Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1537 products for "Cytoskeletal Signaling".
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Myosin V-IN-1
CAS:Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.Formula:C29H26N6O3SPurity:98.35% - 98.89%Color and Shape:Yellow SolidMolecular weight:538.62Ref: TM-T72060
1mg298.00€5mg628.00€1mL*10mM (DMSO)642.00€10mg893.00€25mg1,324.00€50mg1,791.00€100mg2,412.00€Foxy-5
CAS:Foxy-5 is a wnt5a peptide mimeticFormula:C26H42N6O12S2Purity:98%Color and Shape:SolidMolecular weight:694.77ALB-109564 dihydrochloride
CAS:ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.Formula:C47H62Cl2N4O9SPurity:98%Color and Shape:SolidMolecular weight:929.99para-amino-Blebbistatin
CAS:para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.Formula:C18H17N3O2Color and Shape:SolidMolecular weight:307.353[Ala113]MBP(104-118)
CAS:Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).Formula:C67H104N20O19Purity:98%Color and Shape:SolidMolecular weight:1493.68Epothilone F
CAS:Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Formula:C27H41NO7SColor and Shape:SolidMolecular weight:523.68MINT1526A
MINT1526A (RG-7594) is a humanized IgG1 monoclonal antibody inhibitor targeting α5β1 integrin, exhibiting significant anti-angiogenic activity. This compound is applicable in cancer research.NPC-15437 dihydrochloride
CAS:NPC-15437 dihydrochloride is a PKC inhibitor blocking enzyme activity and phorbol ester binding, selective over other kinases, in cellular signaling research.Formula:C25H52Cl2N4O2Color and Shape:White SolidMolecular weight:511.62αvβ5 integrin-IN-1
CAS:αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.Formula:C25H28F3N3O3Color and Shape:SolidMolecular weight:475.512Wnt pathway inhibitor 4
CAS:Wnt pathway inhibitor 4 is a small molecule antimicrobial agent with antibacterial and antiproliferative activity against cancer cells.Formula:C19H15BrN2O5Purity:98.91%Color and Shape:SolidMolecular weight:431.24Phomopsinamine
CAS:Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Formula:C32H43ClN6O8Color and Shape:SolidMolecular weight:675.17Foxy-5 Ammonium Salt
Foxy-5 Ammonium Salt, a WNT5A mimetic, blocks epithelial cancer cell migration without β-catenin impact and curbs prostate cancer spread.Formula:C26H46N7O12S2Purity:97.70%Color and Shape:White SolidMolecular weight:712.26Ref: TM-TP1565L1
1mg90.00€5mg288.00€1mL*10mM (DMSO)309.00€10mg430.00€25mg705.00€50mg982.00€100mg1,324.00€BChE-IN-41
BChE-IN-41 is a highly selective butyrylcholinesterase (BChE) inhibitor with an IC50 of 12 nM and a Ki of 6.6 nM. It exhibits significant brain permeability, with a brain-to-plasma ratio of 9.0. BChE-IN-41 enhances cognitive function in mice with scopolamine and Aβ1-42-induced symptoms of Alzheimer's disease.PLH1215
CAS:PLH1215 is an effective AHR inhibitor that can be used for the prevention and treatment of cancer. Cost-effective and quality-assured.Formula:C19H26N4OPurity:99.88% - 99.98%Color and Shape:SolidMolecular weight:326.44LDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurity:98%Color and Shape:SolidMolecular weight:1368.53Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Formula:C45H54F2N4O8·xC4H6O6Purity:98%Color and Shape:SolidMolecular weight:967.02Ref: TM-T6722
2mgTo inquire5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire1mL*10mM (DMSO)To inquire10-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Formula:C43H51NO14Purity:98%Color and Shape:SolidMolecular weight:805.874ML 2-23
ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].Formula:C47H53BrCl2N10O7SPurity:98%Color and Shape:SolidMolecular weight:1052.86Protein Kinase C (19-36)
CAS:Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.Formula:C93H159N35O24Purity:98%Color and Shape:SolidMolecular weight:2151.48SNIPER(ABL)-019
SNIPER(ABL)-019, a compound that links Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, exhibiting aFormula:C60H77ClN12O9SPurity:98%Color and Shape:SolidMolecular weight:1177.85SNIPER(ABL)-044
SNIPER(ABL)-044, a compound that links HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving aFormula:C51H64F3N9O8SPurity:98%Color and Shape:SolidMolecular weight:1020.17Foxy-5 acetate
Foxy-5 acetate: Wnt 5A agonist, inhibits cancer cell migration/invasion, boosts calcium signaling, doesn't activate β-catenin.Formula:C28H46N6O14S2Purity:98%Color and Shape:SolidMolecular weight:754.83CCT 031374 hydrobromide
CAS:CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.Formula:C23H20BrN3OPurity:99.50%Color and Shape:Yellow SolidMolecular weight:434.33Ref: TM-T21685
1mg35.00€5mg67.00€1mL*10mM (DMSO)82.00€10mg100.00€25mg197.00€50mg313.00€100mg447.00€200mg587.00€Chaetominine
CAS:Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.Formula:C22H18N4O4Color and Shape:SolidMolecular weight:402.40Risuteganib
