Organic Building Blocks

Applications p-Vinylguaiacol-d3 is the isotope labelled analog of p-Vinylguaiacol (V424960); an aromatic substance, one of the compounds responsible for the natural aroma of buckwheat, and also one of the major pyrolytic products of (E)-N-[(4-hydroxy-3-methoxy)-phenethyl]-3-[(3-methoxy-4-O-β-D-glucopyranosyloxy) phenyl] acrylamide; a new gycloside in tobacco.
References Janes, Damjan., et al.: Food Chem., 112(1), 120-124 (2009); Zhou, Rong., et al.: Yancao Keji, (7), 34-36, 42 (2013)

Applications α-Methyl-1-naphthaleneacetic Acid-d3 Ethyl Ester, is a labeled building block used in various chemical synthesis.

Applications Hexanoic Anhydride, is used as a reactant in the total synthesis of acremomannolipin A via steroselective β-mannosylation of 4,6,-O-benzylidene-protected mannosyl sulfoxide with a D-mannitol derivative.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tsutsui, N., et al.: Tetrahedron Lett. 54, 451(2013)

Applications An impurity found in tramadol (T712500).
References Medvedovici, A. et al.: J. Pharmac. Biomed. Anal., 34, 67 (2004);

Applications 5-Methyl-d3-amino-4-nitro-2,1,3-benzoselenadiazole (cas# 1246815-24-6) is a compound useful in organic synthesis.

Applications Triglycol is used in a mixture with 2-amino-2-methyl-1-propanol in a CO2 absorption-regeneration process.
References Zheng, C., et. al.: Ind. Eng. Chem. Res., 51, 11236 (2012)

Applications 2-Amino-2-methylpropanenitrile (cas# 19355-69-2) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Oesterlin, R., et al.: J. Med. Chem., 20, 1068 (1977), Battmann, T., et al.: J. Steroid Biochem. Mol. Biol., 48, 55 (1994),

Applications 5-Methyl-2-(phenylsulfonyl)thiazole is an intermediate used in the synthesis of Deschloro-2-phenylsulfonyl-thiamethoxam (D290790), which is an impurity of thiamethoxam (T344180), which is a neonicotinoid insecticide. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens.
References Oliver, J., et al.: J. Environ. Horticult., 28, 135 (2010), Ghosh, A., et al.: J. Entomol. Res., 34, 35 (2010), Chem. and Eng. News 90: 10 (2012)

Applications An intermediate of Ticlopidine (T438325). Thieno[3,2-c]pyridine derivatives are used for treatment of inflammatory disorders.
References Malicorne, G., et al.: Eur. J. Med. Chem., 26, 3 (1991), Wagner, G., et al.: Pharmazie, 48, 95 (1993), El-Abadelah, M., et al.: Eur. J. Med. Chem., 33, 33 (1998),

Applications 3-Nitro-1,8-naphthalic anhydride is a reagent used to synthesize a monoboronic acid fluorescent sensor that exhibits emission suitable for ratiometric testing and also displays sensitivity for glucose relative to fructose and galactose. 3-Nitro-1,8-naphthalic anhydride is also used as a starting reagent in the synthesis of 5-substituted naphthalimide derivatives which exhibit high anti-cancer activity.
References Haishi, C., et al.: Org. Lett., 4, 1503 (2002); Ingrassia, L., et al.: Curr. Med. Chem., 16, 1192 (2009);

Applications N-Boc-Cefprozil is an intermediate in the synthesis of Ethoxy Carbonyl Cefprozil (E/Z Mixture) (E891743). Ethoxy Carbonyl Cefprozili is an impurity of Cefadroxil (C235750), a semi-synthetic cephalosporin antibiotic. Antibacterial.
References Buck, R.E., et al.: Antimicrob. Agents Chemother., 11, 324 (1977);

Applications DI-TERT-BUTYLSILANE (cas# 30736-07-3) is a useful research chemical.

Applications 3-Bromo-5-methylphenol is a useful raw material for organic synthesis and pharmaceuticals.
References Golinski, M., et al.: Eicosanoids, 5, 87 (1992); Baldwin, J. E., et al.: Tetrahedron, 47, 5603 (1991); Ren, Z., et al.: Org. Lett., 18, 4958 (2016)

Applications 17alpha-Ethynylestradiol-16,16-d2 3-Methyl Ether is a useful isotopically labeled compound of Mestranol (M258755)

Applications N-Norbimatoprost is a useful reagent for developing methods for treating epithelial-related conditions including hair loss.N-Norbimatoprost is also an analog of Bimatoprost (B386800), an synthetic prostamide and structurally related to prostaglandin F2α.
References Lipkin, P. and Lubit, B.: US 7514474 B2 20090407 (2009); Lipkin, P. and Lubit, B U.S. Pat. Appl. Publ. US 20110002866 A1 20110106 (2011); Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001); Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003); Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004)

Applications Tri(4-morpholinyl)phosphine oxide (cas# 4441-12-7) is a useful research chemical.

