PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
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PI3Kδ-IN-18
Se15, a selective PI3Kδ inhibitor, exhibits potency with an IC50 value of less than 0.1nM …
Purity:
98%
Ref: TM-T81467
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WYE-687
CAS:1062161-90-3
WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR …
Formula:
C28H32N8O3
Purity:
98.98%
Color and Shape:
Solid
Molecular weight:
528.61
Ref: TM-T6732
| 5mg | 39.00 € | ||
| 10mg | 58.00 € | ||
| 25mg | 111.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARUK2001607
ARUK2001607 selectively inhibits PI5P4Kγ (Kd=7.1 nM) with high selectivity over 150+ kinases.
Formula:
C14H13N3O2S2
Purity:
99.86%
Color and Shape:
Soild
Molecular weight:
319.40
Ref: TM-T67845
| 5mg | 35.00 € | ||
| 10mg | 52.00 € | ||
| 25mg | 83.00 € | ||
| 50mg | 110.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3Kα-IN-14
PI3Kα-IN-14 (compound F8), a potent PI3Kα inhibitor, exhibits an IC50 value of 0.14 nM and …
Purity:
98%
Ref: TM-T81469
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
STX-478
CAS:2883540-92-7
STX-478 (compound 80), an orally administered, CNS-penetrant allosteric mutant-selective PI3Kα inhibitor, demonstrates significant and sustained …
Formula:
C16H12F5N5O2
Purity:
99.59%
Color and Shape:
Liquid
Molecular weight:
401.29
Ref: TM-T78211
| 1mg | 315.00 € | ||
| 5mg | 801.00 € | ||
| 10mg | 1,279.00 € | ||
| 25mg | 2,582.00 € | ||
| 50mg | 4,129.00 € | ||
| 1mL*10mM (DMSO) | 713.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Umbralisib R-enantiomer
CAS:1532533-69-9
Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer …
Formula:
C31H24F3N5O3
Purity:
95.61%
Color and Shape:
Solid
Molecular weight:
571.55
Ref: TM-T13140
| 1mg | 184.00 € | ||
| 5mg | 446.00 € | ||
| 10mg | 641.00 € | ||
| 25mg | 1,144.00 € | ||
| 50mg | 1,479.00 € | ||
| 100mg | 1,841.00 € | ||
| 1mL*10mM (DMSO) | 557.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3Kδ-IN-14
PI3Kδ-IN-14 (Compound (S)-29), a selective PI3Kδ inhibitor with an IC50 of 0.8 nM and a …
Formula:
C26H20ClFN8O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
514.94
Ref: TM-T79658
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SN32976
CAS:1246202-11-8
SN32976 is a pan PI3K inhibitor. SN32976 potently inhibited PI3K isoforms and mTOR, displaying preferential …
Formula:
C24H33F2N9O4S
Purity:
98.88%
Color and Shape:
Solid
Molecular weight:
581.64
Ref: TM-T9788
| 1mg | 111.00 € | ||
| 5mg | 241.00 € | ||
| 10mg | 356.00 € | ||
| 25mg | 543.00 € | ||
| 50mg | 760.00 € | ||
| 100mg | 1,018.00 € | ||
| 200mg | 1,358.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IHMT-PI3K-315
IHMT-PI3K-315 (20e) serves as a potent, selective inhibitor of PI3Kγ/δ, exhibiting IC 50 values of …
Formula:
C22H20F2N6O4
Color and Shape:
Liquid
Molecular weight:
470.43
Ref: TM-T200165
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3K-IN-41
PI3K-IN-41 (compound 2), a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties, demonstrates potent PI3K …
Formula:
C45H39F2N5O12S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
911.88
Ref: TM-T79566
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IHMT-PI3Kδ-372 S-isomer
CAS:2429889-61-0
IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM.
