PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
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Subcategories of "PI3K/Akt/mTOR Signaling"
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Products of "PI3K/Akt/mTOR Signaling"
FD274
CAS:2641899-38-7
FD274 is a potent dual PI3K/mTOR inhibitor with inhibitory effects on PI3Kα/β/γ/δ and mTOR, with …
Formula:
C22H14ClFN6O2S
Purity:
98%
Color and Shape:
Soild
Molecular weight:
480.9
Ref: TM-T77629
| 1mg | 184.00 € | ||
| 5mg | 405.00 € | ||
| 10mg | 612.00 € | ||
| 25mg | 1,044.00 € | ||
| 50mg | 1,580.00 € | ||
| 100mg | 2,388.00 € | ||
| 500mg | 5,254.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
PI3Kδ-IN-12
PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities …
Formula:
C20H15Cl2N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
444.27
Ref: TM-T78691
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
HTH-02-006
HTH-02-006, a NUAK2 inhibitor (IC50 = 126 nM), decreases phosphorylated MYPT1 levels in HuCCT-1 cells …
Formula:
C25H29IN6O3
Purity:
98%
Color and Shape:
Soild
Molecular weight:
588.45
Ref: TM-T82165
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Monday 2 Dec 2024
GSK-3 inhibitor 3
CAS:2227279-84-5
GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and …
Formula:
C23H15FN6O
Purity:
98.36%
Color and Shape:
Soild
Molecular weight:
410.4
Ref: TM-T77342
| 1mg | 183.00 € | ||
| 5mg | 400.00 € | ||
| 10mg | 591.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,262.00 € | ||
| 100mg | 1,706.00 € | ||
| 500mg | 3,418.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
CHIR 98024
CAS:556813-39-9
CHIR 98024: strong GSK-3α/β blocker, IC50 0.65/0.58 nM, selective over Cdc2/ERK2.
Formula:
C20H17Cl2N9O2
Purity:
96.74%
Color and Shape:
Solid
Molecular weight:
486.31
Ref: TM-T3074
| 1mg | 43.00 € | ||
| 2mg | 54.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 293.00 € | ||
| 50mg | 477.00 € | ||
| 100mg | 693.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
PDK1-IN-RS2
CAS:1643958-89-7
PDK1-IN-RS2, a PIFtide mimic, selectively inhibits PDK1, blocking S6K1 activation (Kd: 9 μM).
Formula:
C15H9ClN2O2S3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
380.89
Ref: TM-T16450
| 1mL*10mM (DMSO) | 173.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Rapalink-1
CAS:1887095-82-0
Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.
Formula:
C91H138N12O24
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1784.14
Ref: TM-TP2288
| 5mg | 550.00 € | ||
| 25mg | 1,563.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
mTOR inhibitor-8
CAS:2489196-70-3
mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer with antiviral and antitumor activity for …
Formula:
C24H19ClN4OS
Purity:
98.11%
Color and Shape:
Liquid
Molecular weight:
446.95
Ref: TM-T36316
| 1mg | 51.00 € | ||
| 5mg | 107.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 345.00 € | ||
| 50mg | 564.00 € | ||
| 100mg | 904.00 € | ||
| 1mL*10mM (DMSO) | 112.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells …
Color and Shape:
Liquid
Molecular weight:
60-90 KDa (reducing condition)
Ref: TM-TMPJ-00646
| 20µg | 356.00 € | ||
| 100µg | 945.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Amivantamab
CAS:2171511-58-1
Amivantamab (JNJ-61186372) is an antibody that recognizes EGFR and MET and has anticancer and antitumor …
Purity:
SDS-PAGE:>95%;SEC-HPLC:97.24%
Color and Shape:
Liquid
Molecular weight:
145.88 kDa
Ref: TM-T77110
| 1mg | 270.00 € | ||
| 5mg | 734.00 € | ||
| 10mg | 1,174.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, …
Color and Shape:
Liquid
Molecular weight:
41.6 kDa (predicted)
Ref: TM-TMPK-00689
| 1mg | 5,901.00 € | ||
| 100µg | 1,374.00 € | ||
| 500µg | 3,535.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Gefitinib hydrochloride
CAS:184475-55-6
Gefitinib hydrochloride (ZD-1839 hydrochloride) is an EGFR inhibitor with antitumor activity, inhibits EGF-stimulated tumor cell …
Formula:
C22H25Cl2FN4O3
Color and Shape:
Solid
Molecular weight:
483.36
Ref: TM-T1181L
| 50mg | 39.00 € | ||
| 100mg | 51.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, …
Color and Shape:
Solid
Molecular weight:
41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00690
| 1mg | 5,919.00 € | ||
| 100µg | 1,378.00 € | ||
| 500µg | 3,546.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with …
Color and Shape:
Liquid
Molecular weight:
71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00425
| 1mg | 5,919.00 € | ||
| 100µg | 1,378.00 € | ||
| 500µg | 3,546.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Osimertinib dimesylate
CAS:2070014-82-1
Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM …
Formula:
C30H41N7O8S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
691.82
Ref: TM-T10433
| 2mg | 35.00 € | ||
| 5mg | 46.00 € | ||
| 10mg | 60.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Rilematovir
CAS:1383450-81-4
Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.
Formula:
C21H20ClF3N4O3S
Purity:
99.82%
Color and Shape:
Solid
Molecular weight:
500.92
Ref: TM-T15621
| 5mg | 47.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 129.00 € | ||
| 50mg | 185.00 € | ||
| 100mg | 273.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
EGFR Protein, Human, Recombinant (His & Avi)
EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi …
Color and Shape:
Liquid
Molecular weight:
71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00426
| 1mg | 2,661.00 € | ||
| 100µg | 419.00 € | ||
| 500µg | 1,587.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Cbz-B3A
CAS:1884710-81-9
Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) …
Formula:
C35H58N6O9
Purity:
98.63%
Color and Shape:
Solid
Molecular weight:
706.87
Ref: TM-T14886
| 1mg | 106.00 € | ||
| 2mg | 155.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 373.00 € | ||
| 25mg | 611.00 € | ||
| 50mg | 839.00 € | ||
| 100mg | 1,150.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
THZ-P1-2
CAS:2058075-45-7
THZ-P1-2 is a PI5P4K inhibitor with anti-leukemic activity and can be used in the study …
Formula:
C31H29N7O2
Color and Shape:
Liquid
Molecular weight:
531.61
Ref: TM-T39459
| 1mg | 143.00 € | ||
| 5mg | 347.00 € | ||
| 10mg | 540.00 € | ||
| 25mg | 921.00 € | ||
| 50mg | 1,259.00 € | ||
| 100mg | 1,707.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Ceftriaxone Sodium
CAS:958633-51-7
Ceftriaxone Sodium is a sporotaxin antibiotic that inhibits GSK3β and Aurora B. It is used …
Formula:
C18H17N8NaO7S3
Color and Shape:
Liquid
Molecular weight:
576.562
Ref: TM-T66175
| 1g | 264.00 € | ||
| 25mg | 46.00 € | ||
| 50mg | 59.00 € | ||
| 100mg | 85.00 € | ||
| 500mg | 178.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
