Organic Building Blocks

Applications Azosemide is a high-ceiling diuretic agent. It is used in the treatment of edematous states and hypertension.
References Ogawa, K., et al.: Inter. J. Clin. Pharm. Ther. Toxicol., 22, 401 (1984); Suh, O., et al.: Biopharm. Drug Disposition., 24, 275 (2003)

Applications 3-Benzoylpropanoic Acid (cas# 2051-95-8) is a compound useful in organic synthesis.

Applications Cyclizine Lactate is a lactate salt of Cyclizine (C987805, HCl salt) which is a piperazine derivative with anti-emetic activity that is useful in the prevention and treatment of nausea and vomiting associated with motion sickness.
References Kuntzman, R., et al.: J. Pharmacol. Exp. Ther., 158, 332 (1967), Walker, R., et al.: Eur. J. Pharm. Sci., 4, 301 (1996), Dumasia, M., et al.: Xenobiotica, 32, 795 (2002)

Applications Isotope labelled o-Cresol is a compound used as a disinfectant and have also been used as antiseptic in surgery.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Razavi, S.M., et al.: Nat. Prod. Res., 26, 2148 (2012); Asadollahi-B. M., et al.: Environ. Toxicol. Pharmacol., 34, 826 (2012);

Stability Light Sensitive
Applications Isodrine is a highly toxic compound that is used as a pesticide in the agricultural industry.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gaines, T.: Toxicol. Appl. Pharm., 14, 515 (1969); Walton, I., et al.: Org. Lett., 14, 2686 (2012)

Applications Solvent Red 52 is used in method for production of Poly(trimethylene furandicarboxylate) using Zinc catalyst.
References Poladi, Raja Hari, et al.: PCT Int. Appl., (2018);

Applications n-Heptane is used a component of blended fuel compositions as well as a solvent in organic chemical reactions.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ding, Y. et al.: J. Haz. Mat., 271, 82 (2014); Xu, H. et al.: J. Chem. Eng. Dat., 59, 1281 (2014);

Applications 1-(Methylthio)diphenylmethane is used in preparation of Thiols and Thioethers via reduction or methylation of Thiones with Lithium Diisopropylamide.
References Gebert, A., et al.: Helvetica Chimica Acta, 97, 931-938 (2014);

Stability Light Sensitive
Applications Used in the manufacturing plastics; synthetic rubber; resins; insulator.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meyer. H.J., et al.: Arzneim.-Forsch., 19, 617 (1969), Pahwa, R., et al.: Vet. Hum. Toxicol., 35, 516 (1993),

Applications 6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol is an intermediate used in the preparation of pyridoxine (vitamin B6).
References Harris, E. E., et al.: J. Org. Chem., 27, 2705 (1962), Naito, T., et al.: Yakugaku Zasshi, 79, 1277 (1959)

Applications 2,2,2-Triphenylacetic Acid is used in preparation of Rhodium(II) Tetramethyl-benzenedipropioate complex, other Carboxylate complexes, and their catalytic activity.
References Martinez-Castro, E., et al.: Organic Process Research & Development, et al.: 24, 1207-1212 (2020);

Applications 1-(2-Hydroxyethyl) Ester, 1,4-Benzenedicarboxylic Acid could be used to condition bacteria to enable it to target polymer polyethylene terephthalate (PET).
References Kumar, V., et al.: J. Environ. Chem. Eng., 8, 103977 (2020);

Stability Air Sensitive
Applications p-Cresidine is a reagent used in the preparation of enaminones acting as anticonvulsants. Also used in the preparation of crescent oligoamides. Dyes and metabolites, Environmental Testing.
References Zhu, J. et al.: J. Am. Chem. Soc., 122, 4219 (2000); Scott, K. et al.: J. Med. Chem., 36, 1947 (1993);

Applications 1-(4-Nitrophenyl) 1,4-Benzenedicarboxylate is a useful research chemical.

