PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
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SAR405
CAS:1523406-39-4
SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor …
Formula:
C19H21ClF3N5O2
Purity:
99.42% - 99.79%
Color and Shape:
Solid
Molecular weight:
443.85
Ref: TM-T12831L
| 1mg | 151.00 € | ||
| 2mg | 219.00 € | ||
| 5mg | 370.00 € | ||
| 10mg | 584.00 € | ||
| 25mg | 888.00 € | ||
| 50mg | 1,607.00 € | ||
| 1mL*10mM (DMSO) | 447.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
PIK-90
CAS:677338-12-4
PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) …
Formula:
C18H17N5O3
Purity:
98.25% - ≥95%
Color and Shape:
Solid
Molecular weight:
351.36
Ref: TM-T2461
| 5mg | 46.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 92.00 € | ||
| 50mg | 142.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
A66
CAS:1166227-08-2
A66 is a specific and effective p110α inhibitor(IC50=32 nM).
Formula:
C17H23N5O2S2
Purity:
99.51% - ≥95%
Color and Shape:
Solid
Molecular weight:
393.53
Ref: TM-T2418
| 2mg | 35.00 € | ||
| 5mg | 50.00 € | ||
| 10mg | 81.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 354.00 € | ||
| 200mg | 497.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Linperlisib
CAS:1702816-75-8
Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3Kδ
Formula:
C28H37FN6O5S
Purity:
99.01%
Color and Shape:
Solid
Molecular weight:
588.69
Ref: TM-T6330
| 1mg | 35.00 € | ||
| 2mg | 47.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 199.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 477.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
CAS:1383716-46-8
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor …
Formula:
C21H25N7O
Purity:
98.60%
Color and Shape:
Solid
Molecular weight:
391.47
Ref: TM-T7944
| 1mg | 66.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 389.00 € | ||
| 50mg | 553.00 € | ||
| 100mg | 735.00 € | ||
| 1mL*10mM (DMSO) | 185.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
CAY10505
CAS:1218777-13-9
CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).
Formula:
C14H8FNO3S
Purity:
99.74% - 99.79%
Color and Shape:
Solid
Molecular weight:
289.28
Ref: TM-T6433
| 10mg | 35.00 € | ||
| 25mg | 56.00 € | ||
| 50mg | 91.00 € | ||
| 100mg | 151.00 € | ||
| 200mg | 212.00 € | ||
| 500mg | 365.00 € | ||
| 1mL*10mM (DMSO) | 40.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
GDC-0326
CAS:1282514-88-8
GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).
Formula:
C19H22N6O3
Purity:
100% - 99.35%
Color and Shape:
Solid
Molecular weight:
382.42
Ref: TM-T3985
| 1mg | 36.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 153.00 € | ||
| 25mg | 252.00 € | ||
| 50mg | 402.00 € | ||
| 100mg | 585.00 € | ||
| 1mL*10mM (DMSO) | 93.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
AZD8186
CAS:1627494-13-6
AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).
Formula:
C24H25F2N3O4
Purity:
99.89% - 99.91%
Color and Shape:
Solid
Molecular weight:
457.47
Ref: TM-T6773
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 98.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 301.00 € | ||
| 100mg | 498.00 € | ||
| 500mg | 1,096.00 € | ||
| 1mL*10mM (DMSO) | 72.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Selective PI3Kδ Inhibitor 1
CAS:2088525-31-7
Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).
Formula:
C23H20FN7O
Purity:
97.96%
Color and Shape:
Solid
Molecular weight:
429.45
Ref: TM-T5831
| 1mg | 57.00 € | ||
| 5mg | 151.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 363.00 € | ||
| 50mg | 495.00 € | ||
| 100mg | 676.00 € | ||
| 200mg | 911.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Pilaralisib analogue
CAS:956958-53-5
Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.
