Organic Building Blocks

2-(Benzyloxy)-5-nitrobenzoic acid

Applications Oleyl Oleate is a synthetic analog of jojoba oil. Used as a wax ester for various applications.
References Lopes, D. et al.: Food Sci. Biotech., 20, 1203 (2011); Radzi, S. et al.: J. Oleo. Sci., 59, 127 (2010);

Applications Arecoline has shown regulatory properties of controlling plasminogen activator inhibitor-1 expression in human buccal mucosa fibroblasts.
References Tsai, C.H., et al.: J. Oral. Pathol. Med., 44, 669 (2015);

Applications Mono and dibasic phosphate esters are anionic surfactants which have the main feature of the stability in alkaline conditions over other surfactants. They have a wide range of properties including outstanding wetting, emulsification, lubrication, coupling activity and detergency.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ramirez, F., et al.: Tetrahedron, 35, 1581 (1979);

Applications 3-(Diethylamino)-7-[2-[4-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]methylamino]phenyl]diazenyl]-5-phenylphenazinium is used in preparation of Peptide derivatives as imaging probes of Cathepsin catalytic activity.
References Kindermann, M., et al.: PCT Int. Appl., (2018);

Applications 3-Methyl-2(5H)-furanone (cas# 22122-36-7) is a useful research chemical.

Applications N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxybutanediamide, is a bifunctional chelator.

Applications Chromone-3-carboxylic Acid (cas# 39079-62-4) is a useful research chemical.

Stability Light Sensitive
Applications Used in the manufacturing plastics; synthetic rubber; resins; insulator.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meyer. H.J., et al.: Arzneim.-Forsch., 19, 617 (1969), Pahwa, R., et al.: Vet. Hum. Toxicol., 35, 516 (1993),

Applications α-Cyclohexyl-benzeneacetic Acid is a useful synthetic intermediate. It was used as one of the reactants to prepare phenylureidobenzazepinones as cholecystokinin-B receptor antagonists. It can also be used to synthesize benzimidazole derivatives as potent AMP-activated protein kinase activators.
References Lowe, J., et al.: J. Med. Chem., 37, 3789 (1994); Charton, J., et al.: Bioorg. Med. Chem., 14, 4490 (2006)

Applications Sodium Acrylate is the acid form of Acrylic Acid (A191350); which is an antibacterial agent.
References Kind, T., et al.: Anal. Biochem., 363, 185 (2007), Spratlin, J., et al.: Clin. Cancer Res., 15, 431 (2009),

Stability Hygroscopic
Applications 2-Hydroxy-5-Amino-N-(2-carboxy-4-aminophenyl)benzoic Acid is an impurity from the synthesis of Mesalamine (M258100).
References Friedman, G., et al.: Am. J. Gastroenterol., 81, 141 (1986); Tursi A., Expert Opin. Pharmacother., 6, 69 (2005);

Applications 1,​6,​13,​18-​Tetraoxacyclotetraco​sane-​7,​12,​19,​24-​tetrone can be used in degradation process investigation of thermoplastic polyurethane elastomer in supercritical methanol.
References Liu, L., et al.: Polym Degrad Stabil, 98, 2520 (2013)

Applications (4-Vinylphenyl)methanol (cas# 1074-61-9) is a useful research chemical.

Applications Polyquaternium 11 is found to suppress melanin elution in shampoo thus may prevent hair from dulling after repeated shampoo use.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hagihara, M.: Frag. J., 40, 23 (2012)

Stability Hygroscopic
Applications D-Arabinose is a pharmaceutical intermediate and a food addictive. A reducing sugar and pentose analog of D-ribose.
References Chen, X., et al.: Int. J. Biol. Macromol., 104, 1294 (2017); Konuchova, M., et al.: Chemicke Listy, 110, 491 (2016); Pelckmans, M., et al.: ACS Catalysis, 8, 4201 (2018); Haghparast, S., et al.: J. Agric. Sci. Techn., 15, 87 (2013)

Applications Mandelonitrile along side hydroxynitrile lyase is used to induced cyanogenesis in seeds.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Halter, Jonas G., et al.: J. of Materials Chem., 2(3), 853-858 (2014)

Applications A fodder additive for poultry used to prevent coccidiosis infections. Antiprotozoan drug.
References Morrison, W.D. et al.: Poult. Sci., 46, 391 (1967); Davis, J.L. et al.: Vet. Pharmacol. Therap., 9, 1145 (2009);

Applications An metabolite of Cotinine. In equilibrium with 5’-Hydroxycotinine the cyclized form.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Morselli, P.L, et al.: J. Med. Chem., 10, 1033 (1967); Murphy, S.E. et. al.: Chem. Res. Toxicol. 12, 639 (1999)

Applications 4-tert-Butyl-d9-phenol-2,3,5,6-d4 is the labelled analogue of 4-tert-Butylphenol (B694105), a reactant in the preparation of (2-bromocyclopent-2-en-1-yl)phenols.

