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Cytoskeletal Signaling

Cytoskeletal Signaling

Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.

Found 1382 products of "Cytoskeletal Signaling"

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  • Filanesib TFA

    CAS:
    <p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>
    Formula:C22H23F5N4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:534.5
  • PKC β pseudosubstrate

    CAS:
    <p>Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).</p>
    Formula:C177H294N62O38S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3994.84
  • 7-Epi-10-oxo-docetaxel

    CAS:
    <p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>
    Formula:C43H51NO14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:805.86
  • α2β1 Integrin Ligand Peptide TFA


    <p>α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a</p>
    Formula:C16H23F3N4O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:504.37
  • β-catenin-IN-37

    CAS:
    <p>β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI.</p>
    Formula:C13H9N9O
    Color and Shape:Solid
    Molecular weight:307.277
  • Gly-Arg-Gly-Asp-Ser

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>
    Formula:C17H30N8O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.47
  • TC113


    <p>TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.</p>
    Formula:C37H50F2N12O13
    Color and Shape:Solid
    Molecular weight:908.86
  • FAK-IN-7

    CAS:
    <p>FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.</p>
    Formula:C16H13N3OS
    Purity:98.18%
    Color and Shape:Solid
    Molecular weight:295.36
  • DSPE-PEG5000-cRGD


    <p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>
    Color and Shape:Odour Solid
  • PROTAC BCR-ABL1 ligand 1

    CAS:
    <p>GMB-475 is a PROTAC ligand targeting BCR-ABL1 for degradation via E3 ligase recruitment.</p>
    Formula:C17H12F3N3O2
    Color and Shape:Soild
    Molecular weight:347.29
  • Bisindolylmaleimide III

    CAS:
    <p>Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6</p>
    Formula:C23H20N4O2
    Purity:98.6%
    Color and Shape:Solid
    Molecular weight:384.43
  • Zolbetuximab

    CAS:
    <p>Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2 for certain gastrointestinal and pancreatic cancers.</p>
    Purity:95.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97%+
    Color and Shape:Liquid
    Molecular weight:147.09 kDa
  • 6-Epi-ophiobolin G


    <p>6-Epi-ophiobolin G (MHO7) is a marine-derived fungal metabolite that serves as an orally active Akt inhibitor capable of crossing the blood-brain barrier. It effectively inhibits the proliferation of glioblastoma (GBM) cells and promotes apoptosis. 6-Epi-ophiobolin G (MHO7) is suitable for research in glioblastoma studies.</p>
    Formula:C24H32O2
    Color and Shape:Solid
    Molecular weight:352.24023
  • Tubulin inhibitor 24

    CAS:
    <p>Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.</p>
    Formula:C22H21N3O3
    Purity:99.99%
    Color and Shape:Solid
    Molecular weight:375.42
  • 4,4'-Di-O-methylellagic acid

    CAS:
    <p>4,4'-Di-O-methylellagic acid is a useful organic compound for research related to life sciences. The catalog number is T125016 and the CAS number is 3374-77-4.</p>
    Formula:C16H10O8
    Color and Shape:Solid
    Molecular weight:330.248
  • Echistatin TFA


    <p>Echistatin TFA: a minimal RGD protein from snake venom; inhibits platelet aggregation and bone resorption; targets αIIbβ3, αvβ3, α5β1.</p>
    Color and Shape:Odour Solid
  • AS-605240 potassium


    <p>AS-605240 (potassium) is an orally active PI3Kγ inhibitor with an IC50 of 8 nM and a Ki of 7.8 nM. It inhibits MCP-1 and CSF1-induced PKB phosphorylation with IC50 values of 0.181 µM and 0.550 µM, respectively. In mouse models of peritonitis induced by RANTES (CCL5) and thioglycolate, AS-605240 (potassium) reduces neutrophil recruitment, showing EC50 values of 9.1 mg/kg and 10 mg/kg. Additionally, AS-605240 (potassium) ameliorates arthritis induced by αCII-IA in mice.</p>
    Formula:C12H6KN3O2S
    Color and Shape:Solid
    Molecular weight:294.98178
  • p5 Ligand for Dnak and DnaJ

    CAS:
    <p>P5 is a nonapeptide ligand for DnaK/DnaJ, mimicking the key sites of mitochondrial aspartate aminotransferase presequence.</p>
    Formula:C44H81N15O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1028.27
  • DSPE-PEG1000-cRGD


    <p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>
    Color and Shape:Odour Solid
  • MAL3-101

    CAS:
    <p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>
    Formula:C54H66N4O10
    Color and Shape:Solid
    Molecular weight:931.12