Applications Benzyl Oxirane-2-carboxylate is an intermediate in the synthesis of 3-(2-Methoxyphenoxy) Lactic Acid (M265500) which is a metabolite of the Guaifenesin (G810500), a centrally acting muscle relaxant with expectorant properties.
References D.G. Workmann et. al. Curr. Ther. Res. 41 1751 (1980).

Applications L-AP3 is a selective antagonist of the PI-linked metabotropic glutamate response.

Applications para-Topolin can be used for biological study for evaluation of antioxidant activity and capacity of some natural N6-substituted adenine derivatives (cytokinins) by fluorimetric and spectrophotometric assays.
References Brizzolari, A., et al.: J. Chromatogr. B., 1019, 164-168 (2016)

Applications Triphthazine Sulfoxide is used for the decomposition of sulfoxide metabolites of phenothiazine antipsychotics during gas chromatographic analysis.
References Hall, K., et al.:J Chromatogr. B. Biomed. Sci. Appl. 231, 200 (1982)

Stability Hygroscopic
Applications Esculentoside A is a saponin isolated from the root of Phytolacca esculenta. Modulates the immune response. and effects cell proliferation and apoptosis in cells. Anti-inflammatory. 500
References Ma, H. et al.: Arch. Med. Sci., 9, 354 (2013); Zhong, W. et al.: J. Surg, Res., 185, 364 (2013);

Applications Occurs in coal tar. Is formed during distillation of coal, in very small amount during distillation or pyrolysis of many fats and oils. Chrysene is one of the basic polycyclic aromatic hydrocarbon (PAH) which is toxic environmental pollutant and consistently exposed to sunlight. However, little information is available on its photogenotoxicity.  The objective of the present study was to analyze the effects of Chrysene, under environmental intensity of UVB (0.6 mW/cm2) in human skin epidermal cell line (HaCaT).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anderson, D., et al.: Mutat. Res., 307, 261 (1994), Diamond, S., et al.: Environ. Toxicol. Chem., 25, 3015 (2006), Fotakis, G., et al.: Toxicol. Lett., 160, 171 (2006),

Applications Hexamoll is one of the new plasticizers being used, which shows a structure similar to the most commonly used o-phthalates. It is favoured to substitute DEHP by DINCH as plasticizer for flexible poly(vinyl chloride).
References Crespo, J., et al.: J. Appl. Polym. Sci.,104, 1215 (2007).

Applications BENZAMIDINE (cas# 618-39-3) is a useful research chemical.

Applications Paraffin Oils is a useful organic solvent for isolating the nucleus of the gian amphibian oocyte.
References Praine, P., et al.: Biotechniques, 13, 238 (1992);

Applications 2,5,6,7-tetrahydro-1H-azepin-2-one (cas# 2228-79-7) is a useful research chemical.

Stability Hygroscopic
Applications Guaiacol-beta-D-gentiobioside, is a Guaiacol Conjugate, that has shown to present in fermentation of grapes that had been exposed to bushfire smoke and can potentially yield unpalatable, smoke-affected wine.
References Hayasaka, Y.m et al.: J. Arg. Food Chem., Vol. 58, Issue 4, P: 2076; 2081 (2010);

Applications Tetrachloroauric Acid, is used for the recovery, concentrating, purification, and analytical determinations of gold. It is the precursor used in the purification of gold by electrolysis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mironov, I. V., et al.: Russian J. Inorg. Chem., 57, 610 (2012); Feather, A., et al.: J. Southern Africa Inst. mining Metal., 169 (1997);

Stability Light Sensitive
Applications Protected Caffeic Acid
References Kurata, A., et al.: J. Biotechnol., 148, 133 (2010), Buzzi, F., et al.: Eur. J. Med. Chem., 44, 4596 (2009), Xu, G., et al.: Arch. Pharm., Res., 32, 1215 (2009),

Applications Polyquaternium 11 is found to suppress melanin elution in shampoo thus may prevent hair from dulling after repeated shampoo use.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hagihara, M.: Frag. J., 40, 23 (2012)

Applications Dihydroresveratrol is a natural phytoestrogen.

