mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Read more
Hederacolchiside A1
CAS:106577-39-3
Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via …
Formula:
C47H76O16
Purity:
99.54% - 99.92%
Color and Shape:
Solid
Molecular weight:
897.1
Ref: TM-T2P2806
| 1mg | 47.00 € | ||
| 5mg | 119.00 € | ||
| 10mg | 172.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 606.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Arnicolide D
CAS:34532-68-8
Arnicolide D is a sesquiterpene lactone.
Formula:
C19H24O5
Purity:
96.66%
Color and Shape:
Solid
Molecular weight:
332.39
Ref: TM-TN1405
| 1mg | 149.00 € | ||
| 5mg | 441.00 € | ||
| 10mg | 635.00 € | ||
| 25mg | 917.00 € | ||
| 50mg | 1,290.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Torkinib
CAS:1092351-67-1
Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). …
Formula:
C16H16N6O
Purity:
99.23%
Color and Shape:
Solid
Molecular weight:
308.34
Ref: TM-T2414
| 5mg | 56.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 133.00 € | ||
| 100mg | 223.00 € | ||
| 200mg | 331.00 € | ||
| 500mg | 550.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Temsirolimus
CAS:162635-04-3
Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment …
Formula:
C56H87NO16
Purity:
100% - 99.64%
Color and Shape:
White Crystalline Powder
Molecular weight:
1030.29
Ref: TM-T2145
| 2mg | 45.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 91.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 472.00 € | ||
| 500mg | 1,049.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Rotundic acid
CAS:20137-37-5
Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.
Formula:
C30H48O5
Purity:
96.91% - 99.28%
Color and Shape:
Solid
Molecular weight:
488.7
Ref: TM-T5S0506
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 141.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 330.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TMBIM6 antagonist-1
CAS:123134-61-2
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor
Formula:
C15H12N2O3
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
268.27
Ref: TM-T8649
| 1mg | 92.00 € | ||
| 2mg | 119.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 312.00 € | ||
| 25mg | 560.00 € | ||
| 50mg | 799.00 € | ||
| 100mg | 1,098.00 € | ||
| 500mg | 2,183.00 € | ||
| 1mL*10mM (DMSO) | 199.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Zotarolimus
CAS:221877-54-9
Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
Formula:
C52H79N5O12
Purity:
95% - ≥98%
Color and Shape:
Solid
Molecular weight:
966.21
Ref: TM-T6033
| 1mg | 65.00 € | ||
| 2mg | 95.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 385.00 € | ||
| 50mg | 555.00 € | ||
| 100mg | 800.00 € | ||
| 1mL*10mM (DMSO) | 237.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
CC-115
CAS:1228013-15-7
CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
Formula:
C16H16N8O
Purity:
86.79% - 99.22%
Color and Shape:
Solid
Molecular weight:
336.35
Ref: TM-T3541
| 2mg | 45.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 175.00 € | ||
| 50mg | 294.00 € | ||
| 100mg | 461.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Torin 2
CAS:1223001-51-1
Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for …
Formula:
C24H15F3N4O
Purity:
98.31% - 99.32%
Color and Shape:
Solid
Molecular weight:
432.4
Ref: TM-T6100
| 2mg | 41.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 90.00 € | ||
| 25mg | 163.00 € | ||
| 50mg | 252.00 € | ||
| 100mg | 375.00 € | ||
| 200mg | 557.00 € | ||
| 500mg | 885.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Lupiwighteone
CAS:104691-86-3
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.
