Deuterated Compounds

Applications N-Tris(hydroxymethyl)methyl-2-aminoethanesulfonic Acid-d15 (CAS# 1219794-63-4) is a useful isotopically labeled research compound.

Applications N,N-Dibutyl-4,6-dichloro-1,3,5-triazin-2-amine-d4 is an intermediate used in the synthesis of 6-(Dibutylamino)-1,3,5-triazine-2,4-dithiol-d4 (D462764), which is a labelled form of 6-(Dibutylamino)-1,3,5-triazine-2,4-dithiol (D462763), which is a compound capable of electrochemical polymerization on magnesium alloy plates.
References Mori, K.; et al.: Materials Science Forum, 350, 223 (2000).

Applications 2,4'-Dibromoacetophenone-2-13C (CAS# 335081-05-5) is a useful isotopically labeled research compound.

Applications 1-Bromoeicosane-20,20,20-d3 (CAS# 202480-72-6) is a useful isotopically labeled research compound.

Applications 2-Acetyl-3,4,5,6-tetrahydropyridine-d4 Hydrochloride, is the labeled analogue of 2-Acetyl-3,4,5,6-tetrahydropyridine Hydrochloride (A188500), the most important bread flavor component.
References Buttery, R.G., et al.: J. Agric. Food Chem., 43, 1878 (1995),

Applications Labelled Malic Acid. The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
References Rindi, G., et al.: Biochem. J., 80, 214 (1961), Wolfgang, M., et al.: J. Biol. Chem., 281, 37265 (2006), Navarro, D., et al.: Metab. Brain Dis., 23, 115 (2008),

Applications 1-Bromoheptane-7,7,7-d3 (CAS# 344253-18-5) is a useful isotopically labeled research compound.

Applications 4-Chlorophenylamine-13C6 (cas# 89059-39-2) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Propiophenone-d5 is the labeled analogue of Propiophenone (P827900), an aryl ketone used in the preparation of pharmaceutical and organic compounds. Propiophenone is used in perfumes as well as in the preparation of neurochemical compounds such as ephedrines.
References Edkins, R.P. et al.: Quart. J. Pharm. Pharmacol., 9, 203 (1936); Sun, T.-Q. et al.: Zhong. Yiy. Gong. Zaz., 31, 534 (2000); Cherkaoui, H. et al.: Tetrahedron, 57, 2379 (2001)

Applications Mieshuan-d4 is labelled Mieshuan (M343800) which is a pesticide. It is effective against house and wild rodents, including rats and mice.
References Teng, T., et al.: Zhonghua Yufang Yixue Zazhi, 13, 220 (1979); Deng, Z.: Chinese J. Preventive Medicine, 13, 220 (1979)

Applications 2-(3,4-Dihydroxyphenyl)ethyl-1-13C-amine HCl (CAS# 335081-04-4) is a useful isotopically labeled research compound.

Applications (±)-Prasugrel-d3 (acetate-d3) (CAS# 1127253-02-4) is a useful isotopically labeled research compound. This compound can be used for treating percutaneous coronary intervention.
References Czarnik, A., U.S. Pat. Appl. Publ., 9,(2009);

Applications 2-(3,4-Dihydroxyphenyl)ethyl-1,1-d2-amine HCl (CAS# 83008-33-7) is a useful isotopically labeled research compound.

Applications 2-Fluoroaniline-4,6-d2,ND2 (CAS# 1219804-77-9) is a useful isotopically labeled research compound.

