PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
PS10
CAS:1564265-82-2
PS10 is a ATP-competitive inhibitor of pan-PDK(PDK2, PDK4, PDK1, and PDK3 with IC50 of 0.8 …
Formula:
C14H13NO6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
323.32
Ref: TM-T12566
| 1mg | 40.00 € | ||
| 2mg | To inquire |
Estimated delivery in United States, on Friday 29 Nov 2024
Lapatinib ditosylate monohydrate
CAS:388082-78-8
Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.
Formula:
C29H26ClFN4O4S·2(C7H8O3S)·H2O
Purity:
100% - 98%
Color and Shape:
Colourless To Light-Yellow Crystal
Molecular weight:
943.47
Ref: TM-T0078L
| 50mg | 52.00 € | ||
| 100mg | 69.00 € | ||
| 200mg | 92.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
BRD0705
CAS:2056261-41-5
BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.
Formula:
C20H23N3O
Purity:
99.59%
Color and Shape:
Solid
Molecular weight:
321.42
Ref: TM-T10606
| 1mg | 146.00 € | ||
| 2mg | 197.00 € | ||
| 5mg | 300.00 € | ||
| 10mg | 435.00 € | ||
| 25mg | 646.00 € | ||
| 50mg | 906.00 € | ||
| 100mg | 1,212.00 € | ||
| 1mL*10mM (DMSO) | 332.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Rilzabrutinib
CAS:1575596-29-0
Rilzabrutinib (PRN1008) is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase …
Formula:
C36H40FN9O3
Purity:
97.87% - 99.76%
Color and Shape:
Solid
Molecular weight:
665.76
Ref: TM-T12542
| 1mg | 95.00 € | ||
| 5mg | 227.00 € | ||
| 10mg | 363.00 € | ||
| 25mg | 631.00 € | ||
| 50mg | 909.00 € | ||
| 100mg | 1,273.00 € | ||
| 500mg | 2,545.00 € | ||
| 1mL*10mM (DMSO) | 332.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Erlotinib
CAS:183321-74-6
Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment …
Formula:
C22H23N3O4
Purity:
98.19% - 99.98%
Color and Shape:
White To Off-White Powder
Molecular weight:
393.44
Ref: TM-T0373
| 50mg | 47.00 € | ||
| 100mg | 52.00 € | ||
| 500mg | 78.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Gefitinib
CAS:184475-35-2
Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 …
Formula:
C22H24ClFN4O3
Purity:
100% - 99.92%
Color and Shape:
Light-Yellow Crystalline Powder
Molecular weight:
446.9
Ref: TM-T1181
| 1g | 80.00 € | ||
| 5g | 144.00 € | ||
| 100mg | 54.00 € | ||
| 500mg | 62.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
MELK-IN-1
CAS:2095596-44-2
MELK-IN-1 (MELK inhibitor 17) is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 …
Formula:
C31H33N5O4
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
539.62
Ref: TM-T11997
| 1mg | 36.00 € | ||
| 5mg | 70.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 200.00 € | ||
| 50mg | 326.00 € | ||
| 100mg | 534.00 € | ||
| 1mL*10mM (DMSO) | 84.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Allitinib
CAS:897383-62-9
Allitinib (AST-1306) (AST-1306) has anti-cancer activity,and it is an irreversible EGFR and ErbB2 inhibitor with …
Formula:
C24H18ClFN4O2
Purity:
99.10% - 99.28%
Color and Shape:
Solid
Molecular weight:
448.88
Ref: TM-T14336
| 1mg | 51.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 318.00 € | ||
| 50mg | 476.00 € | ||
| 100mg | 675.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Parsaclisib
CAS:1426698-88-5
Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 …
Formula:
C20H22ClFN6O2
Purity:
98.59%
Color and Shape:
Solid
Molecular weight:
432.88
Ref: TM-T12367
| 1mg | 143.00 € | ||
| 5mg | 299.00 € | ||
| 10mg | 485.00 € | ||
| 25mg | 788.00 € | ||
| 50mg | 1,087.00 € | ||
| 100mg | 1,473.00 € | ||
| 1mL*10mM (DMSO) | 334.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Cyanoacetohydrazide
CAS:140-87-4
Cyanoacetohydrazide (Cyanoacetic hydrazide) is an anti-TB drug. It has also been used to derive compounds …
Formula:
C3H5N3O
Purity:
99.9%
Color and Shape:
Stout Prisms From Alcohol Slightly Brown Powder
Molecular weight:
99.09
Ref: TM-T0704
| 1g | 34.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Pyrotinib dimaleate
