Organic Halides

<p>Applications Di-tert-butyldichlorosilane (cas# 18395-90-9) is a useful research chemical.<br></p>

<p>Applications 3-Aminobenzamidine Dihydrochloride is a reactant that has been used in the synthesis of N-phenylamidines as selective inhibitors of human neuronal nitric oxide synthase.<br>References Collins, J.L., et. al.: J. Med. Chem., 41, 2858 (1998)<br></p>

<p>Applications 2-Iodoxybenzoic Acid is used in the oxidation of alcohols in organic synthesis. It is also frequently used in the preparation of Dess-Martin periodinane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Frigerio, M. et al.: J. Org. Chem., 60, 7272 (1995); Ireland, R. et al.: J. Org. Chem., 58, 2899 (1993);<br></p>

<p>Applications 4-tert-Butyl-1,2-bis(chloromethyl)benzene is used as a reactant in the preparation of dihydronaphthalenes/naphthalenes via cobalt-catalyzed formal [4+2] cycloaddition of α,α'-dichloro-ortho-xylenes with alkynes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Komeyama, K., et al.: Angew. Chem. Int. Ed., 53, 11325 (2014);<br></p>

<p>Applications 2-Chloroethylamine Hydrochloride is used as a reagent in the synthesis of 6-desfluoroquinolones as potential anti-HIV drugs. Also used as a reagent in the synthesis of ellipticine derivatives as anticancer agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sancineto, L., et al.: Bioorg. Med. Chem., 22, 4658 (2014); Mori, R., et al.: Eur. J. Med. Chem., 82, 16 (2014)<br></p>

<p>Applications Chlorthiamid<br></p>

<p>Applications 9-(2-Chloro-ethyl)-9H-purin-6-ylamine (cas# 19255-48-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,2,4-Tribromobenzene is a compound commonly used in organic synthesis reactions. 1,2,4-Tribromobenzene is hepatotoxic to rats, and is also toxic to humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dodd, D., et al.: Int. J. Toxicol., 31, 250 (2012); Szymanska, J.: Arch Toxicol., 72, 97 (1998)<br></p>

<p>Stability Moisture Sensitive<br>Applications 3,5-Dinitrobenzoyl Chloride was used as a derivatization agent for high performance liquid chromatographic analysis of several compounds including polyamines and acteylated derivatives, taurine and hypotaurine and biogenic amines in fermented foods. It was also used in the synthesis of several organic compounds including that of a novel starch derivative which has adsorption property for creatinine and may therefore be useful in treatment of renal failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kirschbaum, J., et al.: J. Chromatogr A., 881, 517 (2000); Wongyai, S., et al.: Biomed. Chromatogr., 2, 254 (1988); Masuoka, N., et al.: J. Chromatogr B., 660, 31 (1994); Jiu-gao, Y., et al.: Acta Pharm. Sin., 38, 191 (2003);<br></p>

<p>Applications Methoxylamine is a methoxime derivative used as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Herold, D.A. et al.: Prostaglandins, 33, 599 (1987);<br></p>

<p>Applications Iodine Monobromide is an electrophile used in preparation of polyketide structural units via eletrophile-induced methoxy transfer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, K., et al.: Org. Lett., 8, 5393 (2006).<br></p>

<p>Applications trans-3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is a reagent used in the synthesis of indanyl insecticides.<br></p>

<p>Applications Ammonium Chloride is used as a main component and source of nitrogen in fertilizer.<br>References Crill, P. et al.: Soil Biol. Biochem., 26, 1331 (1994); Zaman, M. et al.: Biol. Fert. Soils, 29, 178 (1999);<br></p>

<p>Applications Tetrachlorohydroquinone is a chlorinated hydroquinone compound used as an analytical standard.<br></p>

<p>Stability Hygroscopic<br>Applications 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride (cas# 76833-47-1) is a useful research chemical.<br></p>

<p>Applications 2-Chloro-1,3,2-dioxaphospholane-2-oxide is used in the synthesis of α-naphthylphosphorylcholine as a method to detect phospholipase C activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Durban, M. et al.: Eur. J. Lipid. Sci. Tech., 105, 633 (2003);<br></p>

