PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 231 products for "PI3K".
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740 Y-P acetate
740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-Formula:C143H226N43O41PS3Purity:99.92%Color and Shape:SoildMolecular weight:3330.79PI3Kδ-IN-12
PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities with pKi values of 8.0 for PI3Kδ, 6.5 for PI3Kγ, 6.4Formula:C20H15Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:444.27GSK251
CAS:GSK251 is a novel, orally bioavailable inhibitor of PI3Kδ, exhibiting high potency and selectivity, with a unique binding mode.Formula:C29H37FN6O4SPurity:99.8%Color and Shape:White SolidMolecular weight:584.71(3S)-GSK-F1
CAS:(3S)-GSK-F1 is a selective small molecule inhibitor of Type III Phosphatidylinositol 4‑Kinase Alpha (PI4KIIIα), pIC50=8.3.Formula:C27H18F5N5O4SPurity:99.04%Color and Shape:SolidMolecular weight:603.52Ref: TM-T67837
1mg70.00€5mg133.00€1mL*10mM (DMSO)182.00€10mg210.00€25mg371.00€50mg532.00€100mg837.00€IHMT-PI3Kδ-372 S-isomer
CAS:IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM.Formula:C26H23F2N7O2Purity:99.97%Color and Shape:White SolidMolecular weight:503.5Ref: TM-T60196
1mg109.00€2mg163.00€5mg241.00€1mL*10mM (DMSO)294.00€10mg354.00€25mg532.00€50mg745.00€100mg1,018.00€Duvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor.Formula:C22H18Cl2N6OPurity:99.86% - 99.88%Color and Shape:White SolidMolecular weight:453.32Ref: TM-T11129L
1mg296.00€5mg718.00€1mL*10mM (DMSO)895.00€10mg982.00€25mg1,485.00€50mg2,008.00€100mg2,637.00€PROTAC PI3K/110β degrader-1
CAS:PROTACPI3K/110β degrader-1 (J-9) acts as a PROTAC degrader specifically targeting PI3K/110β.Formula:C51H65N9O9SColor and Shape:SolidMolecular weight:980.18PI3K-IN-46
CAS:PI3K-IN-46 is a specific inhibitor of PI3Kγ.Formula:C13H9N3OSPurity:97.26%Color and Shape:SolidMolecular weight:255.3Ref: TM-T64392
1mg62.00€1mL*10mM (DMSO)133.00€5mg149.00€10mg213.00€25mg319.00€50mg450.00€100mg605.00€ARUK2001607
CAS:ARUK2001607 selectively inhibits PI5P4Kγ (Kd=7.1 nM) with high selectivity over 150+ kinases.Formula:C14H13N3O2S2Purity:99.75%Color and Shape:SolidMolecular weight:319.40GSK2292767 FA
GSK2292767 FA: potent PI3Kδ inhibitor, pIC50=10.1, 500x selectivity, for respiratory research.Formula:C25H30N6O7SPurity:99.52%Color and Shape:SolidMolecular weight:558.61PI3K-IN-57
PI3K-IN-57 (Compound 4a) is a PI3K inhibitor that shows strong inhibitory effects on the proliferation of HeLa tumor ectopic xenografts in vivo. It holds promise for anticancer agent research.Color and Shape:Odour SolidPenetratin-PI3Kγ(126-150)
Penetratin-PI3Kγ(126-150) is a peptide inhibitor of PI3Kγ that plays a significant role in respiratory diseases.Formula:C229H362N76O57SColor and Shape:SolidMolecular weight:5120.74849IHMT-PI3K-315
IHMT-PI3K-315 (20e) serves as a potent, selective inhibitor of PI3Kγ/δ, exhibiting IC 50 values of 4.0 nM for PI3Kγ and 9.1 nM for PI3Kδ. Additionally, it demonstrates antitumor activity.Formula:C22H20F2N6O4Color and Shape:SolidMolecular weight:470.43Kinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Color and Shape:Odour SolidRef: TM-L1600
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireBAY1082439
CAS:BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2].Formula:C25H30N6O5Purity:98%Color and Shape:White SolidMolecular weight:494.54PI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withColor and Shape:Odour SolidRef: TM-L1300
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireUmbralisib R-enantiomer
CAS:Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202.Formula:C31H24F3N5O3Purity:97.34%Color and Shape:SolidMolecular weight:571.55Ref: TM-T13140
1mg177.00€5mg432.00€1mL*10mM (DMSO)532.00€10mg620.00€25mg1,108.00€50mg1,431.00€100mg1,783.00€PI3Kα-IN-25
PI3Kα-IN-25 (Compound Djh1) is a selective inhibitor of PI3Kα, suitable for research in triple-negative breast cancer.Formula:C21H19ClN4O4Color and Shape:SolidMolecular weight:426.853FDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.Color and Shape:LiquidRef: TM-L1610
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquirePI3K-IN-47
PI3K-IN-47 (Compound 27) is a potent bivalent inhibitor targeting the phosphoinositide 3-kinases (PI3K) family, exhibiting inhibitory concentration (IC50)Formula:C50H46F4N8O8S2Purity:98%Color and Shape:SolidMolecular weight:1027.07
