Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Found 1537 products for "Cytoskeletal Signaling".
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
TAT-Gap19
CAS:Cx43 blocker, IC50 ~7μM; doesn't affect gap junctions/Panx1. TAT motif enhances effect; works in vivo, brain-penetrant.Formula:C119H212N46O26Purity:98%Color and Shape:SolidMolecular weight:2703.28INY-03-041 trihydrochloride
INY-03-041 trihydrochloride: potent, selective PROTAC AKT degrader; combines Ipatasertib and Lenalidomide; IC50s: AKT1 (2.0 nM), AKT2 (6.8 nM), AKT3 (3.5 nM).Formula:C44H59Cl4N7O5Color and Shape:SolidMolecular weight:907.8PDS-0330
CAS:PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.Formula:C25H17N3O2SPurity:98.81%Color and Shape:Yellow SolidMolecular weight:423.49Bisindolylmaleimide III
CAS:Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Formula:C23H20N4O2Purity:97.2%Color and Shape:SolidMolecular weight:384.43P259
P259 is a Drp1-Mff inhibitor that selectively impedes the interaction between Drp1 and Mff, thereby differentiating physiological fission from pathological fission. It leads to mitochondrial elongation and impairs mitochondrial function and motility. P259 reduces ATP levels in the brain, alters mitochondrial structure, induces behavioral defects in wild-type mice, and shortens the lifespan of Huntington's disease (HD) model mice.Color and Shape:Odour Solidαvβ6-BP
αvβ6-BP is a selective αvβ6-binding peptide, useful for research in molecular imaging.Formula:C93H164N34O27Molecular weight:2189.25052AD57
CAS:AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.Formula:C22H20F3N7OPurity:99.05%Color and Shape:SolidMolecular weight:455.44Ref: TM-T22552L
2mg38.00€5mg86.00€1mL*10mM (DMSO)88.00€10mg145.00€25mg236.00€50mg339.00€100mg460.00€200mg622.00€Sangivamycin
CAS:Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.Formula:C12H15N5O5Purity:99.85%Color and Shape:SolidMolecular weight:309.28Ref: TM-T9605
1mg119.00€5mg260.00€1mL*10mM (DMSO)341.00€10mg394.00€25mg640.00€50mg893.00€100mg1,198.00€TNIK-IN-7
CAS:TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cellsFormula:C23H22N4O2Purity:99.97%Color and Shape:SolidMolecular weight:386.45Microtubule inhibitor 11
Microtubule inhibitor 11 (compound 33) is a tubulin inhibitor with a mechanism of action similar to that of colchicine. It is utilized in cancer-related research.Formula:C28H27N3O4Color and Shape:SolidMolecular weight:469.20016SIAIS178
CAS:SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).Formula:C50H62ClN11O6S2Purity:98.07%Color and Shape:SolidMolecular weight:1012.68Ref: TM-T12907
1mg152.00€5mg356.00€1mL*10mM (DMSO)393.00€10mg485.00€25mg888.00€50mg1,431.00€100mg2,052.00€200mg2,673.00€DPH
CAS:DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.Formula:C18H13FN4O2Purity:99.65%Color and Shape:SolidMolecular weight:336.32Kinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Color and Shape:Odour SolidRef: TM-L1600
1mgTo inquire10μL*10mM (DMSO)To inquire20μL*10mM (DMSO)To inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireSNIPER(ABL)-050
SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.Formula:C68H84N12O9Purity:98%Color and Shape:SolidMolecular weight:1213.47RA-PR058
RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.Formula:C11H15ClF3N3OColor and Shape:SolidMolecular weight:297.7ZIP
CAS:Novel inhibitor for PKMζ, halts synaptic potentiation and reverses LTP with IC50 of 1-2.5 μM, erasing spatial memory.Formula:C90H154N30O17Purity:98%Color and Shape:SolidMolecular weight:1928.4p5 Ligand for Dnak and DnaJ
CAS:P5 is a nonapeptide ligand for DnaK/DnaJ, mimicking the key sites of mitochondrial aspartate aminotransferase presequence.Formula:C44H81N15O11SPurity:98%Color and Shape:SolidMolecular weight:1028.27JG-258
CAS:JG-258 is an inactive negative control for Hsp70 inhibitors [1] .Formula:C20H22ClN3OS3Color and Shape:SolidMolecular weight:452.06Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Formula:C16H13ClN6SColor and Shape:SolidMolecular weight:356.83Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].Formula:C35H39N9O3Color and Shape:SolidMolecular weight:633.74