<p>Applications 1-(2,3-Dimethylphenyl)ethyl Chloride is an impurity of Medetomidine (M203250), an α2-Adrenergic agonist. Sedative; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),<br></p>

<p>Applications 1-[4-(2-Chloroethoxy)phenyl]-2-phenylethanone (cas# 19561-95-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Amino-5-chlorobenzenesulfonic Acid can be used as reactant/reagent in determination of the dissociation constants of some newly synthesized arylhydrazones of indane-​1,​3-​dione.<br>References Mahmudov, K. T.: Azerbaidzhanskii Khimicheskii Zhurnal, 4, 92 (2011)<br></p>

<p>Applications 1-(Bromomethyl)pyrene (cas# 2595-90-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Tryptamine hydrochloride (cas# 343-94-2) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Lauroyl Chloride (cas# 112-16-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light Sensitive<br>Applications 1,2-Dichloroethylene (Mixture of cis and trans) is a chlorinated solvent used in organic synthesis. Environmental pollutant found in river ecosystems contributing to habitat degradation.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schaefer, R. et al.: Freshwater Biol., 61, 2116 (2016);<br></p>

<p>Applications 2-Chloro-4,5-dinitro-toluene (cas# 56136-79-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Bromonitromethane is used in the preparaton of [2,3-d]pyrimidines as inhibitors of Lck which can be used in the treatment of diseases where T-cell proliferation is unwanted. It is also used in the synthesis of isoxazoline N-oxides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References DiMauro, E. et al.: Bioorg. Med. Chem. 17, 2305 (2007); Kunetsky, R. et al.: Org. Lett., 5, 4907 (2003);<br></p>

<p>Applications 2,2-Dibromopropanoic Acid is a disinfection byproduct (DBP) produced by disinfection of drinking water rich in bromide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Richardson, S.D., et al.: Environ. Sci. Technol, 37, 3782-3793 (2003);<br></p>

<p>Stability Volatile<br>Applications Pentafluoropropionic acid (Perfluoropropionic acid) was used in the analysis of gentamicin with Gemini column by liquid chromatographic (LC) methods. It was also used to prepare [(R)-(amino)(oxo)(fluorophenyl)butyl]tetrahydro(fluoroethyl)-1,2,4-triazolo[4,3-a]pyrazine using (fluoro)propanoic acid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Manyanga, V., et al.: J. Pharm. Biomed. Analysis, 45, 257 (2007); Kim, D., et al.: J. Med. Chem., 48, 141 (2005)<br></p>

<p>Applications 4-Chloro-1,1’-biphenyl (cas# 2051-62-9) is a compound useful in organic synthesis.<br></p>

<p>Applications A reagent used in the preparation of hepatitis C virus NS3 protease inhibitors and PMPA prodrugs with antiretroviral activity.<br>References Sheng, X. et al.: Bioorg, Med. Chem. Lett., 169, 3453 (2009); Arimilli, M.N. et al.: Antiviral Chem. Chemother., 8, 557 (1997);<br></p>

<p>Applications 7H-Dodecafluoroheptanoic Acid is a derivative of Heptanoic Acid (H998455) which can be used as an organic building blocks for the synthesis of variety of chemical compounds. Heptanoic Acid is used in the synthesis of 17-epi-Testosterone Enanthate (T155095). It is used in the preparation of esters, such as ethyl heptanoate, which are used in fragrances and as artificial flavors. It is also one of many additives in cigarettes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anneken, D. et al.: Fatty Acids, Ullmann's Encyclopedia of Industrial Chemistry (2006); Wudy, S., et al.: Steroids, 66, 759 (2001); Kootstra, P., et al.: Anal. Chim. Acta., 586, 82 (2007); Sten, T., et al.: Drug Metab. Dispos., 37, 417 (2009)<br></p>

<p>Applications 3-Aminophthalic acid hydrochloride (cas# 6946-22-1) is a useful research chemical.<br></p>