Applications 3-Penten-1-yne is used in the preparation of aliphatic and terminal alkynes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Hygroscopic
Applications 2-Hydroxy-5-Amino-N-(2-carboxy-4-aminophenyl)benzoic Acid is an impurity from the synthesis of Mesalamine (M258100).
References Friedman, G., et al.: Am. J. Gastroenterol., 81, 141 (1986); Tursi A., Expert Opin. Pharmacother., 6, 69 (2005);

Applications Forest fires are actually beneficial for ecosystems, provided they don’t happen too often. After a fire, plants germinate and grow incredibly fast. KAR1 is a compound in smoke responsible for promoting the seed germination of a wide range of plant species. The researchers named the compounds “the karrikins”, for “karrik”, an aboriginal word for smoke.
References Sakuma, H., et al.: .Agric Biol. Chem., 45, 443 (1981), Stevens, J., et al.: Plant Soil, 298, 113 (2007), Nelson, D., et al.: Plant Physiol., 149, 863 (2009),

Stability Very Hygroscopic
Applications Accumulation and excretion of 2-Hydroxyhexanedioic Acid (with 2-ketoadipic and 2-aminoadipic) in urine can be caused by 2-ketoadipic acidemia, probably without adverse phenotypic effects , due to deficiency of 2-ketoadipic dehydrogenase.
References Svendsen, J., et al.: J. Chromatogr., 337, 9 (1985); Przyrembel, H., et al.: Clin. Chim. Acta 58, 257 (1975).

Applications Arecoline has shown regulatory properties of controlling plasminogen activator inhibitor-1 expression in human buccal mucosa fibroblasts.
References Tsai, C.H., et al.: J. Oral. Pathol. Med., 44, 669 (2015);

Applications Vitamin K3 (V676130) derivative. Menaquinol analog. Induces mutations in Escherichia coli nitrate reductase A.
References Zhao, Z. et al., Biochem., 42, 14225 (2003); Zhao, Z. et al., Biochem., 42, 5403 (2003)

Applications An α-keto ester derivative.

Applications Ferulic Acid Methyl Ester is a derivative of Ferulic Acid (F308900), used as an antioxidant and food preservative. It has less antioxidant capacity than ferulic acid.
References Smart, M.G., et al.: Aust. J. Plant Physiol., 6, 485 (1979), Chen, C., et al.: J. Food Lipids, 2, 35,1995, Benzie, I., et al.: Anal. Biochem. 239, 70 (1996), Nardini, M., et al.: Food Chem., 79, 119 (2002), Lee, J., et al.: J. Agric. Food Chem., 52, 2647 (2004),

Stability Hygroscopic
Applications 3-Phenylglutaric Acid is useful in the synthesis of manganese catalysts for the stereoselective synthesis of cyclealkanes.
References Jana, A., et al.: ACS. Cat., 10, 2615-2626 (2020)

Impurity Propafenone EP Impurity A; Propafenone BP Impurity A; Propafenone USP Impurity A
Applications 2’-Hydroxy-3-phenylpropiophenone (Propafenone EP Impurity A; Propafenone BP Impurity A; Propafenone USP Impurity A) is a metabolite of Propafenone (P757500).
References Hege, H.G. et al.: Arzneim.-Forsch., 34, 972 (1984);

Applications Glycidyl Caprate is an epoxy monomer used as a crosslinking agents for alkyd coatings.
References Sorokin, M.F. et al.: Lakokras. Mat. Ikh Prim., 5, 9 (1979);

Applications p-SCN-Bn-NOTA is a bifunctional chelating agent.
References Sarkar, S., et al.: J. Med. Chem., 61, 385 (2018)

Stability Light Sensitive
Applications D-α-Tocopherol Quinone is an vitamin E derivative that exhibits antioxidant properties. D-α-Tocopherol Quinone has been shown to partially restore the activity of NADH dehydrogenase and used to investigate the electron transport system in rat hepatocyte and human erythrocyte.
References Sun, I. L., et al.: Proc. Natl. Acad. Sci. USA 89, 11126 (1992); Hosomi, A., et al.: FEBS Lett. 409, 105 (1997)

Applications 10-NONADECANONE (cas# 504-57-4) is a useful research chemical.

