PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
PS10
CAS:1564265-82-2
PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of …
Formula:
C14H13NO6S
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
323.32
Ref: TM-T12566
| 1mg | 40.00 € | ||
| 2mg | To inquire |
Estimated delivery in United States, on Monday 14 Apr 2025
Isoprenaline hydrochloride
CAS:51-30-9
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac …
Formula:
C11H18ClNO3
Purity:
98% - 99.25%
Color and Shape:
Turn Brownish-Pink Upon Prolonged Exposure To Air (Ntp 1992)
Molecular weight:
247.719
Ref: TM-T1056
| 1g | 39.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Erlotinib
CAS:183321-74-6
Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment …
Formula:
C22H23N3O4
Purity:
98.19% - 99.98%
Color and Shape:
White To Off-White Powder
Molecular weight:
393.44
Ref: TM-T0373
| 50mg | 48.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 79.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
PI4KIIIbeta-IN-10
CAS:1881233-39-1
PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ (IC50 of 3.6 nM).
Formula:
C22H25N3O5S2
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
475.58
Ref: TM-T12468
| 1mg | 80.00 € | ||
| 5mg | 164.00 € | ||
| 10mg | 255.00 € | ||
| 25mg | 420.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 792.00 € | ||
| 200mg | 1,064.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Lapatinib Ditosylate
CAS:388082-77-7
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for …
Formula:
C29H26ClFN4O4S·2C7H8O3S
Purity:
99.41%
Color and Shape:
Yellow Solid
Molecular weight:
925.46
Ref: TM-T6235
| 1g | 147.00 € | ||
| 25mg | 47.00 € | ||
| 50mg | 58.00 € | ||
| 100mg | 73.00 € | ||
| 200mg | 95.00 € | ||
| 500mg | 128.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
MK8722
CAS:1394371-71-1
MK8722 is an effective and systemic activator of pan-AMPK.
Formula:
C24H20ClN3O4
Purity:
98.08% - 99.88%
Color and Shape:
Solid
Molecular weight:
449.89
Ref: TM-T16099
| 1mg | 37.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 79.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 226.00 € | ||
| 50mg | 419.00 € | ||
| 100mg | 617.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Mutated EGFR-IN-1
CAS:1421372-66-8
Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, …
Formula:
C25H31N7O
Purity:
98.91%
Color and Shape:
Solid
Molecular weight:
445.56
Ref: TM-T16162
| 25mg | 58.00 € | ||
| 50mg | 66.00 € | ||
| 100mg | 89.00 € | ||
| 200mg | 116.00 € | ||
| 500mg | 187.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
IPI-3063
CAS:1425043-73-7
IPI-3063 is an effective and selective inhibitor of PI3K p110δ (IC50: 2.5 ± 1.2 nM).
Formula:
C25H25N7O2
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
455.51
Ref: TM-T15592
| 1mg | 47.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 104.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 340.00 € | ||
| 50mg | 472.00 € | ||
| 100mg | 645.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Lapatinib ditosylate monohydrate
CAS:388082-78-8
Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.
Formula:
C29H26ClFN4O4S·2(C7H8O3S)·H2O
Purity:
98% - 99.41%
Color and Shape:
Colourless To Light-Yellow Crystal
Molecular weight:
943.47
Ref: TM-T0078L
| 50mg | 52.00 € | ||
| 100mg | 70.00 € | ||
| 200mg | 94.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
NV-5138
CAS:2095886-80-7
NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.Cost-effective and …
Formula:
C7H13F2NO2
Purity:
98% - ≥98%
Color and Shape:
Solid
Molecular weight:
181.18
Ref: TM-T12270
| 1mg | 89.00 € | ||
| 5mg | 215.00 € | ||
| 10mg | 344.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,169.00 € | ||
| 100mg | 1,691.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Epertinib hydrochloride
CAS:2071195-74-7
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity.