<p>Applications 1-Bromohexane is a very useful synthetic intermediate for pharmaceuticals and organic chemicals. It can be used to react with Mg to prepare Grignard reagents which play an important role in formation of carbon-carbon bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tamura, M., et al.: Synth., 6, 303 (1971); Asami, M., et al.: Chem. Lett., 8, 1221 (1985); Akiba, K., et al.: Tetrahedr. Lett., 23, 3935 (1982)<br></p>

<p>Applications 1,3-Bis(bromomethyl)benzene is a reagent used in the synthesis of germanosilicates to construct large pore zeolites. As well use to synthesize 2,4,5-triethylimidazolium scaffolds in photoactive anthracene rings.<br> E0<br>References Sabater, P. et al.: J. Org. Chem., 81, 3790 (2016); Boal, B. et al.: Chem. Mat., 28, 2158 (2016);<br></p>

<p>Stability Light Sensitive<br>Applications Dibromoacetonitrile is a carcinogenic nitrogenous disinfection byproduct. Dibromoacetonitrile in drinking water was linked to oral cavity cancer in rats and forestomach cancer in mice. In addition, Dibromoacetonitrile may cause oxidative damage in rat brain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, Z., et al.: Chem. Eng. J. 306, 1180 (2016); Krasner, S. W., et al.: Environ. Sci. Technol. 50, 9583 (2016); Natl Toxicol Program Tech Rep Ser. 544, 1 (2010); Klattisaksiri, P., et al.: Water Res 98, 160 (2016); Sayed, R. H., et al.: Environ Toxicol Pharmacol. 34, 849 (2012)<br></p>

<p>Applications p-Toluoyl chloride is an aromatic compound used as a reagent to synthesize (+)-Yashabushitriol, a plant metabolite that is naturally found in the male flowers of Alnus sieboldiana matsum. p-Toluoyl chloride is also used as a reagent to prepare derivatives of Desloratadine (D290250). Desloratadine is a selective H1-receptor antagonist that has anti-inflammatory effects and is used to treat patients with allergic rhinitis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Berger, W.. et al.: Ann. All. Asth. Immun., 89, 485 (2002); Fang, Z., et al.: Tetrahedron Lett., 54, 6834 (2013); Feldman, K. &amp; Simpson, R.: Tetrahedron Lett., 30, 6985 (1989); Mu, S., et al.: Chin. Chem. Lett., 24, 531 (2013)<br></p>

<p>Applications Bromothalonil can be used in biological study of comparison and validation of an in vitro skin sensitization strategy using a data set of 33 chemical references.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br>References Clouet, E., et al.: Toxicology In Vitro, (2017)<br></p>

<p>Stability Light and Temperature sensitive<br>Applications PFPA-silane is a functionalized perfluorophenyl azides for covalent immobilization of ultrathin polymer films.<br>References Mosbach, K., et al.: Biotechnology, 14, 163 (1996), Keren, K., et al.: Science, 297, 72 (2002), Lidstrom, M., et al.: Nature Rev. Microbiol., 1, 158 (2003),<br></p>

<p>Stability Light Sensitive<br>Applications 2-Bromopropionic Acid Benzyl Ester (cas# 3017-53-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>

<p>Applications 1H,1H,2H-Perfluoro-1-decene (cas# 21652-58-4) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Diphenyltin Dichloride belongs to a class of organotin compounds that are commonly used as pesticides, fungicides, and plastic additives. It is an environmental pollutant with potential antitumor activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Khosa, R.L. et al.: Sci. Cult., 35, 637 (1969); Hamasaki, T. et al.: Mutat. Res. Gen. Toxicol. Test., 300, 265 (1993); Peng, J.: Yaox. Xueb., 29, 406 (1994)<br></p>

<p>Applications 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]-ethanol, is used in the preparation of hydroxy(aminomethyl)pyridine derivatives.<br>References Elworthy, T.R., et al.: J. Med. Chem., 40, 2674 (1997)<br></p>

