Deuterated Compounds

Applications Cyclopropyl Methyl Ketone-d8 (CAS# 1219799-33-3) is a useful isotopically labeled research compound.

Applications N-Pentadecane (D32, 98%) (cas# 36340-20-2) is a useful research chemical.

Applications Benzimidazole-4,5,6,7-d4 (CAS# 64531-29-9) is a useful isotopically labeled research compound.

Applications Nicotinic Acid Riboside-d4 Methyl Ester Triflate O-Acetate is an intermediate used in the synthesis of Nicotinic Acid Riboside-d4 Methyl Ester Triflate (N429407), which is the labelled analogue of an effective agent for increasing nicotinamide adenine dinucleotide (NAD) concentrations in mammalian cells.
References Belenky, P. et al.; J. Biol. Chem. 284, 158 (2009); Yang, T. et al.: J. Med. Chem., 50, 6458 (2007);

Applications (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide-D3 is the deuterated form of (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide (C363865), which is used in the synthesis of Vildagliptin (V305000), an oral anti-diabetic drug, and its impurities (H971380) (Impurity A).
References Kumar, N., et al.: J. Pharmaceut. Biomed.,119, 114 (2016); Deng, Y., et al.: Lett. Org. Chem., 11, 780 (2014);

Applications Bromocyclopropane-d5 is labelled bromocyclopropane (B682760) which is used as a reagent to synthesize substituted (carboxycyclopropyl)glycines as potent and selective group II metabotropic glutamate receptor antagonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ornstein, P., et al.: J. Med. Chem., 41, 358 (1998)

Applications 4,4'-Dihydroxybiphenyl-d8 (rings-d8) (CAS# 612480-60-1) is a useful isotopically labeled research compound.

Applications (S)-3-Aminopiperidin-2-one-D6 is a labelled analogue of (S)-3-Aminopiperidin-2-one (A627940). (S)-3-Aminopiperidin-2-one, is an building block , used in the synthesis of various pharmaceutical compounds. It is an intermediate in the synthesis of calpinactam derivatives, possessing antimycobacterial activity.
References Kenichiro, N., et al.: Bioorg. Med. Chem. Lett., 22, 7739 (2012);

Applications Potassium Octadecanoate-2,2-d2 (CAS# 352438-86-9) is a useful isotopically labeled research compound.

Applications 1,4-Dibromobutane-1,1,4,4-d4 (CAS# 36684-45-4) is a useful isotopically labeled research compound.

Applications 3-Hydroxyphenylacetic Acid-d4 is the deuterated isotope of 3-Hydroxyphenylacetic Acid (H949070).

Applications 1,10-Dibromodecane-d20 (CAS# 150017-88-2) is a useful isotopically labeled research compound.

Applications A deuterated alcohol used in the study of lignite liquefaction.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kuznetov, P.N. et al.: Fuel, 70, 559 (1991);

Applications (R)-Telaprevir-d4 is the labeled analog of (R)-Telaprevir, an enantiomer of Telaprevir (T015650). Telaprevir is an known inhibitor of the hepatitis C virus NS3-4A protease. It is a COVID19-related research product.
References Francois, J., et al.: J. Medn. Chem., 52. 7993 (2009); Kieffer, T., et al.: Hepatology, 46, 631 (2007), Zhou, Y., et al.: Antimicrob. Agents Chemother., 52, 110 (2008), Hezode, C., et al.: N. Engl. J. Med., 360, 1839 (2009);

Applications Bis(3-methyl-2-pentyl) Phthalate-d4, is the labeled analogue of Bis(3-methyl-2-pentyl) Phthalate (B486015), used as a plasticizer to impart softness and flexibility to PVC products.
References Pierson, J. F., et al.: Angewandte Makromolekulare Chemie, 38, 167 (1979); Kaya, T., et al.: Chem. Res. Toxic., 19 (8), 999 (2006); Matter, H., et al.: Bioorg. Med. Chem., 20 (18), 5352 (2012);

Applications 1,2-Ethane-d4-dithiol (CAS# 100189-81-9) is a useful isotopically labeled research compound.

Applications n-Heptyl-1-d1 Alcohol (CAS# 38007-42-0) is a useful isotopically labeled research compound.

Applications Perfluorododecanoic Acid-13C is labeled P286255 which is fluorinated pollutant found in wastewater and industrial runoff. Potential risk factor for coronary heart disease.
References Mattsson, K. et al.: Env. Res., 142, 148 (2015); Yuan, G. et al.: Env. Sci. Tech., 50, 942 (2016);

Applications n-Hexadecyl-1,1,2,2-d4 Hexadecanoate-16,16,16-d3 (CAS# 1398066-15-3) is a useful isotopically labeled research compound.

Applications A labelled metabolite of Colchicine (C640000). Has shown anti-tumor activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Martinez, M. et al.: J. Appl. Toxicol., 15, 49 (1995); De Vincenzo, R. et al.: Oncol. Res., 11, 145(1999); Das, D. et al.: Biochim. Biophys. Acta., 1502, 351 (2000); Wagner, B. et al.: J. Biol. Chem., 275, 22461(2000);

Applications Formamide-1-d1 (CAS# 35692-88-7) is a useful isotopically labeled research compound.

Applications α-Cholesterol-d6 is labelled α-Cholesterol which is a stereoisomer of Cholesterol (C432501), a major component of all biological membranes and the principal sterol of the higher animals.
References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),

Applications 1,2-Dichloroethylene (1,2-D2, 98%) Cis/Trans Mix (cas# 15075-90-8) is a useful research chemical.
Chemical Name: 1,2-Dichloroethylene (1,2-D2, 98%) Cis/Trans Mix (cas# 15075-90-8) is a useful research chemical.

Applications 3-(Anilinosulfonyl)-benzenecarboxylic Acid -D5 is the labeled compound of 3-(Anilinosulfonyl)-benzenecarboxylic Acid (3-ASBA) (A157600). 3-(Anilinosulfonyl)-benzenecarboxylic Acid (3-ASBA) is used in preparation of N-hydroxy[(phenylsulfamoyl)phenyl]acrylamides useful as histone deacetylase inhibitors for the treatment of cancer.
References Yihan, W., et al.: Patents, (2017),

Applications Methyl Methacrylate-3,3-d2 (CAS# 55063-97-3) is a useful isotopically labeled research compound.

Applications Aclonifen-d5, is the labeled analogue of Aclonifen, which is used as a pesticide and herbicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Laini, A., et al.: Sci. Total Environ., 438, 312 (2012); Fantke, P., et al.: Enviorn. Int., 49, 9 (2012);

Applications Dimethyl Hexanedioate-2,2,5,5-d4 (CAS# 76785-05-2) is a useful isotopically labeled research compound.

Applications N-Octanoylglycine-2,2-d2 (CAS# 1219805-51-2) is a useful isotopically labeled research compound.

Applications 2,2',3,5',6-Pentachlorobiphenyl-13C12 is the labeled analogue of 2,2',3,5',6-Pentachlorobiphenyl (P237935), an environmental neurotoxicant that promotes synaptogenesis through ryanodine receptor-dependent miR132 upregulation.
References Lesiak, A., et. al.: J. Neurosci., 34, 717 (2014)

Applications 3-Bromoaniline-d4 (cas# 81395-17-7) is a compound useful in organic synthesis.