Organic Halides

Applications (3-Phenoxyphenyl)methyl Ester 3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethyl-cyclopropanecarboxylic Acid is used in the preparation of agricultural chemicals.
References Thompson, W,. et al.: PCT Int. Appl., 2013

Applications 5-[2-(Trifluoromethyl)phenyl]-2-furoic Acid is a chemical reagent used in the preparation of novel TRPV1 antagonists. Also used in the preparation of potent inhibitors of FeII and MnII E, coli Methionine Aminopeptidase as antibacterial agents.
References Huguet, F. et al.: ChemMedChem. 7, 1020 (2012); Kim, N. et al.: Chem. Asian J., 8, 400 (2013);

Applications 1-Bromo-2-chloro-3-fluoro-4-(trifluoromethyl)-benzene is a useful synthetic intermediate.

Applications Methyl adipoyl chloride is a reagent that is used for improved heme-mimetics based on BAY 58-2667 (cinaciguat) and their effects on soluble guanylyl cyclase (sGC) activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References von Wantoch Rekowski, M., et al.: J. Med. Chem., 56, 8948 (2013);

Applications Bis[2-(2-chloroethoxy)ethyl] Ether, is an impurity in the synthesis of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (C365875), which is a polyethylene glycol used in the synthesis of novel glycolipids that bind HIV-1 cell surface glycoprotein Gp120 with potential application to pharmaceutical HIV-1 drugs. Also used in the synthesis of PET imaging agents targeting brain β-amyloid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References LaBell, R. et al.: Bioconj. Chem., 13, 143 (2002); Zhang, W. et al.: Nucl. Med. Biol., 32, 799 (2005);

Applications An intermediate in the preparation of Ondansetron impurities and organic polymers.

Applications 1,1-dimethylguanidine hydrochloride (cas# 22583-29-5) is a useful research chemical.

Applications 2,4-Dichloro-3-Nitrobenzotrifluoride is a useful reagent in the preparation of aryl ethers as HIF-2α inhibitors used in the treatment of cancers.
References Dixon, D. D., et al.: From PCT Int. Appl. (2015), WO 2015035223 A1 20150312

Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).
References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);

Applications 2-Bromo-4-aminobenzoic Acid (cas# 2486-52-4) is a compound useful in organic synthesis.

Applications 1,​1,​1,​2-​Tetrachloroethane is a chlorinated hydrocarbon and used as a solvent for cellulose, acetate, fat, waxes, greases, rubber, and sulfur. It is a contaminant in groundwater. 1,​1,​1,​2-​Tetrachloroethane can also induce heptotoxicity.Environmental contaminants; food contaminants.
References Lorah, M. M., and Olsen, L. D. Environ. Sci. Technol. 33, 227 (1999); Zheng, R. D., et al.: J Dig Dis. 13, 321 (2012)

Applications 3-Chloro-4'-fluoropropiophenone (cas# 347-93-3) is a useful research chemical.

Applications 4-Fluoro-1,2-phenylenediamine has shown anticancer activity in human prostate adenocarcinoma cell.
References Ahmed, H.A.: Bull. Faculty Pharmacy, 49, 25 (2011)

Applications 3-chloro-5-fluoro-4-hydroxybenzoic acid (cas# 455-57-2) is a useful research chemical.

Applications 7-Bromo-1-benzofuran
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1-(3,4-DICHLOROPHENYL)-3-DIMETHYLAMINO-1-PROPANONE HCL (cas# 75144-12-6) is a useful research chemical.

Applications Fumaryl Chloride is a reagent used in the synthesis of thermosetting resins which are widely used in industrial fields.
References Kudo, K. et al.: J. App. Polym. Sci., 133 (2016);

Applications 1-(2-Chloroethyl)-4-Fluorobenzene (cas# 332-43-4) is a useful research chemical.

Applications 2-t-Butyl-3-hydroxy-4-trifluoromethylisoindolin-1-one

Applications 4-fluorobutanoic acid (cas# 462-23-7) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Methyl 4-(trifluoromethoxy)benzoate

Applications 2-(chloromethyl)thiophene (cas# 765-50-4) is a useful research chemical.

Applications 4-[2,2-dichloro-1-(4-hydroxyphenyl)ethenyl]phenol (cas# 14868-03-2) is a useful research chemical.

Applications Coupling reagent for peptide synthesis and starting material for preparing other coupling reagents.

Applications O-TOLIDINE DIHYDROCHLORIDE (cas# 612-82-8) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2,3,4,5-Tetrafluorobenzoic Acid is used in the synthesis of diterpenoid analogs as antitumor compounds. Also used in the synthesis of novel quinoline lactones.
References Li, D. et al.: Eur. J. Med. Chem., 64, 215 (2013); Zheng, H. et al.: Lett. Org. Chem., 10, 252 (2013);

Applications tert-butyl 2-(4-(bromomethyl)phenyl)acetate (cas# 77292-91-2) is a useful research chemical.

Applications Methyl 2-Chloro-6-(trifluoromethyl)nicotinate (cas# 1073129-57-3) is a useful research chemical.

Applications 5-Chloronicotinic Acid is used as reagent/reactant luminescence and hydrothermal preparation of cobalt/cadmium/lead chloronicotinate phenanthroline MOF.
References Gao, Z.Q., et al.: J. Solid State Chem., 241, 121-130 (2016)

Stability Hygroscopic
Applications Methylbenzethonium Chloride is an anti-leishmanial agent, in the treatment of leishmaniasis, a zoonotic infection affecting people in tropical regions.
References El-On, J. et al.: Exp. Parasitol., 116, 156 (2007); Peniche, A. et al.: Antimicrob. Agents. Chemother., 58, 78 (2014);

Applications 2-Bromo-1-bromomethyl-5-chlorobenzene (cas# 66192-24-3) is a compound useful in organic synthesis.