<p>Applications 3-Chloropropionic Acid (cas# 107-94-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications Aniline Hydrochloride is used in the making of new azo pyridone dyes for polyester fabrics and in the microwave-assisted preparation of arylazoaminopyrazoles as disperse dyes for textile printing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Khattab, T. A., et al.: Z. Anorg. Allg. Chem., 642, 766 (2016); Al-Etaibi, A., et al.: Eur. J. Chem., 5, 321 (2014)<br></p>

<p>Applications cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantantane Chloride is a quaternary ammonium salt used as a preservative in many cosmetics and industrial substances.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marouchoc, S.: Cosm. Sci. Technol. Series, 1, 143 (1984); Cheng, J., et al.: J. Toxicol. Cutan. Ocul. Toxicol., 14, 287 (1995);<br></p>

<p>Applications An organotin compound of type MenSnCl3-n(CH2)mMe (n = 0-3, m = 0-7). The substituent effects of the SnMe3, SnMe2Cl, SnMeCl2, and SnCl3 groups on the C chemical shifts in the alkyl group were determined; SnMe3 causes a small upfield shift on the directly bonded C whereas other groups cause downfield shifts.<br>References Mitchell, T.N., et al.: Org. Magnetic Resonance, 8, 34 (1976),<br></p>

<p>Applications Ethenesulfonyl chloride is a useful reactant for the preparation of oral quinoline-based ALDH1A1 inhibitors as potential antitumor agents.<br>References Yang, SM., et al.: J. Med. Chem., 61, 4883-4903 (2018);<br></p>

<p>Applications 4-[(2-chloroacetyl)amino]benzoic acid (cas# 4596-39-8) is a useful research chemical.<br></p>

<p>Applications 4-Bromophenol is used as a reagent in Stille reactions.<br>References Littke, A.F. et al.: J. Am. Chem. Soc., 124, 6343 (2002);<br></p>

<p>Applications 1-Bromobenzene, is used as a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miyaura, N. et al.: Synth. Commun., 11, 513 (1981); Nahm, S. et al.: Tetra. Lett., 22, 3815 (1981);<br></p>

<p>Applications 6,8-Dichloro-octanoate is an Intermediate in the synthesis of α-Lipoic acid (L468750) and its derivatives.<br>References Zhang, S.J. et al: Bioorg. Medn. Chem. Letters., 20, 3078 (2010);<br></p>

<p>Applications An intermediate for the synthesis of antitumor drugs used in chemotherapy<br>References Foster, A.B., et al.: J. Med. Chem., 24, 1399 (1981), Sorsa, M., et al.: Mutat. Res. Genet. Toxicol., 204, 465 (1988),<br></p>

<p>Applications N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.<br>References Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)<br></p>

<p>Stability Hygroscopic<br>Applications Used as an intermediate in the industrial preparation of non-ionic X-ray contrast agents such as Iohexol (I729500), Ioversol (I737000), Ioxilan (I737500), Iopamidol (I735600).<br>References Rongved, P., et al.: Carbohydrate Res., 297, 325 (1997),<br></p>

<p>Applications Hydrazine Dihydrochloride (cas# 5341-61-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Chloropropanols have mutagenic and carcinogenic properties. The 3-monochloropropanol (3-MCPD) is the main chloropropanol found in hydrolyzates of vegetable protein (HVP) made by acid hydrolysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Crews, C., et al.: Food Addit. Contam., 18, 271 (2001), Hamlet, C., et al.: Food Addit. Contam., 19, 15 (2002), Weisshaar, R., et al.: Eur. J. Lipid Sci. Technol., 112, 158 (2010),<br></p>

<p>Applications 1-Amino-2,4-dibromo-anthraquinone is a useful compound to study the uPAR·uPA protein-protein interaction (PPI) involved in signaling and proteolytic events that lead to tumor invasion and metastasis. It is also used to evaluate potential renal toxicants based on a relationship between chemical-induced kidney weight gain and kidney histopathology in rats. 1-Amino-2,4-dibromo-anthraquinone is a reagent utilized in copper-catalyzed Ullmann condensation to synthesize anthraquinone derivatives as novel dyes.<br>References Malik, E. M., et al.: Dyes Pigm. 131, 33 (2016); Craig, E. A., et al.: J. Appl. Toxicol. 35, 729 (2015); Mani, T., et al.: Bioorg. Med. Chem 21, 2145 (2013)<br></p>