Applications N-Methyladrenalone Hydrochloride-D3 is a reagent in the synthesis of rac N-Methyl Epinephrine-d6 Hydrochloride (>90%) (M304302) which is the N-methylated analogue of the sympathomimetic hormone Epinephrine (E588585). Recent studies suggest that N-Methylepinephrine may be synthesized from Epinephrine by phenylethanolamine N-methyltransferase present in the brain.
References Kajita, M. et al.: Nip. Iyo Masu Sup. Gak. Kon., 19, 107 (1994); Plummer, C.J. et al.: Eur. J. Med. Chem., 148, 481 (1988);

Applications 4-(4-Methylpiperazin-1-ylmethyl)Benzoic Acid (cas# 106261-48-7) is a useful research chemical.

Applications 2-(2-Hydroxypropoxy)propan-1-ol (cas# 25322-69-4) is a useful research chemical.

Applications 3-Amino-N-(3-carbamoyl-1-carboxypropyl)phthalamic Acid is a useful research chemical.

Applications 4-(1,4-Dihydro-2,4-dioxo-3(2H)-quinazolinyl)-benzeneacetic Acid is a useful research chemical.

Applications Deoxysepiapterin is used for the analysis and in the identification of pterins in human urine. Isolation and preparation of pterin from biological materials.
References Fukushima, T., et al.: J. Biol. Chem., 247, 4549 (1972); Fukushima, T., et al.: Methods Enzymol., 66, 508 (1980);

Applications N-Boc-Cefprozil O-Ethyl Formate is an intermediate in the synthesis of Ethoxy Carbonyl Cefprozil (E/Z Mixture) (E891743). Ethoxy Carbonyl Cefprozili is an impurity of Cefadroxil (C235750), a semi-synthetic cephalosporin antibiotic. Antibacterial.
References Buck, R.E., et al.: Antimicrob. Agents Chemother., 11, 324 (1977);

Applications 3-Methylpentanedioic-2,2,4,4-d4 Acid (CAS# 1219798-68-1) is a useful isotopically labeled research compound.

Applications 5-ethylhydantoin (cas# 15414-82-1) is a useful research chemical.

Applications 2-Pyridineacetonitrile is a useful reagent for the organic synthesis and studies of pyridyl and dihydropyridyl analogs of meperidine and ketobemidone with their antinociceptive activities.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Buolamwini, J. K., et al.: Drug Des. Deliv., 7, 19 (1990)

Applications N,N-Dimethylethanolamine-d10 (OH) is a useful isotopically labeled compound of 2-Dimethylaminoethanol (D471170)

Applications N-​(3,​4-​Dicyanophenyl)​-​2-​hydroxy-​2-​methylpropanamide is a useful research chemical.

Applications n-Pentylbenzene-2,3,4,5,6-d5 (CAS# 68639-73-6) is a useful isotopically labeled research compound.

Applications 2-((2-((Methylsulfonyl)oxy)propanoyl)oxy)propanoic Acid is a useful research chemical.

Applications Miglustat N-Oxide is a useful synthetic intermediate.

Applications 2-Methyl-3-phenylpyrazine (cas# 29444-53-9) is a useful research chemical.

Applications Allergosil is used in preparation of Sulfonic Acid Magnesium Chloride Salts as Sulfur-based electrolyte solution for Magnesium secondary batteries.
References Mori, G., et al.: PCT Int. Appl., (2020);

Applications 4-Butyl-(benzenamine-13C6) is labelled 4-Butylbenzenamine.

Applications 2,2'-Dimethyl-[1,1'-biphenyl]-4,4'-diamine (cas# 84-67-3) is a useful reagent for manufacturing cured films and semiconductor devices.
References Aoshima, T., et al.: PCT Int. Appl. (2020), WO 2020226131 A1

Applications L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid methyl ester hydrochloride (CAS# 83159-19-7) is a useful research chemical compound.

Applications 2-(((2-Cyanoethoxy)(diisopropylamino)phosphino)oxy)acetic Acid is a useful intermediate for organic synthesis.

Applications 4-Methyl-4-vinyl-4-butanolide is an intermediate in the synthesis of γ-CEHC (C249200) which is a metabolite of γ-Tocopherol (T526140); one of the naturally occurring forms of Vitamin E found most abundantly in soybean and corn oils.
References Emerson, et al.: Science, 83, 421 (1936); Bieri, J.G., et al.: J. Nutr., 104, 850 (1974); Jiang, Q., et al.: Am. J. Clin. Nutr., 74, 714 (2001); Kiyose, C., et al.: J. Clin. Biochem. Nutr., 56, 143 (2015)

Applications Lincomycin Sulfone is a research reagent with potential antibiotic activities
References Sztaricskai, F. et al.: J. Antibiotics, 50, 866 (1997)

Applications: TSTU is used as a peptide coupling reagent in solvent systems.
References Knorr, R., et. al.: Pept. 1990, Proc. Eur. Pept. Symp., 21st, 62-4 (1991)