PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 238 products for "PI3K".
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ARUK2001607
CAS:ARUK2001607 selectively inhibits PI5P4Kγ (Kd=7.1 nM) with high selectivity over 150+ kinases.Formula:C14H13N3O2S2Purity:99.75%Color and Shape:SolidMolecular weight:319.40(3S)-GSK-F1
CAS:(3S)-GSK-F1 is a selective small molecule inhibitor of Type III Phosphatidylinositol 4‑Kinase Alpha (PI4KIIIα), pIC50=8.3.Formula:C27H18F5N5O4SPurity:99.04%Color and Shape:SolidMolecular weight:603.52Ref: TM-T67837
100mgTo inquire1mg70.00€5mg133.00€1mL*10mM (DMSO)182.00€10mg210.00€25mg371.00€50mg532.00€Umbralisib R-enantiomer
CAS:Umbralisib R-enantiomer (RP5264 R-enantiomer) is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202.Formula:C31H24F3N5O3Purity:97.34%Color and Shape:SolidMolecular weight:571.55Ref: TM-T13140
1mg177.00€5mg432.00€1mL*10mM (DMSO)532.00€10mg620.00€25mg1,108.00€50mg1,431.00€100mg1,783.00€PI3Kα-IN-25
PI3Kα-IN-25 (Compound Djh1) is a selective inhibitor of PI3Kα, suitable for research in triple-negative breast cancer.Formula:C21H19ClN4O4Color and Shape:SolidMolecular weight:426.853IHMT-PI3Kδ-372 S-isomer
CAS:IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM.Formula:C26H23F2N7O2Purity:99.97%Color and Shape:White SolidMolecular weight:503.5Ref: TM-T60196
1mg109.00€2mg163.00€5mg241.00€1mL*10mM (DMSO)294.00€10mg354.00€25mg532.00€50mg745.00€100mg1,018.00€STX-478
CAS:STX-478 (compound 80), an orally administered, CNS-penetrant allosteric mutant-selective PI3Kα inhibitor, demonstrates significant and sustained tumorFormula:C16H12F5N5O2Purity:98.31% - 99.78%Color and Shape:White SolidMolecular weight:401.29Ref: TM-T78211
1mg84.00€5mg177.00€1mL*10mM (DMSO)195.00€10mg286.00€25mg512.00€50mg772.00€100mg1,153.00€GSK251
CAS:GSK251 is a novel, orally bioavailable inhibitor of PI3Kδ, exhibiting high potency and selectivity, with a unique binding mode.Formula:C29H37FN6O4SPurity:99.8%Color and Shape:White SolidMolecular weight:584.71PI3K-IN-57
PI3K-IN-57 (Compound 4a) is a PI3K inhibitor that shows strong inhibitory effects on the proliferation of HeLa tumor ectopic xenografts in vivo. It holds promise for anticancer agent research.Color and Shape:Odour SolidPI3Kδ-IN-14
PI3Kδ-IN-14 (Compound (S)-29), a selective PI3Kδ inhibitor with an IC50 of 0.8 nM and a Kd of 84.8 nM, targets the ATP-binding site within the kinase domain ofFormula:C26H20ClFN8OPurity:98%Color and Shape:SolidMolecular weight:514.94PI3Kδ-IN-18
Se15, a selective PI3Kδ inhibitor, exhibits potency with an IC50 value of less than 0.1nM and is utilized in autoimmune research [1].Purity:98%Color and Shape:Odour SolidPF-06843195
CAS:PF-06843195 is a potent and selective PI3Kα inhibitor prevents it catalyzing the conversion of PIP2 to PIP3, inhibit the activation of AKT, anti-tumor .Formula:C20H25F3N8O4Purity:98.01%Color and Shape:White SolidMolecular weight:498.46PIP4K-IN-a131
CAS:PIP4K-IN-a131 is a PIP4K inhibitor with antiproliferative effects.Formula:C20H13N3Color and Shape:Yellow SolidMolecular weight:295.35740 Y-P(TFA)
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) is a potent and cell-permeable activator of PI3K.Formula:C143H223F3N43O41PS3Purity:99.78%Color and Shape:SolidMolecular weight:3384.73Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purity:99.66% - 99.96%Color and Shape:White SolidMolecular weight:696.82Ref: TM-T5S1982
1mg34.00€5mg73.00€10mg101.00€1mL*10mM (DMSO)102.00€25mg167.00€50mg240.00€100mg355.00€500mg845.00€GSK1059615
CAS:GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Formula:C18H11N3O2SPurity:99.3% - ≥95%Color and Shape:White SolidMolecular weight:333.36PIK-75 hydrochloride
CAS:PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.Formula:C16H14BrN5O4S·HClPurity:97.82% - 98%Color and Shape:SolidMolecular weight:488.74Glaucocalyxin A
CAS:Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.Formula:C20H28O4Purity:99.55% - 99.95%Color and Shape:White SolidMolecular weight:332.43PIK-108
CAS:PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).Formula:C22H24N2O3Purity:98.92%Color and Shape:SolidMolecular weight:364.44Ref: TM-T28416
1mg38.00€2mg54.00€5mg92.00€1mL*10mM (DMSO)100.00€10mg147.00€25mg241.00€50mg349.00€100mg482.00€200mg662.00€Esculetin
CAS:Esculetin: a coumarin from plants with anti-edema, anti-inflammatory, anti-tumor properties; inhibits LOs.Formula:C9H6O4Purity:98.03% - 99.76%Color and Shape:Yellow SolidMolecular weight:178.1415YS-49
CAS:YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).Formula:C20H20BrNO2Purity:99.65%Color and Shape:SolidMolecular weight:386.28Ref: TM-T13376
1mg46.00€2mg58.00€1mL*10mM (DMSO)92.00€5mg95.00€10mg137.00€25mg260.00€50mg386.00€100mg560.00€500mg1,153.00€