Formula:
C30H28Cl2FN5O3
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
596.48
Ref: TM-T11213
| 1mg | 92.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 311.00 € | ||
| 25mg | 533.00 € | ||
| 50mg | 755.00 € | ||
| 100mg | 1,017.00 € | ||
| 500mg | 2,043.00 € | ||
| 1mL*10mM (DMSO) | 255.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Pyrotinib dimaleate
CAS:1397922-61-0
Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor, respectively, for the treatment of HER2-positive breast …
Formula:
C40H39ClN6O11
Purity:
98.07% - 99.52%
Color and Shape:
Solid
Molecular weight:
815.22
Ref: TM-T12594
| 1mg | 155.00 € | ||
| 5mg | 457.00 € | ||
| 10mg | 610.00 € | ||
| 25mg | 947.00 € | ||
| 50mg | 1,301.00 € | ||
| 100mg | 1,758.00 € | ||
| 1mL*10mM (DMSO) | 620.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Rociletinib
CAS:1374640-70-6
Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor …
Formula:
C27H28F3N7O3
Purity:
98.39% - 99.25%
Color and Shape:
Solid
Molecular weight:
555.55
Ref: TM-T2369
| 5mg | 49.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 99.00 € | ||
| 50mg | 124.00 € | ||
| 100mg | 197.00 € | ||
| 1mL*10mM (DMSO) | 58.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
P110δ-IN-1
CAS:1595129-71-7
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
Formula:
C31H40N8O3S
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
604.77
Ref: TM-T16422
| 1mg | 48.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 535.00 € | ||
| 100mg | 753.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Lapatinib
CAS:231277-92-2
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.
Formula:
C29H26ClFN4O4S
Purity:
99.00% - 99.81%
Color and Shape:
Powder
Molecular weight:
581.06
Ref: TM-T0078
| 10mg | 34.00 € | ||
| 25mg | 44.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 73.00 € | ||
| 200mg | 92.00 € | ||
| 500mg | 127.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Khellin
CAS:82-02-0
Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.
Formula:
C14H12O5
Purity:
99.85% - 99.95%
Color and Shape:
Light Yellow Crystalline
Molecular weight:
260.24
Ref: TM-T1431
| 10mg | 38.00 € | ||
| 25mg | 51.00 € | ||
| 50mg | 74.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Mevastatin
CAS:73573-88-3
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium …
Formula:
C23H34O5
Purity:
99.12%
Color and Shape:
White-Yellowish To Yellow Powder Solid Powder
Molecular weight:
390.51
Ref: TM-T0683
| 50mg | 56.00 € | ||
| 100mg | 85.00 € | ||
| 500mg | 212.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
CGS 15943
CAS:104615-18-1
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.
Formula:
C13H8ClN5O
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
285.69
Ref: TM-T14944
| 1mg | 47.00 € | ||
| 5mg | 89.00 € | ||
| 10mg | 131.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 474.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
STL127705
CAS:1326852-06-5
STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.
Formula:
C22H20FN5O4
Purity:
97.41% - 99.18%
Color and Shape:
Solid
Molecular weight:
437.42
Ref: TM-T13017
| 1mg | 114.00 € | ||
| 5mg | 274.00 € | ||
| 10mg | 432.00 € | ||
| 25mg | 715.00 € | ||
| 50mg | 1,008.00 € | ||
| 100mg | 1,359.00 € | ||
| 500mg | 2,717.00 € | ||
| 1mL*10mM (DMSO) | 316.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
PI4KIIIbeta-IN-9
CAS:1429624-84-9
PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ(IC50 of 7 nM). .
Formula:
C23H25N3O5S2
Purity:
97.18%
Color and Shape:
Solid
Molecular weight:
487.59
Ref: TM-T12469
| 1mg | 80.00 € | ||
| 5mg | 188.00 € | ||
| 10mg | 283.00 € | ||
| 25mg | 512.00 € | ||
| 50mg | 715.00 € | ||
| 100mg | 938.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