Applications 4,6-Di(methyl-d3)benzen-2,3,5-d3-amine is a useful isotopically labeled research compound.

Applications N6-​[Bis(ethylamino)​methylene]​-D-​lysine is an intermediate in preparation of analogs of transforming and epidermal growth factor fragment.
References Nestor, John J., et al.: U.S., (1987);

Stability Volatile
Applications Labelled Methylene Chloride used in organic chemical reactions as a general solvent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fulmer, G. et al.: Organometal., 29, 2176 (2010); Kobayashi, M. et al.: J. Porph. Pthalo., 16, 359 (2012);

Applications 2-Ethyl-3,6-dimethylpyrazine is a flavour-active and non-volatile compound identified in thermally treated yeast extracts. It is also useful in the synthesis of new flavour additive species of pyrazines.
References Alim, A., et al.: J. Sci. Food Agric., 98, 3774 (2018); Lai, M., et al.: J. Therm. Anal. Calorim., 128, 1627 (2017)

Applications Triglyme could be a useful component for absorption refrigeration based on better environmental, health, and safety properties.
References Papadopoulos, A. I., et al.: Energy Convers. Manag., 223, 113262 (2020)

Applications Dowex® 1X4 Chloride Form is an adsorbent material, strongly basic (type I) anion exchange resin used in pharmaceuticals.

Stability Moisture Sensitive
Applications A phosphorylating agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sartori: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)

Applications Bathocuproine Disulfonic Acid Disodium salt is a mixture of isomers suitable for determination of copper. It can also be used in analytical role and study on analytical conditions of antioxidant assays for biological samples based on reduction of copper complexes.
References Marques, S. S., et al.: Int J Mol Sci, 15, 11387 (2014)

Applications Vitamin K3 (V676130) derivative. Menaquinol analog. Induces mutations in Escherichia coli nitrate reductase A.
References Zhao, Z. et al., Biochem., 42, 14225 (2003); Zhao, Z. et al., Biochem., 42, 5403 (2003)

Applications One of the alkyl ethers with tert-Bu groups in their molecules which showed very poor biodegradability, tert-Bu Me ether (MTBE)  [1634-04-4] had no effect on the biodegradability of gasoline blended with it. Studies on the biodegradation of several alkyl ethers were carried out by measuring the O uptake rate in the presence of standard activated sludge as a source of microorganisms.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Siegemund, B., et al.: Acute Toxicity Data, 1, 200 (1992),

Applications Occurs in coal tar. Is formed during distillation of coal, in very small amount during distillation or pyrolysis of many fats and oils. Chrysene is one of the basic polycyclic aromatic hydrocarbon (PAH) which is toxic environmental pollutant and consistently exposed to sunlight. However, little information is available on its photogenotoxicity.  The objective of the present study was to analyze the effects of Chrysene, under environmental intensity of UVB (0.6 mW/cm2) in human skin epidermal cell line (HaCaT).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anderson, D., et al.: Mutat. Res., 307, 261 (1994), Diamond, S., et al.: Environ. Toxicol. Chem., 25, 3015 (2006), Fotakis, G., et al.: Toxicol. Lett., 160, 171 (2006),

Applications 1,1-Bis(4-hydroxyphenyl)-2-phenyl-1-butene (cas# 91221-46-4) is a compound useful in organic synthesis.

