mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
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Mito-LND
CAS:2361564-49-8
Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
Formula:
C43H45BrCl2N3OP
Purity:
97.25% - 98.34%
Color and Shape:
Solid
Molecular weight:
801.62
Ref: TM-T9211
| 1mg | 131.00 € | ||
| 2mg | 180.00 € | ||
| 5mg | 271.00 € | ||
| 10mg | 449.00 € | ||
| 25mg | 740.00 € | ||
| 50mg | 1,013.00 € | ||
| 100mg | 1,388.00 € | ||
| 1mL*10mM (DMSO) | 397.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GNE-317
CAS:1394076-92-6
GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).
Formula:
C19H22N6O3S
Purity:
99.08% - 99.42%
Color and Shape:
Solid
Molecular weight:
414.48
Ref: TM-T6845
| 1mg | 39.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 82.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | 207.00 € | ||
| 50mg | 342.00 € | ||
| 100mg | 426.00 € | ||
| 200mg | 623.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Everolimus
CAS:159351-69-6
Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone …
Formula:
C53H83NO14
Purity:
97.76% - 99.52%
Color and Shape:
Off-White To Light Yellow Powd
Molecular weight:
958.22
Ref: TM-T1784
| 5mg | 43.00 € | ||
| 10mg | 54.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 94.00 € | ||
| 100mg | 119.00 € | ||
| 200mg | 174.00 € | ||
| 500mg | 291.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
25(R,S)-Ruscogenin
CAS:874485-32-2
25(R,S)-Ruscogenin is able to regulate the PI3K/Akt/mTOR signalling pathway, and hinder the metastasis of hepatocellular …
Formula:
C27H42O4
Purity:
99.32% - 99.89%
Color and Shape:
Solid
Molecular weight:
430.62
Ref: TM-T5740
| 1mg | 52.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 138.00 € | ||
| 25mg | 222.00 € | ||
| 50mg | 327.00 € | ||
| 100mg | 482.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
AZD-8055
CAS:1009298-09-2
AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold …
Formula:
C25H31N5O4
Purity:
97.45% - 99.69%
Color and Shape:
Solid
Molecular weight:
465.54
Ref: TM-T1859
| 5mg | 42.00 € | ||
| 10mg | 56.00 € | ||
| 25mg | 81.00 € | ||
| 50mg | 90.00 € | ||
| 100mg | 146.00 € | ||
| 200mg | 262.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Palomid 529
CAS:914913-88-5
Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular …
Formula:
C24H22O6
Purity:
98.59% - 99.03%
Color and Shape:
Solid
Molecular weight:
406.43
Ref: TM-T2706
| 5mg | 47.00 € | ||
| 10mg | 69.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 184.00 € | ||
| 100mg | 276.00 € | ||
| 1mL*10mM (DMSO) | 52.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
KU-0063794
CAS:938440-64-3
KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.
Formula:
C25H31N5O4
Purity:
100% - 98.35%
Color and Shape:
Solid
Molecular weight:
465.54
Ref: TM-T2475
| 5mg | 61.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 127.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 407.00 € | ||
| 500mg | 918.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
SC99
CAS:882290-02-0
SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.
Formula:
C15H8Cl2FN3O
Purity:
99.56%
Color and Shape:
Solid
Molecular weight:
336.15
Ref: TM-T8719
| 1mg | 44.00 € | ||
| 5mg | 90.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 232.00 € | ||
| 50mg | 350.00 € | ||
| 100mg | 436.00 € | ||
| 200mg | 608.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
L-Leucine
CAS:61-90-5
L-Leucine is an essential amino acid vital for protein synthesis, metabolism, muscle and bone repair, …
Formula:
C6H13NO2
Purity:
100%
Color and Shape:
White Solid Crystalline
Molecular weight:
131.17
Ref: TM-T3O2749
| 100mg | 49.00 € | ||
| 250mg | 89.00 € | ||
| 500mg | 127.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Vistusertib
CAS:1009298-59-2
Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with …
Formula:
C25H30N6O3
Purity:
97.94% - 98.29%
Color and Shape:
Solid
Molecular weight:
462.54
Ref: TM-T1961
| 2mg | 50.00 € | ||
| 5mg | 73.00 € | ||
| 10mg | 115.00 € | ||
| 25mg | 172.00 € | ||
| 50mg | 233.00 € | ||
| 100mg | 369.00 € | ||
| 1mL*10mM (DMSO) | 83.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Onatasertib
CAS:1228013-30-6
Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.