Applications 2-Methyldibenzofuranis used in volatile composition of biomass tars used for liquid engine fuels with properties similar to gasoline and diesel fuels.
References Soltes, E. J., et al.: Biomass Convers. 5, 1 (1984)

Applications 1,6-Dihydroxynaphthalene-d6 is the isotopically labeled compound form of 1,6-Dihydroxynaphthalene(D454158) which is used in preparing rhodol-based fluorescent probes for the detection of fluoride ion and its application in water, tea and live animal imaging.
References Jin, Xilang. et al., SPECTROCHIM. ACTA. A. 224, 117467(2020);

Applications Sodium Acrylate is the acid form of Acrylic Acid (A191350); which is an antibacterial agent.
References Kind, T., et al.: Anal. Biochem., 363, 185 (2007), Spratlin, J., et al.: Clin. Cancer Res., 15, 431 (2009),

Applications α-Desethyl Butamirate is an impurity in the synthesis of Butamirate (B690025), an antitussive drug.
References Wang, T., et al.: J. Pharm. Biomed. Anal., 23, 867 (2000), Lasztity, A., et al.: Microchem. J., 73, 59 (2002), Wang, L., et al.: J. Pharm. Biomed. Anal., 33, 961 (2003), Lewen, N., et al.: J. Pharm. Biomed. Anal., 35, 739 (2004),

Applications α-Cyclohexyl-benzeneacetic Acid is a useful synthetic intermediate. It was used as one of the reactants to prepare phenylureidobenzazepinones as cholecystokinin-B receptor antagonists. It can also be used to synthesize benzimidazole derivatives as potent AMP-activated protein kinase activators.
References Lowe, J., et al.: J. Med. Chem., 37, 3789 (1994); Charton, J., et al.: Bioorg. Med. Chem., 14, 4490 (2006)

Applications Mineral Oil can be used as preferred lubricant for aerosol lubricant and dispensing method. An aerosol container containing a propellant and a highly hydrogenated mineral oil lubricant for the lubrication of gaskets in pipe segments.
References Green, R., et al.: U.S., US 7578372 B1 20090825 (2009)

Applications 4-Hydroxyanisole commonly known as Mequinol, is a topical depigmenting agent that functions as a tyrosinase inhibitor. This is a labeled analog.
References Fleischer, A. et al.: J. Am. Acad. Dermatol., 42, 459 (2000);

Applications 2-Ethyl-3,6-dimethylpyrazine is a flavour-active and non-volatile compound identified in thermally treated yeast extracts. It is also useful in the synthesis of new flavour additive species of pyrazines.
References Alim, A., et al.: J. Sci. Food Agric., 98, 3774 (2018); Lai, M., et al.: J. Therm. Anal. Calorim., 128, 1627 (2017)

Applications 3-Oxohexanedioic Acid is a degradation product of catechol in the presence of hydrogen peroxide; Also, it is derived from 3-Oxohexanedioic Acid Diethyl Ester (O856830), which is an intermediate used to prepare CMPF (C595000) which is a drug-binding inhibitor which is also a constituent of urine. CMPF can inhibit specific T4 binding in serum by increasing the free concentration of direct competitors.
References Gogoi, A., et al.: Chem. Eng. J., 311, 153-162 (2017); Mabuchi, H., Nakahashi, H.: Nephron, 44, 277 (1986); Lim, C.F., et. al.: Metabolism Clin. Exp., 42, 1468 (1993)

Applications (±)-Cyhalothric acid (CAS# 68127-59-3) is a useful research chemical compound.

Applications TETRAHYDROFURFURYL ACRYLATE (cas# 2399-48-6) is a useful research chemical.