Formula:
C26H23F2N7O2
Purity:
99.68%
Color and Shape:
Soild
Molecular weight:
503.5
Ref: TM-T60196
| 1mg | 113.00 € | ||
| 2mg | 169.00 € | ||
| 5mg | 250.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 552.00 € | ||
| 50mg | 772.00 € | ||
| 100mg | 1,053.00 € | ||
| 1mL*10mM (DMSO) | 309.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI3Kδ-IN-12
PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities …
Formula:
C20H15Cl2N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
444.27
Ref: TM-T78691
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PH14
PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for …
Purity:
98%
Ref: TM-T81499
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
PI5P4Ks-IN-2
CAS:2766854-03-7
PI5P4Ks-IN-2 inhibits PI5P4K isoforms α, β, γ, γ+ with IC50 <4.3, <4.6, 6.2, 0.32 µM, …
Formula:
C22H23N5
Purity:
99.09% - 99.21%
Color and Shape:
Soild
Molecular weight:
357.45
Ref: TM-T72032
| 1mg | 157.00 € | ||
| 5mg | 330.00 € | ||
| 10mg | 491.00 € | ||
| 25mg | 829.00 € | ||
| 50mg | 1,086.00 € | ||
| 100mg | 1,420.00 € | ||
| 1mL*10mM (DMSO) | 361.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sonolisib
CAS:502632-66-8
Sonolisib is an irreversible and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), …
Formula:
C29H35NO8
Purity:
98%
Color and Shape:
Solid
Molecular weight:
525.59
Ref: TM-T16908
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 9f
CAS:1144075-42-2
mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for …
Formula:
C25H23N5O2S
Purity:
98.39%
Color and Shape:
Soild
Molecular weight:
457.55
Ref: TM-T67701
| 1mg | 184.00 € | ||
| 5mg | 445.00 € | ||
| 10mg | 609.00 € | ||
| 25mg | 922.00 € | ||
| 50mg | 1,238.00 € | ||
| 100mg | 1,629.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 9e
CAS:1144075-40-0
mTOR inhibitor 9e is a selective mTOR inhibitor with IC50 of 0.68nM and 1359nM for …
Formula:
C22H23N5O2S
Purity:
98.80%
Color and Shape:
Soild
Molecular weight:
421.52
Ref: TM-T67704
| 1mg | 187.00 € | ||
| 5mg | 453.00 € | ||
| 10mg | 617.00 € | ||
| 25mg | 936.00 € | ||
| 50mg | 1,257.00 € | ||
| 100mg | 1,653.00 € | ||
| 200mg | 2,239.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 13
CAS:1144075-44-4
Urea derivative; selective mTOR blocker; IC50: 0.29nM (mTOR), 119nM (PI3Kα).
Formula:
C24H22N6O2S
Purity:
99.24%
Color and Shape:
Solid
Molecular weight:
458.54
Ref: TM-T9310
| 1mg | 182.00 € | ||
| 5mg | 442.00 € | ||
| 10mg | 602.00 € | ||
| 25mg | 913.00 € | ||
| 50mg | 1,227.00 € | ||
| 100mg | 1,614.00 € | ||
| 200mg | 2,185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
mTOR inhibitor 9c
CAS:1144075-36-4
mTOR inhibitor 9c is a selective mTOR inhibitor with IC50 of 0.7nM and 825nM for …
Formula:
C21H22FN5O2S
Purity:
98.73%
Color and Shape:
Soild
Molecular weight:
427.5
Ref: TM-T67706
| 1mg | 182.00 € | ||
| 5mg | 442.00 € | ||
| 10mg | 602.00 € | ||
| 25mg | 913.00 € | ||
| 50mg | 1,227.00 € | ||
| 100mg | 1,614.00 € | ||
| 200mg | 2,185.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
IHMT-PI3K-455
IHMT-PI3K-455 (Compound 15u) is a potent, selective PI3Kγ/δ dual inhibitor, demonstrating oral activity, with IC50 …
Formula:
C26H21F2N7O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
517.49
Ref: TM-T78836
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
