Organic Halides

Applications 4-(4-Chlorophenyl)but-3-en-2-one (cas# 3160-40-5) is a useful research chemical.

Applications tert-Butyl Bromoacetate is a halogenated t-butyl acetate commonly used as an alkylating agent. tert-Butyl Bromoacetate is used in the synthesis of collagenase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Steinman, D.H. et al.: Bioorg. Med. Chem. Lett., 8, 2087 (1998); Fray, M.J. et al.: J. Med. Chem., 46, 3514 (2003): Neri, P. et al.: J. Org. Chem., 59, 3880 (1994);

Applications Reagent used in the preparation of fluorescent dyes and indicators.
References Link, J., et al.: J. Med. Chem., 48, 5295 (2005), Martin, V., et al.: Bioorg. Med. Chem. Lett., 15, 1851 (2005),

Applications 2-Bromophenetole

Applications 2-Bromoethyl Methyl Ether was used as a reactant for the preparation of alkyl ethers of β-alkylcholine salts.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Major, R.T., Cline, J.K.: J. Am. Chem. Soc., 55, 2504 (1933)

Applications 2,6-Diiodobenzene-1,4-diol is a metabolite of the antithyroid compound, Diacetyl-2,6-diiodoohydroquinone.
References Serif, George S., et al.: Biochem. Pharma., 12(8), 885-91 (1963)

Applications [4-(Cyclopropylmethyl)phenyl]methanamine Hydrochloride is a useful research chemical for organic synthesis.

Applications Substrate specificity of haloalkane dehalogenases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koudelakova, T., et al.: Biochem. J., 435, 345 (2011),

Applications 2,6-Difluorobenzyl alcohol

Applications 6-chloro-2,4-dimethylnicotinonitrile (cas# 101251-72-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Bromoacetic Acid Phenylmethyl Ester is used in the synthesis of somatostatin analogues with tumor-targeting properties . Also used in the synthesis of inhibitors of phospholipase A2, indolizine and indene derivatives.
References Heppeler, A. et al.: Chem. A. Eur. J., 5, 1974 (1999); Hagishita, S. et al.: J. Med. Chem., 39, 3636 (1996);

Applications 4-Chloro-2-nitrobenzenediazonium Chloride is reduced in the presence of hypophosphorous acid and carbon powder resulting in functionalized carbon powder with chloronitrophenyl groups attached on carbon particle surface;Also, it is an intermediate used in the synthesis of 2,4-Di-tert-butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol-d20 (D428017), which is an isotope labelled form of 2,4-Di-tert-butyl-6-(5-chloro-2H-benzotriazol-2-yl)phenol (D428015), which is a UV absorber.
References Pandurangappa, M., et al.: J. Solid State Electrochem., 12, 1411-1419 (2008); Moisan, J.: Eur. Polymer J., 16, 979 (1980); Nakata, H., et al.: Environ. Sci. Technol.,43, 6920 (2009)

Applications [(1-Fluoroethenyl)sulfinyl]benzene is an intermediate used in the synthesis of 13-Fluorodibenzo[a,i]pyrene (F588440), which is a polycyclic aromatic hydrocarbon (PAH) thus potentially exhibiting carcinogenic properties through activation of P450 mono-oxygenase enzymes. Also, it has unique electrical and optical properties due to being a conjugated macromolecule.
References Zhang, F. et al.: J. Org. Chem., 65, 3952 (2000); Amaladass, P. et al.: Tetra., 64, 7992 (2008);

Applications Bis(2,4,5-tribromophenyl)iodonium Hydrogen Sulfate is an intermediate in the synthesis of 2,2',4,4',5,6'-Hexabromodiphenyl ether (H290745), which is a hepatotoxic polybrominated diphenyl ester (PBDE) that is commonly used as a flame retardant. 2,2',4,4',5,6'-Hexabromodiphenyl ether is also sometimes found in food and meats as well, posing a significant risk to humans (especially during pregnancy) and/or animals that consume it. One of the new POPs under the Stockholm Convention
References Johnson, P., et al.: Sci. Total Environ., No vol. given, 445 (2013); Scott, L., et al.: Organo. Comp., 74, 1109 (2012); Zhao, Y., et al.: Env. Sci. Tech., 47, 5939 (2013)

