mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
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DS-7423
CAS:1222104-37-1
DS-7423: a dual PI3K/mTOR inhibitor; IC50s-PI3Kα: 15.6 nM, mTOR: 34.9 nM, PI3Kβ: 1,143 nM, PI3Kγ: …
Formula:
C22H27F3N10O2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
520.51
Ref: TM-T36083
| 1mg | 124.00 € | ||
| 1ml | 314.00 € | ||
| 5mg | 276.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 692.00 € | ||
| 50mg | 916.00 € | ||
| 100mg | 1,345.00 € |
Estimated delivery in United States, on Friday 18 Oct 2024
Gedatolisib
CAS:1197160-78-3
Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR …
Formula:
C32H41N9O4
Purity:
98% - 99.48%
Color and Shape:
Solid
Molecular weight:
615.73
Ref: TM-T1970
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 223.00 € | ||
| 50mg | 417.00 € | ||
| 100mg | 616.00 € | ||
| 500mg | 1,296.00 € |
Estimated delivery in United States, on Friday 18 Oct 2024
ETP-46464
CAS:1345675-02-6
ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
Formula:
C30H22N4O2
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
470.52
Ref: TM-T2084
| 1ml | 67.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 269.00 € | ||
| 100mg | 430.00 € |
Estimated delivery in United States, on Friday 18 Oct 2024
BGT226 maleate
CAS:1245537-68-1
BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .
Formula:
C28H25F3N6O2·C4H4O4
Purity:
97.75% - 98.78%
Color and Shape:
Solid
Molecular weight:
650.6
Ref: TM-T6072
| 1mg | 58.00 € | ||
| 1ml | 164.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 180.00 € | ||
| 25mg | 396.00 € | ||
| 50mg | 588.00 € | ||
| 100mg | 834.00 € | ||
| 500mg | 1,700.00 € |
Estimated delivery in United States, on Monday 28 Oct 2024
FT-1518
CAS:1313026-58-2
FT-1518 ,exhibits antitumor activity, is a new generation selective, potent and oral bioavailable mTORC1 and …
Formula:
C20H26N8O
Color and Shape:
Solid
Molecular weight:
394.47
Ref: TM-T11328
| 25mg | 560.00 € | ||
| 50mg | 856.00 € | ||
| 100mg | 1,530.00 € |
Estimated delivery in United States, on Friday 29 Nov 2024
mTOR inhibitor-2
CAS:2219323-96-1
mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).
Formula:
C23H21N7O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
411.46
Ref: TM-T12124
| 25mg | 1,549.00 € | ||
| 50mg | 2,038.00 € | ||
| 100mg | 2,617.00 € |
Estimated delivery in United States, on Friday 29 Nov 2024
P-2281
CAS:1112994-35-0
P-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced …
Formula:
C9H8ClN3O
Purity:
99.95%
Color and Shape:
Solid
Molecular weight:
209.63
Ref: TM-T28285
| 1mg | 152.00 € | ||
| 5mg | 368.00 € | ||
| 10mg | 528.00 € | ||
| 25mg | 907.00 € | ||
| 50mg | 1,197.00 € | ||
| 100mg | 1,642.00 € |
Estimated delivery in United States, on Friday 29 Nov 2024
PI3K/mTOR Inhibitor-2
CAS:1848242-58-9
Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ & mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor …
Formula:
C20H13ClF2N4O4S
Purity:
96.16%
Color and Shape:
Solid
Molecular weight:
478.86
Ref: TM-T12459
| 1mg | 56.00 € | ||
| 1ml | 147.00 € | ||
| 5mg | 141.00 € | ||
| 10mg | 218.00 € | ||
| 25mg | 364.00 € | ||
| 50mg | 520.00 € | ||
| 100mg | 703.00 € | ||
| 200mg | 903.00 € |
Estimated delivery in United States, on Friday 29 Nov 2024
JR-AB2-011
CAS:2411853-34-2
JR-AB2-011: selective mTORC2 inhibitor, IC50 = 0.36μM, blocks Rictor-mTOR, Ki = 0.19μM, cytotoxic in glioblastoma.
