PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
- AMPK(158 products)
- ATM/ATR(71 products)
- DNA-PK(51 products)
- EGFR(572 products)
- MELK(7 products)
- PDK(9 products)
- PI3K(242 products)
- S6 Kinase(9 products)
- gsk-3(112 products)
- mTOR(144 products)
Show 2 more subcategories
Found 1038 products of "PI3K/Akt/mTOR Signaling"
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Tenalisib
CAS:<p>Tenalisib (RP6530) (RP6530) is a potent and selective inhibitor of PI3Kδ and PI3Kγ(IC50 values of 25 and 33 nM, respectively.)</p>Formula:C23H18FN5O2Purity:99.71%Color and Shape:SolidMolecular weight:415.42Margetuximab
CAS:<p>Margetuximab (MGAH-22) is a second generation anti-HER2 monoclonal antibody with anti-tumor activity.</p>Purity:95.3% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.3% (SDS-PAGE); 99.3% (SEC-HPLC)Color and Shape:LiquidNSC781406
CAS:<p>NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).</p>Formula:C29H27F2N5O5S2Purity:99.58%Color and Shape:SolidMolecular weight:627.689-ING-41
CAS:<p>9-ING-41 is a glycogen synthase kinase-3 inhibitor.</p>Formula:C22H13FN2O5Purity:99.32%Color and Shape:SolidMolecular weight:404.35Indazole
CAS:<p>Indazole, a heterocyclic compound, offers diverse biological activities.</p>Formula:C7H6N2Purity:99.59% - 99.85%Color and Shape:White Or Beige Crystalline PowderMolecular weight:118.14Parsaclisib
CAS:<p>Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)</p>Formula:C20H22ClFN6O2Purity:98.59%Color and Shape:SolidMolecular weight:432.88Intetumumab
CAS:<p>Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.</p>Purity:97.6% (SDS-PAGE); 97.1% (SEC-HPLC) - 97.6% (SDS-PAGE); 97.1% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.6 (kDa)O-Desmethyl gefitinib
CAS:<p>O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.</p>Formula:C21H22ClFN4O3Purity:97.17%Color and Shape:SolidMolecular weight:432.88Petosemtamab
CAS:<p>Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.</p>Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:145.97 kDaErlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4·HClPurity:99.78% - 99.85%Color and Shape:White Or Off-White PowderMolecular weight:429.9LTURM34
CAS:<p>LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM.</p>Formula:C24H18N2O3SPurity:99.34%Color and Shape:SolidMolecular weight:414.48AV-412
CAS:<p>AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).</p>Formula:C41H44ClFN6O7S2Purity:99.85% - 99.92%Color and Shape:SolidMolecular weight:851.41Gancotamab
CAS:<p>Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.</p>Purity:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)Color and Shape:LiquidErlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4Purity:98.19% - 99.98%Color and Shape:White To Off-White PowderMolecular weight:393.44Lapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formula:C29H26ClFN4O4S·2C7H8O3SPurity:99.41%Color and Shape:Yellow SolidMolecular weight:925.46Barecetamab
CAS:<p>Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.</p>Purity:97.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidCyanoacetohydrazide
CAS:<p>Cyanoacetohydrazide (Cyanoacetic hydrazide) is an anti-TB drug. It has also been used to derive compounds that may have antitumor properties.</p>Formula:C3H5N3OPurity:99.78%Color and Shape:Stout Prisms From Alcohol Slightly Brown PowderMolecular weight:99.09Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurity:98% - 99.41%Color and Shape:Colourless To Light-Yellow CrystalMolecular weight:943.47MELK-IN-1
CAS:<p>MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).</p>Formula:C31H33N5O4Purity:99.84%Color and Shape:SolidMolecular weight:539.62BRD0705
CAS:<p>BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.</p>Formula:C20H23N3OPurity:99.01%Color and Shape:SolidMolecular weight:321.42