Applications (E)-Ethyl 4-Bromo-3-methyl-2-butenoate (cas# 51318-62-8) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride (cas# 637-01-4) is a useful compound for membrane-tethering cytochrome c to study its impact on cell death in yeast.
References Toth, A., et al.: Cell Death Dis., 11, 722 (2020)

Applications 17a-Oxa-D-homo-5β-androst-1-ene-3,17-dione is a metabolite in the urine of men following treatment with Δ1-testololactone, which is an idiopathic oligospermic infertility. Also, it is derived from Androstenedione (A637550), which is a testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic steroid).
References Yaeger, R. L., et al.: Drug Metab. Dispos., 13, 107-109 (1985); Walker, V.R., et al.: Anal. Biopchem., 234, 194 (1996), King, D.S., et al.: J. Am. Med. Assoc., 281, 2020 (1999)

Stability Hygroscopic
Applications 2,4,5-Trimethylaniline (T797580(P)) is the free base of 2,4,5-Trimethylaniline Hydrochloride. 2,4,5-Trimethylaniline is a carcinogenic aromatic amine used in the leather and textile industry.
References Kawakami, Tsuyoshi, et al.: Kankyo Kagaku, 22(4), 197-204 (2012); Chen, Xiaomei, et al.: Fenxi Ceshi Xuebao, 17(4), 50-53 (1998);

Applications Azosemide is a high-ceiling diuretic agent. It is used in the treatment of edematous states and hypertension.
References Ogawa, K., et al.: Inter. J. Clin. Pharm. Ther. Toxicol., 22, 401 (1984); Suh, O., et al.: Biopharm. Drug Disposition., 24, 275 (2003)

Applications 3,4-Dihydro-2H-benzo[b][1,4]oxazin-6-ol (cas# 26021-57-8) is a useful research chemical.

Applications 5-Chloronaphthalene-1-sulfonyl Chloride (cas# 6291-07-2) is a compound useful in organic synthesis.

Applications NN'-Bis(2-hydroxyethyl)urea (cas# 15438-70-7) is a useful research chemical.

Applications (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide is a part of the synthetic preparation of the synthesis and inhibitory effect on ADP-induced platelet aggregation of ticagrelor derivatives as antiplatelets agents.
References Zhang, H., et al.: Bioorganic Med. Chem. Lett., 22, 3598 (2012).

Applications Bis(2-butoxyethyl) 2-Hydroxyethyl Phosphate Triester is a metabolite of Tris(2-butyloxyethyl)phosphate (T875030), which is an organophosphate, that can be used in the preparation of flame retardant, such as viscose fiber.
References Wang, Y., et al.: Fangzhi Xuebao, 33, 16 (2012); Xiaoshan, L. et al.: Aquatic Toxicology, 114, 173 (2012);

Stability Light Sensitive
Applications Acrylamide (1-13c, 99%) (cas# 287399-24-0) is a useful research chemical.

Applications L-AP3 is a selective antagonist of the PI-linked metabotropic glutamate response.

Stability Very Hygroscopic
Applications Accumulation and excretion of 2-Hydroxyhexanedioic Acid (with 2-ketoadipic and 2-aminoadipic) in urine can be caused by 2-ketoadipic acidemia, probably without adverse phenotypic effects , due to deficiency of 2-ketoadipic dehydrogenase.
References Svendsen, J., et al.: J. Chromatogr., 337, 9 (1985); Przyrembel, H., et al.: Clin. Chim. Acta 58, 257 (1975).

Stability Hygroscopic
Applications N'-Formylkynurenine is a photooxidation product of Tryptophan (T947200), and is also used as a photosensitizer of near-ultraviolet radiation by generating singlet oxygen and superoxide.
References Grossweiner, L.: Curr. Eye Res., 3, 137 (1984); Møller, I. & Kristensen, B.: Free Radical Bio. Med., 40, 430 (2006); Pileni, M., et al.: J. Phys. Chem., 80, 1804 (1976)

Applications Ferulic Acid Methyl Ester is a derivative of Ferulic Acid (F308900), used as an antioxidant and food preservative. It has less antioxidant capacity than ferulic acid.
References Smart, M.G., et al.: Aust. J. Plant Physiol., 6, 485 (1979), Chen, C., et al.: J. Food Lipids, 2, 35,1995, Benzie, I., et al.: Anal. Biochem. 239, 70 (1996), Nardini, M., et al.: Food Chem., 79, 119 (2002), Lee, J., et al.: J. Agric. Food Chem., 52, 2647 (2004),

Impurity Terbinafine BP Impurity A; Terbinafine USP Related Compound A
Applications N-Methyl-1-naphthalenemethanamine hydrochloride (Terbinafine BP Impurity A; Terbinafine USP Related Compound A) is an intermediate used in the synthesis of various pharmaceuticals such as Terbinafine hydrochloride (T107500) and Butenafine hydrochloride (B690195).
References Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999); Kokjohn, K., et al.: Int. J. Dermatol., 42, 11 (2003); Sumikawa, M., et al.: J. Dermatol., 34, 456 (2007)