Formula:
C21H27N5O3
Purity:
99.14% - 99.91%
Color and Shape:
Solid
Molecular weight:
397.47
Ref: TM-T3351
| 1mg | 41.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 231.00 € | ||
| 50mg | 384.00 € | ||
| 100mg | 549.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Voxtalisib
CAS:934493-76-2
Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 …
Formula:
C13H14N6O
Purity:
98.01% - 99.36%
Color and Shape:
Solid
Molecular weight:
270.29
Ref: TM-T7014
| 1mg | 38.00 € | ||
| 2mg | 49.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 237.00 € | ||
| 50mg | 380.00 € | ||
| 100mg | 552.00 € | ||
| 1mL*10mM (DMSO) | 78.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
PP121
CAS:1092788-83-4
PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from …
Formula:
C17H17N7
Purity:
99.19% - 99.67%
Color and Shape:
Solid
Molecular weight:
319.36
Ref: TM-T2415
| 5mg | 60.00 € | ||
| 10mg | 89.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 237.00 € | ||
| 100mg | 344.00 € | ||
| 1mL*10mM (DMSO) | 56.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Polyphyllin I
CAS:50773-41-6
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression …
Formula:
C44H70O16
Purity:
98% - 99.5%
Color and Shape:
Solid
Molecular weight:
855.02
Ref: TM-T3895
| 5mg | 56.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 147.00 € | ||
| 50mg | 222.00 € | ||
| 100mg | 369.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Torin 1
CAS:1222998-36-8
Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold …
Formula:
C35H28F3N5O2
Purity:
98.3% - 99.38%
Color and Shape:
Solid
Molecular weight:
607.62
Ref: TM-T6045
| 1mg | 36.00 € | ||
| 2mg | 48.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 170.00 € | ||
| 50mg | 305.00 € | ||
| 100mg | 471.00 € | ||
| 500mg | 1,015.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
G5-7
CAS:939681-36-4
G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.
Formula:
C22H19F2NO3
Purity:
97.30%
Color and Shape:
Solid
Molecular weight:
383.39
Ref: TM-T8742
| 1mg | 49.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 250.00 € | ||
| 50mg | 360.00 € | ||
| 100mg | 505.00 € | ||
| 200mg | 685.00 € | ||
| 1mL*10mM (DMSO) | 102.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Apitolisib
CAS:1032754-93-0
Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, …
Formula:
C23H30N8O3S
Purity:
98.28% - 99.52%
Color and Shape:
Solid
Molecular weight:
498.6
Ref: TM-T1916
| 2mg | 45.00 € | ||
| 5mg | 63.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 155.00 € | ||
| 50mg | 242.00 € | ||
| 100mg | 397.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Daphnetin
CAS:486-35-1
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR …
Formula:
C9H6O4
Purity:
98.33% - 99.82%
Color and Shape:
Solid
Molecular weight:
178.14
Ref: TM-T2851
| 10mg | 50.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 164.00 € | ||
| 100mg | 239.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
GSK1059615
CAS:958852-01-2
GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, …
Formula:
C18H11N3O2S
Purity:
≥95% - ≥95%
Color and Shape:
Solid
Molecular weight:
333.36
Ref: TM-T2357
| 2mg | 45.00 € | ||
| 5mg | 66.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 191.00 € | ||
| 50mg | 347.00 € | ||
| 100mg | 498.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Sapanisertib
CAS:1224844-38-5
Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.
Formula:
C15H15N7O
Purity:
100% - 99.34%
Color and Shape:
Solid
Molecular weight:
309.33
Ref: TM-T1838
| 1mg | 40.00 € | ||
| 2mg | 51.00 € | ||
| 5mg | 83.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 157.00 € | ||
| 50mg | 231.00 € | ||
| 100mg | 344.00 € | ||
| 500mg | 824.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
