PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
Rociletinib
CAS:1374640-70-6
Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor …
Formula:
C27H28F3N7O3
Purity:
98.39% - 99.25%
Color and Shape:
Solid
Molecular weight:
555.55
Ref: TM-T2369
| 5mg | 49.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 96.00 € | ||
| 50mg | 121.00 € | ||
| 100mg | 194.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
WAY-270360
CAS:476633-98-4
WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.
Formula:
C22H19N3O3
Purity:
98.66%
Color and Shape:
Liquid
Molecular weight:
373.4
Ref: TM-T60064
| 1mg | 63.00 € | ||
| 5mg | 137.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 324.00 € | ||
| 50mg | 455.00 € | ||
| 100mg | 641.00 € | ||
| 500mg | 1,272.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ARRY-380 (analog )
CAS:937265-83-3
ARRY-380 analog (HER2-Inhibitor-1) is a potent and selective HER2 inhibitor.
Formula:
C29H27N7O4S
Purity:
98.22%
Color and Shape:
Solid
Molecular weight:
569.63
Ref: TM-T2518
| 1mg | 35.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 108.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 261.00 € | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Cinrebafusp alfa
CAS:2218515-90-1
Cinrebafusp alfa (PRS 343) is an anticalin-based bispecific drug with high affinity for both CD137/HER2, …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80590
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK3-IN-4
CAS:748145-19-9
GSK3-IN-4 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in …
Formula:
C18H20N4O
Purity:
97.1%
Color and Shape:
Soild
Molecular weight:
308.38
Ref: TM-T64366
| 1mg | 113.00 € | ||
| 5mg | 249.00 € | ||
| 10mg | 366.00 € | ||
| 25mg | 550.00 € | ||
| 50mg | 769.00 € | ||
| 100mg | 1,049.00 € | ||
| 500mg | 2,098.00 € | ||
| 1mL*10mM (DMSO) | 244.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
PITCOIN4
PITCOIN4 is a Class II Alpha PI3K-C2α inhibitor with high selectivity, demonstrating nanomolar inhibition of …
Purity:
98%
Ref: TM-T81453
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
MRT 67307 dihydrochloride
CAS:1781882-89-0
MRT 67307 dihydrochloride inhibits IKKε/TBK-1, ULK1/2, and blocks autophagy, with IC50s of 160/19, 45/38 nM …
Formula:
C26H38Cl2N6O2
Purity:
98.43%
Color and Shape:
Soild
Molecular weight:
537.53
Ref: TM-T36994
| 5mg | 56.00 € | ||
| 10mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK3a-IN-38
CAS:1062138-03-7
GSK3a-IN-38 is a novel small molecule compound that has inhibitory effects on GSK-3a.
Formula:
C18H20N4O
Purity:
99.75%
Color and Shape:
Soild
Molecular weight:
308.38
Ref: TM-T77671
| 1mg | 181.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 647.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,384.00 € | ||
| 100mg | 1,830.00 € | ||
| 500mg | 3,664.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Tyrosine kinase-IN-7
CAS:345615-74-9
Tyrosine kinase-IN-7 is a potent inhibitor of the tyrosine kinase EGFR, inhibiting EGFR(WT) and EGFR(T790M) …
Formula:
C16H15N3OS
Purity:
99.93%
Color and Shape:
Liquid
Molecular weight:
297.38
Ref: TM-T77746
| 5mg | 35.00 € | ||
| 10mg | 47.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
AMPK activator 2 hydrochloride( 2410961-69-0 Free base)
AMPK activator 2 hydrochloride upregulates the AMPK signaling pathway and inhibits the proliferation and migration …
Formula:
C13H19ClF3N5
Purity:
98%
Color and Shape:
Soild
Molecular weight:
337.77
Ref: TM-T60675L
| 1mg | 86.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 296.00 € | ||
| 25mg | 497.00 € | ||
| 50mg | 709.00 € | ||
| 100mg | 917.00 € | ||
| 500mg | 1,839.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
740 Y-P acetate
740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends …
Formula:
C143H226N43O41PS3
Purity:
98%
Color and Shape:
Soild
Molecular weight:
3330.79
Ref: TM-TQ0003L1
| 1mg | 92.00 € | ||
| 5mg | 263.00 € | ||
| 10mg | 408.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Insecticidal agent 364
CAS:556055-08-4
Insecticidal agent 364 is a selective small molecule inhibitor of rapamycin kinase target protein.
Formula:
C23H18N4O3S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
430.48
Ref: TM-T67914
| 5mg | 46.00 € | ||
| 10mg | 68.00 € | ||
| 25mg | 122.00 € | ||
| 50mg | 177.00 € | ||
| 100mg | 262.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
PI5P4Ks-IN-2
CAS:2766854-03-7
PI5P4Ks-IN-2 inhibits PI5P4K isoforms α, β, γ, γ+ with IC50 <4.3, <4.6, 6.2, 0.32 µM, …
Formula:
C22H23N5
Purity:
99.09% - 99.21%
Color and Shape:
Soild
Molecular weight:
357.45
Ref: TM-T72032
| 1mg | 157.00 € | ||
| 5mg | 330.00 € | ||
| 10mg | 491.00 € | ||
| 25mg | 829.00 € | ||
| 50mg | 1,086.00 € | ||
| 100mg | 1,420.00 € | ||
| 1mL*10mM (DMSO) | 361.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Anticancer agent 137
Anticancer agent 137 (8q), a potent PI3k inhibitor, exhibits broad-spectrum anticancer activity by inducing G2/M …
Formula:
C26H27NO6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
449.5
Ref: TM-T79482
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR/PI3Kα-IN-1
EGFR/PI3Kα-IN-1 (compound 30k), a dual EGFR/PI3Kα inhibitor, exhibits potent activity with IC 50 values of …
Formula:
C50H49N11O5S
Color and Shape:
Liquid
Molecular weight:
916.06
Ref: TM-T200282
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
PI3Kδ-IN-18
Se15, a selective PI3Kδ inhibitor, exhibits potency with an IC50 value of less than 0.1nM …
Purity:
98%
Ref: TM-T81467
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK-3β inhibitor 19
GSK-3β Inhibitor 19 (compound 36) is an inhibitor of GSK-3β with an IC50 value of …
Formula:
C15H12N4O2S
Color and Shape:
Liquid
Molecular weight:
312.35
Ref: TM-T200354
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
IHMT-PI3Kδ-372 S-isomer
CAS:2429889-61-0
IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM.
Formula:
C26H23F2N7O2
Purity:
99.68%
Color and Shape:
Soild
Molecular weight:
503.5
Ref: TM-T60196
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 552.00 € | ||
| 50mg | 772.00 € | ||
| 100mg | 1,053.00 € | ||
| 1mL*10mM (DMSO) | 309.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Multi-target kinase inhibitor 2
Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, …
Purity:
98%
Ref: TM-T81739
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Herceptide
CAS:3027722-28-4
Herceptide (HER2-targeting peptide), a peptide that targets HER2, can be conjugated with the near-infrared fluorescent …
Formula:
C76H110N22O23
Color and Shape:
Liquid
Molecular weight:
1699.82
Ref: TM-TP2876
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