Applications 2-Chloro-4-fluorobenzoic Acid s a useful synthetic intermediate. It can be used to prepare aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists. It can also be used to synthesize (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists.
References Barnett, H., et al.: Bioorg. Med. Chem. Lett., 19, 158 (2009); Tsukamoto, I., et al.: Bioog. Med. Chem., 16, 9524 (2008)

Applications N-​Methylcyclopropanami​ne Hydrochloride can be used as reactant/reagent in preparation of substituted benzazinones as antibacterial compounds.
References Jin, Q., et al.: PCT Int. Appl., WO 2017098440 A1 20170615 (2017)

Applications 1-fluoro-3,3-dimethyl-1$l^{3},2-benziodoxole (cas# 1391728-13-4) is a useful research chemical.

Applications Ethyl 2-(2,6-Dichlorophenyl)acetate (cas# 90793-64-9) is a useful research chemical.

Applications 1-azido-4-(bromomethyl)benzene (cas# 74489-49-9) is a useful research chemical.

Applications [4-[[4-(dimethylamino)phenyl]-(4-dimethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]phenyl]-trimethylazanium;dichloride (cas# 82-94-0) is a useful research chemical.

Applications Tetrabutylammonium Dibromochloride (cas# 64531-21-1) is a useful research chemical.

Applications 4-Fluorobenzotrifluoride

Applications 3-Chloro-2-fluorobenzyl Bromide (cas# 85070-47-9) is a compound useful in organic synthesis.

Applications 2,6-DIBROMO-3-PICOLINE (cas# 887571-15-5) is a useful research chemical.

Applications Ethyl 3,5-dichloro-4-hydroxybenzoate (cas# 17302-82-8) is a useful research chemical.

Applications 4-Pentylbromobenzene is a derivative of Valerophenone (V091450), which is an aromatic ketone that is often used as a tool in the study of various photochemical processes. Valerophenone is also an inhibitor of the enzyme carbonyl reductase.
References Lewis, F.D.: Mol. Photochem., 4, 49 (1972); Turro, N.J. et al.: Photochem. Photobiol., 26, 413 (1977); Imamura,Y. et al.: J. Enzyme Inhib. Med. Chem., 22, 105 (2007);

Applications SIB 1553A hyrdrochloride is a novel cognitive enhancer with selectivity for neuronal nicotinic acetylcholine receptors (nAChR).
References Vernier, J.M., et al.: J. Med. Chem., 42, 1684 (1999)

Stability Moisture Sensitive
Applications N,N-Dimethylphosphoramidodichloridate functions as a reagent used in the inhibition of acetylcholinestrase and butyryl cholinestrase by nerve agent surrogates. Also, the are used as reagents in the synthesis and in the antitumor activity of nonsymmetric phosphoric acid triamides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meek, E. C., et al.: Toxicol. Sci., 126, 525 (2012); Kosykhova, L., et al.: Pharm. Chem., 34, 525 (2000)

Applications Bis(2-bromoethyl)selenium dibromide is reacted with pyridine to synthesize hypervalent T-shaped coordination compounds. Bis(2-bromoethyl)selenium dibromide is also used as a transfer reagent to carry out the one-step alkoxyselenation of cyclohexene.
References Miura, M., et al.: J. Chem. Soc. Perk. T 1, No vol. given, 1719 (1995); Takanohashi, Y., et al.: J. Chem. Soc. Perk. T 1, No vol. given, 813 (1993)

