PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
GSK2292767 FA
GSK2292767 FA: potent PI3Kδ inhibitor, pIC50=10.1, 500x selectivity, for respiratory research.
Formula:
C25H30N6O7S
Purity:
99.21%
Color and Shape:
Soild
Molecular weight:
558.61
Ref: TM-T6850L
| 1mg | 151.00 € | ||
| 5mg | 362.00 € | ||
| 10mg | 543.00 € | ||
| 25mg | 872.00 € | ||
| 50mg | 1,184.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Umbralisib R-enantiomer
CAS:1532533-69-9
Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer …
Formula:
C31H24F3N5O3
Purity:
95.61%
Color and Shape:
Solid
Molecular weight:
571.55
Ref: TM-T13140
| 1mg | 184.00 € | ||
| 5mg | 446.00 € | ||
| 10mg | 641.00 € | ||
| 25mg | 1,144.00 € | ||
| 50mg | 1,479.00 € | ||
| 100mg | 1,841.00 € | ||
| 1mL*10mM (DMSO) | 557.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
BMS-599626
CAS:714971-09-2
BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 …
Formula:
C27H27FN8O3
Purity:
98.73%
Color and Shape:
Solid
Molecular weight:
530.55
Ref: TM-T2610
| 10mg | 530.00 € | ||
| 25mg | 1,205.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK3-IN-1
CAS:478482-74-5
GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.
Formula:
C14H10ClN3OS
Purity:
99.66%
Color and Shape:
Liquid
Molecular weight:
303.77
Ref: TM-T9987
| 2mg | 43.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 102.00 € | ||
| 25mg | 218.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 464.00 € | ||
| 200mg | 629.00 € | ||
| 1mL*10mM (DMSO) | 74.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR/BRAFV600E-IN-2
E07 Aptamer, targeting the human epidermal growth factor receptor (hEGFR), competes with epidermal growth factor …
Formula:
C25H18N4O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
406.44
Ref: TM-T78849
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR-IN-84
EGFR-IN-84 (Compound 6g), an EGFR inhibitor with an IC50 of 24 nM, impedes the growth …
Formula:
C25H20N6O3S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
516.59
Ref: TM-T79386
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
MARK4 inhibitor 2
MARK4 Inhibitor 2 is a potent inhibitor of Microtubule Affinity-Regulating Kinase 4 (MARK4), exhibiting a …
Formula:
C34H30N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
542.63
Ref: TM-T79232
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR/CDK2-IN-2
EGFR/CDK2-IN-2 (compound 6a) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 …
Formula:
C49H32N12O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
884.99
Ref: TM-T79727
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
PROTAC EGFR degrader 8
CAS:2925923-46-0
PROTAC EGFR degrader 8 (T-184) is a PROTAC that selectively degrades the epidermal growth factor …
Formula:
C40H46ClN11O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
796.32
Ref: TM-T79152
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
hAChE-IN-5
hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), …
Purity:
98%
Ref: TM-T82243
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Os30
Os30 is a potent fourth-generation EGFR inhibitor, specifically targeting the EGFRC797S-TK mutation with IC50 values …
Purity:
98%
Ref: TM-T81596
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
SJF 1521
CAS:2230821-40-4
SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR …
Formula:
C57H61ClFN7O9S
Purity:
99.20%
Color and Shape:
Liquid
Molecular weight:
1074.65
Ref: TM-T36244
| 1mg | 571.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Naluzotan hydrochloride
CAS:740873-82-9
Naluzotan hydrochloride, a hERG K+ blocker (IC50: 3800 nM) and potent 5-HT1A agonist (IC50: ~20 …
Formula:
C23H39ClN4O3S
Purity:
98.61%
Color and Shape:
Liquid
Molecular weight:
487.1
Ref: TM-T68113
| 1mg | 215.00 € | ||
| 5mg | 530.00 € | ||
| 10mg | 759.00 € | ||
| 25mg | 1,168.00 € | ||
| 50mg | 1,559.00 € | ||
| 100mg | 2,116.00 € | ||
| 500mg | 4,241.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Panitumumab
CAS:339177-26-3
Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).
Purity:
99%
Color and Shape:
Solid
Molecular weight:
147 kDa
Ref: TM-T9927
| 1mg | 172.00 € | ||
| 5mg | 500.00 € | ||
| 10mg | 718.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Duvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor.
Formula:
C22H18Cl2N6O
Purity:
99.76% - 99.87%
Color and Shape:
Soild
Molecular weight:
453.32
Ref: TM-T11129L
| 1mg | 306.00 € | ||
| 5mg | 744.00 € | ||
| 10mg | 1,019.00 € | ||
| 25mg | 1,542.00 € | ||
| 50mg | 2,070.00 € | ||
| 100mg | 2,732.00 € | ||
| 1mL*10mM (DMSO) | 936.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
ElteN378
CAS:1421366-99-5
ElteN378: potently inhibits FKBP12 (Ki=0.5 nM), low weight, similar affinity to Rapamycin.
Formula:
C23H26N2O3
Purity:
98.09%
Color and Shape:
Solid
Molecular weight:
378.46
Ref: TM-T9950
| 1mg | 183.00 € | ||
| 5mg | 410.00 € | ||
| 10mg | 606.00 € | ||
| 25mg | 926.00 € | ||
| 50mg | 1,295.00 € | ||
| 100mg | 1,745.00 € | ||
| 500mg | 3,454.00 € | ||
| 1mL*10mM (DMSO) | 444.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Nezutatug
CAS:2673271-78-6
Nezutatug, an anti-HER3 antibody, serves as a research tool in cancer studies [1].
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T81679
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
BLU-945
CAS:2660250-10-0
BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine …
Formula:
C28H37FN6O3S
Purity:
99.16%
Color and Shape:
Liquid
Molecular weight:
556.7
Ref: TM-T9754
| 1mg | 94.00 € | ||
| 5mg | 200.00 € | ||
| 10mg | 299.00 € | ||
| 25mg | 510.00 € | ||
| 50mg | 762.00 € | ||
| 100mg | 1,170.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK-3 Inhibitor 5
CAS:20099-89-2
4-Cyanophenacyl bromide, a ketone, used in drug-making and organic synthesis, blocks GSK-3.
Formula:
C9H6BrNO
Purity:
99.58%
Color and Shape:
Off-White To Light Yellow Crystalline Powder
Molecular weight:
224.05
Ref: TM-T77554
| 1g | 34.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Oritinib
CAS:2035089-28-0
Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 …
Formula:
C31H37N7O2
Purity:
98.4%
Color and Shape:
Soild
Molecular weight:
539.67
Ref: TM-T60076
| 1mg | 131.00 € | ||
| 5mg | 314.00 € | ||
| 10mg | 458.00 € | ||
| 25mg | 759.00 € | ||
| 50mg | 1,012.00 € | ||
| 100mg | 1,383.00 € | ||
| 1mL*10mM (DMSO) | 365.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