Formula:
C20H18O5
Purity:
99.20%
Color and Shape:
Solid
Molecular weight:
338.35
Ref: TM-TN1891
| 1mg | 153.00 € | ||
| 5mg | 369.00 € | ||
| 10mg | 547.00 € | ||
| 25mg | 877.00 € | ||
| 50mg | 1,188.00 € | ||
| 1mL*10mM (DMSO) | 538.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PI-103
CAS:371935-74-9
PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for …
Formula:
C19H16N4O3
Purity:
96.59% - 99.3%
Color and Shape:
Solid
Molecular weight:
348.36
Ref: TM-T6143
| 5mg | 58.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 125.00 € | ||
| 50mg | 197.00 € | ||
| 100mg | 363.00 € | ||
| 200mg | 553.00 € | ||
| 1mL*10mM (DMSO) | 60.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
WYE-354
CAS:1062169-56-5
WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and …
Formula:
C24H29N7O5
Purity:
98.31% - 99.61%
Color and Shape:
Solid
Molecular weight:
495.53
Ref: TM-T6731
| 5mg | 50.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 152.00 € | ||
| 50mg | 275.00 € | ||
| 100mg | 356.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Bimiralisib
CAS:1225037-39-7
Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, …
Formula:
C17H20F3N7O2
Purity:
97.58% - 99.88%
Color and Shape:
Solid
Molecular weight:
411.38
Ref: TM-T2265
| 1mg | 35.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 216.00 € | ||
| 50mg | 346.00 € | ||
| 100mg | 530.00 € | ||
| 1mL*10mM (DMSO) | 85.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Omipalisib
CAS:1086062-66-9
Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.
Formula:
C25H17F2N5O3S
Purity:
98% - 99.8%
Color and Shape:
Solid
Molecular weight:
505.5
Ref: TM-T1861
| 5mg | 62.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 272.00 € | ||
| 100mg | 417.00 € | ||
| 1mL*10mM (DMSO) | 69.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BGT226
CAS:915020-55-2
BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ …
Formula:
C28H25F3N6O2
Purity:
100% - 98.40%
Color and Shape:
Solid
Molecular weight:
534.53
Ref: TM-T6072L
| 1mg | 52.00 € | ||
| 5mg | 112.00 € | ||
| 10mg | 183.00 € | ||
| 25mg | 404.00 € | ||
| 50mg | 592.00 € | ||
| 100mg | 834.00 € | ||
| 1mL*10mM (DMSO) | 155.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
XL388
CAS:1251156-08-7
XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 nM), 1000-fold …
Formula:
C23H22FN3O4S
Purity:
99.39% - 99.53%
Color and Shape:
Solid
Molecular weight:
455.5
Ref: TM-T6030
| 1mg | 45.00 € | ||
| 2mg | 57.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 139.00 € | ||
| 25mg | 276.00 € | ||
| 50mg | 456.00 € | ||
| 100mg | 669.00 € | ||
| 1mL*10mM (DMSO) | 107.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GNE-493
CAS:1033735-94-2
GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s …
Formula:
C17H20N6O2S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
372.44
Ref: TM-T7166
| 1mg | 49.00 € | ||
| 5mg | 102.00 € | ||
| 10mg | 165.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 537.00 € | ||
| 100mg | 827.00 € | ||
| 1mL*10mM (DMSO) | 115.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Cyclovirobuxine D
CAS:860-79-7
Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.
Formula:
C26H46N2O
Purity:
97.78% - 98%
Color and Shape:
Solid
Molecular weight:
402.66
Ref: TM-T2974
| 20mg | 54.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
OSI-027
CAS:936890-98-1
OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 …
Formula:
C21H22N6O3
Purity:
≥95%
Color and Shape:
Solid
Molecular weight:
406.44
Ref: TM-T6319
| 1mg | 41.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 244.00 € | ||
| 50mg | 383.00 € | ||
| 100mg | 557.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PF-04691502
CAS:1013101-36-4
PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.
Formula:
C22H27N5O4
Purity:
96.27% - ≥95%
Color and Shape:
Solid
Molecular weight:
425.48
Ref: TM-T6251
| 1mg | 36.00 € | ||
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 92.00 € | ||
| 25mg | 123.00 € | ||
| 50mg | 195.00 € | ||
| 100mg | 347.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