CAS:Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.Formula:C22H39N9O11SPurity:98%Color and Shape:SolidMolecular weight:637.66Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Color and Shape:Odour SolidHSDVHK-NH2
CAS:Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.Formula:C30H48N12O9Purity:98%Color and Shape:SolidMolecular weight:720.78Arg-Gly-Glu-Ser
CAS:Arg-Gly-Glu-Ser is a RGD related peptide that is a control for the RGDS activity of fibrinogen binding to activated platelets.Formula:C16H29N7O8Purity:98%Color and Shape:SolidMolecular weight:447.44TAT-PAK18 inhibitory peptide
TAT-PAK18 inhibitory peptide is a cell-permeable PAK inhibitor peptide. It is capable of reducing F-actin clusters and interfering with Shank3 knockdown effects.Formula:C146H254N58O37Color and Shape:SolidMolecular weight:3411.97769Monomethyl auristatin E intermediate-8
MonomethylauristatinE intermediate-8 is an intermediate compound in the synthesis of MonomethylauristatinE. MonomethylauristatinE (MMAE) acts as a microtubule/tubulin inhibitor with anticancer properties. It is widely utilized as the cytotoxic component in antibody-drug conjugates (ADCs).Formula:C20H31NO5Color and Shape:SolidMolecular weight:365.22022Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cellFormula:C17H13ClN6OSColor and Shape:SolidMolecular weight:384.84AB-3PRGD2
CAS:AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.Formula:C137H215IN30O45SColor and Shape:SolidMolecular weight:3161.32Combretastatin A-1 phosphate tetrasodium
CAS:OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Formula:C18H18Na4O12P2Color and Shape:SolidMolecular weight:580.2411H-Benzo[a]carbazole
CAS:11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.Formula:C16H11NPurity:99.14%Color and Shape:SolidMolecular weight:217.27Gamitrinib TPP
CAS:Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.Formula:C52H65N3O8PPurity:98%Color and Shape:SolidMolecular weight:891.078MS21
CAS:MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.Formula:C58H79ClN12O6SColor and Shape:SolidMolecular weight:1107.86SNIPER(ABL)-013
SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 ofFormula:C42H52F3N7O8Purity:98%Color and Shape:SolidMolecular weight:839.9MAL3-101
CAS:MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).Formula:C54H66N4O10Color and Shape:SolidMolecular weight:931.12MS170
CAS:MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.Formula:C45H56ClN9O7Color and Shape:SolidMolecular weight:870.45Ac-MRGDH-NH2
Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.Formula:C25H41N11O8SColor and Shape:SolidMolecular weight:655.727Neuropeptide DF2
CAS:Neuropeptide DF2 is an FMRFamide-related neuropeptide from crayfish.Formula:C44H67N15O10Purity:98%Color and Shape:SolidMolecular weight:966.1Dentonin TFA
Dentonin TFA (AC-100 TFA) is a short peptide fragment derived from MEPE. It enhances osteogenesis by promoting the adhesion of osteoprogenitor cells and supports the survival of immature adherent cells. Dentonin TFA does not have a significant effect on mature osteoblasts and can be utilized in studies of phosphate homeostasis and bone metabolism.Formula:C109H161F3N30O44Molecular weight:2651.1235st-Ht31
CAS:Ht-31 stearate: Blocks RII subunits of PKA & AKAP interaction in cells; cell-permeable.Formula:C129H217N29O39Purity:98%Color and Shape:SolidMolecular weight:2798.27hAChE-IN-1
hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.Formula:C22H24N4OColor and Shape:SolidMolecular weight:360.45Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purity:99.57%Color and Shape:SolidMolecular weight:447.48Variabilin
CAS:Variabilin is a natural product that can be used as a reference standard. The CAS number of Variabilin is 3187-52-8.Formula:C17H16O5Color and Shape:SolidMolecular weight:300.31Microtubule-associated protein tau (26-44)
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.Formula:C83H127N25O34SPurity:98%Color and Shape:SolidMolecular weight:2051.11Wortmannin-Rapamycin Conjugate
CAS:Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer.Formula:C88H131N3O23Color and Shape:SolidMolecular weight:1599.0141-Oleoyl-2-acetyl-sn-glycerol
CAS:1-Oleoyl-2-acetyl-sn-glycerol (1-oleoyl-2-acetyl-glycerol) is a PKC activator that induces superoxide production.Formula:C23H42O5Color and Shape:Transparent LiquidMolecular weight:398.58Tubulin polymerization-IN-62
Tubulin polymerization-IN-62 (Compound 14b) is a microtubule polymerization inhibitor (IC50 of 7.5 μM) that also functions as a degradation agent for α-/β-tubulin. This compound suppresses the proliferation of cancer cells MCF-7, A549, and HCT-116 with IC50 values of 32, 60, and 29 nM, respectively. It induces G2/M phase cell cycle arrest and inhibits the migration of MCF-7 cells. In a 4T1 syngeneic mouse model, Tubulin polymerization-IN-62 demonstrates antitumor efficacy with a tumor growth inhibition rate (TGI) of 74.27%.Formula:C37H44N4O4Color and Shape:SolidMolecular weight:608.33626
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