PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
mTOR inhibitor-12
mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is …
Formula:
C19H24N6O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
400.5
Ref: TM-T79212
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
PI3Kδ-IN-14
PI3Kδ-IN-14 (Compound (S)-29), a selective PI3Kδ inhibitor with an IC50 of 0.8 nM and a …
Formula:
C26H20ClFN8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
514.94
Ref: TM-T79658
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
1,5-Dihydroxyxanthone
CAS:14686-65-8
1,5-Dihydroxyxanthone inhibits EGFR-tyrosine kinase (IC50: 90.34 nM) and may block AChE/BChE.
Formula:
C13H8O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
228.203
Ref: TM-TN2504
| 5mg | 1,707.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
IHMT-PI3K-315
IHMT-PI3K-315 (20e) serves as a potent, selective inhibitor of PI3Kγ/δ, exhibiting IC 50 values of …
Formula:
C22H20F2N6O4
Color and Shape:
Liquid
Molecular weight:
470.43
Ref: TM-T200165
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
PI3K-IN-47
PI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, exhibiting …
Formula:
C50H46F4N8O8S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1027.07
Ref: TM-T78853
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
740 Y-P(TFA)(1236188-16-1 free base)
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.
Formula:
C143H223F3N43O41PS3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
3384.73
Ref: TM-TQ0003L
| 1mg | 94.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 349.00 € | ||
| 25mg | 586.00 € | ||
| 50mg | 891.00 € | ||
| 100mg | 1,336.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK-3 inhibitor 4
CAS:2227279-83-4
Orally active GSK-3 inhibitor 4 targets GSK-3α/β, CDK2/5 (IC50: 0.45-0.68 μM) and may aid in …
Formula:
C22H15F2N5O
Purity:
98.77%
Color and Shape:
Soild
Molecular weight:
403.38
Ref: TM-T77341
| 1mg | 326.00 € | ||
| 5mg | 901.00 € | ||
| 10mg | 1,115.00 € | ||
| 25mg | 1,477.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,320.00 € | ||
| 500mg | 3,648.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
(3S)-GSK-F1
CAS:1384097-27-1
(3S)-GSK-F1 is a selective small molecule inhibitor of Type III Phosphatidylinositol 4-Kinase Alpha (PI4KIIIα), pIC50=8.3.
Formula:
C27H18F5N5O4S
Purity:
99.35%
Color and Shape:
Soild
Molecular weight:
603.52
Ref: TM-T67837
| 1mg | 108.00 € | ||
| 5mg | 221.00 € | ||
| 10mg | 361.00 € | ||
| 25mg | 641.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,439.00 € | ||
| 1mL*10mM (DMSO) | 317.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK251
CAS:2125968-05-8
GSK251 is a novel, orally bioavailable inhibitor of PI3Kδ, exhibiting high potency and selectivity, with …
Formula:
C29H37FN6O4S
Purity:
98.9%
Color and Shape:
Solid
Molecular weight:
584.71
Ref: TM-T39573
| 1mg | 160.00 € | ||
| 5mg | 388.00 € | ||
| 10mg | 551.00 € | ||
| 25mg | 821.00 € | ||
| 50mg | 1,098.00 € | ||
| 100mg | 1,489.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Matuzumab
CAS:339186-68-4
Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR that can be used to …
Purity:
95%
Color and Shape:
Liquid
Molecular weight:
145.9 kDa
Ref: TM-T9922
| 1mg | 212.00 € | ||
| 5mg | 541.00 € | ||
| 10mg | 760.00 € | ||
| 25mg | 1,160.00 € | ||
| 50mg | 1,568.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
BI-4732
CAS:2769715-68-4
BI-4732 is an EGFR inhibitor with antitumor activity, inhibits EGFR activation, and suppresses T790M mutations.
Formula:
C32H36N10O2
Color and Shape:
Liquid
Molecular weight:
592.69
Ref: TM-T85354
| 1mg | 349.00 € | ||
| 5mg | 776.00 € | ||
| 10mg | 1,041.00 € | ||
| 25mg | 1,547.00 € | ||
| 50mg | 2,091.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Ligustroside
CAS:35897-92-8
Ligustroside mildly inhibits PGE2, has slight antioxidant and anti-inflammatory effects, and is moderately antiviral against …
Formula:
C25H32O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
524.51
Ref: TM-TN1871
| 5mg | 1,603.00 € | ||
| 1mL*10mM (DMSO) | 1,915.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR/CDK2-IN-3
EGFR/CDK2-IN-3 (compound 4b) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 …
Formula:
C30H20N6OS
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
512.58
Ref: TM-T79728
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Disitamab vedotin
CAS:2136633-23-1
Disitamab vedotin (RC-48) is a HER2-targeting ADC with MMAE, effective in HER2-expressing gastric cancer.
Purity:
95.00% - 98%
Color and Shape:
Liquid
Molecular weight:
Approximately 144.15 kDa
Ref: TM-T39595
| 1mg | 324.00 € | ||
| 5mg | 783.00 € | ||
| 10mg | 1,083.00 € | ||
| 25mg | 1,606.00 € | ||
| 50mg | 2,166.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Thioether-cyclized helix B peptide, CHBP TFA
Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP.
Formula:
C56H93N19O22S·xC2HF3O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1416.52 (free base)
Ref: TM-T80547
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR-IN-90
EGFR-IN-90 (compound 34), an orally active EGFR inhibitor, demonstrates potent activity against EGFRL858R/T790M/C797S with an …
Purity:
98%
Ref: TM-T82491
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
PI3K-IN-41
PI3K-IN-41 (compound 2), a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties, demonstrates potent PI3K …
Formula:
C45H39F2N5O12S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
911.88
Ref: TM-T79566
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
EGFR-IN-86
EGFR-IN-86 (compound 4i), an EGFR inhibitor (IC50: 1.5 nM), demonstrates potent activity against glioblastoma by …
Formula:
C20H21N7O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
423.49
Ref: TM-T78862
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
Neolinine
CAS:112515-37-4
Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity.
Formula:
C23H37NO6
Purity:
98%
Color and Shape:
Solid
Molecular weight:
423.55
Ref: TM-TN4638
| 5mg | 623.00 € | ||
| 1mL*10mM (DMSO) | 633.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
Duligotuzumab
CAS:1314238-96-4
Duligotuzumab (MEHD-7945A; RG 7597) is a humanized IgG-κ monoclonal antibody targeting Her3 (ErbB3) [1].
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80604
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
