PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
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Umbralisib hydrochloride
CAS:1532533-78-0
Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.
Formula:
C31H25ClF3N5O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
608.01
Ref: TM-T17066
| 2mg | 57.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
HS-173
CAS:1276110-06-5
HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).
Formula:
C21H18N4O4S
Purity:
99.33% - 99.64%
Color and Shape:
Solid
Molecular weight:
422.46
Ref: TM-T2308
| 1mg | 40.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 120.00 € | ||
| 25mg | 214.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 514.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Serabelisib
CAS:1268454-23-4
Serabelisib (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).
Formula:
C19H17N5O3
Purity:
95.12% - 99.5%
Color and Shape:
Solid
Molecular weight:
363.37
Ref: TM-T3153
| 1mg | 44.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 113.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 508.00 € | ||
| 500mg | 1,086.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
TG100-115
CAS:677297-51-7
TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.
Formula:
C18H14N6O2
Purity:
100% - 98.95%
Color and Shape:
Solid
Molecular weight:
346.34
Ref: TM-T2672
| 1mg | 42.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 373.00 € | ||
| 100mg | 581.00 € | ||
| 500mg | 1,189.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Sophocarpine
CAS:6483-15-4
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
Formula:
C15H22N2O
Purity:
98.67%
Color and Shape:
Solid
Molecular weight:
246.35
Ref: TM-T6677
| 5mg | 49.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 200.00 € | ||
| 100mg | 300.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Quercetin Dihydrate
CAS:6151-25-3
Quercetin Dihydrate (Sophoretin) is a flavonoid natural product that activates or inhibits the activity of …
Formula:
C15H10O7·2H2O
Purity:
97.03% - 97.77%
Color and Shape:
Yellow Solid
Molecular weight:
338.27
Ref: TM-T6630
| 500mg | 55.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
25(R,S)-Ruscogenin
CAS:874485-32-2
25(R,S)-Ruscogenin is able to regulate the PI3K/Akt/mTOR signalling pathway, and hinder the metastasis of hepatocellular …
Formula:
C27H42O4
Purity:
99.32% - 99.89%
Color and Shape:
Solid
Molecular weight:
430.62
Ref: TM-T5740
| 1mg | 52.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 327.00 € | ||
| 100mg | 482.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
BGT226 maleate
CAS:1245537-68-1
BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .
Formula:
C28H25F3N6O2·C4H4O4
Purity:
97.75% - 98.78%
Color and Shape:
Solid
Molecular weight:
650.6
Ref: TM-T6072
| 1mg | 60.00 € | ||
| 5mg | 114.00 € | ||
| 10mg | 184.00 € | ||
| 25mg | 404.00 € | ||
| 50mg | 597.00 € | ||
| 100mg | 852.00 € | ||
| 500mg | 1,700.00 € | ||
| 1mL*10mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Friday 3 Jan 2025
GSK2292767
CAS:1254036-66-2
GSK2292767 is a potent and selective PI3Kδ inhibitor.
Formula:
C24H28N6O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
512.58
Ref: TM-T6850
| 1mg | 108.00 € | ||
| 5mg | 469.00 € | ||
| 10mg | 844.00 € | ||
| 25mg | 1,888.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
CNX-1351
CAS:1276105-89-5
CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor.
Formula:
C30H35N7O3S
Purity:
98.83% - 99.69%
Color and Shape:
Solid
Molecular weight:
573.71
Ref: TM-T2256
| 1mg | 48.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 151.00 € | ||
| 25mg | 278.00 € | ||
| 50mg | 513.00 € | ||
| 100mg | 740.00 € | ||
| 500mg | 1,523.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
PI3Kδ-IN-3
CAS:1431540-99-6
PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 …
Formula:
C28H24N6O3
Purity:
98.43%
Color and Shape:
Solid
Molecular weight:
492.53
Ref: TM-T26252
| 1mg | 93.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 291.00 € | ||
| 25mg | 494.00 € | ||
| 50mg | 715.00 € | ||
| 100mg | 1,000.00 € | ||
| 500mg | 1,995.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PI3K-IN-9
CAS:2360875-63-2
PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM).
Formula:
C19H23N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
365.43
Ref: TM-T12458
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
CAL-130
CAS:1431697-74-3
CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).
Formula:
C23H22N8O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
426.47
Ref: TM-T10660
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
APY0201
CAS:1232221-74-7
APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.
Formula:
C23H23N7O
Purity:
98% - 99.21%
Color and Shape:
Solid
Molecular weight:
413.48
Ref: TM-T2061
| 2mg | 77.00 € | ||
| 5mg | 108.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 330.00 € | ||
| 50mg | 560.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PI3Kα-IN-13
CAS:2955529-67-4
PI3Kα-IN-13 (Compound 18a), a PI3Kα inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis …
Formula:
C21H19N5O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
389.41
Ref: TM-T79685
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PI3Kγ inhibitor 7
CAS:2575863-25-9
PI3Kγ Inhibitor 7 (compound 2) is a potent, orally active agent that selectively inhibits PI3Kγ …
Formula:
C31H25N9O2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
555.59
Ref: TM-T79111
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
FD2056
CAS:2685870-87-3
FD2056 is a potent, orally active PI3K inhibitor, with IC50 values of 0.30, 0.80, 1.10, …
Formula:
C23H17ClN6O2S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
476.94
Ref: TM-T79370
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
AZD3458
CAS:2132961-46-5
AZD3458 is a potent and remarkably selective inhibitor of PI3Kγ (PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ …
Formula:
C20H23N3O4S2
Color and Shape:
Solid
Molecular weight:
433.54
Ref: TM-T12466
| 25mg | 900.00 € | ||
| 50mg | 1,180.00 € | ||
| 100mg | 2,050.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
LY117018
CAS:63676-25-5
LY117018 shows antiproliferative effects on breast cancer cell lines. LY117018 is a Raloxifene analog and …
Formula:
C27H25NO4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
459.56
Ref: TM-T15800
| 25mg | 1,410.00 € | ||
| 50mg | 1,845.00 € | ||
| 100mg | 2,329.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
PI3Kdelta inhibitor 1
CAS:2242109-74-4
PI3Kdelta inhibitor 1 is a potent, selective and orally available inhibitor of PI3Kδ with an …
Formula:
C27H38N6O5S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
558.69
Ref: TM-T12461
| 25mg | 1,410.00 € | ||
| 50mg | 1,851.00 € | ||
| 100mg | 2,337.00 € |
Estimated delivery in United States, on Tuesday 4 Feb 2025