Formula:
C17H14Cl2FN3OS
Purity:
98.87%
Color and Shape:
Solid
Molecular weight:
398.28
Ref: TM-T11728
| 1mg | 94.00 € | ||
| 1ml | 222.00 € | ||
| 5mg | 199.00 € | ||
| 10mg | 337.00 € | ||
| 25mg | 616.00 € | ||
| 50mg | 924.00 € | ||
| 100mg | 1,234.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
WAY-600
CAS:1062159-35-6
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; …
Formula:
C28H30N8O
Purity:
99.63%
Color and Shape:
Solid
Molecular weight:
494.59
Ref: TM-T6730
| 1mg | 38.00 € | ||
| 1ml | 111.00 € | ||
| 2mg | 63.00 € | ||
| 5mg | 95.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 240.00 € | ||
| 50mg | 355.00 € | ||
| 100mg | 495.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
mTOR inhibitor 9b
CAS:1144075-34-2
mTOR inhibitor 9b is an enzyme inhibitor of protein kinase mTOR he phosphatidylinositol 3-kinase PIK3CA …
Formula:
C21H23N5O2S
Purity:
99.53%
Color and Shape:
Soild
Molecular weight:
409.5
Ref: TM-T67703
| 1mg | 327.00 € | ||
| 5mg | 774.00 € | ||
| 10mg | 1,054.00 € | ||
| 25mg | 1,483.00 € | ||
| 50mg | 1,850.00 € | ||
| 100mg | 2,320.00 € | ||
| 500mg | 4,568.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Rheb inhibitor NR1
CAS:2216763-38-9
Rheb inhibitor NR1 is a Rheb inhibitor and selective mTORC1 inhibitor that promotes phosphorylation of …
Formula:
C25H19BrCl2N2O3S
Purity:
99.72%
Color and Shape:
Solid
Molecular weight:
578.3
Ref: TM-T16741
| 1mg | 91.00 € | ||
| 1ml | 46.00 € | ||
| 5mg | 190.00 € | ||
| 10mg | 307.00 € | ||
| 25mg | 618.00 € | ||
| 50mg | 932.00 € | ||
| 100mg | 1,568.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
mTOR inhibitor-3
CAS:1207358-59-5
mTOR inhibitor-3 is a selective mTOR inhibitor (Ki= 1.5 nM). mTOR inhibitor-3 inhibits mTORC1 and …
Formula:
C25H30N8O2
Purity:
98.29% - 99%
Color and Shape:
Solid
Molecular weight:
474.56
Ref: TM-T12123
| 1mg | 59.00 € | ||
| 1ml | 132.00 € | ||
| 5mg | 124.00 € | ||
| 10mg | 176.00 € | ||
| 25mg | 300.00 € | ||
| 50mg | 453.00 € | ||
| 100mg | 640.00 € | ||
| 500mg | 1,327.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
WYE-132
CAS:1144068-46-1
WYE-125132: potent mTOR inhibitor, IC50 0.19 nM, selective over PI3Ks/hSMG1/ATR.
Formula:
C27H33N7O4
Purity:
99.16%
Color and Shape:
Solid
Molecular weight:
519.6
Ref: TM-T6346
| 1mg | 46.00 € | ||
| 1ml | 96.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 275.00 € | ||
| 100mg | 406.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
GNE-490
CAS:1033739-92-2
GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 …
Formula:
C18H22N6O2S
Purity:
96.74%
Color and Shape:
Solid
Molecular weight:
386.47
Ref: TM-T22339
| 1mg | 82.00 € | ||
| 1ml | 197.00 € | ||
| 2mg | 111.00 € | ||
| 5mg | 182.00 € | ||
| 10mg | 310.00 € | ||
| 25mg | 490.00 € | ||
| 50mg | 676.00 € | ||
| 100mg | 897.00 € | ||
| 200mg | 1,235.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
mTOR inhibitor-11
CAS:3033409-32-1
mTOR inhibitor-11 (Compound 9) is a brain-penetrant compound capable of inhibiting mTOR with an IC50 …
Formula:
C21H26N6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
394.47
Ref: TM-T79211
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
MTI-31
CAS:1567915-38-1
MTI-31 (LXI-15029) is a potent oral mTORC1/2 inhibitor with a Kd of 0.20 nM, >5,000-fold …
Formula:
C26H30N6O3
Purity:
99.76%
Color and Shape:
Solid
Molecular weight:
474.55
Ref: TM-T35343
| 1mg | 183.00 € | ||
| 5mg | 423.00 € | ||
| 10mg | 645.00 € | ||
| 25mg | 1,012.00 € | ||
| 50mg | 1,447.00 € | ||
| 100mg | 2,023.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
CC214-1
CAS:1021920-32-0
CC214-1 is an mTOR inhibitor that inhibits protein translation, induces autophagy, and is an in …
Formula:
C20H21N7O2
Purity:
97.87%
Color and Shape:
Solid
Molecular weight:
391.43
Ref: TM-T9314
| 1mg | 181.00 € | ||
| 5mg | 447.00 € | ||
| 10mg | 640.00 € | ||
| 25mg | 998.00 € | ||
| 50mg | 1,377.00 € | ||
| 100mg | 1,821.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
PF-04979064
CAS:1220699-06-8
PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM …
Formula:
C24H26N6O3
Purity:
98.04% - ≥98%
Color and Shape:
Solid
Molecular weight:
446.5
Ref: TM-T7343
| 1ml | 63.00 € | ||
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 255.00 € |
Estimated delivery in United States, on Friday 27 Dec 2024
GDC-0349
CAS:1207360-89-1
GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR, 790-fold inhibitory effect against …
Formula:
C24H32N6O3
Purity:
96.00% - 98.98%
Color and Shape:
Solid
Molecular weight:
452.55
Ref: TM-T6510
| 1ml | 70.00 € | ||
| 2mg | 39.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 105.00 € | ||
| 25mg | 210.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 453.00 € | ||
| 500mg | To inquire |
Estimated delivery in United States, on Friday 27 Dec 2024