Applications Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.
References Cornford, E.M., et al.: J Clin Invest, 63, 1241-1248 (1979)

Applications Used for fragrance compositions and perfumes with long-lasting fragrance.
References Ternes, T., et al.: Sci. Total Environ., 225, 81 (1999), Simonich, S., et al.: Environ. Sci. Technol., 36, 2839 (2002) Metcalfe, C., et al.: Environ. Toxicol. Chem., 22, 2872 (2003),

Applications A synthetic musk fragrance compound (polycyclic musk) used in personal care products, and can be found in the environment and the human body.
References Mori, T. et al.: Env. Sci., 14, 195 (2007); Int. J. Hygiene Env. Health, 123, 124 (2010); Yamauchi, R. et al.: Aquatic Toxic., 90, 261 (2008);

Stability Hygroscopic
Applications EPTC is a pesticide, S-Ethyl-N,N-dipropylthiocarbamate

Applications 1-Methylpiperazine-2,2,3,3,5,5,6,6-d8 is the labeled version of 1-Methylpiperazine (Imatinib EP Impurity G)(M326495) is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug. It is a COVID19-related research product.Is used in preparation of Imidazopyridine compounds for the treatment of inflammatory disorders.
References Mallevais, M.L. et al.: Biochimie, 66, 477 (1984); Van der Plas, Steven E., et al.: PCT Int. Appl., (2019);

Applications Di-tert-octyl Disulfide (cas# 29956-99-8) is a useful research chemical.

Applications Quinoxaline is a reagent used in the synthesis of quinoxaline diimides as small molecule non-fullerene acceptors for organic solar cells.

Applications N-Caprylic anhydride

Applications Disodium NADP is used in method for preparing 2,4-Diamino Butyric Acid by enzyme catalysis.
References Yu, T., et al.: Faming Zhuanli Shenqing, (2020);

Applications Pentaethylene glycol dichloride is a useful synthetic intermediate. Pentaethylene glycol dichloride is used as a reagent to prepare various Crown Ethers.
References Peng, C., et al.: J. Appl. Polym. Sci., 70, 501 (1998); Park, S., et al.: Chem. Lett., 35, 1024 (2006)

Stability Moisture Sensitive
Applications Succinic Anhydride is a useful compound in the paper manufacturing process.
References Ikeda, S., et al.: Jpn. Tokkyo Koho (2021), JP 6822596 B1

Applications p-Toluenesulfonic Acid Hydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);

Stability Hygroscopic
Applications N'-Formylkynurenine is a photooxidation product of Tryptophan (T947200), and is also used as a photosensitizer of near-ultraviolet radiation by generating singlet oxygen and superoxide.
References Grossweiner, L.: Curr. Eye Res., 3, 137 (1984); Møller, I. & Kristensen, B.: Free Radical Bio. Med., 40, 430 (2006); Pileni, M., et al.: J. Phys. Chem., 80, 1804 (1976)

Applications 1,9-Nonanediol diacrylate (cas# 107481-28-7) is a useful research chemical.

Applications 4-n-Nonylphenol-2,3,5,6-d4 is the labelled isotope compound of 4-Nonyl Phenol(N650430) which is used in the process for the manufacture of 5-nonyl salicylaldoxime, which is used for the selective purification and concentration of copper ions.
References Bhikulal, P. S., et al.: From Indian Pat. Appl. (2005) IN 2005MU01163 A 20051118

Applications An metabolite of Cotinine. In equilibrium with 5’-Hydroxycotinine the cyclized form.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Morselli, P.L, et al.: J. Med. Chem., 10, 1033 (1967); Murphy, S.E. et. al.: Chem. Res. Toxicol. 12, 639 (1999)

Applications 1-Methyl-5-p-toluoylpyrrole-2-acetic acid (cas# 26171-23-3) is a useful research chemical.

Applications 4-Hydroxybenzotriazole (cas# 26725-51-9) is a useful research chemical.

Applications Meprylcaine Hydrochloride is a local anaesthetic used in medical procedures.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Morita, K. et al.: Brain Res., 1057, 153 (2005); Toshihiro, D. et al.: Curr. Med. Chem., Cent. Nerv. Sys. Agents, 5, 89 (2005);

Applications Lasofoxifene intermediate.
References Tatee, T., et al.: J. Med. Chem., 22, 1509 (1979), Wellmann, F., et al.: J. Biosci., 46, 252 (1991),