Applications 2-Ethyl-m-xylene-d5, is the labeled analogue of 2-Ethyl-m-xylene (E932360), one of the components thermocontact pyrolysis tars. It has been also found to be one of the volatile organic emissions from Motor Vehicles, that might have impact on ozone production.
References Koretskaya, N. A., Neftepererabotka i Neftekhimiya, 10, 44 (1978); Gentner, D. R., et al.: Environ. Sci. Tech., 47, 11837 (2013);

Applications 4-Hydroxychlorpropham-d7 is an intermediate in the synthesis of 4-Hydroxychlorpropham-d7 Sulfate Sodium Salt (H825077). 4-Hydroxychlorpropham-d7 Sulfate Sodium Salt is derived from Isopropanol-d7 (I822752), which is a deuterated alcohol used in the study of lignite liquefaction. 4-Hydroxychlorpropham-d7 is also the labelled analogue of 4-Hydroxychlorpropham (H825078). 4-Hydroxychlorpropham is an intermediate in synthesizing 4-Hydroxychlorpropham Sulfate Sodium Salt (H825075), which is a chemical herbicide used in the protection of crops. It also maintains the ability to induce mitochondrial dysfunction in rat hepatocytes.
References Kuznetov, P.N. et al.: Fuel, 70, 559 (1991); EPA.: Fed. Reg., 72, 37646 (2007); Nakagawa, Y. et al.: Toxicol., 200, 123 (2004)

Applications 1-Bromoheptane-d15 (CAS# 98195-42-7) is a useful isotopically labeled research compound.

Stability Hygroscopic
Applications Isovaleryl L-Carnitine-d9 Chloride is labelled Isovaleryl L-Carnitine Chloride (I917580) which is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.
References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)

Applications 2-Oxopiperazine-3,3,5,5,6,6-d6 (CAS# 1219803-71-0) is a useful isotopically labeled research compound.

Applications Benzene-13C6 ,is isotopically labelled benzene, an organic compound that is a natural constituent of crude oil and one of the most basic petrochemicals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Feng, Z.X.. et al.: J. Phys. Chem. Lett. 4, 285 (2013); Pilling. M., et al.: Chem. Eng. Prog., 108, 32 (2012);

Applications Propargyl Alcohol-13C3 is labelled Propargyl Alcohol (P762550) which is used as a corrosion inhibitor, a metal complex solution, a solvent stabilizer and an electroplating brightener additive. It is also used as an intermediate in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, T., et al.: Res. Chem. Interm. (2013); Choudhary, Y., et al.: SPE Product. Operat., 28, 268 (2013); Hed, Y., et al.: J. Mater. Chem. Mater. Bio. Med., 1, 6015 (2013)

Applications 3-(Azidomethyl)heptane-D5 is an intermediate in the synthesis of Alexidine-d10 Dihydrochloride (A525002), which has antibacterial, antiplaque properties against Streptococcus mutans, Actinomyces ciscosus, and Actinomyces naesludii.
References Coburn, R.A., et al.: J. Med. Chem., 21, 8, 829 (1978), Takayama, K., et al.: J. Biol. Chem., 269, 2241 (1994), Faure, P., et al.: Biochimie, 86, 411 (2004),

Applications Diethylamine-13C4 Hydrochloride is the labelled salt of Diethylamine (D443485).

Applications Methyl 2-Hydroxybenzoate-3,4,5,6-d4 (CAS# 1219802-12-6) is a useful isotopically labeled research compound.

Applications 2-[2-(Methyl-d3-thio)ethyl-1,1,2,2-d4]-1H-isoindole-1,3(2H)-dione is an intermediate used in the synthesis of Lapatinib-d7 Dihydrochloride (L175807), which is a labeled Lapatinib (L175800), a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic;Also, it is used in the preparation of 4-Aminoquinazolines as EGFR and HER-2 inhibitors.
References Kim, T.E., et al.: Drugs, 6, 886 (2003); Wood, E.R., et al.: Cancer Res., 64, 6652 (2004); Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005); Tung, R.: PCT Int. Appl. (2008), WO 2008024439 A2 20080228

Applications 2-Hydroxypyridine-N-oxide-d5 is the labelled analogue of 2-Hydroxypyridine-N-oxide (H953633), a reactant that is useful along wtih (S)-1-phenylethylamine and EDC·HCl for the synthesis of AZD8186, a potent and selective Inhibitor of PI3Kβ and PI3Kδ.
References B. Barlaam., et al.: J. Med. Chem., 58, 943-62 (2015);