Formula:
C21H16N6O2S2
Purity:
99.30% - 99.72%
Color and Shape:
Solid
Molecular weight:
448.52
Ref: TM-T2377
| 2mg | 38.00 € | ||
| 5mg | 55.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 140.00 € | ||
| 50mg | 217.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 485.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
AZD 6482
CAS:1173900-33-8
AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 …
Formula:
C22H24N4O4
Purity:
99.79% - 99.95%
Color and Shape:
Solid
Molecular weight:
408.45
Ref: TM-T6087
| 1mg | 37.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 119.00 € | ||
| 25mg | 184.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 509.00 € | ||
| 1mL*10mM (DMSO) | 70.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
PIK-293
CAS:900185-01-5
PIK-293 is a PI3K inhibitor, for PI3Kδ( IC50=0.24 μM), and less potent for PI3Kα/β/ γ.
Formula:
C22H19N7O
Purity:
99.8%
Color and Shape:
Solid
Molecular weight:
397.43
Ref: TM-T3348
| 1mg | 48.00 € | ||
| 2mg | 64.00 € | ||
| 5mg | 94.00 € | ||
| 10mg | 149.00 € | ||
| 25mg | 270.00 € | ||
| 50mg | 409.00 € | ||
| 100mg | 590.00 € | ||
| 1mL*10mM (DMSO) | 105.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
ETP-45658
CAS:1198357-79-7
ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 …
Formula:
C16H17N5O2
Purity:
99.13%
Color and Shape:
Solid
Molecular weight:
311.34
Ref: TM-T25399
| 1mg | 52.00 € | ||
| 5mg | 110.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 313.00 € | ||
| 50mg | 505.00 € | ||
| 100mg | 738.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Dactolisib
CAS:915019-65-7
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 …
Formula:
C30H23N5O
Purity:
97.64% - 99.85%
Color and Shape:
Solid
Molecular weight:
469.54
Ref: TM-T2235
| 25mg | 46.00 € | ||
| 50mg | 56.00 € | ||
| 100mg | 69.00 € | ||
| 200mg | 104.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Pectolinarin
CAS:28978-02-1
Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
Formula:
C29H34O15
Purity:
98% - 99.47%
Color and Shape:
Solid
Molecular weight:
622.57
Ref: TM-T2791
| 5mg | 46.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 113.00 € | ||
| 50mg | 175.00 € | ||
| 100mg | 263.00 € | ||
| 1mL*10mM (DMSO) | 68.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
MTX-211
CAS:1952236-05-3
MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and …
Formula:
C20H14Cl2FN5O2S
Purity:
100% - 97.28%
Color and Shape:
Solid
Molecular weight:
478.33
Ref: TM-T4296
| 1mg | 62.00 € | ||
| 5mg | 180.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 450.00 € | ||
| 50mg | 621.00 € | ||
| 100mg | 840.00 € | ||
| 200mg | 1,116.00 € | ||
| 1mL*10mM (DMSO) | 183.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Pictilisib
CAS:957054-30-7
Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K …
Formula:
C23H27N7O3S2
Purity:
99% - 99.97%
Color and Shape:
Solid
Molecular weight:
513.64
Ref: TM-T1994
| 5mg | 45.00 € | ||
| 10mg | 54.00 € | ||
| 50mg | 69.00 € | ||
| 100mg | 96.00 € | ||
| 200mg | 168.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Sincalide
CAS:25126-32-3
Sincalide (CCK-8) is an injectable drug used to diagnose gallbladder and pancreas disorders; it's a …
Formula:
C49H62N10O16S3
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
1143.27
Ref: TM-TP1197
| 1mg | 96.00 € | ||
| 2mg | 128.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 370.00 € | ||
| 25mg | 605.00 € | ||
| 50mg | 852.00 € | ||
| 100mg | 1,149.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
IC-87114
CAS:371242-69-2
IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).
Formula:
C22H19N7O
Purity:
100% - 97.97%
Color and Shape:
Solid
Molecular weight:
397.43
Ref: TM-T2660
| 2mg | 39.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 144.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 373.00 € | ||
| 200mg | 541.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
Orobol
CAS:480-23-9
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.
Formula:
C15H10O6
Purity:
98% - 98%
Color and Shape:
Solid
Molecular weight:
286.24
Ref: TM-TN2019
| 1mg | 178.00 € | ||
| 2mg | 268.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