Applications 3-Chloro-5-fluorobenzoic acid

Stability Hygroscopic
Applications 3-Amino-2-chloro-propenal is a chemical reagent in the synthesis of a COX-2 specific inhibitor.
References Davies, I. et al.: J. Org. Chem., 65, 8415 (2000);

Applications 2-Bromo-4-chlorophenol is a reactant in the preparation of 3-(2-(2,4-dichlorophenoxy)ethoxy)-6-methyl-2-nitropyridine selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonist.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Guerrero, M., et. al.: Bioorg. Med. Chem. Lett., 22, 537 (2012)

Applications N-(3-Aminopropyl)acetamide Hydrochloride salt is a salt form of N-Acetyl-1,3-propanediamine (A165390), which is an protected intermediate in the synthesis of analogs of Spermidine (S680400), an antineoplastic agent.
References Bergeron, R. et al.: J. Med. Chem, 40, 1475 (1997);

Applications Ethyl (pentafluorobenzoyl)acetate (cas# 3516-87-8) is a useful research chemical.

Applications 4-(Benzyloxy)aniline Hydrochloride is used as a reagent in the synthesis of a series of amino acid derivatives as novel chromogenic enzyme substrates for the detection of aminopeptidase activity in clinically important microorganisms.
References Cellier, M., et al.: Bioorg. Med. Chem., 22, 5249 (2014)

Applications N-allyl-2-chloro-acetamide (cas# 13269-97-1) is a useful research chemical.

Applications 1-Bromo-2-cyclohexylethane is a reagent used in the cross-coupling and Grignard reactions. It is used in the synthesis of immunosuppressive agents consisting of 5-phenylalkoxypsoralens as well as agonists for human vitamin-D resistant Rickets.
References Swann, S. et al.: J. Am. Chem. Soc., 124, 13795 (2002); Vennekamp, J. et al.: Mol. Pharm., 65, 1364 (2004); Bedford, R. et al.: Chem. Comm., 24, 2822 (2004); Lee, J. et al.: J. Am. Chem. Soc., 125, 5616 (2003);

Applications 2,3-Dichlorophenol-OD (CAS# 59457-02-2) is a useful isotopically labeled research compound. It can used for IR spectroscopy.
References Parthasarathy, S., et. al., J. Annamalai University, 30, 89-94, (1972);

Applications Leuco-2,6-dichlorophenolindophenol is the reduced form of DCIP and has been used to measure photocatalytic oxidation.
References Krysa, J.; et al.: Catalysis Today, 240, 132 (2015). Kafizas, A.; et al.: Chemistry - A European Journal, 18, 13048 (2012).

Applications 4-(2-Chlorophenyl)-cyclohexanone is used in the synthetic preparation of cyclohexyl pyridylpiperazines as Δ8-Δ7 sterol isomerase ligands with antiproliferative activity.
References Berardi, F., et al.: J. Med. Chem., 51, 7523 (2008)

Applications Methyl 5-chloropentanoate (cas# 14273-86-0) is a useful research chemical.

Stability Light Sensitive
Applications 2-Bromopropionic Acid Benzyl Ester (cas# 3017-53-6) is a compound useful in organic synthesis.

Applications 2-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)acetonitrile (cas# 68119-31-3) is a useful research chemical.

Stability Light Sensitive, Volatile
Applications cis-1-Bromo-1-propene is generally used as a reactant in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Aebly, Andrew H., et al.: Tetrahedron Let., 58(40), 3795-3799 (2017); Acharyya, Ranjan Kumar, et al.: J. of Org. Chem., 83(4), 2087-2103 (2018)

Applications 1-Bromopentane is a chemical reagent used in a multitude of organic syntheses. It is used iron-catalyzed alkylations of aromatic Grignard reagents via cross coupling. It is used in the synthesis of α,γ-diketo acids as reversible inhibitors of Hepatitis C virus NS5b RNA polymerase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cahiez, G. et al.: Angew. Chem. Int. Ed., 46, 4364 (2007); Summa, V. et al.: J. Med. Chem., 47, 14 (2004);

Stability Moisture Sensitive
Applications n-Octadecyltrichlorosilane (cas# 112-04-9) is a useful research chemical.
E0

Applications ethyl 4-aminopentanoate hydrochloride (cas# 119396-97-3) is a useful research chemical.

