PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Found 231 products for "PI3K".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
PI3Kα-IN-25
PI3Kα-IN-25 (Compound Djh1) is a selective inhibitor of PI3Kα, suitable for research in triple-negative breast cancer.Formula:C21H19ClN4O4Color and Shape:SolidMolecular weight:426.853740 Y-P acetate
740 Y-P acetate (740YPDGFR acetate) is a potent and cell-permeable PI3K activator.740 Y-P acetate tends to bind to GST fusion proteins containing the N- and C-Formula:C143H226N43O41PS3Purity:99.92%Color and Shape:SoildMolecular weight:3330.79IHMT-PI3Kδ-372 S-isomer
CAS:IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM.Formula:C26H23F2N7O2Purity:99.97%Color and Shape:White SolidMolecular weight:503.5Ref: TM-T60196
1mg109.00€2mg163.00€5mg241.00€1mL*10mM (DMSO)294.00€10mg354.00€25mg532.00€50mg745.00€100mg1,018.00€PROTAC PI3K/110β degrader-1
CAS:PROTACPI3K/110β degrader-1 (J-9) acts as a PROTAC degrader specifically targeting PI3K/110β.Formula:C51H65N9O9SColor and Shape:SolidMolecular weight:980.18D-106669
CAS:D-106669 (comppun 150) is a potent inhibitor of PI3Kα, with an IC50 value of 0.129 μM, and plays a significant role in cancer research.Formula:C17H18N6OColor and Shape:SolidMolecular weight:322.36GSK251
CAS:GSK251 is a novel, orally bioavailable inhibitor of PI3Kδ, exhibiting high potency and selectivity, with a unique binding mode.Formula:C29H37FN6O4SPurity:99.8%Color and Shape:White SolidMolecular weight:584.71PI3Kδ-IN-12
PI3Kδ-IN-12 (compound 13), a PI3Kδ inhibitor with a pIC50 of 5.8, exhibits differential binding affinities with pKi values of 8.0 for PI3Kδ, 6.5 for PI3Kγ, 6.4Formula:C20H15Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:444.27PF-06843195
CAS:PF-06843195 is a potent and selective PI3Kα inhibitor prevents it catalyzing the conversion of PIP2 to PIP3, inhibit the activation of AKT, anti-tumor .Formula:C20H25F3N8O4Purity:98.01%Color and Shape:White SolidMolecular weight:498.46TGX-221
CAS:TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110β catalytic subunit, is utilized for cancer treatment.Formula:C21H24N4O2Purity:99.60% - >99.99%Color and Shape:White SolidMolecular weight:364.44Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purity:99.66% - 99.96%Color and Shape:White SolidMolecular weight:696.82Ref: TM-T5S1982
1mg34.00€5mg73.00€10mg101.00€1mL*10mM (DMSO)102.00€25mg167.00€50mg240.00€100mg355.00€500mg845.00€GSK1059615
CAS:GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Formula:C18H11N3O2SPurity:99.3% - ≥95%Color and Shape:White SolidMolecular weight:333.36Glaucocalyxin A
CAS:Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.Formula:C20H28O4Purity:99.55% - 99.80%Color and Shape:White SolidMolecular weight:332.43PIK-108
CAS:PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).Formula:C22H24N2O3Purity:98.92%Color and Shape:SolidMolecular weight:364.44Ref: TM-T28416
1mg38.00€2mg54.00€5mg92.00€1mL*10mM (DMSO)100.00€10mg147.00€25mg241.00€50mg349.00€100mg482.00€200mg662.00€Esculetin
CAS:Esculetin: a coumarin from plants with anti-edema, anti-inflammatory, anti-tumor properties; inhibits LOs.Formula:C9H6O4Purity:98.03% - 99.76%Color and Shape:Yellow Crystalline PowderMolecular weight:178.14Brevianamide F
CAS:Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines.Formula:C16H17N3O2Purity:97.30% - 98.82%Color and Shape:SolidMolecular weight:283.33PIK-75 hydrochloride
CAS:PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.Formula:C16H14BrN5O4S·HClPurity:97.82%Color and Shape:SolidMolecular weight:488.74NIBR-17
CAS:NIBR-17 is a pan class I PI3K inhibitor. NIBR-17 inhibits PI3KKα, PI3KKβ, PI3KKγ, and PI3KKδ with IC50 of 1 nM, 9.2 nM, 9 nM, and 20 nM respectively.Formula:C18H20N8O2Purity:97.79%Color and Shape:White SolidMolecular weight:380.4Ref: TM-T22377
1mg71.00€5mg131.00€1mL*10mM (DMSO)155.00€10mg188.00€25mg303.00€50mg411.00€100mg532.00€YS-49
CAS:YS-49 is an activator of PI3K/Akt (a downstream target of RhoA).Formula:C20H20BrNO2Purity:99.65%Color and Shape:SolidMolecular weight:386.28Ref: TM-T13376
1mg46.00€2mg58.00€1mL*10mM (DMSO)92.00€5mg95.00€10mg137.00€25mg260.00€50mg386.00€100mg560.00€500mg1,153.00€ETP-46321
CAS:ETP-46321 is an effective and orally bioavailable PI3Kα/PI3Kδ inhibitor (Ki: 2.3/14.2 nM).Formula:C20H27N9O3SPurity:99.8%Color and Shape:SolidMolecular weight:473.55Ref: TM-TQ0229
1mg37.00€5mg82.00€1mL*10mM (DMSO)86.00€10mg116.00€25mg212.00€50mg298.00€100mg408.00€200mg552.00€1-Deoxynojirimycin hydrochloride
CAS:1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves.Formula:C6H14ClNO4Purity:99.88%Color and Shape:SolidMolecular weight:199.63
