PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 238 products for "PI3K".
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MSC2360844
CAS:MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).Formula:C26H27FN4O5SPurity:99.54% - 99.9%Color and Shape:SolidMolecular weight:526.58Ref: TM-T12115
1mg50.00€5mg110.00€1mL*10mM (DMSO)128.00€10mg172.00€25mg335.00€50mg538.00€100mg853.00€200mg1,144.00€Duvelisib (R enantiomer)
CAS:Duvelisib R enantiomer (IPI-145 R enantiomer) is an enantiomer of Duvelisib with lower activity. Duvelisib is a PI3K inhibitor.Formula:C22H17ClN6OPurity:98%Color and Shape:SolidMolecular weight:416.86PI3Kδ-IN-17
CAS:PI3Kδ-IN-17 (Compound S5) is a potent PI3K δ inhibitor, exhibiting an IC50 value of 2.82 nM and demonstrates significant efficacy in suppressing theFormula:C23H24F3N7O2Purity:98%Color and Shape:SolidMolecular weight:487.48PIK-inhibitors
CAS:PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.Formula:C19H17N5O2Purity:96.98%Color and Shape:SolidMolecular weight:347.37Ginsenoside Rk1
CAS:Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.Formula:C42H70O12Purity:98.46% - 99.13%Color and Shape:White SolidMolecular weight:767.00Ref: TM-T4S1499
1mg48.00€5mg87.00€10mg127.00€1mL*10mM (DMSO)129.00€25mg202.00€50mg299.00€100mg445.00€PI3Kδ-IN-1
CAS:PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM).Formula:C22H20F3N7O2Purity:99.85%Color and Shape:SolidMolecular weight:471.44CAL-130 Racemate
CAS:CAL-130 Racemate is the racemate of CAL-130. CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Formula:C23H22N8OPurity:98%Color and Shape:SolidMolecular weight:426.47PI3K-IN-51
CAS:PI3K-IN-51, characterized as a PI3K inhibitor, exhibits IC50 values below 500 nM for p120γ and p110δ/p85α (WO2016204429A1; Example 10) [1].Formula:C24H17Cl2N5O2Molecular weight:478.33NVP-QAV-572
CAS:NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).Formula:C17H19F2N7O3S2Purity:98%Color and Shape:SolidMolecular weight:471.5740 Y-P
CAS:740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!Formula:C141H222N43O39PS3Purity:98.3% - 99.87%Color and Shape:White SolidMolecular weight:3270.7PF-04979064
CAS:PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).Formula:C24H26N6O3Purity:99.98% - ≥98%Color and Shape:SolidMolecular weight:446.5GSK-F1
CAS:GSK-F1 (PI4KA inhibitor-F1) is a novel potent PI4KA inhibitor.Formula:C27H18F5N5O4SPurity:97.03%Color and Shape:SolidMolecular weight:603.52Ref: TM-T19840
1mg104.00€5mg215.00€1mL*10mM (DMSO)304.00€10mg318.00€25mg510.00€50mg692.00€100mg888.00€200mg1,251.00€PI3Kδ-IN-23
CAS:PI3Kδ-IN-23 (compound A11) is a potent inhibitor of PI3Kδ, with an IC50 of 0.27 nM. It binds to PI3Kδ through covalent interaction with Lys779 and plays a significant role in cancer research.Formula:C30H30N6O5Color and Shape:SolidMolecular weight:554.596PI3Kα-IN-19
CAS:PI3Kα-IN-19 (Compound 1) serves as an inhibitor of PI3Kα, specifically targeting the p110α catalytic subunit. PI3Kα, a frequently dysregulated kinase, is extensively utilized in cancer research [1].Formula:C28H28N6O3Molecular weight:496.56PI3Kδ-IN-27
CAS:PI3Kδ-IN-27 is a PI3Kδ inhibitor with an IC50 of 355.3 nM. It exhibits activity against SARS-CoV-2 and can be utilized in infection-related studies, such as those concerning COVID-19.Formula:C21H24N4O3Molecular weight:380.45PI3kδ inhibitor 1
CAS:PI3kδ inhibitor 1 is a selective inhibitor of PI3Kδ (IC50 of 3.8 nM).Formula:C28H33FN6O2Purity:98%Color and Shape:SolidMolecular weight:504.60UNI418
CAS:UNI418 is a dual inhibitor targeting PIKfyve and PIP5K1C, exhibiting antiviral activity against SARS-CoV-2 (EC50=1.4 μM). It inhibits the endocytosis of the virus mediated by ACE2 by suppressing PIP5K1C (IC50=60.1 nM; Kd=61 nM). Additionally, UNI418 impedes the entry of SARS-CoV-2 into host cells by inhibiting the proteolytic activation regulated by PIKfyve (Kd=0.78 nM).Formula:C22H16N6Color and Shape:SolidMolecular weight:364.40PI3Kγ inhibitor 1
CAS:PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ.Formula:C32H26N8O2SPurity:98%Color and Shape:SolidMolecular weight:586.67