CAS:1397922-61-0
Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor, respectively, for the treatment of HER2-positive breast …
Formula:
C40H39ClN6O11
Purity:
98.07% - 99.52%
Color and Shape:
Solid
Molecular weight:
815.22
Ref: TM-T12594
| 1mg | 151.00 € | ||
| 5mg | 448.00 € | ||
| 10mg | 596.00 € | ||
| 25mg | 925.00 € | ||
| 50mg | 1,272.00 € | ||
| 100mg | 1,729.00 € | ||
| 1mL*10mM (DMSO) | 616.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
NSC781406
CAS:1676893-24-5
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
Formula:
C29H27F2N5O5S2
Purity:
99.58%
Color and Shape:
Solid
Molecular weight:
627.68
Ref: TM-T16355
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 164.00 € | ||
| 50mg | 238.00 € | ||
| 100mg | 365.00 € | ||
| 200mg | 520.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Isoprenaline hydrochloride
CAS:51-30-9
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac …
Formula:
C11H18ClNO3
Purity:
100% - 98%
Color and Shape:
Turn Brownish-Pink Upon Prolonged Exposure To Air (Ntp 1992)
Molecular weight:
247.719
Ref: TM-T1056
| 1g | 44.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Epertinib hydrochloride
CAS:2071195-74-7
Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity.
Formula:
C30H28Cl2FN5O3
Purity:
99.14%
Color and Shape:
Solid
Molecular weight:
596.48
Ref: TM-T11213
| 1mg | 91.00 € | ||
| 5mg | 186.00 € | ||
| 10mg | 308.00 € | ||
| 25mg | 527.00 € | ||
| 50mg | 746.00 € | ||
| 100mg | 1,004.00 € | ||
| 500mg | 2,016.00 € | ||
| 1mL*10mM (DMSO) | 252.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
IPI-3063
CAS:1425043-73-7
IPI-3063 is an effective and selective inhibitor of PI3K p110δ (IC50: 2.5 ± 1.2 nM).
Formula:
C25H25N7O2
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
455.51
Ref: TM-T15592
| 1mg | 46.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 171.00 € | ||
| 25mg | 333.00 € | ||
| 50mg | 462.00 € | ||
| 100mg | 630.00 € | ||
| 1mL*10mM (DMSO) | 113.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Lapatinib
CAS:231277-92-2
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.
Formula:
C29H26ClFN4O4S
Purity:
99.03% - 99.89%
Color and Shape:
Powder
Molecular weight:
581.06
Ref: TM-T0078
| 10mg | 40.00 € | ||
| 25mg | 49.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 77.00 € | ||
| 200mg | 95.00 € | ||
| 500mg | 129.00 € | ||
| 1mL*10mM (DMSO) | 36.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
GSK-3β inhibitor 1
CAS:187325-53-7
GSK-3β inhibitor 1 is an inhibitor of GSK-3β( IC50 of 4.9 nM) and demonstrates high …
Formula:
C14H10N2O
Purity:
99.08%
Color and Shape:
Solid
Molecular weight:
222.24
Ref: TM-T11467
| 1mg | 77.00 € | ||
| 5mg | 162.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 458.00 € | ||
| 50mg | 671.00 € | ||
| 100mg | 926.00 € | ||
| 200mg | 724.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Cromolyn sodium
CAS:15826-37-6
Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical …
Formula:
C23H14Na2O11
Purity:
98.25% - 99.95%
Color and Shape:
Colorless Crystals From Ethanol + Ether White Crystalline Powder
Molecular weight:
512.33
Ref: TM-T1260
| 1g | 52.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
AV-412
CAS:451493-31-5
AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 …
Formula:
C41H44ClFN6O7S2
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
851.41
Ref: TM-T10419
| 1mg | 43.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 248.00 € | ||
| 50mg | 415.00 € | ||
| 100mg | 604.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
Mevastatin
CAS:73573-88-3
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium …
Formula:
C23H34O5
Purity:
97.96%
Color and Shape:
White-Yellowish To Yellow Powder Solid Powder
Molecular weight:
390.51
Ref: TM-T0683
| 50mg | 55.00 € | ||
| 100mg | 83.00 € | ||
| 500mg | 207.00 € | ||
| 1mL*10mM (DMSO) | 59.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