Impurity Metoprolol EP Impurity G
Applications Tyrosol (Metoprolol EP Impurity G) is a phenolic antioxidant.
References Perez-Trujillo, M., et al.: J. Agric. Food Chem., 58, 9129 (2010), Gregus, P., et al.: J. Pharm. Biomed. Anal., 53, 674 (2010),

Applications CJC 1295 is used in application of growth hormone releasing hormone agonist to preparing anti-aging agent.
References Sally, A. V., et al.: Faming Zhuanli Shenqing, (2020);

Stability Hygroscopic
Applications Betahistine Methanesulfonate (cas# 54856-23-4) is a useful research chemical.

Applications 4-Methoxyaniline hydrochloride (cas# 20265-97-8) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 5-acetyloxolan-2-one (cas# 29393-32-6) is a useful research chemical.

Applications Dialkyl Phthalate (Alkyl=heptyl, nonyl, undecyl) can be used as a plasticizer.
References Zhou, Q., et al.: Faming Zhuanli Shenqing, CN 104650520 A, 20150527 (2015); Mao, J., et al.: Faming Zhuanli Shenqing, CN 104694065 A, 2015010 (2015).

Applications Mineral Oil can be used as preferred lubricant for aerosol lubricant and dispensing method. An aerosol container containing a propellant and a highly hydrogenated mineral oil lubricant for the lubrication of gaskets in pipe segments.
References Green, R., et al.: U.S., US 7578372 B1 20090825 (2009)

Applications Octanal is a useful reagent in the design and synthesis of tetrahydro-β-carboline-3-carbohydrazide derivatives which exhibit antiviral, fungicidal, and insecticidal activies.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Liu, Y., et al.: J. Agr. Food Chem., 62, 9987 (2014)

Applications Isotope labelled o-Cresol is a compound used as a disinfectant and have also been used as antiseptic in surgery.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Razavi, S.M., et al.: Nat. Prod. Res., 26, 2148 (2012); Asadollahi-B. M., et al.: Environ. Toxicol. Pharmacol., 34, 826 (2012);

Applications 1-(4-Nitrophenyl) 1,4-Benzenedicarboxylate is a useful research chemical.

Applications Potentially mutagenic compound. Dyes and metabolites, Environmental Testing.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dairou, J., et al.: Toxicol. App. Pharmacol., 236, 366 (2009), Toropov, A., et al.: Chem. Biol. Drug Design, 73, 482 (2009),

Applications Quinoxaline is a reagent used in the synthesis of quinoxaline diimides as small molecule non-fullerene acceptors for organic solar cells.

Applications Meprylcaine Hydrochloride is a local anaesthetic used in medical procedures.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Morita, K. et al.: Brain Res., 1057, 153 (2005); Toshihiro, D. et al.: Curr. Med. Chem., Cent. Nerv. Sys. Agents, 5, 89 (2005);

Applications A fatty acid found in Amaranth oil; it shows inhibitory activity.
References Fidler, N., et al.: J. Lipid Res., 41, 1376 (2000), Yang, T., et al.: Food Chem., 80, 473 (2003), Gamel, T., et al.: J. Food Lipids, 14, 323 (2007),

Applications 1,6-Dihydroxynaphthalene-d6 is the isotopically labeled compound form of 1,6-Dihydroxynaphthalene(D454158) which is used in preparing rhodol-based fluorescent probes for the detection of fluoride ion and its application in water, tea and live animal imaging.
References Jin, Xilang. et al., SPECTROCHIM. ACTA. A. 224, 117467(2020);

Applications Norethylmorphine is used in formation of ethylmorphine. Ethylmorphine is a metabolite in liver hepatocytes.
References Xu, B., et al.: Pharmacology & Toxicology, 73, 35 (1993),

Applications 1,4-Diphenylbutane (cas# 1083-56-3) is a useful research chemical.

Stability Hygroscopic
Applications Esculentoside A is a saponin isolated from the root of Phytolacca esculenta. Modulates the immune response. and effects cell proliferation and apoptosis in cells. Anti-inflammatory. 500
References Ma, H. et al.: Arch. Med. Sci., 9, 354 (2013); Zhong, W. et al.: J. Surg, Res., 185, 364 (2013);

Applications BENZAMIDINE (cas# 618-39-3) is a useful research chemical.