<p>Applications 2-bromo-6-chlorophenol (cas# 2040-88-2) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications 2-(2,4-Diaminophenoxy)ethanol Dihydrochloride<br></p>

<p>Applications 1-Decylamine Hydrochloride is used as a cationic surfactant with copper or cobalt. 1-Decylamine Hydrochloride has also been used in the preparation of lyotropic liquid crystals.<br>References Badawi, A.M., et. al.: J. Surfactants Deterg., 10, 243 (2007); Luk, Y., et. al.: Chem. Materials, 17, 4774 (2005)<br></p>

<p>Applications 4-Chloro-4'-fluorobutyrophenone (cas# 3874-54-2) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications A versatile phosphitylating agent for the phosphorylation of hydroxy amino acids and the preparation of protected phosphopeptides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liskamp, R.M.J., et al.: Recl. Trav. Chim. Pays-Bas, 109, 27 (1990)<br></p>

<p>Applications 2,3,3,3-Tetrafluoropropanoic Acid (cas# 359-49-9) is a useful research chemical.<br></p>

<p>Applications Dimethyldimyristylammonium Chloride is used as a surfactant.<br>References Cipiciani, A., et al.: Austr. J. Chem., 44, 1505 (1991); Hueck, H., et al.: Appl. Microbiol., 14, 308 (1966)<br></p>

<p>Impurity Adapalene USP Related Compound A<br>Applications Methyl 6-Bromo-2-napthoate (Adapalene USP Related Compound A) is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.<br>References Milanese, A. et al.: Bioorg. Chem., 9, 151 (2011);<br></p>

<p>Applications epi-5-Fluoro ADB is an analog of fluoronatied ADB-PINACA an analog of AKB48 in which the adamantyl group has been replaced with 1-amino-3,3-dimethyl-1-oxobutan-2-yl (ADB). epi-5-Fluoro ADB is a synthetic cannabinoid. Synthetic Cannabinoids<br>References Uchiyama, N., et al.: Forensic Toxicol., 30, 114 (2012)<br></p>

<p>Applications 1,3,5-TRIMETHYL-1,3,5-TRIS(3,3,3-TRIFLUOROPROPYL)CYCLOTRISILOXANE (cas# 2374-14-3) is a useful research chemical.<br></p>

<p>Applications 2,4,5-trichlorobenzoic acid (cas# 50-82-8) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications 3-Chlorocyclohexene (cas# 2441-97-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Fluorobiphenyl (cas# 321-60-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,2,2-trichloroethanol (TCE) is an active metabolite of Trichloroacetaldehyde monohydrate [chloral hydrate (CH)] (T774055), a sedative/hypnotic that increases cerebral blood flow (CBF).<br>References Parelkar, N., et al.: J. Pharma. Exper. Ther., 332, 803 (2010); Merdink, J., et al.: Toxicol, 245, 130 (2008)<br></p>

<p>Applications Used for preparation of substituted indazole amides as glucokinase activators.<br>References Perles, J., et al.: J. Mater. Chem., 14, 2683 (2004),<br></p>

<p>Stability Moisture Sensitive (Reactive)<br>Applications Iodotrimethylsilane is a reagent used for cleaving ethers, esters, carbamates, ketals and lactones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heck, M., et al.: Tetrahedron Lett., 35, 5445 (1994); Hiral, G., et al.: Biorg. Med. Chem. Lett., 14, 2647 (2004)<br></p>

<p>Applications Axitinib Iodo Tetrahydropyran is an analog of Axitinib (A794650). Axitinib (A794650) is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.<br>References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003);Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002); Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003);<br></p>

<p>Applications Reagent used in the synthesis of cyhalothric pesticides and fungicides.<br>References Sun, C., et al.: Bioorg. Med. Chem., 14, 8574 (2006),<br></p>

