecule inhibitor, targets members of the EGFR and PI3 kinase families.
Formula:
C20H14ClFN6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
392.82
Ref: TM-T78877
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
ARUK2001607
ARUK2001607 selectively inhibits PI5P4Kγ (Kd=7.1 nM) with high selectivity over 150+ kinases.
Formula:
C14H13N3O2S2
Purity:
99.86%
Color and Shape:
Soild
Molecular weight:
319.40
Ref: TM-T67845
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 110.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Barecetamab
CAS:2275727-74-5
Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.
Color and Shape:
Liquid
Ref: TM-T76918
| 1mg | 307.00 € | ||
| 5mg | 990.00 € | ||
| 10mg | 1,335.00 € | ||
| 25mg | 1,979.00 € | ||
| 50mg | 2,669.00 € | ||
| 100mg | 3,602.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
mTORC1-IN-1
mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and …
Purity:
98%
Ref: TM-T81743
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Safingol hydrochloride
CAS:139755-79-6
Safingol hydrochloride (L-threo-dihydrosphingosine hydrochloride) is a PKC-specific inhibitor that inhibits PKC and PI3k and induces …
Formula:
C18H40ClNO2
Purity:
99.31% - 99.71%
Color and Shape:
Soild
Molecular weight:
337.969
Ref: TM-T83978
| 1mg | 184.00 € | ||
| 5mg | 455.00 € | ||
| 10mg | 651.00 € | ||
| 25mg | 1,016.00 € | ||
| 50mg | 1,401.00 € | ||
| 100mg | 1,834.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Intetumumab
CAS:725735-28-4
Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for …
Color and Shape:
Liquid
Molecular weight:
145.6 (kDa)
Ref: TM-T76812
| 1mg | 246.00 € | ||
| 5mg | 742.00 € | ||
| 10mg | 1,260.00 € | ||
| 25mg | 1,829.00 € | ||
| 50mg | 2,501.00 € | ||
| 100mg | 3,406.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
AZ7550 hydrochloride
CAS:2309762-40-9
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R …
Formula:
C27H32ClN7O2
Purity:
97.07%
Color and Shape:
Solid
Molecular weight:
522.04
Ref: TM-T13564L
| 1mg | 122.00 € | ||
| 5mg | 240.00 € | ||
| 10mg | 371.00 € | ||
| 25mg | 619.00 € | ||
| 50mg | 882.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Serclutamab
CAS:2140172-41-2
Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80614
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Lumretuzumab
CAS:1448327-63-6
Lumretuzumab (RG-7116) is a humanized anti-HER3 monoclonal antibody with antitumor activity.
Color and Shape:
Liquid
Ref: TM-T76818
| 1mg | 259.00 € | ||
| 5mg | 649.00 € | ||
| 10mg | 1,018.00 € | ||
| 25mg | 1,540.00 € | ||
| 50mg | 2,072.00 € | ||
| 100mg | 2,735.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ZLN 024 hydrochloride
CAS:1883548-91-1
ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations …
Formula:
C13H14BrClN2OS
Purity:
99.86%
Color and Shape:
Odour Solid
Molecular weight:
361.68
Ref: TM-T41162
| 5mg | 47.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 146.00 € | ||
| 50mg | 253.00 € | ||
| 100mg | 368.00 € | ||
| 500mg | 846.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
