PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
PS10
CAS:1564265-82-2
PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of …
Formula:
C14H13NO6S
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
323.32
Ref: TM-T12566
| 1mg | 40.00 € | ||
| 2mg | To inquire |
Estimated delivery in United States, on Monday 28 Apr 2025
Mutated EGFR-IN-1
CAS:1421372-66-8
Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, …
Formula:
C25H31N7O
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
445.56
Ref: TM-T16162
| 25mg | 58.00 € | ||
| 50mg | 66.00 € | ||
| 100mg | 89.00 € | ||
| 200mg | 116.00 € | ||
| 500mg | 187.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Erlotinib
CAS:183321-74-6
Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment …
Formula:
C22H23N3O4
Purity:
98.19% - 99.98%
Color and Shape:
White To Off-White Powder
Molecular weight:
393.44
Ref: TM-T0373
| 50mg | 48.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 79.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
P110δ-IN-1
CAS:1595129-71-7
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
Formula:
C31H40N8O3S
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
604.77
Ref: TM-T16422
| 1mg | 48.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 535.00 € | ||
| 100mg | 753.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Parsaclisib
CAS:1426698-88-5
Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 …
Formula:
C20H22ClFN6O2
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
432.88
Ref: TM-T12367
| 1mg | 145.00 € | ||
| 5mg | 305.00 € | ||
| 10mg | 495.00 € | ||
| 25mg | 805.00 € | ||
| 50mg | 1,111.00 € | ||
| 100mg | 1,501.00 € | ||
| 1mL*10mM (DMSO) | 335.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
PI4KIIIbeta-IN-10
CAS:1881233-39-1
PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ (IC50 of 3.6 nM).
Formula:
C22H25N3O5S2
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
475.58
Ref: TM-T12468
| 1mg | 80.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 255.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 792.00 € | ||
| 200mg | 1,064.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
EGFR-IN-7
CAS:2267329-76-8
EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.
Formula:
C32H41BrN9O2P
Purity:
95.32% - 99.64%
Color and Shape:
Solid
Molecular weight:
694.6
Ref: TM-T11161
| 1mg | 97.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 376.00 € | ||
| 25mg | 642.00 € | ||
| 50mg | 914.00 € | ||
| 100mg | 1,216.00 € | ||
| 500mg | 2,460.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Lapatinib
CAS:231277-92-2
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.
Formula:
C29H26ClFN4O4S
Purity:
99.00% - 99.81%
Color and Shape:
Powder
Molecular weight:
581.06
Ref: TM-T0078
| 10mg | 34.00 € | ||
| 25mg | 44.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 73.00 € | ||
| 200mg | 92.00 € | ||
| 500mg | 127.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
O-Desmethyl gefitinib
CAS:847949-49-9
O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed …
Formula:
C21H22ClFN4O3
Purity:
97.17%
Color and Shape:
Solid
Molecular weight:
432.88
Ref: TM-T16369
| 1mg | 56.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 343.00 € | ||
| 50mg | 547.00 € | ||
| 100mg | 783.00 € | ||
| 1mL*10mM (DMSO) | 120.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
NV-5138
CAS:2095886-80-7
NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.Cost-effective and …
Formula:
C7H13F2NO2
Purity:
98% - ≥98%
Color and Shape:
Solid
Molecular weight:
181.18
Ref: TM-T12270
| 1mg | 89.00 € | ||
| 5mg | 215.00 € | ||
| 10mg | 344.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,169.00 € | ||
| 100mg | 1,691.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
BRD0705
CAS:2056261-41-5
BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.
Formula:
C20H23N3O
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
321.42
Ref: TM-T10606
| 1mg | 89.00 € | ||
| 5mg | 183.00 € | ||
| 10mg | 266.00 € | ||
| 25mg | 395.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 742.00 € | ||
| 1mL*10mM (DMSO) | 200.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Khellin
CAS:82-02-0
Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.
Formula:
C14H12O5
Purity:
99.85% - 99.95%
Color and Shape:
Light Yellow Crystalline
Molecular weight:
260.24
Ref: TM-T1431
| 10mg | 38.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 74.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
PI4KIIIbeta-IN-9
CAS:1429624-84-9
PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). .
Formula:
C23H25N3O5S2
Purity:
97.18%
Color and Shape:
Solid
Molecular weight:
487.59
Ref: TM-T12469
| 1mg | 80.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 283.00 € | ||
| 25mg | 512.00 € | ||
| 50mg | 715.00 € | ||
| 100mg | 938.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Cyanoacetohydrazide
CAS:140-87-4
Cyanoacetohydrazide (Cyanoacetic hydrazide) is an anti-TB drug. It has also been used to derive compounds …
Formula:
C3H5N3O
Purity:
99.78%
Color and Shape:
Stout Prisms From Alcohol Slightly Brown Powder
Molecular weight:
99.09
Ref: TM-T0704
| 1g | 34.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
MELK-IN-1
CAS:2095596-44-2
MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 …
Formula:
C31H33N5O4
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
539.62
Ref: TM-T11997
| 1mg | 35.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 104.00 € | ||
| 25mg | 202.00 € | ||
| 50mg | 329.00 € | ||
| 100mg | 540.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Epertinib hydrochloride
CAS:2071195-74-7
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity.
Formula:
C30H28Cl2FN5O3
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
596.48
Ref: TM-T11213
| 1mg | 92.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 311.00 € | ||
| 25mg | 533.00 € | ||
| 50mg | 755.00 € | ||
| 100mg | 1,017.00 € | ||
| 500mg | 2,043.00 € | ||
| 1mL*10mM (DMSO) | 255.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Rociletinib
CAS:1374640-70-6
Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor …
Formula:
C27H28F3N7O3
Purity:
98.39% - 99.25%
Color and Shape:
Solid
Molecular weight:
555.55
Ref: TM-T2369
| 5mg | 49.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 124.00 € | ||
| 100mg | 197.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
NSC781406
CAS:1676893-24-5
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
Formula:
C29H27F2N5O5S2
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
627.68
Ref: TM-T16355
| 2mg | 42.00 € | ||
| 5mg | 64.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 168.00 € | ||
| 50mg | 245.00 € | ||
| 100mg | 375.00 € | ||
| 200mg | 533.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Mevastatin
CAS:73573-88-3
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium …
Formula:
C23H34O5
Purity:
99.12%
Color and Shape:
White-Yellowish To Yellow Powder Solid Powder
Molecular weight:
390.51
Ref: TM-T0683
| 50mg | 56.00 € | ||
| 100mg | 85.00 € | ||
| 500mg | 212.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
Erlotinib hydrochloride
CAS:183319-69-9
Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for …
Formula:
C22H23N3O4·HCl
Purity:
99.78% - 99.85%
Color and Shape:
White Or Off-White Powder
Molecular weight:
429.9
Ref: TM-T0373L
| 1g | 116.00 € | ||
| 50mg | 42.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 84.00 € | ||
| 1mL*10mM (DMSO) | 65.00 € |
Estimated delivery in United States, on Wednesday 30 Apr 2025