<p>Applications 2-Amino-3-(2-chlorobenzoyl)thiophene is a useful compound for the synthetic process of Brotizolam (B689280(M)), which is a hypnotic and a sedative.<br>References Du, D. P., et al.: Zhongguo Yaowu Huaxue Zazhi, 25, 280 (2015); Sato, T., et al.: J. Med. Chem., 51, 7705 (2008); Nishino, T., et al.: J. Pharmacol. Sci., 107, 349 (2008); Yamashiro, T., et al.: J. Clin. Pharm, Ther., 33, 273 (2008); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)<br></p>

<p>Applications 1,1-Dibromoethane is a useful reagent for setereoselective synthesis of (+)-phorboxazole A via Petasis-Ferrier rearrangement. It is also used for preparation of olefinic enol ether.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Smith, A., et al.: J. Am. Chem. Soc., 123, 10942 (2001); Fujimura, O, et al.: J. Org. Chem., 59, 4029 (1994);<br></p>

<p>Applications Iodosobenzene (cas# 536-80-1) is a useful research chemical.<br></p>

<p>Stability Not stable in Solution<br>Applications 1-Amino-1-deoxy-D-fructose HCl<br></p>

<p>Applications 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone is used in the synthesis of acid chloride phenylhydrazones in a broad-spectrum anthelmintic series.<br>References Rector, D. et al.: J. Med. Chem., 24, 532 (1981);<br></p>

<p>Applications 1-Bromo-2-octyne, is an intermediate in the synthesis of pinolenic acid. This compound is also used in preparation of substituted indoles though Rh-catalyzed amino-Claisen rearrangement.<br>References Saito, A., et al.: J. Org. Chem., 74, 1517 (2009)<br></p>

<p>Stability Volatile<br>Applications 2,2,3,3,4,4-Hexafluoro-1-butanol has been used in phase-​transfer catalysis as a reactant in the synthesis process of fluorinated allylic ethers and thio ethers.<br>References Boutevin, B., et al.: J. Fluorine. Chem., 35, 399-410 (1987).<br></p>

<p>Applications 3-Chlorobenzene-1,2-diamine<br></p>

<p>Applications 2,3,4,5,6-Pentabromophenol is used in the synthesis of alkyltrichlorosilane surface modifiers for biomedical applications. Also used in the synthesis of flame retardant polymers.<br>References Blaszykowski, C. et al.: Langmuir, 28, 2318 (2012); Alam, S. et al.: Ann. Tech. Conf. Soc. Plas. Engineers., 3, 2400 (2011);<br></p>

<p>Applications Glycerol kinase substrate specificity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Castro, C., et al.: Biochemistry, 7, 3213 (1968), Janssen, D., et al.: Eur. J. Biochem., 171, 67 (1988), Kurihara, T., et al.: J. Biochem., 117, 1317 (1995),<br></p>

<p>Applications Octafluorocyclopentene (cas# 559-40-0) is a useful research chemical.<br></p>

<p>Applications Chlorobenzene is a halogenated benzene used in chemical toxicity QSAR research for agricultural pollution.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fielden, M., et al.: Curr. Opin. Drug Discovery Dev., 9, 84 (2006), Jonker, M., et al.: Carcinogenesis, 30, 1805 (2009), Jennen, D., et al.: Toxicol. Sci., 115, 66 (2010),<br></p>

<p>Applications Magnesium Chloride Hexahydrate is used in magnesium replacement therapy for those deficient in magnesium. Effective anaesthetic for cephalopods.<br>References Iezhitsa, I. et al.: Nutr. Neurosci., 14, 10 (2011); Culloty, S. et al.: Aquaculture., 107, 249 (1992);<br></p>

<p>Applications 2,4'-Dichlorobenzophenone is used in the synthesis of triarylcarbinol analogs of fenarimol as potent inhibitors of Trypanosoma cruzi. It can also be used to prepare fatty acid amide hydrolase inhibitors.<br>References Keenan, M., et al.: J. Med. Chem., 55, 4189 (2012); Roughley, S., et al.: Bioorg. Med. Chem. Lett., 22, 901 (2012)<br></p>