Applications Trimethyl Bromoorthoacetate is an intermediate in the synthesis of 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid (B444100), an impurity of Clavulanic Acid (C563750).
References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003),

Applications N-(2-acetyl-1-benzofuran-3-yl)-2-chloroacetamide (cas# 855715-46-7) is a useful research chemical.

Applications A reagent used in the preparation of hepatitis C virus NS3 protease inhibitors and PMPA prodrugs with antiretroviral activity.
References Sheng, X. et al.: Bioorg, Med. Chem. Lett., 169, 3453 (2009); Arimilli, M.N. et al.: Antiviral Chem. Chemother., 8, 557 (1997);

Applications 1,1',1''-[[(2-Bromoethyl)thio]methylidyne]trisbenzene is an intermediate in the synthesis of TETAC (P991915), a cyclen based compound used in paramagnetic NMR studies.
References Dhar, T. G., et al.: J. Med. Chem., 37, 2334 (1994);

Applications Methyl 6-Chloronicotinate is used in the determination of Acetamiprid (A150800) and its metabolites in crop and soil.
References Tokieda, M., et al.: Nippon Noyaku Gakkaishi, 24, 115 (1999)

Applications N-benzyl-2,2-dichloroacetamide (cas# 6063-50-9) is a useful research chemical.

Applications 2,3-Dimethylbenzotrifluoride (cas# 80245-28-9) is a useful research chemical.

Applications Chloromethyl Propyl Carbonate (cas# 35273-90-6) is a compound useful in organic synthesis.

Applications 9,​9-​Bis(methoxymethyl)​-​9H-​fluorene is a compound involved in the preparation of polypropylene by heterogeneous Ziegler-Natta catalyst.
References Luo, Z., et al.: Ind. Eng. Chem. Res., 54, 11247-11250 (2015)

Applications 3-(Difluoromethoxy)nitrobenzene (cas# 22236-07-3) is a useful research chemical.

Applications 1-Pyrenemethylamine Hydrochloride is used for labelling of various biomolecules. It is used as a reactant in self-assembling vancomycin-pyrene derivatives as hydrogel with potential medical applications. Also used in the preparation of 25,27-bis(ethylacetoethoxy)-26,28-dipropyloxycalix[4]arene.
References Xing, B., et al.: J. Am. Chem. Soc., 124, 14846 (2002); Kim, S., et al.: J. Am. Chem. Soc., 126, 16499 (2004);

Applications 5-Bromopentylboronic Acid

Applications 4-fluorobutanoic acid (cas# 462-23-7) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications tert-Butyl-(3-iodo-1,1-dimethyl-propoxy)-dimethyl-silane (cas# 105262-85-9) is used as a reagent in the preparation of Methyl Acetoacetate.
References Heslin, J. C., et al.: J. Chem. Soc. [Perkin 1]. 6, 1417 (1988)

Applications 4,4'-Dichlorodiphenyl Ether is a standard for environmental testing and research. Substance for the QSPR/QSAR models for prediction of physico-chemical properties and biological activity of polychlorinated diphenyl ethers.
References Xu, H., et al.: Chemosphere, 80, 665 (2010)

Stability Hygroscopic
Applications Methylbenzethonium Chloride is an anti-leishmanial agent, in the treatment of leishmaniasis, a zoonotic infection affecting people in tropical regions.
References El-On, J. et al.: Exp. Parasitol., 116, 156 (2007); Peniche, A. et al.: Antimicrob. Agents. Chemother., 58, 78 (2014);